| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2025 ( Subtotal = $32,822,373 ) (Continued on the next page) |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01AI059374 | Adenoviral Vector-based Pandemic Influenza Vaccine | 000 | 12 | NIH | 4/29/2025 | $467,130 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | K01HD108393 | Meeting young people where they are: Using technology to promote resilience among child maltreatment victims | 000 | 3 | NIH | 4/7/2025 | $130,072 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01MH130442 | Childhood adversity, DNA methylation, and risk for depression: A longitudinal study of protective factors and sensitive periods in development | 001 | 3 | NIH | 4/7/2025 | $649,819 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F31AG084329 | Small Molecule Degraders of Tryptophan 2,3-Dioxygenase Enzyme (TDO) as Novel Treatments for Neurodegenerative Disease | 001 | 2 | NIH | 6/23/2025 | $1,644 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F31AG084329 | Small Molecule Degraders of Tryptophan 2,3-Dioxygenase Enzyme (TDO) as Novel Treatments for Neurodegenerative Disease | 000 | 2 | NIH | 12/27/2024 | $47,694 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01NS131160 | Improving glioma radiotherapy by theragnostic targeting of tumor-supporting macrophages | 000 | 3 | NIH | 3/26/2025 | $343,172 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01HL167046 | Rational optimization of combinatorial therapies for the treatment of rare cystic fibrosis variants | 000 | 3 | NIH | 5/21/2025 | $686,508 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01DC020179 | Estrogenic regulation of systemic vocal fold dehydration | 001 | 4 | NIH | 4/25/2025 | $61,868 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01DC020179 | Estrogenic regulation of systemic vocal fold dehydration | 000 | 4 | NIH | 3/11/2025 | $556,809 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | H79TI085525 | Advanced Practice NuRses' Opioid Use Disorder Education Through a Massive Open Online Course (APROUD-MOOC) | 003 | 3 | SAMHSA | 6/26/2025 | $244,933 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01EB033788 | Maternal mHealth blood hemoglobin analysis with informed deep learning | 000 | 3 | NIH | 6/4/2025 | $502,918 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM147412 | Monitoring the three-dimensional motion of chromatin at single molecule resolution | 000 | 5 | NIH | 6/20/2025 | $382,987 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01ES033486 | Addressing Tetrachloroethylene Exposure in an Impacted Community: Residents' Concerns, Neurotoxic Effects, and Exposure Reduction | 000 | 3 | NIH | 4/28/2025 | $559,609 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM147579 | Robust Sequence-defined Nanocages with Protein-mimetic Cavities | 000 | 5 | NIH | 6/17/2025 | $376,569 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01DE030413 | Dose analysis for translating animal based vibrational force study for accelerating orthodontic tooth movement to clinic | 002 | 5 | NIH | 3/18/2025 | $406,528 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01DE030413 | Dose analysis for translating animal based vibrational force study for accelerating orthodontic tooth movement to clinic | 006 | 5 | NIH | 5/8/2025 | $0 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21AG094190 | The epigenome-metabolism nexus as a driver of circadian disruption in Alzheimer's disease | 000 | 1 | NIH | 5/13/2025 | $419,005 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | K08AG071985 | Small molecule inhibitors of hyperphosphorylated tau aggregation in Alzheimer's disease: lead optimization, and proof of concept in a rodent model | 000 | 4 | NIH | 6/3/2025 | $164,430 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01AG073634 | Leg heat therapy to improve functional performance in peripheral artery disease | 000 | 4 | NIH | 4/18/2025 | $396,508 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01AG073634 | Leg heat therapy to improve functional performance in peripheral artery disease | 001 | 4 | NIH | 6/20/2025 | $35,244 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01DK131049 | Restoring Ocrl1 function in Lowe Syndrome and Dent-2 disease | 000 | 5 | NIH | 6/10/2025 | $342,239 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01CA293514 | CAR neutrophils produced in vivo to remodel tumor microenvironment and treat glioblastoma | 000 | 1 | NIH | 4/21/2025 | $641,936 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM138002 | Mining Cryptic Biosynthetic Gene Clusters for Novel Bioactive Compounds and Biocatalysts | 000 | 6 | NIH | 5/27/2025 | $544,123 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01DC019129 | Implicit Structural Priming as a Treatment Component in Aphasia | 000 | 5 | NIH | 4/25/2025 | $594,362 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01NS119917 | Pharmacological validation of adenylyl cyclase 1 as a drug target for chronic pain | 000 | 5 | NIH | 11/25/2024 | $337,908 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01MH120109 | Biobehavioral validation of the ADHD emotion dysregulation phenotype | 000 | 6 | NIH | 3/4/2025 | $532,169 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R25EB031389 | A Clinical Immersion Program to Train Biomedical Engineers to Identify Indiana's Urban Health Needs | 002 | 6 | NIH | 4/18/2025 | $43,200 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01CA205420 | Enhancing miRNA Therapeutics through Vehicle Free Delivery | 001 | 7 | NIH | 5/22/2025 | $38,612 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R03CA283236 | Anti-cancer effects of tocotrienols and a carboxychromanol in an innovative colon cancer model | 000 | 2 | NIH | 3/20/2025 | $74,517 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01CA205420 | Enhancing miRNA Therapeutics through Vehicle Free Delivery | 000 | 7 | NIH | 2/28/2025 | $347,515 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01EY034901 | Smart soft contact lenses for continuous 24-hour monitoring of intraocular pressure in glaucoma care | 000 | 2 | NIH | 3/19/2025 | $511,258 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01HL167828 | Aerosol delivery of combinational therapeutics targeting deadly lung infections | 000 | 2 | NIH | 3/7/2025 | $535,437 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM155449 | Leveraging cell-instructive hydrogels to understand microenvironmental impact on wound healing processes | 000 | 2 | NIH | 4/10/2025 | $379,755 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R00CA279915 | Defining PRC1.1 as a gatekeeper of lineage plasticity and response to anti-GD2 therapy | 001 | 3 | NIH | 5/9/2025 | $242,168 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01DC018593 | Lexico-semantic abilities in early language growth and delay | 001 | 5 | NIH | 5/20/2025 | $58,688 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01DC018593 | Lexico-semantic abilities in early language growth and delay | 000 | 5 | NIH | 1/28/2025 | $528,187 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01EY033734 | Chromatin connects metabolism to circadian gene regulation in the aging eye | 000 | 3 | NIH | 11/27/2024 | $373,390 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01ES035019 | PFAS induced alterations in reward processing | 000 | 2 | NIH | 11/5/2024 | $538,810 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R37CA265926 | Engineer Biomimetic Microfluidic Models to Investigate and Reprogram Tumor Associated Neutrophils for Cancer Therapy | 000 | 4 | NIH | 5/9/2025 | $349,257 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01ES033173 | Compromised Resolution of Inflammation following Nanoparticle Exposure in Metabolic Syndrome | 000 | 4 | NIH | 1/6/2025 | $337,723 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | K01MD016167 | A Systems Approach to Improve Safe Medication Management for Children with Medical Complexity | 001 | 4 | NIH | 4/1/2025 | $12,613 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | K01MD016167 | A Systems Approach to Improve Safe Medication Management for Children with Medical Complexity | 000 | 4 | NIH | 1/18/2025 | $113,518 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01MH126213 | Tourette Syndrome genetics and neuroimaging international collaborative study | 000 | 4 | NIH | 12/20/2024 | $417,475 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21HD110656 | Supporting high-intensity interval training with mindfulness for enhancing childhood executive function | 000 | 2 | NIH | 5/29/2025 | $191,893 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01GM152915 | Highly Sensitive Novel Neutron Activation Analysis (NAA) Technology to Quantify Multiple Metals in Human Bone In Vivo | 000 | 2 | NIH | 6/2/2025 | $389,502 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM150676 | Development of a Chemical Biology Toolbox to Investigate Histone Monoaminylation | 002 | 4 | NIH | 5/26/2025 | $392,500 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01ES035429 | Comparative neurotoxicity of PFAS | 000 | 2 | NIH | 4/2/2025 | $656,288 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01GM152701 | Mechanisms Underlying Regulation of PLCbeta by heterotrimeric G proteins | 000 | 2 | NIH | 6/25/2025 | $392,016 |
| | 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21DC021481 | Optimizing the assessment of auditory attention in aphasia | 001 | 2 | NIH | 4/22/2025 | $18,985 |
|
