| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2022 ( Subtotal = $50,830,961 ) (Continued on the next page) |
| | 2022 | 2022 | PURDUE UNIVERSITY | 155 S GRANT ST | WEST LAFAYETTE | IN | 47907-2114 | TIPPECANOE | USA | UH3DA048774 | Injectable naltrexone 2-month depot formulations | 000 | 3 | NIH | 1/7/2022 | $888,085 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01GM133840 | Building protein structure models for intermediate resolution cryo-electron microscopy maps | 000 | 3 | NIH | 7/25/2022 | $305,459 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | K08AG071985 | Small molecule inhibitors of hyperphosphorylated tau aggregation in Alzheimer's disease: lead optimization, and proof of concept in a rodent model | 000 | 1 | NIH | 5/13/2022 | $164,221 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F30HL162452 | Spatiotemporal and Deep Learning Analysis of Cardiac Imaging for Predictive Risk Stratification in Duchenne Muscular Dystrophy | 000 | 1 | NIH | 8/5/2022 | $54,252 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | K01MD016167 | A Systems Approach to Improve Safe Medication Management for Children with Medical Complexity | 000 | 1 | NIH | 5/13/2022 | $129,784 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | RF1NS124779 | Validation of HYPE as an Actionable Target for Alzheimer's Disease | 000 | 1 | NIH | 7/19/2022 | $1,162,500 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | S10OD030507 | New X-ray Diffractometer and Detector for Purdue Macromolecular Crystallography | 000 | 1 | NIH | 7/18/2022 | $859,933 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | UG3TR004139 | High throughput infrastructure for reaction screening and bioassays | 000 | 1 | NIH | 5/30/2022 | $898,292 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F31CA275390 | Investigations into ubiquitin binding proteins using structure guided reactivity | 001 | 1 | NIH | 7/29/2022 | $0 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F31CA275390 | Investigations into ubiquitin binding proteins using structure guided reactivity | 000 | 1 | NIH | 7/29/2022 | $46,752 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01AG073634 | Leg heat therapy to improve functional performance in peripheral artery disease | 000 | 1 | NIH | 5/9/2022 | $478,952 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21DK128715 | Swallowable smart capsule for targeted gastrointestinal microbiome sampling | 001 | 1 | NIH | 7/21/2022 | $0 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21DK128715 | Swallowable smart capsule for targeted gastrointestinal microbiome sampling | 000 | 1 | NIH | 6/10/2022 | $185,242 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | U01CA240346 | Nucleolin recognition of MYC promoter G-quadruplex and its role in MYC regulation by MycG4-ligands | 002 | 3 | NIH | 7/8/2022 | $65,188 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | U01CA240346 | Nucleolin recognition of MYC promoter G-quadruplex and its role in MYC regulation by MycG4-ligands | 001 | 3 | NIH | 7/7/2022 | $375,488 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | U01CA240346 | Nucleolin recognition of MYC promoter G-quadruplex and its role in MYC regulation by MycG4-ligands | 000 | 3 | NIH | 4/1/2022 | $284,471 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F31GM145170 | Structural and Functional Characterization of METTL13 | 000 | 1 | NIH | 7/27/2022 | $46,752 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01CA267978 | 3H-pyrazolo[4,3-f]quinoline-containing compounds as selective and tunable protein kinase inhibitors | 000 | 1 | NIH | 5/10/2022 | $495,845 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21AT011391 | Pregnane X receptor (PXR)-activating gut bacterial metabolites | 000 | 1 | NIH | 4/8/2022 | $200,198 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21AG077058 | m6A RNA modification as a regulator of R-loop homeostasis and gene expression in aging and neurodegeneration | 000 | 1 | NIH | 4/7/2022 | $375,488 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21LM013711 | FIrst REsponse BUrn Diagnostic System (FIRE-BUDS) | 000 | 1 | NIH | 3/1/2022 | $211,852 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01GM127884 | Unraveling the mechanism by which the BAM complex mediates OMP biogenesis | 000 | 4 | NIH | 5/16/2022 | $296,343 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01ES033173 | Compromised Resolution of Inflammation following Nanoparticle Exposure in Metabolic Syndrome | 000 | 1 | NIH | 3/25/2022 | $337,723 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01DC020179 | Estrogenic regulation of systemic vocal fold dehydration | 000 | 1 | NIH | 3/21/2022 | $630,793 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 155 S GRANT ST | WEST LAFAYETTE | IN | 