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 | Issue Date FY: 2025 ( Subtotal = $163,134,802 ) (Continued on the next page) |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AG081774 | Hypoperfusion, Hemodynamic Control Domains and Neurovascular Dysregulation in AD brain pathology | 000 | 3 | NIH | 3/11/2025 | $415,261 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F32CA298007 | The Role of SMARCAL1 Depletion on Increased Immunogenicity in ALT+ Gliomas | 000 | 1 | NIH | 3/10/2025 | $73,828 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F32CA298007 | The Role of SMARCAL1 Depletion on Increased Immunogenicity in ALT+ Gliomas | 001 | 1 | NIH | 3/10/2025 | $0 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F32CA298657 | Manipulating Sex Hormone Signaling for Therapeutic Benefit in Liver Cancer | 001 | 1 | NIH | 3/10/2025 | $0 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R21HD118539 | The Health Consequences of Childhood Maltreatment and Foster Care From Adolescence Into Mid-Life | 000 | 1 | NIH | 2/24/2025 | $235,564 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F32CA298657 | Manipulating Sex Hormone Signaling for Therapeutic Benefit in Liver Cancer | 000 | 1 | NIH | 3/10/2025 | $81,364 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01NS129112 | Information Preservation in Neural Codes | 000 | 4 | NIH | 3/7/2025 | $493,741 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AG073994 | Use of C. elegans as a model to study aging-associated neurodegeneration | 000 | 4 | NIH | 3/11/2025 | $443,941 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01MD018920 | SER Familia: A Family-Based Intervention Addressing Syndemic Conditions among Latino Immigrant Families | 000 | 2 | NIH | 2/18/2025 | $525,335 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F31AR082701 | The role(s) of muscle resident fibro-adipogenic progenitor cells in massive rotator cuff tear pathologies. | 000 | 2 | NIH | 3/13/2025 | $41,893 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K08DK136924 | Identification of Host-Specific Determinants of APOL1-associated COVAN | 000 | 2 | NIH | 2/26/2025 | $153,306 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01GM148770 | Chemical Biology of the E3 Ubiqutin Ligase Nedd4 | 000 | 3 | NIH | 2/21/2025 | $285,122 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | UH3NS129898 | An Integrated Biomarker Approach to Personalized, Adaptive Deep Brain Stimulation in Parkinson Disease | 000 | 3 | NIH | 1/27/2025 | $910,776 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K01AG070284 | Supporting Patients and Family Care Partners to Manage Chronic Kidney Disease Together | 000 | 5 | NIH | 1/29/2025 | $108,310 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01NS121067 | Treatment of Primary Amoebic Meningoencephalitis via Modulation of Antibody Effector Functions | 000 | 5 | NIH | 1/27/2025 | $362,250 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R21HD112673 | Developmental Origins of the Sturge Weber Syndrome Somatic Mutation | 000 | 1 | NIH | 1/28/2025 | $201,875 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01HL177642 | Alveolar injury and repair in Pompe Disease | 000 | 1 | NIH | 1/29/2025 | $762,974 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AG072732 | Retinal Light Scattering Measurements as a Clinical Biomarker of Alzheimer's Disease | 000 | 4 | NIH | 1/30/2025 | $442,439 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01EY035637 | Molecular and cellular requirements for Crb1 gene function in the onset and therapeutic rescue of an inherited retinal degeneration | 000 | 2 | NIH | 11/26/2024 | $511,878 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K23MD018433 | Equity Focused Communication Intervention for Family-Centered Rounds | 001 | 2 | NIH | 4/24/2025 | $16,140 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K23MD018433 | Equity Focused Communication Intervention for Family-Centered Rounds | 000 | 2 | NIH | 1/19/2025 | $145,265 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA276089 | Manipulating normal estrogen physiology as a therapeutic approach in cancer | 000 | 3 | NIH | 1/13/2025 | $487,802 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01GM118447 | Polyploidy after tissue injury: a Drosophila model | 000 | 9 | NIH | 12/11/2024 | $287,731 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01EY026885 | Autophagy and Mechanotransduction in the Trabecular Meshwork | 000 | 9 | NIH | 11/27/2024 | $450,475 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R35GM144042 | Computational and Experimental Studies of Protein Structure and Design | 001 | 4 | NIH | 1/16/2025 | $523,726 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U01AI162463 | Improving Neonatal health Through Rapid malaria testing in Early Pregnancy with high-sensitivity Diagnostics (INTREPiD) | 000 | 4 | NIH | 3/21/2025 | $1,453,036 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R25HD094667 | UrogynCREST Program | 002 | 7 | NIH | 4/2/2025 | $157,912 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AI125517 | Genetic dissection of angiogenesis during mycobacterial infection | 000 | 9 | NIH | 2/13/2025 | $464,756 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DK129488 | Novel roles of PDK4 in regulating mitochondrial protein phosphorylation, carbon flux and metabolic resilience | 000 | 4 | NIH | 2/18/2025 | $571,434 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | T32AI141342 | Advanced Immunobiology Traning Program for Surgeons | 002 | 7 | NIH | 4/8/2025 | $277,666 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA269211 | Targeting Ferroptosis in Lethal RB1 Deficient Prostate Cancer | 000 | 4 | NIH | 3/12/2025 | $378,126 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AR079235 | Targeting PTEN to ameliorate muscular dystrophy in a mouse model | 001 | 4 | NIH | 3/20/2025 | $319,770 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01MH131667 | Bridging Scales to Understand Endogenous Neuromodulation and its Regulation | 000 | 3 | NIH | 3/19/2025 | $488,365 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AR079184 | Biomechanical and Biological Predictors of Cartilage Health Following Meniscus Injury | 000 | 5 | NIH | 3/20/2025 | $592,521 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DC022619 | Dynamics of Olfactory Processing: Segmentation in the Piriform Cortex | 000 | 1 | NIH | 3/18/2025 | $502,742 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AR079189 | Modulation of local adenosine signaling to attenuate fracture pain | 000 | 5 | NIH | 3/17/2025 | $490,244 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01MH128422 | NeuroSimNIBS: Integrated electric field and neuronal response modeling for transcranial electric and magnetic stimulation | 000 | 4 | NIH | 3/11/2025 | $450,776 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F31DA057116 | Epigenetic Regulation of Microglia Dopamine System Interactions | 000 | 3 | NIH | 3/17/2025 | $41,559 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01MH125236 | Beyond GWAS: High Throughput Functional Genomics & Epigenome Editing to Elucidate the Effects of Genetic Associations for Schizophrenia | 000 | 5 | NIH | 3/18/2025 | $1,359,313 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K23HL155500 | Developing an intervention to improve quality of myocardial infarction care in northern Tanzania | 000 | 5 | NIH | 2/27/2025 | $166,860 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F32AG077907 | Understanding the Mechanisms and Consequences of Basement Membrane Aging in Vivo | 000 | 3 | NIH | 3/6/2025 | $78,892 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DK046492 | Engineered Glucose Metabolism in Insulin Secreting Cells | 000 | 30 | NIH | 2/18/2025 | $565,197 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K01DK135793 | Targeting Hepatocyte Senescence to Improve NAFLD | 000 | 2 | NIH | 3/19/2025 | $143,747 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AI175411 | Overcoming humoral rejection after xenotransplantation in sensitized nonhuman primate recipients | 000 | 3 | NIH | 2/12/2025 | $762,292 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01EY025009 | Analyzing Retinal Microanatomy in Retinopathy of Prematurity to Improve Care | 000 | 9 | NIH | 3/14/2025 | $584,528 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01HL161071 | Red blood cell ATP export and transfusion in sepsis | 001 | 3 | NIH | 4/25/2025 | $0 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01HL161071 | Red blood cell ATP export and transfusion in sepsis | 000 | 3 | NIH | 2/19/2025 | $609,442 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K23MD017279 | Refinement and Testing of Implementation Strategies to Promote Psychotherapy Attendance for Depression among Latinx Teens | 001 | 4 | NIH | 4/17/2025 | $153,540 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DE025994 | Defining the Mechanisms of Epstein-Barr Virus Persistence and Recurrence | 000 | 10 | NIH | 3/7/2025 | $420,370 |
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