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 | Issue Date FY: 2025 ( Subtotal = $111,009,162 ) (Continued on the next page) |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U01AG084765 | Skin immunity as a function of frailty, aging, and skin microbiome composition | 002 | 2 | NIH | 3/19/2025 | $441,532 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F32HD118698 | Understanding the role of mitochondrial specialization in early development | 000 | 1 | NIH | 3/20/2025 | $74,284 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01MH131667 | Bridging Scales to Understand Endogenous Neuromodulation and its Regulation | 000 | 3 | NIH | 3/19/2025 | $488,365 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K01DK135793 | Targeting Hepatocyte Senescence to Improve NAFLD | 000 | 2 | NIH | 3/19/2025 | $143,747 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R21AI187688 | Inducing Xenotolerance via Chimeric Thymus | 000 | 1 | NIH | 11/14/2024 | $195,819 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U19AI160546 | Conjugate nanoparticle platform development for HIV-1 envelope immunogens | 001 | 4 | NIH | 2/12/2025 | $0 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AI125045 | Preclinical studies of a Cryptococcus vaccine for AIDS patients | 000 | 11 | NIH | 1/9/2025 | $769,284 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R21HD118539 | The Health Consequences of Childhood Maltreatment and Foster Care From Adolescence Into Mid-Life | 000 | 1 | NIH | 2/24/2025 | $235,564 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DK129488 | Novel roles of PDK4 in regulating mitochondrial protein phosphorylation, carbon flux and metabolic resilience | 000 | 4 | NIH | 2/18/2025 | $571,434 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F32HD117597 | Investigating the role of gene regulatory networks in neonatal nutrition and immunity | 004 | 1 | NIH | 1/15/2025 | $0 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F32AG077907 | Understanding the Mechanisms and Consequences of Basement Membrane Aging in Vivo | 000 | 3 | NIH | 3/6/2025 | $78,892 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F32HD117597 | Investigating the role of gene regulatory networks in neonatal nutrition and immunity | 003 | 1 | NIH | 1/15/2025 | $0 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA251407 | Targeting the metastasis initiating cell in undifferentiated pleomorphic sarcoma | 000 | 5 | NIH | 3/27/2025 | $403,648 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA246133 | Targeting tumor-neural cell interactions to inhibit lung cancer brain metastasis | 000 | 5 | NIH | 3/27/2025 | $374,862 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K08DK136924 | Identification of Host-Specific Determinants of APOL1-associated COVAN | 000 | 2 | NIH | 2/26/2025 | $153,306 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DA055414 | Microglial pruning of dopamine receptors and opioid abuse. | 000 | 4 | NIH | 2/27/2025 | $346,060 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F32CA298657 | Manipulating Sex Hormone Signaling for Therapeutic Benefit in Liver Cancer | 001 | 1 | NIH | 3/10/2025 | $0 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | D43TW012457 | Building Brain Health Research Capacity in Rwanda: Neurocognition and Neurobehavior Across the Lifespan | 000 | 2 | NIH | 2/26/2025 | $145,424 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | D43TW012457 | Building Brain Health Research Capacity in Rwanda: Neurocognition and Neurobehavior Across the Lifespan | 000 | 2 | NIH | 2/26/2025 | $100,000 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01HL161071 | Red blood cell ATP export and transfusion in sepsis | 000 | 3 | NIH | 2/19/2025 | $609,442 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01GM150666 | Investigating mechanisms of cell volume regulation in the zebrafish notochord | 000 | 2 | NIH | 2/20/2025 | $393,906 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K23HL155500 | Developing an intervention to improve quality of myocardial infarction care in northern Tanzania | 000 | 5 | NIH | 2/27/2025 | $166,860 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K01AI175527 | Synthesizing immunoinformatics and genetic epidemiology to identify signatures of natural functional immunity to malaria parasites | 000 | 3 | NIH | 3/22/2025 | $120,065 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01EY035525 | Molecular mechanisms of photoreceptor disc morphogenesis | 000 | 3 | NIH | 3/14/2025 | $648,451 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AG081774 | Hypoperfusion, Hemodynamic