Wisconsin's application for the Overdose Data to Action in States. - Wisconsin has collaborated across multiple state agencies to develop a multifaceted, multidisciplinary approach that is equally complex as the overdose epidemic. There have been successful initiatives, and data indicate we are moving in the right direction. It is with our collective knowledge, experience, and data that the Division of Public Health (DPH) at the Wisconsin (WI) Department of Health Services (DHS) seeks approximately $4,483.777 in funding for activities in nine key surveillance and public health strategy areas. DPH recognizes the need and benefit of programming based on surveillance data. DPH will develop a rapid and comprehensive data reporting strategy to target overdose prevention activities and inform prevention programming. There will be enhanced surveillance infrastructure to improve timeliness of data systems, as well as linkages across systems. Wisconsin is applying for two optional strategies including biosurveillance to increase toxicology testing of biological specimens in order to provide contextual information related to overdoses, and data linkages to link person-level data across systems to inform trends in non-fatal and fatal overdoses. WI will be able to develop a more comprehensive understanding of how a person who experiences an overdose interacts with the public health and health care systems and how those systems can better respond to the needs of individuals and the community. DPH has developed strong relationships with local partners and plans to expand these through increased data literacy and capacity to respond as our existing pilot alert system is transitioned to a statewide system (Wisconsin Suspected Overdose Alerts for Rapid Response - WiSOARR); enhanced syndromic data collection, dissemination, and annual discharge data reporting; improved tracking of unintentional and undetermined overdose deaths; and improved data linkages. DPH staff have years of experience providing and coordinating harm reduction efforts across the state. We will use this knowledge to improve systems and service delivery for people who use drugs throughout the state, while also focusing on disproportionately impacted populations and underserved areas. Prevention strategies will include: • provision and implementation of the Wisconsin Dental Pain Protocol (WDPP) project which addresses non-traumatic dental pain protocols in emergency departments and linking patients to after-care; • increased education and support for clinicians on opioid use disorder (OUD) and stimulant use disorder (StUD); • expansion of the ED2Recovery peer support program to the northwest part of the state; • continued support for the maintenance of the Prescription Drug Monitoring Program (PDMP), including supporting data integration across state lines; • continued support for the overdose fatality review (OFR) program including the State OFR Advisory Group, state training and technical assistance provider, and dissemination of DPH and Department of Justice (DOJ) linked data; • creation of regional harm reduction technical assistance centers (HRTAC) to support harm reduction education and training, harm reduction supply distribution, and the use of navigators to increase access to harm reduction services and other resources for people who use drugs; • provision of culturally sensitive, anti-stigmatizing messaging and education that can be tailored for local needs; and • the creation of post-overdose response teams with navigators through the HRTACs to link individuals who have experienced an overdose, or are at high risk of an overdose, to additional care within 72 hours.