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Implementing mental health interventions for pregnant adolescents in primary care LMIC contexts

Award Number: K43TW010716
ORGANIZATION: FOGARTY INTERNATIONAL CENTER
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)
PERIOD OF PERFORMANCE START DATE: 09/20/2018
PERIOD OF PERFORMANCE END DATE: 02/28/2024

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Implementing mental health interventions for pregnant adolescents in primary care LMIC contexts - SUMMARY High prevalence of adolescent pregnancies in low-and-middle-income countries (LMICs) has resulted in a tremendous public health burden. Many adolescent pregnancies are unwanted, unplanned, and outside of marriage. When adolescent girls become mothers, their opportunities for economic and educational growth are limited. A burgeoning number of adolescent mothers from LMICs are also marginalized due to poverty or gender-based traditions, which further limit their access to health resources, social protection/ support and personal development. Structural inequalities and adverse circumstances have resulted in high prevalence of depression in adolescent mothers. Despite the enormous mental health needs for adolescent mothers in LMICs, child and adolescent mental health service remains in its’ infancy. There is a need to advance cultural and context-sensitive perinatal depression interventions that can align with adolescents’ living contexts and developmental needs and simultaneously address multiple resource challenges in provision of mental health care in LMIC settings. This application seeks to respond to these adolescent perinatal depression intervention and implementation research gaps by i) utilizing WHO Mental Health Treatment Gap Action Program (mhGAP) and Group Interpersonal psychotherapy (IPT-G) depression care packages that has shown to be efficacious for adult depression, and further test the approaches in adolescents with perinatal depression in Kenyan maternal and child health (MCH) service settings. Three key research questions will be studied: (i) how to improve fit of the mhGAP/IPT-G-depression intervention model for pregnant adolescents in Kenya, (ii) how to effectively integrate task-shifting/sharing and collaborative strategies with MCH clinical workflow to implement mhGAP/IPT-G depression intervention for pregnant adolescents in MCH settings, and (iii) whether the adapted mhGAP/IPT-G are feasible-acceptable-effective in addressing perinatal depression in adolescents. Considering the demand-resource gap, as MCH clinics usually serve high volume of adolescents with perinatal depression but have limited resources, this study will also explore other cost-effective strategies, such as study feasibility of applying long and mini version of IPT-G and other family/adolescent peer co-lead approach of intervention implementation. This study will be carried out using a cross-disciplinary partnership approach. The specific aims of this study are to: 1) explore barriers and strategies to improve mhGAP-IG/IPT-G fit and implementation for adolescent perinatal depression in MCH clinics in Kenya; 2) Develop adapted version of IPT-G/ and mhGAP-IG, and build MCH capacity for implementation; and 3) test feasibility and implementation-effectiveness outcomes for the adapted version of mhGAP-IG/ IPT-G.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2022	UNIVERSITY OF NAIROBI	UNIVERSITY WAY IN NAIROBI CENTRAL BUSINESS DISTRICT.	NAIROBI				KEN	International Research and Research Training	000	5	10/29/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $0 )
2023	2022	UNIVERSITY OF NAIROBI	UNIVERSITY WAY	NAIROBI				KEN	International Research and Research Training	000	5	4/26/2023	NON-COMPETING CONTINUATION	$0
2023	2022	UNIVERSITY OF NAIROBI	UNIVERSITY WAY	NAIROBI				KEN	International Research and Research Training	001	5	4/26/2023	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $188,845 )
2022	2022	UNIVERSITY OF NAIROBI	UNIVERSITY WAY	NAIROBI				KEN	International Research and Research Training	001	5	9/9/2022	SUPPLEMENT FOR EXPANSION	$80,845
2022	2022	UNIVERSITY OF NAIROBI	UNIVERSITY WAY	NAIROBI	NULL			KEN	International Research and Research Training	000	5	3/3/2022	NON-COMPETING CONTINUATION	$108,000
														Subtotal = $188,845

Issue Date FY: 2021 ( Subtotal = $108,000 )
2021	2021	UNIVERSITY OF NAIROBI	UNIVERSITY WAY	NAIROBI				KEN	International Research and Research Training	000	4	4/30/2021	NON-COMPETING CONTINUATION	$108,000
														Subtotal = $108,000

Issue Date FY: 2020 ( Subtotal = $145,800 )
2020	2020	UNIVERSITY OF NAIROBI	UNIVERSITY WAY	NAIROBI				KEN	International Research and Research Training	001	3	9/11/2020	SUPPLEMENT FOR EXPANSION	$37,800
2020	2020	UNIVERSITY OF NAIROBI	UNIVERSITY WAY	NAIROBI				KEN	International Research and Research Training	000	3	2/20/2020	NON-COMPETING CONTINUATION	$108,000
														Subtotal = $145,800

Issue Date FY: 2019 ( Subtotal = $102,600 )
2019	2019	UNIVERSITY OF NAIROBI	UNIVERSITY WAY	NAIROBI				KEN	International Research and Research Training	001	2	4/18/2019	NON-COMPETING CONTINUATION	$102,600
2019	2018	UNIVERSITY OF NAIROBI	UNIVERSITY WAY	NAIROBI				KEN	International Research and Research Training	000	1	1/31/2019	NEW	$0
														Subtotal = $102,600

Issue Date FY: 2018 ( Subtotal = $102,600 )
2018	2018	UNIVERSITY OF NAIROBI	UNIVERSITY WAY	NAIROBI				KEN	International Research and Research Training	000	1	9/19/2018	NEW	$102,600
														Subtotal = $102,600

Grand Total All Awards = $647,845

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Implementing mental health interventions for pregnant adolescents in primary care LMIC contexts

Award Number: K43TW010716

ORGANIZATION: FOGARTY INTERNATIONAL CENTER

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

PERIOD OF PERFORMANCE START DATE: 09/20/2018

PERIOD OF PERFORMANCE END DATE: 02/28/2024

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