The Collaborative Care Initiative (CCI) enhances and coordinates behavioral health and primary care services for individuals with mental health and/or substance use disorders in community health centers and opioid treatment programs (OTPs), which also provide follow up care for referrals from emergency rooms after a drug overdose. By placing care coordinators, nurse care managers, psychiatrists and behavior specialists in the partnering Federally Qualified Health Centers (FQHCs) and OTPs, the initiative allows these programs to provide screening, diagnosis, prevention and treatment of behavioral health and medical conditions for their underserved populations. In accordance with the Four Quadrant Model of Clinical Integration, individuals with SUDs and/or mental health disorders will be assigned to the services that best meet their needs based on their level of medical and behavioral complexity/risk. Situated in two New Jersey counties with high number of drug overdoses, these programs will also be capable of receiving warm hand offs from local emergency rooms, where peer coaches and patient navigators are already stationed to engage those reversed after an opioid overdose and provide a warm handoff to the programs’ SUD services. The initiative increases the provision of substance use services, including medication assisted treatment, by taking advantage of the unused behavioral health treatment capacity of the FQHCs; these programs have provided few behavioral health services during a time when a critical need exists for the services, especially for those with opioid use disorders. Providing smoking cessation therapy is another component of these programs that has not been available. The CCI will also enable OTP clients to receive coordinated access to the primary care services available in the FQHCs, so that their co-morbid medical issues, including HIV and hepatitis C, can be addressed. By developing affiliations with one or more FQHCs, OTPs will ensure that their patients will receive treatment and preventative services by a consistent Collaborative Care Team that is working with their program staff. All FQHC and OTP admissions will be screened for behavioral health and medical need; based on current rates, this will total 5,158 admissions per year. Since an estimated 10% of FQHC admissions will need management by Collaborative Care Teams, while all of those at the OTP will need these teams’ services, a total of 1,198 individuals is expected to receive services from the teams in Year 1. The CCI will measure and track outcomes of the initiative, so that services and policies can be refined and improved. As state policy makers are currently examining how regulations and reimbursement for such services may have been barriers to integration efforts in the past, the hope is that the CCI will provide a sustainable integration model for the state moving forward.