Sunday, July 6, 2025 7/6/2025

Mentored Patient-Oriented Research for Preventing ASCVD Events

Award Number: K24HL136852
ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 01/01/2018
PERIOD OF PERFORMANCE END DATE: 03/31/2028

Group Awards By:

View Award Description

Mentored Patient-Oriented Research for Preventing ASCVD Events - Project Summary/Abstract Dr, Mora is a cardiologist cross-trained in epidemiology who has devoted her career to patient-oriented research (POR) in cardiovascular prevention, focusing on the discovery and translational applications of lipid biomarkers of cardiometabolic disease risk, and developing innovative approaches and therapies for preventing cardiometabolic disease. Her POR research has impacted national and international guidelines for clinical practice, In the first K24 cycle, she has mentored more than fifteen preand postdoctoral trainees in POR projects related to lipids, statins, and cardiovascular risk. This has been highlighted in recent years by the achievements of her mentees in presenting their work nationally and internationally, The K24 renewal award will allow her to extend her successful mentoring program. The overall goals of this K24 award are to 1) grow and expand her POR program by providing the next-generation of cardiovascular investigators with opportunities for precision POR in prevention by incorporating technologic advances in high-throughput metabolomics with clinical and health record data as a strategy to improve cardiovascular outcomes; and 2) strengthen and build upon her mentoring program in global cardiovascular health by expanding her POR program to examine cardiometabolic risk factors contributing to premature cardiovascular events. Cardiovascular disease remains the number one cause of death globally, and > 70% of cases can be attributed to cardiometabolic risk factors. Patients with uncontrolled cardiometabolic risk factors are at high risk of suffering from premature and recurrent cardiovascular events. The candidate's ongoing POR projects, exceptional institutional resources, and cost-effective local and international collaborations provide a nurturing environment for the training and career development of junior investigators in POR cardiovascular research. The new research aims proposed in this award will examine a panel of targeted metabolomics with risk of cardiovascular disease from diverse patient populations to better understand how cardiometabolic risk factors could be targeted for precision preventative diagnostic and therapeutic targets. This research program will provide excellent POR opportunities for junior investigators and trainees to be mentored across the full spectrum of clinical, epidemiological, and molecular studies. Results from this mentored POR program will guide future efforts directed at cardiovascular screening, risk stratification, and potentially more targeted precision medicine interventions to improve cardiovascular health. Towards that end, this K24 award will facilitate the progress of Dr, Mora's mentees into the next generation of patient-oriented independent cardiovascular researchers.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $126,184 )
2025	2025	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cardiovascular Diseases Research	002	8	5/12/2025	NON-COMPETING CONTINUATION	$126,184
2025	2023	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cardiovascular Diseases Research	001	6	1/30/2025	COMPETING CONTINUATION	$209
2025	2022	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cardiovascular Diseases Research	000	5	1/30/2025	NON-COMPETING CONTINUATION	-$209
														Subtotal = $126,184

Issue Date FY: 2024 ( Subtotal = $126,184 )
2024	2024	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cardiovascular Diseases Research	000	7	4/11/2024	NON-COMPETING CONTINUATION	$126,184
														Subtotal = $126,184

Issue Date FY: 2023 ( Subtotal = $126,184 )
2023	2023	BRIGHAM & WOMENS HOSPITAL INC	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cardiovascular Diseases Research	000	6	3/24/2023	COMPETING CONTINUATION	$126,184
														Subtotal = $126,184

Issue Date FY: 2022 ( Subtotal = $120,470 )
2022	2022	BRIGHAM AND WOMEN'S HOSPITAL, INC., THE	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cardiovascular Diseases Research	000	5	1/7/2022	NON-COMPETING CONTINUATION	$120,470
														Subtotal = $120,470

Issue Date FY: 2021 ( Subtotal = $120,470 )
2021	2021	BRIGHAM AND WOMEN'S HOSPITAL, INC., THE	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cardiovascular Diseases Research	000	4	1/1/2021	NON-COMPETING CONTINUATION	$120,470
														Subtotal = $120,470

Issue Date FY: 2020 ( Subtotal = $120,470 )
2020	2020	BRIGHAM AND WOMEN'S HOSPITAL, INC., THE	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cardiovascular Diseases Research	000	3	1/24/2020	NON-COMPETING CONTINUATION	$120,470
														Subtotal = $120,470

Issue Date FY: 2019 ( Subtotal = $120,470 )
2019	2019	BRIGHAM AND WOMEN'S HOSPITAL, INC., THE	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cardiovascular Diseases Research	000	2	1/4/2019	NON-COMPETING CONTINUATION	$120,470
														Subtotal = $120,470

Issue Date FY: 2018 ( Subtotal = $120,470 )
2018	2018	BRIGHAM AND WOMEN'S HOSPITAL, INC., THE	75 FRANCIS ST	BOSTON	MA	02115	SUFFOLK	USA	Cardiovascular Diseases Research	000	1	12/22/2017	NEW	$120,470
														Subtotal = $120,470

Grand Total All Awards = $980,902

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Mentored Patient-Oriented Research for Preventing ASCVD Events

Award Number: K24HL136852

ORGANIZATION: NATIONAL HEART, LUNG, & BLOOD INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 01/01/2018

PERIOD OF PERFORMANCE END DATE: 03/31/2028

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer