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Refinement and Testing of Implementation Strategies to Promote Psychotherapy Attendance for Depression among Latino/a Teens

Award Number: K23MD017279
ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/14/2022
PERIOD OF PERFORMANCE END DATE: 03/31/2027

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Refinement and Testing of Implementation Strategies to Promote Psychotherapy Attendance for Depression among Latino/a Teens - Despite experiencing a higher prevalence of depressive symptoms, Latino/a adolescents are significantly less likely to receive treatment for Major Depressive Disorder (MDD) and are more likely to drop out of psychotherapy prematurely than their non-Latino/a White peers. Research is needed to develop patient- and family-focused implementation strategies to promote Latino/a adolescents’ initiation of and retention in psychotherapy for depression. The candidate aims to identify, refine, and test a patient- and family-focused implementation strategy to target obstacles to psychotherapy attendance among Latino/a youth. In Aim 1, a national sample of Latino adolescents (n=15), parents (n=15), and healthcare providers (n=5) will participate in focus groups to identify preferred strategies to promote psychotherapy attendance. In Aim 2, a series of design thinking workshops will be carried out with a community advisory board (N=8) to refine and develop the content of the implementation strategy. Qualitative descriptive methods and rapid content analysis will be employed in aims 1 and 2. In Aim 3, the candidate will conduct a clinical trial to determine the preliminary effect of the patient- and family-focused implementation strategy on psychotherapy attendance and depressive symptoms among Latino/a adolescents (N=60) and identify facilitators and early implementation outcomes (acceptability, adoption, feasibility, and fidelity) related to the implementation of the strategy and psychotherapy among Latino/a adolescents. Latino/a adolescents diagnosed with MDD or Persistent Depressive Disorder and referred to psychotherapy will be recruited from primary care clinics in North Carolina and randomly assigned to the implementation strategy or treatment as usual group (n=30 each). Measurements will be taken at baseline, 12 weeks, and 24 weeks. Wilcoxon Two-Sample Tests will be used to compare group differences in the percent of scheduled psychotherapy visits attended at 24 weeks. Wilcoxon Signed Rank Tests will be used to determine change in the depressive symptoms from baseline to week 12, and baseline to week 24. Qualitative interviews with Latino/a adolescents, parents, and healthcare providers will be conducted to complete a multi-method evaluation of implementation process outcomes. The results of the study will lay a foundation for a full-scale R01 randomized controlled trial. The identified patient- and family-focused implementation strategy might also serve as a model for addressing behavioral health disparities among other groups of youth. During this award, the candidate will also obtain critical training in implementation science, adaptation of programs for Latino/a families, adolescent depression treatment, and clinical trial design. The proposed award will support the candidate’s long-term goal of promoting mental health among Latino/a adolescents and her transition into an independent, health disparities researcher


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $153,540 )
2026	2026	DUKE UNIVERSITY	2200 W MAIN ST	DURHAM	NC	27705	DURHAM	USA	Minority Health and Health Disparities Research	000	5	2/26/2026	NON-COMPETING CONTINUATION	$153,540
														Subtotal = $153,540

Issue Date FY: 2025 ( Subtotal = $153,540 )
2025	2025	DUKE UNIVERSITY	2200 W MAIN ST	DURHAM	NC	27705	DURHAM	USA	Minority Health and Health Disparities Research	001	4	4/17/2025	NON-COMPETING CONTINUATION	$153,540
2025	2025	DUKE UNIVERSITY	2200 W MAIN ST	DURHAM	NC	27705	DURHAM	USA	Minority Health and Health Disparities Research	002	4	9/3/2025	NON-COMPETING CONTINUATION	$0
2025	2024	DUKE UNIVERSITY	2200 W MAIN ST	DURHAM	NC	27705	DURHAM	USA	Minority Health and Health Disparities Research	000	3	3/18/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $153,540

Issue Date FY: 2024 ( Subtotal = $153,540 )
2024	2024	DUKE UNIVERSITY	2200 W MAIN ST	DURHAM	NC	27705	DURHAM	USA	Minority Health and Health Disparities Research	002	3	4/8/2024	NON-COMPETING CONTINUATION	$138,186
2024	2024	DUKE UNIVERSITY	2200 W MAIN ST	DURHAM	NC	27705	DURHAM	USA	Minority Health and Health Disparities Research	003	3	6/5/2024	NON-COMPETING CONTINUATION	$15,354
2024	2023	DUKE UNIVERSITY	2200 W MAIN ST	DURHAM	NC	27705	DURHAM	USA	Minority Health and Health Disparities Research	001	2	10/10/2023	NON-COMPETING CONTINUATION	$0
2024	2022	DUKE UNIVERSITY	2200 W MAIN ST	DURHAM	NC	27705	DURHAM	USA	Minority Health and Health Disparities Research	000	1	10/10/2023	NEW	$0
														Subtotal = $153,540

Issue Date FY: 2023 ( Subtotal = $153,540 )
2023	2023	DUKE UNIVERSITY	2200 W MAIN ST	DURHAM	NC	27705	DURHAM	USA	Minority Health and Health Disparities Research	000	2	3/11/2023	NON-COMPETING CONTINUATION	$153,540
														Subtotal = $153,540

Issue Date FY: 2022 ( Subtotal = $153,540 )
2022	2022	DUKE UNIVERSITY	2200 W MAIN ST STE 710	DURHAM	NC	27708	DURHAM	USA	Minority Health and Health Disparities Research	000	1	7/14/2022	NEW	$153,540
														Subtotal = $153,540

Grand Total All Awards = $767,700

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Refinement and Testing of Implementation Strategies to Promote Psychotherapy Attendance for Depression among Latino/a Teens

Award Number: K23MD017279

ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/14/2022

PERIOD OF PERFORMANCE END DATE: 03/31/2027

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