Wednesday, April 24, 2024 4/24/2024

Leveraging existing HIV differentiated service delivery models to screen and treat hypertension in Ugandan persons living with HIV for dual control

Award Number: K43TW011963
ORGANIZATION: FOGARTY INTERNATIONAL CENTER
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Group Awards By Issue Date FY or Funding FY:

View Award Abstract

Project summary Increased access to antiretroviral therapy has improved survival among persons living with HIV (PLHIV) and increased the proportion of elderly PLHIV (=50 years) to >20% worldwide. Aging PLHIV experience higher rates of chronic non-communicable diseases (NCDs) including hypertension (HTN), kidney dysfunction, diabetes mellitus, metabolic syndrome and hyperlipidemia due to the ART and HIV-associated chronic inflammation. Concurrent administration of ART and medications for hypertension and other NCDs also raises concerns for medication-related adverse events, including adverse signs and symptoms and laboratory abnormalities. Little is known about the frequency or severity of adverse medication events among aging PLHIV in low-income countries like Uganda. The Uganda national guidelines for HIV management recommend monitoring for hypertension medication adverse events among PLHIV. However, adverse events monitoring is not happening routinely. In our parent K43 project, we are using implementation science methods and a quasi- experimental trial to compare clinic and community-based models for treating aging hypertensive PLHIV, following Uganda national treatment guidelines. To address the epidemiologic and implementation gap on adverse event monitoring, we have developed the current supplement proposal to add several research question to our K43 cohort to characterize the incidence, types, severity and predictors of hypertension medication adverse events among aging PLHIV and inform the development of management approaches. This study will generate pilot data for future research to evaluate the implementation, effectiveness, and costs of an adverse events screening and management strategy and decision aid for providers and patients.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = $213,400 )
2023	2023	INFECTIOUS DISEASES RESEARCH COLLABORATION	PLOT 2C NAKASERO HILL ROAD	KAMPALA				UGA	International Research and Research Training	002	3	9/18/2023	SUPPLEMENT FOR EXPANSION	$100,000
2023	2023	INFECTIOUS DISEASES RESEARCH COLLABORATION	PLOT 2C NAKASERO HILL ROAD	KAMPALA				UGA	International Research and Research Training	000	3	6/1/2023	NON-COMPETING CONTINUATION	$113,400
2023	2023	INFECTIOUS DISEASES RESEARCH COLLABORATION	PLOT 2C NAKASERO HILL ROAD	KAMPALA				UGA	International Research and Research Training	001	3	6/8/2023	NON-COMPETING CONTINUATION	$0
														Subtotal = $213,400

Issue Date FY: 2022 ( Subtotal = $113,400 )
2022	2022	INFECTIOUS DISEASES RESEARCH COLLABORATION	PLOT 2C NAKASERO HILL ROAD	KAMPALA				UGA	International Research and Research Training	000	2	5/20/2022	NON-COMPETING CONTINUATION	$113,400
														Subtotal = $113,400

Issue Date FY: 2021 ( Subtotal = $113,400 )
2021	2021	INFECTIOUS DISEASES RESEARCH COLLABORATION	PLOT 2C NAKASERO HILL ROAD	KAMPALA				UGA	International Research and Research Training	000	1	9/14/2021	NEW	$113,400
														Subtotal = $113,400

Grand Total All Awards = $440,200

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Leveraging existing HIV differentiated service delivery models to screen and treat hypertension in Ugandan persons living with HIV for dual control

Award Number: K43TW011963

ORGANIZATION: FOGARTY INTERNATIONAL CENTER

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer