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 | Issue Date FY: 2025 ( Subtotal = $609,394,891 ) (Continued on the next page) |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01HL161071 | Red blood cell ATP export and transfusion in sepsis | 000 | 3 | NIH | 2/19/2025 | $609,442 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K12TR005435 | CTSA K12 Program at Duke University | 000 | 1 | NIH | 8/14/2025 | $1,577,781 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U01AI192382 | Mechanisms of Early-life Immunity Associated with HIV-1 Vaccine-induced Neutralizing Antibody Responses | 000 | 1 | NIH | 8/20/2025 | $1,239,565 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DE025994 | Defining the Mechanisms of Epstein-Barr Virus Persistence and Recurrence | 001 | 10 | NIH | 5/7/2025 | $46,707 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DE025994 | Defining the Mechanisms of Epstein-Barr Virus Persistence and Recurrence | 000 | 10 | NIH | 3/7/2025 | $420,370 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K01AR082432 | Mechanism of epidermal coordination during development and regeneration in zebrafish | 000 | 3 | NIH | 3/6/2025 | $104,029 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R00AR080218 | "Lnc"ing XIST Ribonucleoprotein Particles to Female Sex-Attributed Biases in Autoimmunity | 001 | 3 | NIH | 8/21/2025 | -$249,000 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U01EY037666 | Academic/Industry Partnership for Next-Generation Robotically Guided Intraoperative Ophthalmic OCT | 001 | 1 | NIH | 9/22/2025 | $15,375 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R00AR080218 | "Lnc"ing XIST Ribonucleoprotein Particles to Female Sex-Attributed Biases in Autoimmunity | 001 | 3 | NIH | 8/21/2025 | $249,000 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U01EY037666 | Academic/Industry Partnership for Next-Generation Robotically Guided Intraoperative Ophthalmic OCT | 000 | 1 | NIH | 8/15/2025 | $776,619 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R00AR080218 | "Lnc"ing XIST Ribonucleoprotein Particles to Female Sex-Attributed Biases in Autoimmunity | 000 | 3 | NIH | 8/14/2025 | $249,000 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U01EY034687 | Blink, Lacrimation, and Nociception: Precision Mapping and Integrated Atlas Generation of Corneal Trigeminal Afferents | 000 | 4 | NIH | 9/19/2025 | $1,105,585 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R33NS133213 | Small molecule inhibitors of TrkB Signaling | 000 | 3 | NIH | 8/20/2025 | $341,997 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01NS140419 | Pathogenic Mechanisms of Inflammatory Subventricular Zone Injury in Preterm Infants | 000 | 1 | NIH | 3/13/2025 | $635,386 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01EY037682 | Gene therapy targeting CFH and lipoprotein dynamics in AMD | 000 | 1 | NIH | 8/18/2025 | $675,193 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K08HL181178 | The Post-Lung Transplant Impact of Alveolar Macrophage Senescence in Aged Donor Lungs | 000 | 1 | NIH | 9/1/2025 | $158,652 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | F31AI186495 | Malaria & Migration: Assessing Local Malaria Change near Migrant Communities in Panama | 000 | 1 | NIH | 9/23/2025 | $49,538 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01EY030611 | Mechanisms of naturally-occurring astrocyte death during retinal development | 000 | 6 | NIH | 3/13/2025 | $392,151 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U01AI195193 | Combating Related Epidemics in HCV through Simplified Testing and Treatment (CREST) | 000 | 1 | NIH | 9/24/2025 | $3,411,692 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K23AI177941 | Role of C difficile Colonization in Risk of Disease | 000 | 1 | NIH | 8/8/2025 | $184,651 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | DP1DA063507 | Dissecting and modulating cell type and circuit-specific epigenetic mechanisms of cocaine addiction | 000 | 1 | NIH | 9/25/2025 | $436,050 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K23HL177307 | Proteomic profiling for proteins associated with intracranial atherosclerotic disease. | 000 | 1 | NIH | 8/18/2025 | $158,910 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AR085059 | Deconstructing the molecular and cellular mechanisms of psoriatic arthritis pain by an improved animal model | 000 | 1 | NIH | 8/14/2025 | $1,617,503 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AI186386 | Developing a bioprinted ventilated lung alveolar platform for investigating microbial interactions and influenza response | 000 | 1 | NIH | 8/19/2025 | $3,182,827 