A Comprehensive Public Health Approach to Asthma Control Through Evidence-Based Interventions - ABSTRACT Building a Pathway to Health Equity for Missouri’s Children with Asthma Missouri Asthma Prevention and Control Program Established in 2001, the Missouri Asthma Prevention and Control Program (MAPCP) has developed significant experience building partnerships and leveraging resources to improve asthma outcomes for children. Past and future success is supported by a strong leadership team with expertise in asthma care improvement and public health program management, including twenty three consecutive years in service to MAPCP’s growth and development. In addition, an alliance of long-standing strategic partners supports the implementation of multi-component asthma care improvement strategies. These partners will help schools, clinics, public health agencies, health plans, universities, and hospitals work together to improve specific geographic areas or implement statewide strategies. The latest state plan, Aligned for Impact 2020-2024: The Missouri Plan for Asthma Care Management, sets goals to improve health equity through innovative approaches to school-based services, population health management practices, home environment assessment, technology, advocacy, and leadership. The proposed plans for EH-24-0016 call for using data to identify communities with the highest need and disproportionate evidence of health inequity. The MAPCP’s planned strategies will advance health equity and sustainability by improving the capabilities of schools to provide self-management education, health systems to deliver high quality, guideline-based care, and home visitors to provide home environmental assessments. This work is supported by healthcare policy actions, including a Medicaid State Plan Amendment that covers home visit services for children enrolled in MO HealthNet and the state Medicaid pharmacy program requiring guideline-based medication management. The MAPCP will implement, evaluate, and improve activities across all six evidence-based strategies of the EXHALE framework: (1) self-management education, (2) smoking, (3) home environment assessments, (4) guidelines-based medical management, (5) care coordination and (6) environmental policy. By focusing multi-component strategies in selected communities, the MAPCP will contribute to reducing asthma-related emergency department visits, hospitalizations, mortality, and disparities. . The proposed workplan calls for delivering results by: 1. Increased coordination of care across settings. 2. Reduced exposure to environmental asthma triggers. 3. Improved sustainability of results-based health equity partnerships. 4. Increased policies/plans enacted and evaluated to address drivers of asthma control. The MAPCP’s robust capacity for evaluation is made possible by many partners that contribute data and collaborate to prioritize activities. Consistent with utilization-focused theory, evaluation projects are designed to generate results are meaningful to real users and contribute directly to continuous quality improvement. Surveillance, partnerships, and communications are other organizational strengths that enable pursuit of excellence and achievement of long-term outcomes – better asthma care, lower costs, and improved health status.