In this application for CDC’s FOA PS18-1802: Integrated HIV Surveillance and Prevention Programs for Health Departments, the Washington State Department of Health (DOH) will continue to build on collaborative relationships with health and social services agencies around the state to strengthen comprehensive patient-centered interventions to locate and treat persons with HIV disease and protect people at high risk of HIV infection. DOH proposes innovative opportunities to realize new data collection and data sharing systems at DOH and with partner agencies which will reinforce Data-to-Care systems with dynamic HIV/STD partner and medical case management services integrated with community mobilization and broad social and health systems transformation goals designed to keep HIV negative persons healthy and ensure continuity of integrated care for persons living with HIV disease. DOH will implement a variety of interventional disease surveillance strategies and activities for the purpose of early detection and reporting of HIV, identifying and minimizing transmission clusters and maximizing viral suppression. In this application, DOH demonstrates its success implementing an HIV PrEP drug assistance program across the state, with support leveraging resources from local health jurisdictions, community based organizations and research institutions. DOH highlights current progress implementing long-term goals to end the HIV epidemic in the state, outlined in Washington State Governor Inslee’s End AIDS Washington initiative. Other outcomes of this project include responding to clusters of newly identified cases, enhancing on-going patient monitoring and follow up capacity, establishing a network of pharmacies prescribing PrEP, and developing model resources to improve case investigation and surveillance practices.