Control Domains and Neurovascular Dysregulation in AD brain pathology | 000 | 3 | NIH | 3/11/2025 | $415,261 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AG076903 | APOE4 dependent regulation of CSF Complement Pathway Activation in the development of Alzheimer's Disease | 001 | 4 | NIH | 3/25/2025 | $682,453 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R21EY036170 | Measuring Ocular Pulse Amplitude with Fixed Force Applanation on Normotensive and Hypertensive Eyes | 000 | 1 | NIH | 2/21/2025 | $245,243 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AG074999 | Extracranial Brain Stimulation Reduces Metabolic Insufficiency Through Enhanced Cerebral Blood Flow in CVN-AD Alzheimer's Model | 000 | 4 | NIH | 3/4/2025 | $326,025 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA269272 | Genetic dissection of oncogenic RAS-driven tumor initiation in vivo | 000 | 4 | NIH | 3/10/2025 | $397,893 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA271589 | Genetic Origins of Adverse Outcomes in African Americans with Lymphoma | 000 | 3 | NIH | 3/4/2025 | $437,123 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F32CA298007 | The Role of SMARCAL1 Depletion on Increased Immunogenicity in ALT+ Gliomas | 000 | 1 | NIH | 3/10/2025 | $73,828 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F32CA298657 | Manipulating Sex Hormone Signaling for Therapeutic Benefit in Liver Cancer | 000 | 1 | NIH | 3/10/2025 | $81,364 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA290724 | Cellular basis for cancer treatment related GDF15 expression and the regulation of skeletal muscle fibrosis and neuromuscular integrity. | 000 | 2 | NIH | 3/10/2025 | $378,075 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA262134 | NEUROD1 function in SCLC fate and plasticity | 000 | 2 | NIH | 3/3/2025 | $481,566 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DK132819 | Metabolic regulation of muscle satellite cell homeostasis | 001 | 3 | NIH | 3/3/2025 | $479,546 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA261949 | Engineering Large Chromosomal Deletions in Mice to Advance Precision Oncology | 000 | 4 | NIH | 3/4/2025 | $374,887 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R00EY033027 | Development of a program to assess and treat distress in glaucoma patients using an automated EHR-derived AI algorithm | 000 | 4 | NIH | 3/21/2025 | $242,331 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | UG1EY033287 | NAC Attack, a phase-3, multicenter, randomized, placebo-controlled trial with retinitis pigmentosa: OCT Reading Center | 000 | 4 | NIH | 3/21/2025 | $256,633 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U01AI162463 | Improving Neonatal health Through Rapid malaria testing in Early Pregnancy with high-sensitivity Diagnostics (INTREPiD) | 000 | 4 | NIH | 3/21/2025 | $1,453,036 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01GM148770 | Chemical Biology of the E3 Ubiqutin Ligase Nedd4 | 000 | 3 | NIH | 2/21/2025 | $285,122 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AI130236 | Macrophage Reprogramming During Granuloma Formation in the Zebrafish | 000 | 9 | NIH | 2/21/2025 | $464,284 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AG073994 | Use of C. elegans as a model to study aging-associated neurodegeneration | 000 | 4 | NIH | 3/11/2025 | $443,941 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DK132070 | Bacteria sensory transduction from gut to brain to modulate behavior | 000 | 3 | NIH | 2/17/2025 | $409,557 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA251439 | Targeting ATM to boost systemic effects of radiotherapy and immunotherapy | 000 | 5 | NIH | 2/18/2025 | $473,907 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K01HS028529 | Evaluating the Implementation of High Intensity Home-Based Rehabilitation Following Stroke | 000 | 5 | AHRQ | 3/21/2025 | $144,936 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01TW012673 | Designing an Ethnodrama Intervention Addressing PrEP Stigma Toward Young Women | 000 | 3 | NIH | 3/21/2025 | $157,620 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01MH126954 | Proteomic and Functional Analysis of Presynaptic Physiology and Plasticity | 000 | 5 | NIH | 3/21/2025 | $503,562 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DK046492 | Engineered Glucose Metabolism in Insulin Secreting Cells | 000 | 30 | NIH | 2/18/2025 | $565,197 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | UG1CA233253 | NCI National Clinical Trials Network (UG1) | 002 | 6 | NIH | 3/21/2025 | $259,447 |
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