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Exploring Digital Platforms to Deliver Harm-Reduction Messaging to Enhance PrEP Adherence among Men who Misuse Alcohol: A Qualitative and Feasibility Study

Award Number: F31AA033001
ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS
PERIOD OF PERFORMANCE START DATE: 10/28/2026
PERIOD OF PERFORMANCE END DATE: 10/27/2027

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Exploring Digital Platforms to Deliver Harm-Reduction Messaging to Enhance PrEP Adherence among Men who Misuse Alcohol: A Qualitative and Feasibility Study - Men remain disproportionately impacted by HIV, and while pre-exposure prophylaxis (PrEP) is a proven prevention strategy, its effectiveness is undermined by nonadherence linked to alcohol and illicit drug use. Digital platforms, widely used by men to connect, are associated with higher alcohol and illicit drug use, presenting both challenges and opportunities for intervention. This study explores the intersection of alcohol misuse and PrEP adherence among men, with a focus on the influence of digital platforms. This study uses qualitative methods, specifically semi- structured interviews and thematic analysis, to:(1) examine how digital platforms impact alcohol and illicit drugs use behaviors and their effects on PrEP care continuum among men who misuse alcohol, and; (2) assess the acceptability and feasibility of leveraging these platforms to deliver harm-reduction messaging for alcohol and illicit drug use moderation management to improve PrEP adherence among men who misuse alcohol in Kentucky. Preliminary findings from the parent study “Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention”, (R01 AA030485) suggest men prefer harm- reduction approaches over abstinence for managing substance use, indicating potential receptivity to digital interventions. By exploring the feasibility and acceptability of integrating moderation management into messaging, this study aims to enhance PrEP adherence and inform the development of innovative, digitally delivered harm-reduction strategies tailored to this population. The findings will contribute to the future design of scalable, community-focused solutions to address overlapping public health challenges of alcohol misuse, illicit drug use, and HIV prevention.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $37,174 )
2026	2026	UNIVERSITY OF LOUISVILLE	2301 S 3RD ST	LOUISVILLE	KY	40208	JEFFERSON	USA	Alcohol Research Programs	000	1	5/4/2026	NEW	$37,174
														Subtotal = $37,174

Grand Total All Awards = $37,174

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Exploring Digital Platforms to Deliver Harm-Reduction Messaging to Enhance PrEP Adherence among Men who Misuse Alcohol: A Qualitative and Feasibility Study

Award Number: F31AA033001

ORGANIZATION: NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: FELLOWSHIP/SCHOLARSHIP/STUDENT LOANS

PERIOD OF PERFORMANCE START DATE: 10/28/2026

PERIOD OF PERFORMANCE END DATE: 10/27/2027

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