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 | Issue Date FY: 2025 ( Subtotal = $225,272,994 ) (Continued on the next page) |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA276089 | Manipulating normal estrogen physiology as a therapeutic approach in cancer | 001 | 3 | NIH | 5/29/2025 | $54,200 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA276089 | Manipulating normal estrogen physiology as a therapeutic approach in cancer | 000 | 3 | NIH | 1/13/2025 | $487,802 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R35GM144042 | Computational and Experimental Studies of Protein Structure and Design | 001 | 4 | NIH | 1/16/2025 | $523,726 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01GM118447 | Polyploidy after tissue injury: a Drosophila model | 000 | 9 | NIH | 12/11/2024 | $287,731 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01EY026885 | Autophagy and Mechanotransduction in the Trabecular Meshwork | 000 | 9 | NIH | 11/27/2024 | $450,475 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | UG1HD112063 | Duke University Maternal-Fetal Medicine Units (MFMU) Network Clinical Center | 000 | 3 | NIH | 3/28/2025 | $335,838 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA280970 | Next-generation SMARTs for Discovery and Evaluation of Sequential Cancer Therapeutic Strategies | 001 | 2 | NIH | 5/29/2025 | $35,470 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA280970 | Next-generation SMARTs for Discovery and Evaluation of Sequential Cancer Therapeutic Strategies | 000 | 2 | NIH | 11/26/2024 | $319,220 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01ES034270 | Which mechanisms of pollutant-induced mitochondrial dysfunction cause dopaminergic neurodegeneration? | 000 | 3 | NIH | 11/4/2024 | $400,684 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA269211 | Targeting Ferroptosis in Lethal RB1 Deficient Prostate Cancer | 000 | 4 | NIH | 3/12/2025 | $378,126 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01MH131667 | Bridging Scales to Understand Endogenous Neuromodulation and its Regulation | 000 | 3 | NIH | 3/19/2025 | $488,365 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AR079235 | Targeting PTEN to ameliorate muscular dystrophy in a mouse model | 004 | 4 | NIH | 6/10/2025 | $554,822 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AR079235 | Targeting PTEN to ameliorate muscular dystrophy in a mouse model | 001 | 4 | NIH | 3/20/2025 | $319,770 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AR079184 | Biomechanical and Biological Predictors of Cartilage Health Following Meniscus Injury | 002 | 5 | NIH | 5/9/2025 | $46,085 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AR079184 | Biomechanical and Biological Predictors of Cartilage Health Following Meniscus Injury | 000 | 5 | NIH | 3/20/2025 | $592,521 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01MH125236 | Beyond GWAS: High Throughput Functional Genomics & Epigenome Editing to Elucidate the Effects of Genetic Associations for Schizophrenia | 000 | 5 | NIH | 3/18/2025 | $1,359,313 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K23HL155500 | Developing an intervention to improve quality of myocardial infarction care in northern Tanzania | 000 | 5 | NIH | 2/27/2025 | $166,860 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F32AG077907 | Understanding the Mechanisms and Consequences of Basement Membrane Aging in Vivo | 000 | 3 | NIH | 3/6/2025 | $78,892 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U01AA029969 | 5/11 Microglial MyD88 in Mouse Models of Excessive Alcohol Intake | 000 | 4 | NIH | 3/4/2025 | $354,555 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K01DK135793 | Targeting Hepatocyte Senescence to Improve NAFLD | 000 | 2 | NIH | 3/19/2025 | $143,747 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AI175411 | Overcoming humoral rejection after xenotransplantation in sensitized nonhuman primate recipients | 000 | 3 | NIH | 2/12/2025 | $762,292 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01EY025009 | Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care | 000 | 9 | NIH | 3/14/2025 | $584,528 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DC022619 | Dynamics of Olfactory Processing: Segmentation in the Piriform Cortex | 000 | 1 | NIH | 3/18/2025 | $502,742 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AR079189 | Modulation of local adenosine signaling to attenuate fracture pain | 002 | 5 | NIH | 5/9/2025 | $38,130 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01MH128422 | NeuroSimNIBS: Integrated electric field and neuronal response modeling for transcranial electric and magnetic stimulation | 000 | 4 | NIH | 3/11/2025 | $450,776 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AR079189 | Modulation of local adenosine signaling to attenuate fracture pain | 000 | 5 | NIH | 3/17/2025 | $490,244 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F31DA057116 | Epigenetic Regulation of Microglia Dopamine System Interactions | 000 | 3 | NIH | 3/17/2025 | $41,559 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DK132819 | Metabolic regulation of muscle satellite cell homeostasis | 002 | 3 | NIH | 6/12/2025 | $52,201 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DK132819 | Metabolic regulation of muscle satellite cell homeostasis | 001 | 3 | NIH | 3/3/2025 | $479,546 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F31EY035522 | Assessing the spatial and temporal scales of attention effects and attention-dependent cholinergic release in macque V4. | 000 | 2 | NIH | 3/20/2025 | $41,749 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01MD018920 | SER Familia: A Family-Based Intervention Addressing Syndemic Conditions among Latino Immigrant Families | 000 | 2 | NIH | 2/18/2025 | $525,335 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01NS129112 | Information Preservation in Neural Codes | 000 | 4 | NIH | 3/7/2025 | $493,741 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AG073994 | Use of C. elegans as a model to study aging-associated neurodegeneration | 000 | 4 | NIH | 3/11/2025 | $443,941 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01NS129617 | A Risk Stratification Model for Health and Academic Outcomes in Children with Concussion Based on Novel Symptom Trajectory Typologies | 000 | 3 | NIH | 3/12/2025 | $554,454 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01NS140419 | Pathogenic Mechanisms of Inflammatory Subventricular Zone Injury in Preterm Infants | 000 | 1 | NIH | 3/13/2025 | $635,386 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01EY030611 | Mechanisms of naturally-occurring astrocyte death during retinal development | 000 | 6 | NIH | 3/13/2025 | $392,151 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R25HD094667 | UrogynCREST Program | 002 | 7 | NIH | 4/2/2025 | $157,912 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DA055414 | Microglial pruning of dopamine receptors and opioid abuse. | 001 | 4 | NIH | 4/10/2025 | $38,451 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DA055414 | Microglial pruning of dopamine receptors and opioid abuse. | 000 | 4 | NIH | 2/27/2025 | $346,060 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AR079572 | Gene therapy for glycogen storage disease type III | 001 | 4 | NIH | 5/8/2025 | $46,448 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K23MD017279 | Refinement and Testing of Implementation Strategies to Promote Psychotherapy Attendance for Depression among Latinx Teens | 001 | 4 | NIH | 4/17/2025 | $153,540 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AR079572 | Gene therapy for glycogen storage disease type III | 000 | 4 | NIH | 3/20/2025 | $597,162 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01HL161071 | Red blood cell ATP export and transfusion in sepsis | 000 | 3 | NIH | 2/19/2025 | $609,442 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01HL161071 | Red blood cell ATP export and transfusion in sepsis | 001 | 3 | NIH | 4/25/2025 | $0 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA251439 | Targeting ATM to boost systemic effects of radiotherapy and immunotherapy | 001 | 5 | NIH | 5/22/2025 | $52,656 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA251439 | Targeting ATM to boost systemic effects of radiotherapy and immunotherapy | 000 | 5 | NIH | 2/18/2025 | $473,907 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DE025994 | Defining the Mechanisms of Epstein-Barr Virus Persistence and Recurrence | 001 | 10 | NIH | 5/7/2025 | $46,707 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DE025994 | Defining the Mechanisms of Epstein-Barr Virus Persistence and Recurrence | 000 | 10 | NIH | 3/7/2025 | $420,370 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K01AR082432 | Mechanism of epidermal coordination during development and regeneration in zebrafish | 000 | 3 | NIH | 3/6/2025 | $104,029 |
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