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Mentorship in Clinical Complementary and Integrative Health Research

Award Number: K24AT011568
ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 09/01/2024
PERIOD OF PERFORMANCE END DATE: 07/31/2027

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Mentorship in Clinical Complementary and Integrative Health Research - Because over 50% of adults in the United States take complementary and integrative health (CIH) natural products for their health, the training of CIH practitioners and scientists to produce high-quality clinical research is imperative to identifying effective products for the safety of the public. As such, this proposal requests a K24 mid-career development award to expand and support mentorship in clinical natural product research by Dr. Ryan Bradley, ND, MPH. Dr. Bradley has demonstrated effective mentorship by the publication of all past mentees, and the progression of multiple mentees from graduate students to formal NIH post-doctoral training awards, and independent training awards. Dr. Bradley is currently a co-Director of the Scholars program within the RAND REACH Center where he provides mentorship for 10 Scholars, and a Program Director and mentor in the NCCIH-funded T90/R90 Building Research across Interdisciplinary Gaps (BRIDG) clinical research training program. Additionally, Dr. Bradley provides mentorship for numerous post-doctoral trainees, including CIH clinicians and PhD scientists. Dr. Bradley is a primary mentor for a trainee in the University of Michigan HEAL K12 program; a T90 trainee who has progressed onto a KL2 award at the UW, a CIH practitioner supported by an NICCH administrative supplement to gain research experience on Dr. Bradley's R01-funded clinical trials, and two post-doctoral trainees from CIH backgrounds in the ORCCAMIND T32 program at Oregon Health & Sciences University. In addition to his position as an Associate Professor in the School of Public Health at UC San Diego, he retains affiliate and adjunct appointments at 2 US-based and 2 international universities, thus Dr. Bradley is extremely well connected to assist mentees in identifying resources and collaborators for their research. The Specific Aims of this proposal are for Dr. Bradley to: 1. Dedicate consistent effort in the mentorship of promising trainees in T32, T90, R90, K and REACH Scholar programs in order to facilitate their progression in research training and independent research (Aim 1); 2. Refine and develop mentoring skills by pursuing additional training in research mentorship and cutting-edge translational science methodologies (Aim 2); and 3. Provide exposure to translational science methods and provide publication opportunities for mentees through the collection of additional preliminary data related to recent clinical trials of specialized pro-resolvin mediators (SPM) and xanthohumol natural products, including product quality assessment, measurement of relevant biomarkers in stored biologic samples, and measurement of additional transcription factors (PCSK9) to extend the research to new clinical populations (Aim 3).


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2025	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Research and Training in Complementary and Integrative Health	000	5	5/4/2026	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $148,727 )
2025	2025	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Research and Training in Complementary and Integrative Health	001	5	7/24/2025	NON-COMPETING CONTINUATION	$148,727
2025	2023	NATIONAL UNIVERSITY OF NATURAL MEDICINE	49 S PORTER ST	PORTLAND	OR	97201	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	000	3	6/2/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $148,727

Issue Date FY: 2024 ( Subtotal = $148,727 )
2024	2024	UNIVERSITY OF CALIFORNIA, SAN DIEGO	9500 GILMAN DR	LA JOLLA	CA	92093	SAN DIEGO	USA	Research and Training in Complementary and Integrative Health	001	4	8/23/2024	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$148,727
2024	2023	NATIONAL UNIVERSITY OF NATURAL MEDICINE	49 S PORTER ST	PORTLAND	OR	97201	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	000	3	8/23/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $148,727

Issue Date FY: 2023 ( Subtotal = $155,208 )
2023	2023	NATIONAL UNIVERSITY OF NATURAL MEDICINE	49 S PORTER ST	PORTLAND	OR	97201	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	000	3	8/2/2023	NON-COMPETING CONTINUATION	$155,208
														Subtotal = $155,208

Issue Date FY: 2022 ( Subtotal = $156,867 )
2022	2022	NATIONAL UNIVERSITY OF NATURAL MEDICINE	49 S PORTER ST	PORTLAND	OR	97201	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	000	2	7/22/2022	NON-COMPETING CONTINUATION	$156,867
														Subtotal = $156,867

Issue Date FY: 2021 ( Subtotal = $152,122 )
2021	2021	NATIONAL UNIVERSITY OF NATURAL MEDICINE	49 S PORTER ST	PORTLAND	OR	97201	MULTNOMAH	USA	Research and Training in Complementary and Integrative Health	000	1	7/29/2021	NEW	$152,122
														Subtotal = $152,122

Grand Total All Awards = $761,651

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Mentorship in Clinical Complementary and Integrative Health Research

Award Number: K24AT011568

ORGANIZATION: CENTER FOR DRUG EVALUATION AND RESEARCH, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 09/01/2024

PERIOD OF PERFORMANCE END DATE: 07/31/2027

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