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 | Issue Date FY: 2025 ( Subtotal = $68,120,555 ) (Continued on the next page) |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R35GM146749 | Regulatory Mechanisms of Arginine Methylation | 000 | 4 | NIH | 5/14/2025 | $377,500 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | 90DPEM0006 | Quality employment outcomes throughout the work lifecycle: Application to persons with spinal cord injury, multiple sclerosis, and stroke. | 00 | 5 | ACL | 6/3/2025 | $499,694 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA261232 | Optimizing Tobacco Treatment Delivery for People Living with HIV | 000 | 5 | NIH | 2/17/2025 | $438,231 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01AG081807 | The Role of Pericytes in Brain Hypoperfusion in Alzheimer's Disease Development | 000 | 3 | NIH | 2/14/2025 | $558,631 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01DA054271 | Thalamostriatal Circuitry in Opioid Seeking | 000 | 4 | NIH | 3/3/2025 | $305,775 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01DA054271 | Thalamostriatal Circuitry in Opioid Seeking | 001 | 4 | NIH | 4/9/2025 | $33,975 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | U01AI184159 | A Phase II Controlled Trial of Allogeneic Mesenchymal Stromal Cells for the Treatment of Refractory Lupus (MiSLE) | 001 | 2 | NIH | 5/22/2025 | $1,459,720 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | UH3DA048507 | RTMS manipulates imbalanced drive-reward and executive control circuitry for smoking cessation | 000 | 4 | NIH | 2/28/2025 | $622,433 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | UH3DA048507 | RTMS manipulates imbalanced drive-reward and executive control circuitry for smoking cessation | 001 | 4 | NIH | 4/10/2025 | $69,159 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01DA059969 | Evaluating a tobacco harm reduction strategy among clients enrolled in substance use disorder treatment | 002 | 2 | NIH | 5/19/2025 | $625,247 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R35GM155451 | Exploring the complex interactions between gut microbes and mucus | 000 | 2 | NIH | 6/13/2025 | $377,500 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R35GM150843 | Regulation and Consequences of Cytochrome P450 2E1 | 000 | 3 | NIH | 6/17/2025 | $368,932 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | UG4LM013736 | Region 2 Regional Medical Library, NNLM | 000 | 5 | NIH | 6/23/2025 | $1,215,385 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01DA059854 | Impacts of drug abuse-mediated inflammatory perturbations on affinity maturation of anti-CD4 autoantibodies and poor immune reconstitution from ART in HIV | 001 | 2 | NIH | 5/12/2025 | $697,735 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R00CA279651 | Developing a communication support intervention for cancer caregivers in emerging and young adulthood | 000 | 3 | NIH | 6/17/2025 | $247,371 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA285926 | Targeting cytoplasmic SET oncoprotein by sphingolipid analog drugs for the induction of necroptosis to treat lung cancer | 000 | 2 | NIH | 5/22/2025 | $371,477 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01EY036519 | Assessment of the Complement Pathway in a RPE/choroid Tissue Chip | 000 | 2 | NIH | 5/23/2025 | $1,013,515 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA267101 | Overcoming chemoresistance in triple negative breast cancer | 001 | 5 | NIH | 6/2/2025 | $37,083 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA267101 | Overcoming chemoresistance in triple negative breast cancer | 000 | 5 | NIH | 11/8/2024 | $333,753 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | U01NS087748 | Stroke Trials Network National Data Management Center (NDMC) | 002 | 11 | NIH | 12/18/2024 | $1,280,497 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | F31HL172609 | The role of neonatal ROS in cardiomyocyte maturation and injury response | 000 | 2 | NIH | 12/31/2024 | $51,974 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA154663 | TGFbeta-regulated epithelial-mesenchymal transition (EMT) | 001 | 15 | NIH | 5/30/2025 | $37,372 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA154663 | TGFbeta-regulated epithelial-mesenchymal transition (EMT) | 000 | 15 | NIH | 12/9/2024 | $336,353 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | U24AA029968 | CORE 2/2: INIA Stress and Chronic Alcohol Interactions: CIE-Stress Mouse Brain Activity Mapping Core (BAMC) | 000 | 4 | NIH | 3/4/2025 | $360,136 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | U01AA014095 | 1/8: INIA Stress and Chronic Alcohol Interactions: Role of Dynorphin/KOR and Oxytocin Systems in Stress-Enhanced Alcohol Drinking, Relapse, and