We are proposing a 5 year training program entitled ““Training Program for Strengthening Research
Capacity in Non-Communicable Diseases in Vietnam.” Vietnam has been facing an increasing burden from
non-communicable diseases (NCDs) over the last several decades, with especially notable increases in the
morbidity and mortality from cardiovascular disease (CVD), cancer, chronic lung disease, and diabetes; CVD
now represents the leading cause of death in Vietnam, accounting for approximately one third of all deaths.
Despite the magnitude and impact of NCDs, research capacity in NCDs in Vietnam is still limited and faces
numerous challenges. Vietnam urgently needs to strengthen its research capacity in the clinical and population
health sciences and develop research training programs that emphasize innovative strategies for disease
prevention.
As a starting point to address this ongoing need, our multi-disciplinary team received support from the
NIH Fogarty Center to engage in an intensive needs assessment and planning process during the past year.
The proposed training programs and educational offerings, and the accompanying mentored research
experiences, flow from a broad-based and detailed data collection and synthesis that engaged faculty and
students at Hanoi Medical University (HMU) and key partners from the Vietnam Ministry of Health. The
proposed training program is built upon a robust and rapidly expanding program of extramurally funded
research, with joint leadership from Vietnam and University of Massachusetts Medical School (UMMS)
investigators. The planning process has also been critically informed by several currently NIH-funded UMMS
training programs including T32 and KL2. Our Specific Aims are to: Aim 1. Develop a research and training
program in Non-Communicable Diseases that fits Vietnam's needs and resources as articulated by the
Vietnam Ministry of Health: (a) Establish a new Postdoctoral Fellowship program that will equip early-stage
investigators to establish themselves as independent, extramurally funded scientists; (b) Establish a new
Clinical Research Scholars Training Program that will provide clinicians with the research tools necessary to
leverage their clinical training and experience to design and carry out high quality research studies that
address pressing problems in clinical and population health, with an emphasis on national policy relevance and
publication in international journals; (c) Based on models that have been successfully implemented at the
UMMS, develop new research methods courses that would be offered to non-degree and degree students and
would be made available to students, physicians, nurses, and clinical investigators. Aim 2. Establish a Center
of Excellence in Non-Communicable Diseases Research at HMU: (a) Building upon formal
recommendations issued by the Vietnamese Ministry of Health as part of the year-long planning process,
inaugurate the newly proposed Center of Excellence with strong institutional commitments of HMU and HMU
hospital; (b) Implement an administrative structure that will allow the center to provide easily accessible
resources for research methodology and data management, enable transdisciplinary relationships across
departments, institutes, centers, and the clinical system, and provide linkages and critical support for
longitudinal mentoring relationships among program trainees; (c) Solidify collaboration with the Vietnam
Ministry of Health to align the research agenda and training approach with contemporary needs in CVD
prevention and treatment to support the national implementation of evidence-based policy measures.
Our international multi-disciplinary team has expertise in designing and conducting clinical and
population-based research studies and in developing successful research training programs. Our team
includes high-ranking and accomplished scientists from the Vietnam Ministry of Health who are serving in
leadership roles as part of our current NIH funded work. For several currently NIH funded clinical trials, the
Ministry of Health has formally committed to sustaining newly developed and proven interventions as part of
the national public health infrastructure. The environment and resources offered by this proposal provide an
unprecedented opportunity to strengthen research capacity in NCD research with a measurable health impact
at the national level.