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K08HL181195 | Role of Protein S-Palmitoylation in TGFbeta Signaling and Fibrotic Lung Disease | 000 | 1 | NIH | 8/14/2025 | $165,456 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U01AI189426 | Serum pro-N-cadherin as an early biomarker of radiation-induced heart disease | 000 | 1 | NIH | 8/6/2025 | $565,250 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R21EB036580 | Developing Hyperpolarized Nitrogen-15 MRI Agents for Probing Glutamine Metabolism | 000 | 1 | NIH | 7/7/2025 | $212,408 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K23DA063795 | Harm Reduction Behavior Therapy for Post-Incarceration Drug Use in Enhanced Reentry Primary Care | 000 | 1 | NIH | 8/19/2025 | $181,681 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA251439 | Targeting ATM to boost systemic effects of radiotherapy and immunotherapy | 001 | 5 | NIH | 5/22/2025 | $52,656 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01CA251439 | Targeting ATM to boost systemic effects of radiotherapy and immunotherapy | 000 | 5 | NIH | 2/18/2025 | $473,907 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01NS129617 | A Risk Stratification Model for Health and Academic Outcomes in Children with Concussion Based on Novel Symptom Trajectory Typologies | 000 | 3 | NIH | 3/12/2025 | $554,454 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AI194953 | Immunomodulation in AAV gene therapy | 000 | 1 | NIH | 8/21/2025 | $3,192,404 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DA062639 | Project DEDUCE: Digital Envirotyping to Develop Understanding of Cigarette smoking and the Environment | 001 | 1 | NIH | 9/19/2025 | $0 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U01DK061713 | Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) | 002 | 24 | NIH | 7/3/2025 | $250,001 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DA062639 | Project DEDUCE: Digital Envirotyping to Develop Understanding of Cigarette smoking and the Environment | 000 | 1 | NIH | 7/4/2025 | $763,766 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01MD018977 | CO-LEADER: Intervention to Improve Patient-Provider Communication and Medication Adherence among Patients with Systemic Lupus Erythematosus | 001 | 3 | NIH | 3/31/2025 | $759,718 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01AI172451 | Calcineurin signaling cascades governing Cryptococcus virulence | 000 | 3 | NIH | 2/13/2025 | $652,751 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U2COD023375 | ECHO Coordinating Center (CC) - Kitting Expanded Scope | 003 | 9 | NIH | 9/12/2025 | $1,300,000 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U2COD023375 | ECHO Coordinating Center (CC) - Kitting Expanded Scope | 003 | 9 | NIH | 9/12/2025 | $2,125,289 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U2COD023375 | ECHO Coordinating Center (CC) - Kitting Expanded Scope | 003 | 9 | NIH | 9/12/2025 | $150,000 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K23MD017279 | Refinement and Testing of Implementation Strategies to Promote Psychotherapy Attendance for Depression among Latino/a Teens | 002 | 4 | NIH | 9/3/2025 | $0 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U2COD023375 | ECHO Coordinating Center (CC) - Kitting Expanded Scope | 003 | 9 | NIH | 9/12/2025 | $1,600,000 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U2COD023375 | ECHO Coordinating Center (CC) - Kitting Expanded Scope | 002 | 9 | NIH | 7/9/2025 | $7,002,175 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K23MD017279 | Refinement and Testing of Implementation Strategies to Promote Psychotherapy Attendance for Depression among Latino/a Teens | 001 | 4 | NIH | 4/17/2025 | $153,540 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R25HD094667 | UrogynCREST Program | 002 | 7 | NIH | 4/2/2025 | $157,912 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DA055414 | Microglial pruning of dopamine receptors and opioid abuse. | 001 | 4 | NIH | 4/10/2025 | $38,451 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | U2COD023375 | ECHO Coordinating Center (CC) - Kitting Expanded Scope | 001 | 9 | NIH | 6/5/2025 | $13,999,997 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | R01DA055414 | Microglial pruning of dopamine receptors and opioid abuse. | 000 | 4 | NIH | 2/27/2025 | $346,060 |
| | 2025 | 2025 | DUKE UNIVERSITY | 2200 W MAIN ST | DURHAM | NC | 27705-4640 | DURHAM | USA | K08CA304375 | Improving Engagement with Vaginal Dilator Therapy after Pelvic Radiation: A Pilot Randomized Controlled Trial | 000 | 1 | NIH | 8/7/2025 | $178,453 |
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