Impaired Behavioral Flexibility | 000 | 23 | NIH | 3/20/2025 | $407,700 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | K23MH123931 | Modeling and Modulating Mechanisms of Escape, Avoidance, and Approach in the Anxiety Disorder Spectrum | 000 | 5 | NIH | 2/13/2025 | $208,980 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01EY034514 | Opioid-Induced Epigenetic Mechanisms in Glaucoma | 000 | 3 | NIH | 1/23/2025 | $421,439 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA290842 | Randomized controlled trial of varenicline to treat tobacco and cannabis co-use. | 000 | 2 | NIH | 5/13/2025 | $598,901 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA259186 | A Randomized Controlled Trial to Evaluate the Survivorship Needs Assessment Planning Tool for Head and Neck Cancer Survivor-Caregiver Dyads | 001 | 4 | NIH | 6/4/2025 | $47,104 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA259186 | A Randomized Controlled Trial to Evaluate the Survivorship Needs Assessment Planning Tool for Head and Neck Cancer Survivor-Caregiver Dyads | 000 | 4 | NIH | 12/19/2024 | $423,944 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R35GM151021 | Determining the factors that impact single stranded DNA mutagenesis | 000 | 3 | NIH | 6/5/2025 | $377,500 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | K23DC019970 | CI Neural Mechanisms | 000 | 4 | NIH | 11/22/2024 | $190,739 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | K99DA058761 | Neurobiological mechanisms underlying changes in PTSD-like symptoms after cannabis use | 000 | 2 | NIH | 3/24/2025 | $194,551 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA264921 | Machine Learning to identify Biomarkers for Risk of Chronic Graft-Versus-Host Disease | 000 | 4 | NIH | 3/14/2025 | $693,916 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R25DE032525 | Raise Awareness In Students Early (RAISE) in Oral Biology Program | 000 | 2 | NIH | 3/4/2025 | $125,598 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | K23DA058077 | Development of a Novel Cannabis Brief Intervention for Frequently-Using Emerging Adults | 000 | 2 | NIH | 5/15/2025 | $205,360 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA266522 | Characterizing and targeting PRMT5 in autophagy for cancer treatment | 001 | 3 | NIH | 5/23/2025 | $34,542 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA266522 | Characterizing and targeting PRMT5 in autophagy for cancer treatment | 000 | 3 | NIH | 4/11/2025 | $310,871 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA276378 | Preclinical Development of the Novel Inhibitor of Apoptosis Proteins S2/IAPinh for Cancer Therapy | 004 | 4 | NIH | 5/22/2025 | $33,775 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | F31DK139736 | Elucidating the role of Myosin 5b in microvilli assembly and in the setting of inflammation | 000 | 2 | NIH | 2/25/2025 | $44,698 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01DA051650 | The influence of noradrenergic circuitry on prefrontal neuronal ensemble dynamics and cue-induced heroin seeking | 001 | 5 | NIH | 5/23/2025 | $36,965 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01DA051650 | The influence of noradrenergic circuitry on prefrontal neuronal ensemble dynamics and cue-induced heroin seeking | 000 | 5 | NIH | 2/26/2025 | $332,681 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | P30CA138313 | Medical University of South Carolina - Cancer Center Support Grant | 003 | 17 | NIH | 5/27/2025 | $2,176,322 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | U01AA029972 | 4/8: INIA Stress and Chronic Alcohol Interactions: Role of corticotropin-releasing factor in cortico- and thalamo-striatal pathways in regulating alcohol-stress interactions | 000 | 4 | NIH | 3/5/2025 | $402,417 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01DK113159 | A Molecular Approach to the Pathogenesis of Portal Hypertension | 000 | 6 | NIH | 2/20/2025 | $413,771 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R21DA058901 | Elucidating the Role of Cortical Astroglia in Heroin Seeking | 000 | 1 | NIH | 6/27/2025 | $415,250 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA282408 | Assessing Metabolically Reprogrammed and Purified CD19-CAR-T in NHL and CLL | 001 | 2 | NIH | 5/23/2025 | $53,279 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | R01CA282408 | Assessing Metabolically Reprogrammed and Purified CD19-CAR-T in NHL and CLL | 000 | 2 | NIH | 3/6/2025 | $479,506 |
| | 2025 | 2025 | THE MEDICAL UNIVERSITY OF SOUTH CAROLINA | 179 ASHLEY AVE | CHARLESTON | SC | 29425-8908 | CHARLESTON | USA | U01DA041093 | 13/21 ABCD-USA CONSORTIUM: RESEARCH PROJECT SITE AT MUSC | 002 | 9 | NIH | 4/9/2025 | $112,949 |
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