Friday, April 19, 2024 4/19/2024

Hospital-Associated Respiratory Virus Infections: Molecular Epidemiology, Clinical Outcomes, and Cost-Effectiveness of Interventions - COVID-19 Administrative Supplement

Award Number: K01AI141579
ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

Group Awards By Issue Date FY or Funding FY:

View Award Abstract

PROJECT SUMMARY / ABSTRACT The COVID-19 pandemic has strained hospital capacity and led to shortages in personal protective equipment and testing supplies. This is particularly concerning because the SARS-CoV-2 virus that causes COVID-19 has resulted in notable healthcare associated outbreaks, as have other novel coronaviruses such as SARS and MERS. Past studies have shown that these outbreaks are preventable with prompt diagnosis of cases and appropriate use of personal protective equipment. In the face of shortages, hospitals must make rapid decisions on strategies to room patients, assign infection control precautions, ration personal protective equipment, and maintain adequate staffing. Accurate data and projections are needed to inform these decisions and evaluating their success is critical to managing the ongoing outbreak and informing future response. This need can be met by applying the existing aims of K01AI141579 to hospital-associated SARS- CoV-2 infection. The overall objective of the existing K01 project is to support Josh Petrie, PhD in the development of expertise in healthcare epidemiology, state-of-the-art molecular methods, and advanced modeling techniques. Completion of this objective is in progress through focused training and career development activities in healthcare epidemiology, next generation sequencing, bioinformatics, cost- effectiveness analysis, and mathematical modeling that is overseen by an excellent team of mentors. The skills that are being developed by the training and career development objectives are strengthened by mentored research to accomplish the following Specific Aims: (1) Define the epidemiology and burden of community- acquired and hospital-associated respiratory virus infections and compare clinical impact by viral species; (2) Improve the sensitivity and specificity of case definitions to identify hospital-associated respiratory virus cases by integrating clinical, epidemiologic, and molecular data; and (3) Determine the cost-effectiveness of increased respiratory virus screening and expanded infection control measures to reduce HA-RVI using mathematical models. The proposed administrative supplement will facilitate application of these aims to hospital-associated SARS-CoV-2 infection. The expected research outcomes of the proposed project are, 1) determination of the incidence and outcomes of hospital-associated SARS-CoV-2 infections; 2) improved identification of hospital-associated SARS-CoV-2 infections through integration of clinical, epidemiologic, and molecular data; and 3) quantification of the effects of COVID-19 response strategies in the hospital on the incidence of hospital-associated SARS-CoV-2. The proposed research is significant because it is expected that the outcomes of this work and future studies that build upon it, will inform ongoing response to the COVID-19 pandemic and future pandemics. This research is innovative both in its use of cross-disciplinary methodology that allows for new avenues of research.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2023 ( Subtotal = $24,243 )
2023	2023	MARSHFIELD CLINIC	1000 N OAK AVE	MARSHFIELD	WI	54449	WOOD	USA	Allergy and Infectious Diseases Research	002	5	12/2/2022	NON-COMPETING CONTINUATION	$106,212
2023	2022	MARSHFIELD CLINIC	1000 N OAK AVE	MARSHFIELD	WI	54449	WOOD	USA	Allergy and Infectious Diseases Research	001	4	11/9/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$2,628
2023	2021	REGENTS OF THE UNIVERSITY OF MICHIGAN	1109 GEDDES AVE, SUITE 3300	ANN ARBOR	MI	48109	WASHTENAW	USA	Allergy and Infectious Diseases Research	000	3	11/9/2022	NON-COMPETING CONTINUATION	-$2,628
2023	2021	REGENTS OF THE UNIVERSITY OF MICHIGAN	1109 GEDDES AVE, SUITE 3300	ANN ARBOR	MI	48109	WASHTENAW	USA	Allergy and Infectious Diseases Research	004	3	2/9/2023	SUPPLEMENT FOR EXPANSION	-$60,002
2023	2020	REGENTS OF THE UNIVERSITY OF MICHIGAN	1109 GEDDES AVE, SUITE 3300	ANN ARBOR	MI	48109	WASHTENAW	USA	Allergy and Infectious Diseases Research	003	2	2/9/2023	SUPPLEMENT FOR EXPANSION	-$21,967
														Subtotal = $24,243

Issue Date FY: 2022 ( Subtotal = $106,212 )
2022	2022	MARSHFIELD CLINIC	1000 N OAK AVE	MARSHFIELD	WI	54449	WOOD	USA	Allergy and Infectious Diseases Research	004	4	5/26/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$0
2022	2022	MARSHFIELD CLINIC	1000 N OAK AVE	MARSHFIELD	WI	54449	WOOD	USA	Allergy and Infectious Diseases Research	002	4	1/20/2022	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$106,212
2022	2021	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Allergy and Infectious Diseases Research	003	3	1/21/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2021	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Allergy and Infectious Diseases Research	000	3	1/20/2022	NON-COMPETING CONTINUATION	$0
2022	2020	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Allergy and Infectious Diseases Research	001	2	1/20/2022	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $106,212

Issue Date FY: 2021 ( Subtotal = $166,214 )
2021	2021	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Allergy and Infectious Diseases Research	002	3	5/13/2021	NON-COMPETING CONTINUATION	$0
2021	2021	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Allergy and Infectious Diseases Research	001	3	1/5/2021	SUPPLEMENT FOR EXPANSION	$60,002
2021	2021	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Allergy and Infectious Diseases Research	000	3	12/3/2020	NON-COMPETING CONTINUATION	$106,212
														Subtotal = $166,214

Issue Date FY: 2020 ( Subtotal = $149,204 )
2020	2020	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Allergy and Infectious Diseases Research	001	2	6/23/2020	SUPPLEMENT FOR EXPANSION	$42,992
2020	2020	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Allergy and Infectious Diseases Research	000	2	1/8/2020	NON-COMPETING CONTINUATION	$106,212
														Subtotal = $149,204

Issue Date FY: 2019 ( Subtotal = $106,212 )
2019	2019	REGENTS OF THE UNIVERSITY OF MICHIGAN	503 THOMPSON ST	ANN ARBOR	MI	48109	WASHTENAW	USA	Allergy and Infectious Diseases Research	000	1	1/2/2019	NEW	$106,212
														Subtotal = $106,212

Grand Total All Awards = $552,085

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Hospital-Associated Respiratory Virus Infections: Molecular Epidemiology, Clinical Outcomes, and Cost-Effectiveness of Interventions - COVID-19 Administrative Supplement

Award Number: K01AI141579

ORGANIZATION: NATIONAL INSTITUTE OF ALLERGY & INFECTIOUS DISEASES

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer