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 | Issue Date FY: 2025 ( Subtotal = $52,729,997 ) (Continued on the next page) |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01DE033702 | Pathoadaptive Modulation of Porphyromonas gingivalis Lipopolysaccharide Structure and Function | 000 | 2 | NIH | 7/25/2025 | $350,000 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01DE028883 | Topical Vitamin D and Periodontal Disease | 001 | 5 | NIH | 5/8/2025 | $40,256 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01DE028883 | Topical Vitamin D and Periodontal Disease | 000 | 5 | NIH | 3/7/2025 | $362,313 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01HL163818 | Systematic identification of cardiotoxic e-cigarette flavorants | 002 | 4 | NIH | 5/3/2025 | $714,300 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R25ES036039 | KEEP: Kentucky Environmental Education Pipeline, A program to retain a diverse and equitable scientific trainee pipeline | 000 | 2 | NIH | 1/6/2025 | $133,521 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01DK137790 | Definitive Evaluation of Gastric Dysrhythmia as a Disease Mechanism by a Novel Body Surface Gastric Mapping Technique | 000 | 2 | NIH | 7/22/2025 | $427,329 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R37CA234002 | Targeting 6-Phosphofructo-2-Kinase to increase efficacy of CDK4/6 Inhibitors | 000 | 6 | NIH | 7/23/2025 | $711,007 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | P20GM155899 | Louisville Clinical And Translational Research Center (LCTRC) | 000 | 2 | NIH | 7/29/2025 | $2,327,272 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01HL163003 | Mechanisms Contributing to Pregnancy-induced Cardiac Remodeling | 000 | 3 | NIH | 12/23/2024 | $479,561 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01AI172873 | Neutrophil Heterogeneity and Immunopathogenesis of COVID-19 ARDS | 000 | 3 | NIH | 12/13/2024 | $556,881 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01GM144349 | Linking the conformational landscape to enzymatic function through functional site distant mutations | 001 | 4 | NIH | 8/6/2025 | $32,415 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01GM144349 | Linking the conformational landscape to enzymatic function through functional site distant mutations | 000 | 4 | NIH | 12/16/2024 | $291,736 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01HL160927 | Fibroblast growth factor 1 prevents hyperlipidemia and atherosclerosis | 000 | 4 | NIH | 11/20/2024 | $479,176 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R21CA280141 | Lectikines for Immunotherapy against Ovarian Cancer | 001 | 2 | NIH | 6/4/2025 | $21,699 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R21CA280141 | Lectikines for Immunotherapy against Ovarian Cancer | 000 | 2 | NIH | 1/21/2025 | $195,288 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01AA031043 | An ethanol-sensitive, Bmp-PCP dependent pathway regulating endoderm cell behaviors | 000 | 2 | NIH | 5/12/2025 | $502,152 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R21CA290420 | Dietary fructose and NASH/HCC progression | 001 | 2 | NIH | 5/23/2025 | $18,290 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R21CA290420 | Dietary fructose and NASH/HCC progression | 000 | 2 | NIH | 3/14/2025 | $164,619 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01DC021445 | Neural Mechanisms of Ingestive Behavior | 000 | 2 | NIH | 6/13/2025 | $399,889 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01ES033531 | Vascular Toxicity of Benzene | 000 | 2 | NIH | 12/3/2024 | $664,616 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R00AA030627 | Restoration and preservation of hepatic cardiolipin levels promotes liver regeneration in AH | 001 | 4 | NIH | 8/14/2025 | $24,402 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R00AA030627 | Restoration and preservation of hepatic cardiolipin levels promotes liver regeneration in AH | 000 | 4 | NIH | 11/21/2024 | $219,621 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01NS141156 | Propriospinal Plasticity and Recovery After Incomplete Spinal Cord Injury. | 000 | 1 | NIH | 6/2/2025 | $462,296 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | M0154897 | Behavioral Health Workforce Education and Training Program | 00 | 1 | HRSA | 6/18/2025 | $600,000 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01NS129987 | The role of SOCE in microglia and secondary degeneration after SCI | 000 | 3 | NIH | 1/15/2025 | $414,535 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01DK133195 | Targeting urinary tract dysfunctions after spinal cord injury with epidural stimulation | 000 | 3 | NIH | 7/8/2025 | $349,999 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | P20GM125504 | Functional Microbiomics, Inflammation and Pathogenicity | 001 | 8 | NIH | 2/24/2025 | $2,112,750 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R35GM150599 | Bacterial ribosome heterogeneity and gene expression | 002 | 4 | NIH | 7/22/2025 | $386,490 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01AI178106 | Impact of inflammatory lipids on Yersinia pestis infection | 000 | 3 | NIH | 6/26/2025 | $723,955 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01CA279748 | Immunotherapeutic targeting of MIF-dependent chaperone activity | 000 | 3 | NIH | 3/14/2025 | $307,603 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01MH131633 | Longitudinal Personalized Dynamics Among Anorexia Nervosa Symptoms, Core Dimensions, and Physiology Predicting Suicide Risk | 000 | 3 | NIH | 7/7/2025 | $719,613 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01MH131633 | Longitudinal Personalized Dynamics Among Anorexia Nervosa Symptoms, Core Dimensions, and Physiology Predicting Suicide Risk | 000 | 3 | NIH | 7/7/2025 | $15,650 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01HL168198 | Role of the PEP cycle in cardiac fibrosis | 000 | 2 | NIH | 11/29/2024 | $523,760 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R21EY034674 | Detailed Molecular Structures of Tear Film Lipid Layer for Improved Treatment of Dry Eye Syndrome | 000 | 2 | NIH | 11/21/2024 | $183,077 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01CA272772 | Identifying and targeting a novel mechanism of chemotherapy-induced immunotherapeutic resistance in non-small cell lung cancer | 001 | 3 | NIH | 5/22/2025 | $35,304 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01CA272772 | Identifying and targeting a novel mechanism of chemotherapy-induced immunotherapeutic resistance in non-small cell lung cancer | 000 | 3 | NIH | 3/20/2025 | $317,740 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01CA305985 | Protecting the kidney from cisplatin induced injury and progression to chronic kidney disease | 000 | 1 | NIH | 6/12/2025 | $649,021 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | F31AA030934 | The role of MKP-1/MAPK in hepatocytes and macrophages in alcohol-associated liver disease pathogenesis | 000 | 3 | NIH | 7/25/2025 | $38,306 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01HL150581 | Epidural spinal cord stimulation and respiratory motor function after injury | 001 | 5 | NIH | 6/26/2025 | $74,615 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01HL150581 | Epidural spinal cord stimulation and respiratory motor function after injury | 000 | 5 | NIH | 4/18/2025 | $671,527 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01DE030939 | A T.fosythia-derived protease inhibitor in periodontal health and disease | 000 | 4 | NIH | 5/16/2025 | $539,501 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01DK131442 | The role of neutral ceramidase in intestinal fucosylation and liver steatosis and inflammation | 000 | 3 | NIH | 4/16/2025 | $398,430 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01NS131489 | Converting the glial scar to neurons repairs the injured neural circuits for functional recovery following spinal cord injury | 001 | 2 | NIH | 8/13/2025 | $348,693 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01AA029798 | Phosphodiesterase 4 mediated pathogenic mechanisms in alcohol associated liver disease | 001 | 5 | NIH | 8/14/2025 | $104,281 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R01AA029798 | Phosphodiesterase 4 mediated pathogenic mechanisms in alcohol associated liver disease | 000 | 5 | NIH | 7/31/2025 | $353,403 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | H7600536 | EARLY INTERVENTION SERVICES | 01 | 26 | HRSA | 8/4/2025 | $188,298 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | H7600536 | EARLY INTERVENTION SERVICES | 00 | 26 | HRSA | 4/28/2025 | $188,298 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R03DE033707 | Cobalamin in Porphyromonas gingivalis Pathogenicity | 001 | 2 | NIH | 5/9/2025 | $15,650 |
| | 2025 | 2025 | UNIVERSITY OF LOUISVILLE | 2301 S 3RD ST | LOUISVILLE | KY | 40208-1838 | JEFFERSON | USA | R03DE033707 | Cobalamin in Porphyromonas gingivalis Pathogenicity | 000 | 2 | NIH | 3/5/2025 | $140,850 |
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