Sage Memorial Hospital’s (Sage) Tribal Opioid Response Program will serve the communities of Cornfields, Ganado, Kinlichee, Klagetoh, Greasewood Springs, Steamboat, and Wide Ruins, Arizona, which has a combined community population of more than 9,500 community members. Sage will also serve community members who reside outside of the service area, but choose to receive services from Sage. Through the implementation of MAT services, screening for opioid misuse, outreach training, and referrals to behavioral health services, Sage intends to serve over 4,800 individuals per year. The goal is to build a support system to identify individuals who are at risk for opioid and stimulant use disorder and guide them to treatment by taking proactive steps to prevent the increase in the number of opioid-related and methamphetamine cases in the service area. Sage intends to do that by first, creating standards of care procedures and recovery support services for those diagnosed with OUD/SUD so they are able to find a path to recovery, then providing a local source where patients can receive MAT services, and finally, developing prevention strategies that spread awareness and education. The objective is to (1) ensure at least four providers obtain DATA-waivers to administer and prescribe buprenorphine with the implementation of the Emergency Department Initiation of Office-Based Opioid Treatment, (2) make sure patients are screened utilizing the Opioid Risk Tool, and (3) provide training to staff and community members on the service delivery model, naloxone administration, and the risks and dangers of opioid misuse.