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Understanding How Children with Hemiparetic Cerebral Palsy Anticipate Gait

Award Number: F31HD102192
ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS
PERIOD OF PERFORMANCE START DATE: 12/10/2020
PERIOD OF PERFORMANCE END DATE: 04/09/2023

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Understanding How Children with Hemiparetic Cerebral Palsy Anticipate Gait - PROJECT SUMMARY/ABSTRACT Of all children in the US born with Cerebral Palsy (CP), 30-40% of them will be diagnosed with Hemiparetic CP (HCP), presenting with one side of the body being weaker than the other. The resulting asymmetries impede the ability of children with HCP to distribute weight evenly between their lower limbs. This, often, contributes to poor postural control and `favoring' of their uninvolved side (increased load on the uninvolved leg) during balance and gait. While many studies have examined gait and balance, our project serves as a foundational first step toward understanding how gait and balance influence one another. We're proposing a prospective, 40 participant (20 children with HCP and 20 typically developing (TD) children) one-visit study to locate and track the center of pressure (COP) during standing and walking tasks. This work seeks to determine the impact of gait anticipation (GA, i.e., expectation of initiating a step) on balance and load symmetry during quiet standing for children with HCP in comparison to TD peers. This aim allows us to fill the gap in knowledge concerning the relationship between GA and quiet standing balance. Completion of this will define for the first time the impact of load symmetry on balance for children with HCP. This work will also determine the impact of changing stance limb (dominant/non-dominant) on COP displacement and reaction time during gait initiation (GI) in children with HCP when compared with TD peers. While there is a clear difference in ability between limbs (especially for children with HCP), no one has attempted to quantify or comparatively analyze these differences. Assessing the ability of each limb to be the leading limb during GI provides a framework for evaluating how each limb performs when completing other daily activities, such as climbing stairs or stepping over obstacles. We can apply our findings toward revealing rehabilitation targets that not only focus on strengthening the more involved side, but also improve bilateral ability.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY	300 TURNER ST NW	BLACKSBURG	VA	24060	MONTGOMERY	USA	Child Health and Human Development Extramural Research	000	3	2/26/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $20,328 )
2023	2023	VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY	300 TURNER ST NW	BLACKSBURG	VA	24060	MONTGOMERY	USA	Child Health and Human Development Extramural Research	000	3	12/2/2022	NON-COMPETING CONTINUATION	$20,014
2023	2023	VIRGINIA POLYTECHNIC INSTITUTE & STATE UNIVERSITY	300 TURNER ST NW	BLACKSBURG	VA	24060	MONTGOMERY	USA	Child Health and Human Development Extramural Research	001	3	2/7/2023	NON-COMPETING CONTINUATION	$314
														Subtotal = $20,328

Issue Date FY: 2022 ( Subtotal = $40,516 )
2022	2022	VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY	300 TURNER ST NW STE 4200	BLACKSBURG	VA	24061	MONTGOMERY	USA	Child Health and Human Development Extramural Research	001	2	4/22/2022	NON-COMPETING CONTINUATION	$717
2022	2022	VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY	300 TURNER ST NW STE 4200	BLACKSBURG	VA	24061	MONTGOMERY	USA	Child Health and Human Development Extramural Research	000	2	12/1/2021	NON-COMPETING CONTINUATION	$39,800
2022	2022	VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY	300 TURNER ST NW STE 4200	BLACKSBURG	VA	24061	MONTGOMERY	USA	Child Health and Human Development Extramural Research	002	2	6/23/2022	NON-COMPETING CONTINUATION	-$1
														Subtotal = $40,516

Issue Date FY: 2021 ( Subtotal = $39,800 )
2021	2021	VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY	300 TURNER ST NW STE 4200	BLACKSBURG	VA	24061	MONTGOMERY	USA	Child Health and Human Development Extramural Research	002	1	2/12/2021	NEW	$516
2021	2021	VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY	300 TURNER ST NW STE 4200	BLACKSBURG	VA	24061	MONTGOMERY	USA	Child Health and Human Development Extramural Research	000	1	11/30/2020	NEW	$39,284
2021	2021	VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY	300 TURNER ST NW STE 4200	BLACKSBURG	VA	24061	MONTGOMERY	USA	Child Health and Human Development Extramural Research	001	1	11/30/2020	NEW	$0
														Subtotal = $39,800

Grand Total All Awards = $100,644

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Understanding How Children with Hemiparetic Cerebral Palsy Anticipate Gait

Award Number: F31HD102192

ORGANIZATION: NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS

PERIOD OF PERFORMANCE START DATE: 12/10/2020

PERIOD OF PERFORMANCE END DATE: 04/09/2023

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