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Paul Calabresi Clinical Oncology Award

Award Number: K12CA088084
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 09/13/2000
PERIOD OF PERFORMANCE END DATE: 06/30/2027

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Paul Calabresi Clinical Oncology Award - Project Summary Although knowledge of cancer biology in the laboratory has increased exponentially in recent years, progress in cancer treatment in the clinic has been more gradual. To accelerate progress in the clinic, a larger group of exceptional clinician-investigators is needed to perform patient-oriented, hypothesis-driven therapeutic translational research. The MD Anderson (MDACC) K12 Paul Calabresi Program in Clinical Oncology has taken advantage of an extraordinary environment for clinical and translational research to help to fill this need. MDACC brings together 1,743 faculty and 40,000 new patients each year with a well-developed infrastructure for clinical and laboratory research and novel ideas that are supported by 378 NCI grants. For eight decades, MDACC investigators have made important contributions to clinical cancer research. Since the inception of the MDACC K12 Program in 2000, 35 junior-faculty investigators have been trained in patient-based translational research with the program's support. Of the 31 graduates, 28 (89%) remain in academia and 13 have led or contributed to discoveries that have changed the standard of cancer care. Among the 12 scholars trained since the last renewal, three are from under-represented minorities (URMs). During the current grant period, eleven of twelve (91%) scholars had either earned an additional advanced degree during the program or had previously earned an MS or PhD. Collectively, Calabresi Scholars have authored 485 peer-reviewed publications while participating in the program and 1,844 following graduation with impact factor >5 in 28.6% and >10 in 11.6%. They have competed successfully for $35M in grants and contracts. Over the next 5 years, faculty supported by this award will conduct hypothesis-driven clinical trials and will have the opportunity to earn an M.S. or Ph.D. in a newly chartered track in Clinical and Translational Science. They will participate in the monthly “Master Class” and the annual “Calabresi K Symposium”. Their Individualized Training Plans will include didactic classes, clinical trials, publications, grant applications, and long-range planning. Each Calabresi Scholar is guided by a clinical mentor and a translational mentor chosen from 40 experts in clinical, laboratory, and translational research. Particular emphasis will be placed on rigorous evaluation and recruitment of minority scholars. Our overall goal is to identify and develop careers of leaders who are needed to move an increasing number of new drugs and strategies from the laboratory to the clinic and to bring insights, images, data and tissue from the clinic to the laboratory, accelerating the development of more effective, less toxic personalized therapy. Funds are requested to include five junior faculty not only from MDACC, but also from Baylor College of Medicine and UT Health in Houston.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2024	THE UNIVERISTY OF TEXAS M.D. ANDERSON CANCER CENTER	1515 HOLCOMBE BLVD	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	23	4/11/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $569,799 )
2024	2024	THE UNIVERISTY OF TEXAS MD ANDERSON CANCER CENTER, A COMPONENT OF THE UNIVERISTY OF TEXAS SYSTEM	1515 HOLCOMBE BLVD	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	23	9/16/2024	NON-COMPETING CONTINUATION	$569,799
														Subtotal = $569,799

Issue Date FY: 2023 ( Subtotal = $663,405 )
2023	2023	UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER, THE	1515 HOLCOMBE BLVD	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	002	22	8/23/2023	NON-COMPETING CONTINUATION	$663,405
2023	2023	UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER, THE	1515 HOLCOMBE BLVD	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	003	22	9/1/2023	NON-COMPETING CONTINUATION	$0
2023	2022	UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER, THE	1515 HOLCOMBE BLVD	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	001	21	5/9/2023	COMPETING CONTINUATION	$247,651
2023	2020	UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER, THE	1515 HOLCOMBE BLVD	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	20	5/9/2023	NON-COMPETING CONTINUATION	-$247,651
														Subtotal = $663,405

Issue Date FY: 2022 ( Subtotal = $691,698 )
2022	2022	UNIVERSITY OF TEXAS M. D. ANDERSON CANCER CENTER, THE	1515 HOLCOMBE BLVD	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	21	5/23/2022	COMPETING CONTINUATION	$691,698
														Subtotal = $691,698

Issue Date FY: 2020 ( Subtotal = $690,503 )
2020	2020	UNIVERSITY OF TEXAS M D ANDERSON CANCER CENTER	1515 HOLCOMBE BLVD UNIT 207	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	20	6/29/2020	NON-COMPETING CONTINUATION	$690,503
														Subtotal = $690,503

Issue Date FY: 2019 ( Subtotal = $801,143 )
2019	2019	UNIVERSITY OF TEXAS M D ANDERSON CANCER CENTER	1515 HOLCOMBE BLVD UNIT 207	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	19	6/7/2019	NON-COMPETING CONTINUATION	$801,143
														Subtotal = $801,143

