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Understanding the role of schools in supporting HIV treatment outcomes among HIV infected adolescents

Award Number: K43TW011422
ORGANIZATION: FOGARTY INTERNATIONAL CENTER
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 08/17/2020
PERIOD OF PERFORMANCE END DATE: 07/31/2025

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Understanding the role of schools in supporting HIV treatment outcomes among HIV infected adolescents - PROJECT SUMMARY/ABSTRACT The overall goal of the proposed K43 Emerging Global Leader Award (non-clinical trials requirement) is to support Dr. Njuguna’s research training to develop an independent career in HIV research. Dr. Njuguna is a research scientist at the Kenyatta National Hospital, Nairobi, Kenya. The proposed work examines the unique intersection between education and health in the context of adolescent HIV. Dr. Njuguna’s training goals are to gain expertise in human centered design for intervention development, implementation science (IS), mixed methods and adolescent research. This work will also provide an opportunity to work closely with policy makers, and link clinical epidemiology skills she has previously acquired with real world IS methods. The proposal leverages a multidisciplinary team of mentors and collaborators who will ultimately support Dr. Njuguna’s goal to become a productive and influential independent investigator in adolescent HIV research. The research goal of this proposal is to use a human centered design approach by utilizing mixed methods research to gain an in-depth understanding of the school environment and its contribution to achieving treatment goals, and to collaboratively and iteratively develop a school-based intervention to improve outcomes among school-going adolescents living with HIV (ALWHIV). There is a growing population of ALWHIV surviving to adulthood. These children need support to sustain medication use during adolescence and across school and life transitions. There is limited evidence on school-based interventions to support treatment, despite the fact that most ALWHIV are enrolled in school (including boarding schools). The Aims of this proposal are: 1.To evaluate existing school-based structures available for ALWHIV and key determinants of caregiver and ALWHIV school choice decisions, 2.To determine school-related correlates of viral suppression and retention in care, 3.To develop and pilot a school staff training and peer support intervention in selected schools for non-health outcomes (acceptability, feasibility and appropriateness). This is the first study to our knowledge to propose to quantitatively characterize school-related correlates of clinical outcomes in sub-Sahara Africa (SSA) and evaluate factors influencing school choice for ALWHIV. The study brings together a diverse team of stakeholders from the Kenyan national Education and Health sectors and utilizes a multi-step approach to achieve study objectives. This approach will allow for rigorous intervention development process, and pave way for a strong collaborative effort in a future R01 to test effectiveness of a school-based intervention package to improve outcomes, including viral suppression, in school-going ALWHIV, that could potentially benefit adolescents with other non-HIV chronic illnesses. Dr. Njuguna’s research goals correspond with her training goals, and at the completion of this award, she will be in an excellent position to submit an R01 application to further advance research in ALWHIV.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $122,601 )
2024	2024	KENYATTA NATIONAL HOSPITAL	HOSPITAL ROAD	NAIROBI				KEN	International Research and Research Training	000	5	8/2/2024	NON-COMPETING CONTINUATION	$122,601
														Subtotal = $122,601

Issue Date FY: 2023 ( Subtotal = $119,619 )
2023	2023	KENYATTA NATIONAL HOSPITAL	HOSPITAL ROAD OFF NGONG ROAD	NAIROBI				KEN	International Research and Research Training	000	4	7/30/2023	NON-COMPETING CONTINUATION	$119,619
														Subtotal = $119,619

Issue Date FY: 2022 ( Subtotal = $116,597 )
2022	2022	KENYATTA NATIONAL HOSPITAL	HOSPITAL ROAD OFF NGONG ROAD	NAIROBI				KEN	International Research and Research Training	000	3	7/27/2022	NON-COMPETING CONTINUATION	$116,597
														Subtotal = $116,597

Issue Date FY: 2021 ( Subtotal = $121,893 )
2021	2021	KENYATTA NATIONAL HOSPITAL	HOSPITAL ROAD OFF NGONG ROAD	NAIROBI				KEN	International Research and Research Training	002	2	9/10/2021	NON-COMPETING CONTINUATION	$0
2021	2021	KENYATTA NATIONAL HOSPITAL	HOSPITAL ROAD OFF NGONG ROAD	NAIROBI				KEN	International Research and Research Training	001	2	8/12/2021	NON-COMPETING CONTINUATION	$121,893
2021	2020	KENYATTA NATIONAL HOSPITAL	HOSPITAL ROAD OFF NGONG ROAD	NAIROBI				KEN	International Research and Research Training	000	1	6/4/2021	NEW	$0
														Subtotal = $121,893

Issue Date FY: 2020 ( Subtotal = $122,747 )
2020	2020	KENYATTA NATIONAL HOSPITAL	HOSPITAL ROAD OFF NGONG ROAD	NAIROBI				KEN	International Research and Research Training	000	1	8/14/2020	NEW	$122,747
														Subtotal = $122,747

Grand Total All Awards = $603,457

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Understanding the role of schools in supporting HIV treatment outcomes among HIV infected adolescents

Award Number: K43TW011422

ORGANIZATION: FOGARTY INTERNATIONAL CENTER

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 08/17/2020

PERIOD OF PERFORMANCE END DATE: 07/31/2025

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