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A Systems Approach to Improve Safe Medication Management for Children with Medical Complexity

Award Number: K01MD016167
ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 05/13/2022
PERIOD OF PERFORMANCE END DATE: 01/31/2026

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A Systems Approach to Improve Safe Medication Management for Children with Medical Complexity - The proposed research addresses a key patient safety gap among children with medical complexity (CMC) transitioning between hospital and home—medication related harm. CMC are often on multiple and complex medication regimens and have intensive healthcare needs. As a result, they experience frequent transitions of care, across professional roles and care settings and during these transitions, CMC are at great risk for medication-related harm. Most transitional care interventions have been adopted from adult care settings and may not be adequate to address the unique needs of CMC and their family caregivers. Interventions that are grounded in the unique situations and complexities of such patients are needed to improve medication use safety and family experience of care. This proposal describes the PI’s plan to transition into an independent investigator by developing expertise in 1) participatory, human centered design to co-develop useful interventions, and 2) implementing and evaluating patient and family centered interventions. The proposal also describes a 4-year project for developing a prototype care transition medication safety intervention and generating early evidence on its usability and factors influencing its implementation. Aim 1: Patient journey mapping—will be used to elucidate medication safety risks and contexts during the hospital-to-home transition period. Journey maps will be used to capture and visually represent the medication use experience of families across professional settings and boundaries. The output of this aim will inform prototype design under Aim 2. Aim 2: Participatory, human centered design to co-design a prototype medication safety intervention. Through multiple, iterative co-design sessions involving healthcare workers and family caregivers, a team will design a prototype medication safety intervention informed by journey maps from Aim 1, current literature, and participant elicitations. The result will be a composite prototype ready for usability testing. Aim 3: Will test usability of prototype intervention with healthcare workers and family caregivers. Additionally, barriers and facilitators to prototype implementation will be explored. Taken together, all 3 aims will yield a final, refined prototype intervention designed to improve medication use safety during care transitions. Future work will involve a randomized controlled trial of the prototype medication safety intervention to formally evaluate its effectiveness in preventing or reducing medication related harm as well as improving the medication use experience of CMC and their family caregivers.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $126,131 )
2025	2025	PURDUE UNIVERSITY	2550 NORTHWESTERN AVE # 1100	WEST LAFAYETTE	IN	47906	TIPPECANOE	USA	Minority Health and Health Disparities Research	000	4	1/18/2025	NON-COMPETING CONTINUATION	$113,518
2025	2025	PURDUE UNIVERSITY	2550 NORTHWESTERN AVE # 1100	WEST LAFAYETTE	IN	47906	TIPPECANOE	USA	Minority Health and Health Disparities Research	001	4	4/1/2025	NON-COMPETING CONTINUATION	$12,613
														Subtotal = $126,131

Issue Date FY: 2024 ( Subtotal = $126,734 )
2024	2024	PURDUE UNIVERSITY	2550 NORTHWESTERN AVE # 1100	WEST LAFAYETTE	IN	47906	TIPPECANOE	USA	Minority Health and Health Disparities Research	000	3	1/6/2024	NON-COMPETING CONTINUATION	$114,060
2024	2024	PURDUE UNIVERSITY	2550 NORTHWESTERN AVE # 1100	WEST LAFAYETTE	IN	47906	TIPPECANOE	USA	Minority Health and Health Disparities Research	001	3	5/29/2024	NON-COMPETING CONTINUATION	$12,674
														Subtotal = $126,734

Issue Date FY: 2023 ( Subtotal = $127,580 )
2023	2023	PURDUE UNIVERSITY	2550 NORTHWESTERN AVE STE 1900	WEST LAFAYETTE	IN	47906	TIPPECANOE	USA	Minority Health and Health Disparities Research	000	2	2/26/2023	NON-COMPETING CONTINUATION	$127,580
														Subtotal = $127,580

Issue Date FY: 2022 ( Subtotal = $129,784 )
2022	2022	PURDUE UNIVERSITY	2550 NORTHWESTERN AVE STE 1900	WEST LAFAYETTE	IN	47906	TIPPECANOE	USA	Minority Health and Health Disparities Research	000	1	5/13/2022	NEW	$129,784
														Subtotal = $129,784

Grand Total All Awards = $510,229

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A Systems Approach to Improve Safe Medication Management for Children with Medical Complexity

Award Number: K01MD016167

ORGANIZATION: NATIONAL CENTER ON MINORITY HEALTH AND HEALTH DISPARITIES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 05/13/2022

PERIOD OF PERFORMANCE END DATE: 01/31/2026

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