Official websites use .gov

A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS

A lock ( 🔒 ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Need Help

Defining Cognitive Mechanisms of Upper Limb Motor Recovery After Stroke

Award Number: F31NS149736
ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS
PERIOD OF PERFORMANCE START DATE: 11/01/2026
PERIOD OF PERFORMANCE END DATE: 10/31/2027

Group Awards By:

View Award Description

Defining Cognitive Mechanisms of Upper Limb Motor Recovery After Stroke - Project Summary/Abstract Arm and hand impairments are among the most common and disabling outcomes of stroke, contributing to long-term loss of independence. Although motor outcomes are often linked to damage in descending motor pathways such as the corticospinal tract, substantial variability in recovery remains unexplained. This project investigates how specific cognitive processes account for meaningful variance in upper limb motor outcomes beyond motor system injury. The goal is to identify which cognitive functions influence upper limb motor recovery after stroke and whether they can predict responsiveness to rehabilitation. To achieve this, the project will leverage an ongoing NIH- funded clinical trial of a six-week motor rehabilitation intervention in adults with subacute stroke. Participants will complete detailed behavioral testing and structural MRI assessments before and after intervention. The study protocol will be expanded to include a targeted cognitive battery focused on attention control, executive function, working memory, and processing speed. Aim 1 will test which cognitive functions best explain variance in upper limb motor performance at baseline. Aim 2 will test which cognitive functions best predict upper limb motor gains after rehabilitation. Aim 3 will use lesion symptom and network mapping to determine whether structural damage or disconnection in attention-related brain regions predicts motor outcomes. Together, these approaches will clarify how specific cognitive functions contribute to recovery and provide mechanistic targets for future interventions. This work aligns with the NIH mission to reduce disability and enhance quality of life through improved understanding of brain behavior relationships and more personalized rehabilitation strategies.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $40,946 )
2026	2026	TRUSTEES OF TUFTS COLLEGE	80 GEORGE ST	MEDFORD	MA	02155	MIDDLESEX	USA	Extramural Research Programs in the Neurosciences and Neurological Disorders	000	1	5/5/2026	NEW	$40,946
														Subtotal = $40,946

Grand Total All Awards = $40,946

Top

All Categories

About

Search

Reports

Data Submission

Award Information

Defining Cognitive Mechanisms of Upper Limb Motor Recovery After Stroke

Award Number: F31NS149736

ORGANIZATION: NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS

PERIOD OF PERFORMANCE START DATE: 11/01/2026

PERIOD OF PERFORMANCE END DATE: 10/31/2027

Federal Websites

Department of Health & Human Services

HHS Operating Divisions

HHS Staff Divisions

Download A Document Viewer