47907-2114 | TIPPECANOE | USA | DP2AI164293 | Partial maturation in mosquito-borne flaviviruses: developing new approaches to characterize the role of lattice heterogeneity in fusion, infectivity, and antibody neutralization | 000 | 1 | NIH | 1/20/2022 | $425,620 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F32GM145110 | Structural Characterization of Gbetagamma-Phospholipase C complexes | 003 | 1 | NIH | 5/25/2022 | $1 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F32GM145110 | Structural Characterization of Gbetagamma-Phospholipase C complexes | 002 | 1 | NIH | 5/11/2022 | $1,191 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 155 S GRANT ST | WEST LAFAYETTE | IN | 47907-2114 | TIPPECANOE | USA | F32GM145110 | Structural Characterization of Gbetagamma-Phospholipase C complexes | 000 | 1 | NIH | 1/11/2022 | $66,390 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | F32GM145110 | Structural Characterization of Gbetagamma-Phospholipase C complexes | 001 | 1 | NIH | 1/11/2022 | $0 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01MH126213 | Tourette Syndrome genetics and neuroimaging international collaborative study | 001 | 1 | NIH | 6/27/2022 | $55,093 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01MH126213 | Tourette Syndrome genetics and neuroimaging international collaborative study | 000 | 1 | NIH | 3/3/2022 | $521,906 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 155 S GRANT ST | WEST LAFAYETTE | IN | 47907-2114 | TIPPECANOE | USA | R21CA270879 | Targeting Tryptophan Dioxygenase Degradation for Suppression of Tumor Immune Evasion | 000 | 1 | NIH | 1/27/2022 | $220,632 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 155 S GRANT ST | WEST LAFAYETTE | IN | 47907-2114 | TIPPECANOE | USA | R01AR079235 | Targeting PTEN to ameliorate muscular dystrophy in a mouse model | 000 | 1 | NIH | 1/27/2022 | $333,072 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 155 S GRANT ST | WEST LAFAYETTE | IN | 47907-2114 | TIPPECANOE | USA | R01CA258887 | Discovery of small molecule inhibitors for protein N-terminal acetyltransferase D | 000 | 1 | NIH | 11/29/2021 | $559,725 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R33AI140474 | Smartphone-based diagnostic for HIV self-testing | 001 | 5 | NIH | 7/26/2022 | $150,000 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R33AI140474 | Smartphone-based diagnostic for HIV self-testing | 001 | 5 | NIH | 7/26/2022 | $543,585 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01GM143268 | Molecular Mechanisms of Stem Cell Homeostasis in Arabidopsis | 000 | 2 | NIH | 6/10/2022 | $310,365 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01DK131049 | Restoring Ocrl1 function in Lowe Syndrome and Dent-2 disease | 000 | 2 | NIH | 7/25/2022 | $344,921 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01EY033000 | Development of Nanoneedle Array for Painless and Long-Term Sustained Intraocular Drug Delivery | 001 | 2 | NIH | 7/28/2022 | $371,079 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21AG070447 | Small molecule inhibitors of hyperphosphorylated tau aggregation and cytotoxicity for the development of Alzheimer?s therapeutics | 000 | 2 | NIH | 6/2/2022 | $181,738 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21AT011565 | Gut bacterial O-demethylation | 000 | 2 | NIH | 8/10/2022 | $244,735 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | H8012846 | Health Center Cluster | 02 | 13 | HRSA | 7/18/2022 | $0 |
| | 2022 | 2022 | Purdue University | 155 S GRANT ST | West Lafayette | IN | 47907-2114 | TIPPECANOE | USA | H8012846 | Health Center Cluster | 00 | 13 | HRSA | 1/5/2022 | $1,812,719 |
| | 2022 | 2022 | Purdue University | 2550 Northwestern Ave Ste 1900 | West Lafayette | IN | 47906-1332 | TIPPECANOE | USA | H8012846 | Health Center Cluster | 01 | 13 | HRSA | 5/18/2022 | $604,240 |
| | 2022 | 2022 | Purdue University | 2550 Northwestern Ave Ste 1900 | West Lafayette | IN | 47906-1332 | TIPPECANOE | USA | T9430876 | Advanced Nursing Education Workforce | 00 | 6 | HRSA | 6/2/2022 | $697,356 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R01AI158649 | SARS-CoV-2 protease inhibitors for treating COVID-19 | 000 | 2 | NIH | 7/19/2022 | $750,974 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R25ES033045 | Distance Education and Training on Emerging Contaminants and Technologies (DETECT) | 000 | 2 | NIH | 8/10/2022 | $222,832 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21EY032382 | Optical gearbox for high speed neural recording | 000 | 2 | NIH | 5/5/2022 | $239,750 |
| | 2022 | 2022 | PURDUE UNIVERSITY | 2550 NORTHWESTERN AVE STE 1900 | WEST LAFAYETTE | IN | 47906-1332 | TIPPECANOE | USA | R21AI151723 | T cell regulation by adult prostate stem cells | 000 | 2 | NIH | 3/21/2022 | $188,091 |
|
