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 | Issue Date FY: 2025 ( Subtotal = $9,750,819 ) (Continued on the next page) |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01CA295436 | Primary screening and hit follow up to identify the first selective inhibitors of PLC?1 and PLC?2 | 000 | 1 | NIH | 1/24/2025 | $572,254 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01ES010563 | Mechanisms of Manganese Neurotoxicity | 002 | 24 | NIH | 12/3/2024 | $680,811 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R13HD070625 | Expanding engagement and mentorship of developing scientists through ISDP Annual Meeting participation | 000 | 26 | NIH | 11/5/2024 | $9,000 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01MH126213 | Tourette Syndrome genetics and neuroimaging international collaborative study | 000 | 4 | NIH | 12/20/2024 | $417,475 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21DC021481 | Optimizing the assessment of auditory attention in aphasia | 000 | 2 | NIH | 12/23/2024 | $170,863 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R00CA263036 | Investigating gastric inflammation and preneoplastic progression driven by Helicobacter pylori infection | 000 | 4 | NIH | 1/7/2025 | $97,817 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | K01MD016167 | A Systems Approach to Improve Safe Medication Management for Children with Medical Complexity | 000 | 4 | NIH | 1/18/2025 | $113,518 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01EY033734 | Chromatin connects metabolism to circadian gene regulation in the aging eye | 000 | 3 | NIH | 11/27/2024 | $373,390 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | DP2AI164293 | Partial maturation in mosquito-borne flaviviruses: developing new approaches to characterize the role of lattice heterogeneity in fusion, infectivity, and antibody neutralization | 000 | 4 | NIH | 1/17/2025 | $452,988 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01ES035019 | PFAS induced alterations in reward processing | 000 | 2 | NIH | 11/5/2024 | $538,810 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01CA258887 | Discovery of small molecule inhibitors for protein N-terminal acetyltransferase D | 000 | 4 | NIH | 12/4/2024 | $470,345 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01ES033173 | Compromised Resolution of Inflammation following Nanoparticle Exposure in Metabolic Syndrome | 000 | 4 | NIH | 1/6/2025 | $337,723 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R00MD016946 | Identifying determinants of ADAR-dependency in triple-negative breast cancer | 000 | 5 | NIH | 12/13/2024 | $224,101 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F30DC020916 | Place and Time Processing of Pitch in the Context of Cochlear Dysfunction | 000 | 3 | NIH | 12/5/2024 | $53,994 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F30DC020916 | Place and Time Processing of Pitch in the Context of Cochlear Dysfunction | 001 | 3 | NIH | 1/3/2025 | $0 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01CA271597 | Impact of hypoxia on lipid metabolism in obesity-driven breast cancer progression | 000 | 3 | NIH | 11/26/2024 | $577,471 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | U01NS118302 | Optimization of Clear Optically Matched Panoramic Access Channel Technique (COMPACT) for large-scale deep-brain neurophotonic interface | 000 | 4 | NIH | 12/26/2024 | $386,452 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F31AG084329 | Small Molecule Degraders of Tryptophan 2,3-Dioxygenase Enzyme (TDO) as Novel Treatments for Neurodegenerative Disease | 000 | 2 | NIH | 12/27/2024 | $47,694 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 Northwestern Ave | West Lafayette | IN | 47906-1332 | TIPPECANOE | USA | H8012846 | Health Center Program | 00 | 16 | HRSA | 12/19/2024 | $1,007,066 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | H8012846 | Health Center Program | 01 | 16 | HRSA | 1/6/2025 | $0 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01DC018593 | Lexico-semantic abilities in early language growth and delay | 000 | 5 | NIH | 1/28/2025 | $528,187 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01NS119917 | Pharmacological validation of adenylyl cyclase 1 as a drug target for chronic pain | 001 | 5 | NIH | 11/29/2024 | $69,619 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01NS119917 | Pharmacological validation of adenylyl cyclase 1 as a drug target for chronic pain | 000 | 5 | NIH | 11/25/2024 | $337,908 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM128894 | Harnessing the In Vitro Selection for Activity-based Proteomics and Chemical Probe Development | 001 | 7 | NIH | 12/23/2024 | $347,602 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F31GM154474 | Electrochemical Fluorination for Organic Synthesis | 000 | 1 | NIH | 11/29/2024 | $48,974 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F32DC022782 | Understanding the physiological roles of MOC efferent pathways for hearing in noise | 002 | 1 | NIH | 1/6/2025 | $0 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F32DC022782 | Understanding the physiological roles of MOC efferent pathways for hearing in noise | 000 | 1 | NIH | 12/3/2024 | $73,828 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F32DC022782 | Understanding the physiological roles of MOC efferent pathways for hearing in noise | 001 | 1 | NIH | 12/3/2024 | $0 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01GM097332 | The Role of DEAD-box Proteins in Gene Expression | 000 | 13 | NIH | 1/7/2025 | $294,943 |
| 2025 | 2025 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21ES036308 | Synthesis of Environmentally Relevant Nanoplastics and their Toxicological Consequences Mediated by Environmental Pollutants and Biomolecule Adsorption | 000 | 1 | NIH | 11/27/2024 | $428,387 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM124661 | Fluorination and Fluoroalkylation Strategies for Synthetic and Medicinal Chemistry | 000 | 9 | NIH | 11/8/2024 | $0 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM119652 | EXCITED-STATE CATALYSIS IN ORGANIC SYNTHESIS | 000 | 10 | NIH | 11/18/2024 | $0 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM119787 | Neutrophil migration and inflammation | 000 | 9 | NIH | 11/29/2024 | $0 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | U01NS126052 | Engineering the Neuronal Response to Electrical Microstimulation | 002 | 3 | NIH | 1/8/2025 | $233,798 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | U01NS126052 | Engineering the Neuronal Response to Electrical Microstimulation | 002 | 3 | NIH | 1/8/2025 | $59,022 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM124791 | Transition Metal Catalyzed Reductive Carbene Transfer Reactions | 000 | 8 | NIH | 11/13/2024 | $0 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM124913 | Roles of ion-channel mediated bioelectricity in developmental patterning | 000 | 8 | NIH | 11/8/2024 | $0 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | P30CA023168 | Cancer Center Support Grant | 000 | 44 | NIH | 11/25/2024 | $0 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM119785 | Ultra-high resolution structural and molecular imaging of cells and tissues | 000 | 9 | NIH | 11/29/2024 | $0 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01ES010563 | Mechanisms of Manganese Neurotoxicity | 001 | 23 | NIH | 10/17/2024 | $61,708 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM152086 | Molecular Mechanisms of Membrane Protein Misfolding and Quality Control in Cellular Proteostasis | 000 | 1 | NIH | 11/18/2024 | $0 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R00CA279915 | Defining PRC1.1 as a gatekeeper of lineage plasticity and response to anti-GD2 therapy | 000 | 2 | NIH | 10/11/2024 | $6,832 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | UH3TR004139 | High throughput infrastructure for reaction screening and bioassays | 000 | 3 | NIH | 10/18/2024 | $2,848 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R00CA263036 | Investigating gastric inflammation and preneoplastic progression driven by Helicobacter pylori infection | 001 | 3 | NIH | 1/8/2025 | $0 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21AI170712 | Role of DDX5 in Hepatitis B virus transcription and hepatocarcinogenesis | 000 | 2 | NIH | 12/18/2024 | $0 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01EY035159 | Long-acting formulations of griseofulvin for ocular neovascularization therapy | 000 | 2 | NIH | 11/25/2024 | $0 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01EY035159 | Long-acting formulations of griseofulvin for ocular neovascularization therapy | 002 | 2 | NIH | 12/11/2024 | $329,007 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R35GM153191 | Novel Ion Chemistry and Instrument Development for the Characterization of Proteins, Nucleic Acids, and Heterogeneous Bio-complexes via Tandem Mass Spectrometry | 000 | 1 | NIH | 11/21/2024 | $0 |
| 2025 | 2024 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE # 1100 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | H79SM087877 | Northwest Indiana Identification and Management of Pediatric Experiences of Trauma and Underlying Stress (NWI IMPETUS) | 001 | 2 | SAMHSA | 1/16/2025 | $0 |
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