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 | Issue Date FY: 2022 ( Subtotal = $628,903,912 ) (Continued on the next page) |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | A2230993 | Nurse Anesthetist Traineeships | 00 | 6 | HRSA | 5/23/2022 | $31,034 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R33HL138650 | Randomized Trial of Endotracheal Tubes to Prevent Ventilator-Associated Pneumonia - Prevent 2 Study | 001 | 5 | NIH | 9/19/2022 | $743,776 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01HL142286 | Regulation of Vascular Inflammatory Signaling by the Deubiquitinase USP20 | 001 | 4 | NIH | 5/31/2022 | $53,461 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01HL142286 | Regulation of Vascular Inflammatory Signaling by the Deubiquitinase USP20 | 000 | 4 | NIH | 1/31/2022 | $481,165 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01AI139216 | Discovery and validation of broadly effective LpxH inhibitors as novel therapeutics against multi-drug resistant Gram-negative pathogens | 000 | 4 | NIH | 2/1/2022 | $458,280 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01CA242593 | A Text-Based Scheduled Reduction Intervention for Smokeless Tobacco Cessation | 000 | 4 | NIH | 9/12/2022 | $368,288 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01HL147157 | Anti-Atherogenic Mechanisms of Drebrin | 001 | 3 | NIH | 6/8/2022 | $52,324 |
| | 2022 | 2022 | Duke University | 2200 W Main St Ste 710 | Durham | NC | 27708-4677 | DURHAM | USA | NU50DD000054 | The North Carolina Congenital Heart Disease Surveillance Network | 01 | 4 | CDC | 6/24/2022 | $0 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01CA249959 | Persistent Post-Mastectomy Pain: Randomized Clinical Trial of Targeted Pain Coping Skills Training (Targeted-PCST) with Mediational Analysis | 000 | 3 | NIH | 4/11/2022 | $633,073 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01AG062502 | Functional Limitations and Disability Among Middle-Aged Adults | 001 | 3 | NIH | 5/2/2022 | $45,744 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01AG062502 | Functional Limitations and Disability Among Middle-Aged Adults | 000 | 3 | NIH | 12/17/2021 | $411,682 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01HL147157 | Anti-Atherogenic Mechanisms of Drebrin | 000 | 3 | NIH | 11/29/2021 | $470,926 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | NU50DD000054 | The North Carolina Congenital Heart Disease Surveillance Network | 00 | 4 | CDC | 5/26/2022 | $400,000 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R37CA249085 | Investigating the PD-L1:NLRP3 signaling axis as a tumor intrinsic mechanism of adaptive resistance to anti-PD-1 antibody immunotherapy | 001 | 3 | NIH | 7/25/2022 | $132,629 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R37CA249085 | Investigating the PD-L1:NLRP3 signaling axis as a tumor intrinsic mechanism of adaptive resistance to anti-PD-1 antibody immunotherapy | 000 | 3 | NIH | 7/22/2022 | $320,179 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01TW011493 | The Impact of Land Use Change on Transmission Potential Networks and Disease Spread in Rural Madagascar | 004 | 4 | NIH | 9/13/2022 | $18,708 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01TW011493 | The Impact of Land Use Change on Transmission Potential Networks and Disease Spread in Rural Madagascar | 003 | 4 | NIH | 9/13/2022 | $75,792 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01TW011493 | The Impact of Land Use Change on Transmission Potential Networks and Disease Spread in Rural Madagascar | 002 | 4 | NIH | 9/7/2022 | $75,792 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01CA234348 | Dissecting the role of EBV and P. falciparum in endemic Burkitt lymphoma pathogenesis | 000 | 4 | NIH | 7/26/2022 | $640,406 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01TW011493 | The Impact of Land Use Change on Transmission Potential Networks and Disease Spread in Rural Madagascar | 001 | 4 | NIH | 4/14/2022 | $456,622 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01NS111588 | Metabolic regulation of KLHL proteins through O-glycosylation | 000 | 4 | NIH | 3/24/2022 | $526,958 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01CA244564 | Synthetic lethality by targeting the core senescent mechanism in lung cancer. | 001 | 3 | NIH | 6/9/2022 | $39,259 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01CA244564 | Synthetic lethality by targeting the core senescent mechanism in lung cancer. | 000 | 3 | NIH | 1/31/2022 | $441,648 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | K00CA245732 | Uncovering actionable signaling pathways required for solid tumor brain metastasis | 000 | 4 | NIH | 6/23/2022 | $88,956 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | F31MH124422 | Elucidating mechanisms underlying fluctuations of sustained attention and their influence on memory | 000 | 3 | NIH | 5/31/2022 | $46,753 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01NS110552 | Mechanisms of Disease associated with mechanically-activated Piezo ion channels | 001 | 3 | NIH | 3/24/2022 | $37,425 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | K24AI143971 | Mentoring in Clinical Pharmacology and Early Phase Trials | 000 | 4 | NIH | 5/11/2022 | $177,687 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01DK123097 | Targeting Renal Tubular Epithelial Progenitors in AKI to CKD transition | 000 | 3 | NIH | 6/29/2022 | $438,195 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01NS110552 | Mechanisms of Disease associated with mechanically-activated Piezo ion channels | 000 | 3 | NIH | 1/5/2022 | $336,823 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R34MH128440 | Sustainable Habits for Encouraging Even Teen Sleep (SHEETS): A Digital Intervention to Enhance Sleep Regularity and Psychiatric Health in Adolescents | 000 | 1 | NIH | 1/17/2022 | $281,750 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01EY021798 | Defining the Immune Cell Roles in Meibomian Gland Dysfunction in the Context of Ocular Surface Immune Diseases | 000 | 11 | NIH | 9/20/2022 | $398,756 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01HL160697 | Oxidative stress mechanisms regulating gamma-globin gene transcription in sickle cell disease | 000 | 1 | NIH | 6/17/2022 | $610,202 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01CA271129 | Clinical evaluation and non-invasive monitoring of Vorasidenib in combination with tumor specific peptide PEP-IDH1M vaccine therapy in patients with recurrent mutant IDH1 glioma | 000 | 1 | NIH | 9/21/2022 | $392,725 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01AI170543 | RNAi-dependent epimutation roles in antimicrobial drug resistance and pathogenesis | 000 | 1 | NIH | 6/28/2022 | $714,221 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R21AI167242 | Longitudinal cohort study of SARS-CoV2 sero-conversion in a malaria-endemic community in Western Kenya | 000 | 1 | NIH | 12/10/2021 | $243,050 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R21HD107249 | Net Worth Poverty and Children's Development | 000 | 1 | NIH | 8/3/2022 | $241,500 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01GM146010 | Social experience dependent modification of gene regulation and circuit function | 000 | 1 | NIH | 6/15/2022 | $315,188 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R25DC020172 | Otolaryngology Surgeon- Scientist career Path (OSSP) program | 000 | 1 | NIH | 3/25/2022 | $182,792 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R61MH127137 | FlexED: A Digital, Gamified Early Intervention for Eating Disorders | 000 | 1 | NIH | 9/14/2022 | $967,928 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01CA224434 | GMPS-GMPR Axis Melanoma Progression and Therapy | 001 | 6 | NIH | 8/1/2022 | $392,357 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01HL142985 | Loss of cellular identity after influenza virus infection and effects on pulmonary function | 000 | 5 | NIH | 6/20/2022 | $588,098 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01DA047115 | Psychostimulant-Induced Plasticity of Nucleus Accumbens Interneurons | 001 | 4 | NIH | 3/25/2022 | $45,077 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01DA047115 | Psychostimulant-Induced Plasticity of Nucleus Accumbens Interneurons | 000 | 4 | NIH | 1/13/2022 | $405,683 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | H79TI085224 | EASE (Enhancing Wellness through Affirming Services and Education) | 000 | 1 | SAMHSA | 9/15/2022 | $500,000 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01EY034134 | Elucidating perifoveal vascular development in infants | 000 | 1 | NIH | 9/2/2022 | $414,256 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R21AG074317 | Protein Stability Profiling for the Characterization of Alzheimer's Disease | 000 | 1 | NIH | 7/28/2022 | $423,898 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01HD106588 | Digoxin Pharmacodynamics in Infants with Heart Failure due to Single Ventricle Congenital Heart Disease | 000 | 1 | NIH | 4/2/2022 | $649,188 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01MH126954 | Proteomic and Functional Analysis of Presynaptic Physiology and Plasticity | 001 | 2 | NIH | 6/21/2022 | $54,085 |
| | 2022 | 2022 | DUKE UNIVERSITY | 2200 W MAIN ST STE 710 | DURHAM | NC | 27708-4677 | DURHAM | USA | R01MH126954 | Proteomic and Functional Analysis of Presynaptic Physiology and Plasticity | 000 | 2 | NIH | 3/14/2022 | $486,751 |
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