Friday, May 9, 2025 5/9/2025

Improving Family Cancer History Collection using Social Network, Human Centered Design, and Implementation Science Approaches

Award Number: K00CA253576
ORGANIZATION: NATIONAL CANCER INSTITUTE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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Improving Family Cancer History Collection using Social Network, Human Centered Design, and Implementation Science Approaches - PROJECT SUMMARY The research strategy and training plan included in this F99/K00 proposal will enhance the career development and research independence of Caitlin G. Allen, MPH. This research plan aims to advance knowledge of how to expand the reach and uptake of existing evidence-based genetics tools such as family cancer history (FCH) among underserved minority populations. FCH collection is a simple, proven way to identify individual's genetic risk for developing cancer that can encourage tailored cancer prevention and risk-stratified screening. Despite national efforts, FCH collection remains suboptimal with especially noteworthy disparities in collection among African American (AA) families. Ms. Allen's F99 research and training will focus on developing her skills in social network analysis to study individual and family network factors that contribute to poor knowledge of FCH. Ms. Allen has already completed two complementary dissertation studies that directly inform the proposed F99 research: 1) a systematic review of family health collection tools, and 2) development of a valid and reliable scale used to identify family network members that are highly likely to share FCH information. She will complete her dissertation research in the F99 phase of this award, which will involve: 1) 50 AA participants completing their FCH using a FCH collection tool (ItRunsInMyFamily), and 2) characterizing individual- and network-level factors that influence FCH collection by conducting personal network interviews using the Colored Eco-Genetic Relationship Map technique. To accomplish these aims, her F99 training objectives are to: 1) hone professional skills in grantsmanship, academic writing, and research dissemination, 2) develop scientific independence by strengthening methodological and analytic skills in social network analysis and relevant research methods, and 3) identify a postdoctoral site and K00 mentor. Ms. Allen's F99 training plan is bolstered by strong support from an excellent mentorship team at the Rollins School of Public Health and the research infrastructure at Emory University, creating an optimal training environment. Ms. Allen's postdoctoral research (K00 phase) will expand upon F99 work by enhancing a FCH collection tool (ItRunsInMyFamily) through human centered design approaches and implementing this tool in community-based clinical settings. Her training goals aligned with this phase of research includes: 1) building knowledge in human centered design and health technology assessment, 2) becoming an expert in implementation science, and 3) enhancing professional and research skills to prepare for an academic research position. Collectively, the integrated research plan and training goals are critical to establishing a successful, innovative, and meaningful academic career focused on extending cancer-specific genetics discoveries to marginalized and underrepresented populations by supporting evidence-based solutions such as FCH to improve cancer prevention and early-detection.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = -$110,533 )
2025	2024	THE MEDICAL UNIVERSITY OF SOUTH CAROLINA	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Cancer Cause and Prevention Research	001	5	2/11/2025	NON-COMPETING CONTINUATION	-$105,909
2025	2023	THE MEDICAL UNIVERSITY OF SOUTH CAROLINA	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Cancer Cause and Prevention Research	000	4	2/11/2025	NON-COMPETING CONTINUATION	-$4,624
														Subtotal = -$110,533

Issue Date FY: 2024 ( Subtotal = $105,909 )
2024	2024	THE MEDICAL UNIVERSITY OF SOUTH CAROLINA	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Cancer Cause and Prevention Research	001	5	7/8/2024	NON-COMPETING CONTINUATION	$0
2024	2024	THE MEDICAL UNIVERSITY OF SOUTH CAROLINA	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Cancer Cause and Prevention Research	000	5	5/6/2024	NON-COMPETING CONTINUATION	$105,909
2024	2024	THE MEDICAL UNIVERSITY OF SOUTH CAROLINA	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Cancer Cause and Prevention Research	002	5	9/10/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $105,909

Issue Date FY: 2023 ( Subtotal = $101,062 )
2023	2023	MEDICAL UNIVERSITY OF SOUTH CAROLINA THE	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Cancer Cause and Prevention Research	000	4	5/9/2023	NON-COMPETING CONTINUATION	$101,062
														Subtotal = $101,062

Issue Date FY: 2022 ( Subtotal = $96,215 )
2022	2022	MEDICAL UNIVERSITY OF SOUTH CAROLINA THE	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Cancer Cause and Prevention Research	002	3	6/24/2022	NON-COMPETING CONTINUATION	$96,215
2022	2021	MEDICAL UNIVERSITY OF SOUTH CAROLINA THE	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Cancer Cause and Prevention Research	001	2	3/15/2022	EXTENSION WITH OR WITHOUT FUNDS	$12,610
2022	2020	EMORY UNIVERSITY	201 DOWMAN DR	ATLANTA	GA	30322	DEKALB	USA	Cancer Cause and Prevention Research	000	1	3/15/2022	NEW	-$12,610
														Subtotal = $96,215

Issue Date FY: 2021 ( Subtotal = $92,988 )
2021	2021	MEDICAL UNIVERSITY OF SOUTH CAROLINA THE	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Cancer Cause and Prevention Research	001	2	5/19/2021	EXTENSION WITH OR WITHOUT FUNDS	$92,988
2021	2020	EMORY UNIVERSITY	201 DOWMAN DR	ATLANTA	GA	30322	DEKALB	USA	Cancer Cause and Prevention Research	000	1	5/6/2021	NEW	$0
														Subtotal = $92,988

Grand Total All Awards = $285,641

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Improving Family Cancer History Collection using Social Network, Human Centered Design, and Implementation Science Approaches

Award Number: K00CA253576

ORGANIZATION: NATIONAL CANCER INSTITUTE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: SCIENTIFIC/HEALTH RESEARCH (INCLUDES SURVEYS)

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