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The Impact of a Targeted CRC Screening Intervention among Latinos in Central PA

Award Number: K01CA151752
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 09/30/2016
PERIOD OF PERFORMANCE END DATE: 08/31/2017

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The Impact of a Targeted CRC Screening Intervention among Latinos in Central PA - There is no change to the original grant, or scope of the work. Abstract remains unchanged. See grant. ABSTRACT It is widely recognized that colorectal cancer (CRC) is one of the most preventable cancers. If adenomatous polyps detected by screening were removed before they transformed into cancers, a decrease in new CRCs and in related mortality would follow. Unfortunately, cancer screening rates are low throughout Appalachia, including for Latino residents in PA. Further, Latinos are more likely to be diagnosed at later stage than Whites, have a lower survival rate and less access to quality treatment. Our long-term goal is to increase CRC screening uptake among Latinos in urban and rural central Pennsylvania (PA). Our central hypothesis is that a targeted CRC screening intervention can increase uptake over a non-targeted approach for this population. The specific objectives of the current proposal are to develop, implement and evaluate a targeted CRC screening intervention to increase CRC screening uptake. We will measure actual CRC uptake in both the control and intervention arm as a method to determinate completion rates. To prepare for my K01 application during my post-doc training, I led the design, implementation, and analysis of a CRC-related Latino study that provided preliminary data for theK01 work. In 04/09, utilizing the ACCN coalitions in PA, I conducted eight focus groups (FG) to identify barriers to CRC screenings among Latinos. We identified several substantial barriers to CRC screening for this population, including a significant barrier heretofore unmentioned in literature related to CRC screenings. Spanish-speaking patients want to have family members or close friends in the doctor office and health-related education classes. This barrier was reported across all groups and likely links to the desire for a strong social support that influences their CRC screening behavior. Another finding is that urban residents had some prior knowledge of risk factors associated with CRC screening while rural residents reported no prior knowledge and were unable to list any associated CRC risk factor. A high acceptability of the provider-recommended take-home fecal immunochemical test (FIT) for these Latinos was also reported. We exceeded our study recruitment goal. The same partnered Latino leaders are committed to the K01 proposed work. The K01 study design is a randomized, community-based, participatory design to determine completion of a provider-recommended, take-home FIT kit without (control) and with social support (intervention) among a sample of average-risk, urban and rural Appalachian Latino adults age 50 and older not currently adherent to national CRC screening guidelines (N=264).Each consented participant will attend a one-time, community- based CRC screening educational program offered at one of the eight study sites located in Central PA. The proposal is innovative because it combines provider-recommended FIT screening test with an education program and social support for Latinos in a randomized, community-based participatory research design. Further, it will provide preliminary data for evidence-based methods to increase CRC screening rates among Latinos throughout Appalachia, the focus of a future NIH NC1 R-series grant application.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2018 ( Subtotal = -$18,539 )
2018	2015	PENNSYLVANIA STATE UNIVERSITY, THE	500 UNIVERSITY DR C1607	HERSHEY	PA	17033	DAUPHIN	USA	Cancer Research Manpower	000	6	1/31/2018	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	-$18,539
														Subtotal = -$18,539

Issue Date FY: 2017 ( Subtotal = $0 )
2017	2015	PENNSYLVANIA STATE UNIVERSITY, THE	500 UNIVERSITY DR C1607	HERSHEY	PA	17033	DAUPHIN	USA	Cancer Research Manpower	001	6	1/17/2017	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$19,841
2017	2015	ALLEGHENY-SINGER RESEARCH INSTITUTE	320 E NORTH AVE	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Research Manpower	000	5	1/17/2017	NON-COMPETING CONTINUATION	-$19,841
														Subtotal = $0

Issue Date FY: 2016 ( Subtotal = $1 )
2016	2015	ALLEGHENY SINGER RESEARCH CORP	320 East North Avenue	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Research Manpower	000	5	9/13/2016	NON-COMPETING CONTINUATION	-$96,359
2016	2015	MILTON S HERSHEY MEDICAL CENTER	500 UNIVERSITY DRIVE, POB 850	HERSHEY	PA	17033	DAUPHIN	USA	Cancer Research Manpower	001	6	9/14/2016	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$96,360
														Subtotal = $1

Issue Date FY: 2015 ( Subtotal = $137,943 )
2015	2015	ALLEGHENY SINGER RESEARCH CORP	320 East North Avenue	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Research Manpower	000	5	8/4/2015	NON-COMPETING CONTINUATION	$137,943
														Subtotal = $137,943

Issue Date FY: 2014 ( Subtotal = $137,943 )
2014	2014	ALLEGHENY SINGER RESEARCH CORP	320 East North Avenue	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Research Manpower	000	4	8/21/2014	NON-COMPETING CONTINUATION	$137,943
														Subtotal = $137,943

Issue Date FY: 2013 ( Subtotal = $137,943 )
2013	2013	ALLEGHENY SINGER RESEARCH CORP	2 ALLEGHENY CTR, 11TH FLOOR	PITTSBURGH	PA	15212	ALLEGHENY	USA	Cancer Research Manpower	001	3	9/12/2013	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$137,943
2013	2012	MILTON S HERSHEY MEDICAL CENTER	500 UNIVERSITY DRIVE, POB 850	HERSHEY	PA	17033	DAUPHIN	USA	Cancer Research Manpower	000	2	9/11/2013	NON-COMPETING CONTINUATION	$0
														Subtotal = $137,943

Issue Date FY: 2012 ( Subtotal = $137,943 )
2012	2012	MILTON S HERSHEY MEDICAL CENTER	500 UNIVERSITY DRIVE, POB 850	HERSHEY	PA	17033	DAUPHIN	USA	Cancer Research Manpower	000	2	8/27/2012	NON-COMPETING CONTINUATION	$137,943
														Subtotal = $137,943

Issue Date FY: 2011 ( Subtotal = $137,943 )
2011	2011	MILTON S HERSHEY MEDICAL CENTER	500 UNIVERSITY DRIVE, POB 850	HERSHEY	PA	17033	DAUPHIN	USA	Cancer Research Manpower	000	1	9/20/2011	NEW	$137,943
														Subtotal = $137,943

Grand Total All Awards = $671,177

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The Impact of a Targeted CRC Screening Intervention among Latinos in Central PA

Award Number: K01CA151752

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 09/30/2016

PERIOD OF PERFORMANCE END DATE: 08/31/2017

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