The Indiana State Department of Health, Division of HIV, STD, Viral Hepatitis (ISDH) HIV Surveillance Programs (Surveillance Program) and HIV Prevention (Prevention Program) are committed to fully integrated, data driven approaches to the prevention and eventual elimination of new HIV infections in Indiana and beyond. In 2015, Indiana experienced one of the largest outbreaks of HIV in history. In collaboration with federal, state, and local public health, mental health, and medical providers along with other public and private entities managed the event and supported over 75% of those identified as part of the outbreak to being virally suppressed. Unfortunately, this funding announcement does not include this critical event in the history of HIV in Indiana and nationally. As such, resources needed to maintain this high level of viral suppression in cases associated with the outbreak and statewide are not accounted for in the appropriation of national funding. Despite this significant challenge, the ISDH is committed to the health and well-being of all of its residents and will work closely with CDC to ensure that they are cared for. The ISDH Division of HIV, STD,Viral Hepatitis is a fully integrated HIV, STD, viral hepatitis prevention, care, and surveillance program serving the state through integrated approaches to multifaceted factors impacting the whole health of communities and the individuals within. Within the 2018- 2022 funding period, the Surveillance and Prevention Programs will further collaborate for the collection and analysis of program data to inform disease prevention and linkage to care activities. The following application packet outlines the goals, objectives, activities, and evaluation process that the Surveillance and Prevention Programs will engage in to reach the ultimate goal of eliminating new cases of HIV in Indiana.