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Collaborative Care Office-Based Opioid Treatment for Adolescents and Young Adults

Award Number: K23DA045085
ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 10/05/2021
PERIOD OF PERFORMANCE END DATE: 06/30/2023

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Collaborative Care Office-Based Opioid Treatment for Adolescents and Young Adults - PROJECT SUMMARY: Risk for opioid use disorder (OUD) often begins in adolescence and young adulthood. Engaging and retaining adolescents and young adults (collectively, “youth”) in early, effective treatment to is critical in order to improve the life course trajectory of addiction. For adults with OUD, office-based opioid treatment (OBOT) with a collaborative care approach optimizes patient engagement and retention in care. This approach combines physician visits, nurse care management, and behavioral therapy. Collaborative care OBOT is especially promising for youth, who can receive treatment from a trusted primary care provider in the same familiar setting they receive their usual medical care. To date, however, OBOT has not been formally adapted for treating youth. The central objective of this project is to develop and pilot an OBOT model that is enhanced for youth and that is developmentally appropriate and family-centered. The project includes: (1) an analysis of Massachusetts Department of Public Health data to measure treatment patterns and outcomes among youth with OUD, thus identifying periods of high risk for loss to follow-up and drug use relapse during treatment; (2) qualitative interviews with youth, caretakers, and key informants (such as experienced OBOT providers and primary care providers of youth in areas of high OUD prevalence) to determine necessary modifications to the OBOT model for youth; and (3) a single-arm adaptive pilot study of OBOT enhanced for youth, using implementation and improvement science techniques to optimize the intervention. The Principal Investigator, Dr. Hadland, is an early career clinician-investigator with triple board certification in General Pediatrics, Adolescent Medicine, and Addiction Medicine, and prior research experience in clinical epidemiology. With this project, he seeks to enhance his skills in interventional research, focusing on developing analytic skills in advanced survival analysis and use of correlated data, acquiring foundational knowledge in intervention development, and using implementation and improvement science methodology to optimize an intervention initially designed for adults for use among youth. Dr. Hadland will conduct this research at Boston Medical Center and Boston University School of Medicine, national leaders in addiction medicine and research. The project is supported by an interdisciplinary mentorship and advisory team with expertise in advanced biostatistical analysis, qualitative research, intervention development, developmental psychology, and implementation and improvement science.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = -$38,367 )
2025	2021	BOSTON MEDICAL CENTER CORPORATION	1 BOSTON MEDICAL CTR PL	BOSTON	MA	02118	SUFFOLK	USA	Drug Use and Addiction Research Programs	000	4	10/1/2024	NON-COMPETING CONTINUATION	-$38,367
														Subtotal = -$38,367

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2022	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Drug Use and Addiction Research Programs	000	6	4/15/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2022 ( Subtotal = $218,914 )
2022	2022	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Drug Use and Addiction Research Programs	005	6	5/23/2022	NON-COMPETING CONTINUATION	$199,142
2022	2021	THE GENERAL HOSPITAL CORPORATION	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Drug Use and Addiction Research Programs	004	5	4/13/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$66,452
2022	2021	BOSTON MEDICAL CENTER CORPORATION	1 BOSTON MEDICAL CTR PL STE 1	BOSTON	MA	02118	SUFFOLK	USA	Drug Use and Addiction Research Programs	003	4	4/13/2022	NON-COMPETING CONTINUATION	-$564
2022	2021	BOSTON MEDICAL CENTER CORPORATION	1 BOSTON MEDICAL CTR PL STE 1	BOSTON	MA	02118	SUFFOLK	USA	Drug Use and Addiction Research Programs	000	4	12/17/2021	NON-COMPETING CONTINUATION	-$179,509
2022	2021	MASSACHUSETTS GENERAL HOSPITAL, THE	55 FRUIT ST	BOSTON	MA	02114	SUFFOLK	USA	Drug Use and Addiction Research Programs	001	5	12/17/2021	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$199,281
2022	2020	BOSTON MEDICAL CENTER CORPORATION	1 BOSTON MEDICAL CTR PL STE 1	BOSTON	MA	02118	SUFFOLK	USA	Drug Use and Addiction Research Programs	002	3	4/13/2022	NON-COMPETING CONTINUATION	-$65,888
														Subtotal = $218,914

Issue Date FY: 2021 ( Subtotal = $180,073 )
2021	2021	BOSTON MEDICAL CENTER CORPORATION	1 BOSTON MEDICAL CENTER PL STE 1	BOSTON	MA	02118	SUFFOLK	USA	Drug Use and Addiction Research Programs	000	4	6/15/2021	NON-COMPETING CONTINUATION	$180,073
														Subtotal = $180,073

Issue Date FY: 2020 ( Subtotal = $185,328 )
2020	2020	BOSTON MEDICAL CENTER CORPORATION	1 BOSTON MEDICAL CENTER PL STE 1	BOSTON	MA	02118	SUFFOLK	USA	Drug Use and Addiction Research Programs	000	3	5/29/2020	NON-COMPETING CONTINUATION	$185,328
														Subtotal = $185,328

Issue Date FY: 2019 ( Subtotal = $286,749 )
2019	2019	BOSTON MEDICAL CENTER CORPORATION	1 BOSTON MEDICAL CENTER PL STE 1	BOSTON	MA	02118	SUFFOLK	USA	Drug Use and Addiction Research Programs	000	1	7/2/2019	SUPPLEMENT FOR EXPANSION	$101,151
2019	2019	BOSTON MEDICAL CENTER CORPORATION	1 BOSTON MEDICAL CENTER PL STE 1	BOSTON	MA	02118	SUFFOLK	USA	Drug Use and Addiction Research Programs	001	2	7/17/2019	NON-COMPETING CONTINUATION	$185,598
														Subtotal = $286,749

Issue Date FY: 2018 ( Subtotal = $191,160 )
2018	2018	BOSTON MEDICAL CENTER CORPORATION	1 BOSTON MEDICAL CENTER PL STE 1	BOSTON	MA	02118	SUFFOLK	USA	Drug Use and Addiction Research Programs	000	1	6/22/2018	NEW	$191,160
														Subtotal = $191,160

Grand Total All Awards = $1,023,857

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Collaborative Care Office-Based Opioid Treatment for Adolescents and Young Adults

Award Number: K23DA045085

ORGANIZATION: NATIONAL INSTITUTE ON DRUG ABUSE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 10/05/2021

PERIOD OF PERFORMANCE END DATE: 06/30/2023

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