The Community Opioid Intervention Prevention Program will develop partnerships that provide increased access to resources to assist in combatting the opioid epidemic in the American Indian and Alaska Natives (AIAN) community members in and around Ottawa County, Oklahoma. The purpose of the project is to reduce the burden of opioid use within the Modoc Nation by increasing regional access, awareness, and utilization of culturally appropriate practices that foster resiliency and encourage recovery activities for opioid misuse and opioid use disorder. The program will provide culturally appropriate prevention, intervention, treatment/medications for opioid use disorder (MAT/MOUD), recovery and aftercare services for opioid use disorders within the AIAN communities while developing strategies that align with the Department of Health and Humans Services Overdose Prevention Strategy. Due to historical trauma and limited access to services, the AIAN population has had inadequate culturally competent substance misuse resources, leading to a higher-than-average substance use rate and a rise in treatment needs. The COIP program will be managed by the Lost River Treatment Center. (LRTC) will partner with the Modoc Healing House to ensure adults and youth receive education, prevention, intervention, treatment, and aftercare services as well as increase harm reduction within the community. Throughout implementation, we aim to decrease annual use rates of opioid use and decrease the rates of those who report needing services but do not receive any. The program will be heavily informed by strategic partnerships and engagement with community members which will be imperative to its success and sustainability.