Thursday, July 3, 2025 7/3/2025

The New England Precision Medicine Consortium of the All of Us Research Program

Award Number: OT2OD026553
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: OTHER
PERIOD OF PERFORMANCE START DATE: 03/01/2018
PERIOD OF PERFORMANCE END DATE: 05/31/2024

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The New England Precision Medicine Consortium of the All of Us Research Program - As part of the All of Us Research Program (AoURP), we have established the New England Precision Medicine Consortium (NEPMC), an enrollment center that encompasses two leading health care provider (HPO) organizations: Partners HealthCare System (PHS) and Boston Medical Center (BMC), the primary teaching hospital of Boston University School of Medicine (BU). Funding for the NEPMC began in October 2016 and over the following year, our consortium has actively participated in AoURP activities, workgroups, committees, task forces, and planning at all levels. The NEPMC began alpha phase enrollment on September 20, 2017 and beta phase enrollment on October 2, 2017. In the following sections, we provide detailed, milestone-driven descriptions of our plans to help achieve the AoURP's goals of building a research program of one million or more U.S. volunteers who are engaged as partners in a longitudinal, long-term effort to transform the understanding of factors contributing to individual health and disease. Our team, comprising diverse stakeholders (physicians, researchers, IT leaders, participants) will cohere to enroll 93,000 patients (46% BR) in service of the AoURP.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = -$206,929 )
2025	2023	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	21st Century Cures Act - Precision Medicine Initiative	000	1	1/10/2025	SUPPLEMENT FOR EXPANSION	-$206,929
														Subtotal = -$206,929

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	21st Century Cures Act - Precision Medicine Initiative	000	1	2/20/2024	SUPPLEMENT FOR EXPANSION	$0
2024	2018	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Trans-NIH Research Support	001	1	3/6/2024	NEW	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $6,925,000 )
2023	2023	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	21st Century Cures Act - Precision Medicine Initiative	003	1	8/22/2023	SUPPLEMENT FOR EXPANSION	$25,000
2023	2023	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	21st Century Cures Act - Precision Medicine Initiative	002	1	5/10/2023	SUPPLEMENT FOR EXPANSION	$0
2023	2023	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	21st Century Cures Act - Precision Medicine Initiative	001	1	2/28/2023	SUPPLEMENT FOR EXPANSION	$6,900,000
2023	2018	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Trans-NIH Research Support	000	1	2/27/2023	NEW	$0
														Subtotal = $6,925,000

Issue Date FY: 2022 ( Subtotal = $9,700,000 )
2022	2022	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	21st Century Cures Act - Precision Medicine Initiative	002	1	3/28/2022	SUPPLEMENT FOR EXPANSION	$9,700,000
2022	2021	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Trans-NIH Research Support	000	1	11/16/2021	SUPPLEMENT FOR EXPANSION	$0
2022	2018	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Trans-NIH Research Support	001	1	3/4/2022	NEW	$0
														Subtotal = $9,700,000

Issue Date FY: 2021 ( Subtotal = $8,175,000 )
2021	2021	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Trans-NIH Research Support	002	1	2/28/2021	SUPPLEMENT FOR EXPANSION	$8,175,000
2021	2021	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Trans-NIH Research Support	003	1	7/21/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2020	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	21st Century Cures Act - Precision Medicine Initiative	000	1	1/11/2021	SUPPLEMENT FOR EXPANSION	$0
2021	2018	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Trans-NIH Research Support	001	1	2/28/2021	NEW	$0
														Subtotal = $8,175,000

Issue Date FY: 2018 ( Subtotal = $12,000,000 )
2018	2018	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Trans-NIH Research Support	000	1	2/28/2018	NEW	$9,000,000
2018	2018	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Trans-NIH Research Support	001	1	7/25/2018	NEW	$3,000,000
														Subtotal = $12,000,000

Grand Total All Awards = $36,593,071

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The New England Precision Medicine Consortium of the All of Us Research Program

Award Number: OT2OD026553

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: OTHER

PERIOD OF PERFORMANCE START DATE: 03/01/2018

PERIOD OF PERFORMANCE END DATE: 05/31/2024

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