Sunday, May 11, 2025 5/11/2025

Radiographic markers of clinical function in Cervical Spondylotic Myelopathy

Award Number: K23NS091430
ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

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Radiographic markers of clinical function in Cervical Spondylotic Myelopathy - Project Summary Cervical spondylotic myelopathy (CSM) is a common degenerative condition of the cervical spine that leads to pain and progressive spinal injury. Primary drivers of clinical injury in CSM include forward head posture (a biomechanical process) and spinal compression (a neuromechanical process). The current proposal seeks to define clinically-relevant radiographic biomarkers, using standard X-ray and Magnetization Transfer-MRI images, to investigate the role of head posture and spinal compression in CSM patients and age-matched controls. These biomarkers will then be directly correlated to anatomically-specific tests of clinical function, including pain, disability, strength, and coordination. The long-term goal is to develop standardized radiographic values and thresholds that can be used to identify appropriate surgical candidates and predict prognosis.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = -$5,645 )
2024	2021	UNIVERSITY OF OKLAHOMA	865 RESEARCH PKWY	OKLAHOMA CITY	OK	73104	OKLAHOMA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	5	11/2/2023	SUPPLEMENT FOR EXPANSION	-$2,815
2024	2021	UNIVERSITY OF OKLAHOMA	865 RESEARCH PKWY	OKLAHOMA CITY	OK	73104	OKLAHOMA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	5	11/2/2023	NON-COMPETING CONTINUATION	-$2,830
														Subtotal = -$5,645

Issue Date FY: 2021 ( Subtotal = $357,303 )
2021	2021	UNIVERSITY OF OKLAHOMA	865 RESEARCH PKWY STE 530	OKLAHOMA CITY	OK	73104	OKLAHOMA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	005	5	9/22/2021	SUPPLEMENT FOR EXPANSION	$178,206
2021	2021	UNIVERSITY OF OKLAHOMA	865 RESEARCH PKWY STE 530	OKLAHOMA CITY	OK	73104	OKLAHOMA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	004	5	9/22/2021	NON-COMPETING CONTINUATION	$0
2021	2021	UNIVERSITY OF OKLAHOMA	865 RESEARCH PKWY STE 530	OKLAHOMA CITY	OK	73104	OKLAHOMA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	003	5	2/5/2021	NON-COMPETING CONTINUATION	$179,097
2021	2020	UNIVERSITY OF OKLAHOMA	865 RESEARCH PKWY STE 530	OKLAHOMA CITY	OK	73104	OKLAHOMA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	4	12/2/2020	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$34,923
2021	2020	UNIVERSITY OF OKLAHOMA	865 RESEARCH PKWY STE 530	OKLAHOMA CITY	OK	73104	OKLAHOMA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	002	4	2/4/2021	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2021	2019	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	3	12/2/2020	NON-COMPETING CONTINUATION	-$34,923
														Subtotal = $357,303

Issue Date FY: 2020 ( Subtotal = $179,637 )
2020	2020	UNIVERSITY OF OKLAHOMA	865 RESEARCH PKWY STE 530	OKLAHOMA CITY	OK	73104	OKLAHOMA	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	4	6/16/2020	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$179,637
2020	2019	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	3	6/16/2020	NON-COMPETING CONTINUATION	$0
														Subtotal = $179,637

Issue Date FY: 2019 ( Subtotal = $188,033 )
2019	2019	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	3	1/17/2019	NON-COMPETING CONTINUATION	$188,033
														Subtotal = $188,033

Issue Date FY: 2018 ( Subtotal = $188,406 )
2018	2018	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	001	2	5/9/2018	NON-COMPETING CONTINUATION	-$806
2018	2018	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	2	1/16/2018	NON-COMPETING CONTINUATION	$189,212
														Subtotal = $188,406

Issue Date FY: 2017 ( Subtotal = $189,498 )
2017	2017	NORTHWESTERN UNIVERSITY	633 CLARK ST	EVANSTON	IL	60208	COOK	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	1	1/31/2017	NEW	$189,498
														Subtotal = $189,498

Grand Total All Awards = $1,097,232

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Radiographic markers of clinical function in Cervical Spondylotic Myelopathy

Award Number: K23NS091430

ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

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