Issue Date FY: 2018 ( Subtotal = $202,024 )
2018	2018	UNIVERSITY OF TEXAS M D ANDERSON CANCER CENTER	1515 HOLCOMBE BLVD UNIT 207	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	18	6/29/2018	NON-COMPETING CONTINUATION	$202,024
														Subtotal = $202,024

Issue Date FY: 2017 ( Subtotal = $985,071 )
2017	2017	UNIVERSITY OF TEXAS M D ANDERSON CANCER CENTER	1515 HOLCOMBE BLVD UNIT 207	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	17	6/20/2017	NON-COMPETING CONTINUATION	$801,143
2017	2016	UNIVERSITY OF TEXAS M D ANDERSON CANCER CENTER	1515 HOLCOMBE BLVD UNIT 207	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	004	16	9/19/2017	COMPETING CONTINUATION	$260,055
2017	2014	UNIVERSITY OF TEXAS M D ANDERSON CANCER CENTER	1515 HOLCOMBE BLVD UNIT 207	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	001	15	9/14/2017	NON-COMPETING CONTINUATION	$17,294
2017	2014	UNIVERSITY OF TEXAS M D ANDERSON CANCER CENTER	1515 HOLCOMBE BLVD UNIT 207	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	003	15	9/19/2017	NON-COMPETING CONTINUATION	-$84,407
2017	2013	UNIVERSITY OF TEXAS M D ANDERSON CANCER CENTER	1515 HOLCOMBE BLVD UNIT 207	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	002	14	9/19/2017	NON-COMPETING CONTINUATION	-$9,014
														Subtotal = $985,071

Issue Date FY: 2016 ( Subtotal = $618,310 )
2016	2016	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	16	6/8/2016	COMPETING CONTINUATION	$618,310
														Subtotal = $618,310

Issue Date FY: 2014 ( Subtotal = $251,041 )
2014	2014	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	15	9/3/2014	NON-COMPETING CONTINUATION	$251,041
														Subtotal = $251,041

Issue Date FY: 2013 ( Subtotal = $650,081 )
2013	2013	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	14	9/6/2013	NON-COMPETING CONTINUATION	$650,081
														Subtotal = $650,081

Issue Date FY: 2012 ( Subtotal = $658,054 )
2012	2012	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	13	9/10/2012	NON-COMPETING CONTINUATION	$658,054
														Subtotal = $658,054

Issue Date FY: 2011 ( Subtotal = $649,162 )
2011	2011	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	12	8/29/2011	NON-COMPETING CONTINUATION	$649,162
														Subtotal = $649,162

Issue Date FY: 2010 ( Subtotal = $486,393 )
2010	2010	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	11	9/24/2010	COMPETING CONTINUATION	$486,393
														Subtotal = $486,393

Issue Date FY: 2009 ( Subtotal = $375,141 )
2009	2009	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	001	10	9/9/2009	NON-COMPETING CONTINUATION	$375,141
2009	2008	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	9	12/15/2008	NON-COMPETING CONTINUATION	$0
														Subtotal = $375,141

Issue Date FY: 2008 ( Subtotal = $545,376 )
2008	2008	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	9	9/17/2008	NON-COMPETING CONTINUATION	$545,376
														Subtotal = $545,376

Issue Date FY: 2007 ( Subtotal = $188,979 )
2007	2007	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	8	9/13/2007	NON-COMPETING CONTINUATION	$188,979
														Subtotal = $188,979

Issue Date FY: 2006 ( Subtotal = $652,683 )
2006	2006	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	7	9/26/2006	NON-COMPETING CONTINUATION	$652,683
														Subtotal = $652,683

Issue Date FY: 2005 ( Subtotal = $560,511 )
2005	2005	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	6	9/12/2005	COMPETING CONTINUATION	$560,511
														Subtotal = $560,511

Issue Date FY: 2004 ( Subtotal = $538,920 )
2004	2004	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	5	9/27/2004	NON-COMPETING CONTINUATION	$538,920
														Subtotal = $538,920

Issue Date FY: 2003 ( Subtotal = $538,920 )
2003	2003	UNIV OF TEXAS SYS CANCER CTR, M D ANDERSON HOSP/TUM INS	1515 HOLCOMBE BLVD, ROOM 202	HOUSTON	TX	77030	HARRIS	USA	Cancer Research Manpower	000	4	9/24/2003	NON-COMPETING CONTINUATION	$538,920
														Subtotal = $538,920

Grand Total All Awards = $12,933,974

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Paul Calabresi Clinical Oncology Award

Award Number: K12CA088084

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 09/13/2000

PERIOD OF PERFORMANCE END DATE: 06/30/2027

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