Friday, May 9, 2025
5/9/2025
Continuing the development of orthopaedic surgeon-scientist expertise in patient-oriented research - ABSTRACT The overarching objective of this K24 renewal proposal is to leverage the increased protected research time afforded by the K24 award to ensure intensive mentorship of promising surgeon-scientists, sustain ongoing mentorship of surgeons within my clinical trials network, allow the completion of comparative effectiveness exploratory analyses, and develop a clinical trial master protocol. Receiving the initial K24 grant provided me with the protected time for research to achieve remarkable success in all four K24 objectives in the previous award period. It allowed me the opportunity to develop the research careers of medical students, residents, clinical fellows, graduate students, and early career surgeons. Additionally, I was able to focus on advancing several other personal career goals crucial for my sustained growth as a scientist. In response to the successes of the previous K24 award period and recognizing the increasing demand for mentorship from aspiring surgeon-scientists, this proposal entails a substantial augmentation of K24 protected time, from 25% to 40%. This K24 renewal application is of paramount importance to my commitment to supporting the new generation of surgeon-scientists and advancing the field of fracture care research. This proposal aims to strengthen my mentorship capabilities and generate novel avenues for my mentees to succeed in bolstering their independent research careers. Specifically, mentees will 1) explore clinically important research questions using high-quality data from the PREP-IT trials; 2) have immediate access to an established trial infrastructure for new ideas supported by a master protocol; and 3) develop original research ideas to be continued in their independent research careers. Over the duration of the award, I will concurrently develop my abilities as a surgeon-scientist and mentor. These career development objectives include the following: 1) increase my formal expertise in advanced research analysis techniques, and 2) expand my understanding of platform trials and master protocols. In summary, this K24 renewal proposal is designed to empower the next generation of surgeon-scientists by increasing my mentorship capacity, introducing novel research methods, and streamlining clinical trial initiation. By investing in these objectives, I aim to strengthen the foundation of fracture care research and positively impact patient care.
HHS’ Tracking Accountability in Government Grants System (TAGGS) website provides access to detailed descriptions of grants, loans, aggregated direct payments and other types of financial assistance awarded by the HHS Operating Divisions (OPDIVs) and the Office of the Secretary Staff Divisions (STAFFDIVs).