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Partnership for Research in Emerging Viral Infections-Sierra Leone (PREVSL)

Award Number: D43TW011248
ORGANIZATION: FOGARTY INTERNATIONAL CENTER
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 07/22/2019
PERIOD OF PERFORMANCE END DATE: 12/31/2028

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Partnership for Research in Emerging Viral Infections-Sierra Leone (PREVSL) - Project Summary/ Abstract: Our existing award titled: Partnership for Research in Emerging Viral Infections-Sierra Leone, (PREVSL) [pronounced “Prev Sil”] (currently in its fifth year) has successfully begun to lay the foundation for Sierra Leone led implementation science and clinical trial research in emerging infections through capacity strengthening activities that targeted both the Kenema Government Hospital (KGH), a long- standing international field research site for the Viral Hemorrhagic Fever research program, located in the country´s Eastern Province; and the College of Medicine and Allied Health Sciences (COMAHS) at University of Sierra Leone (USL) in the capital city of Freetown, the country’s only medical school. Emerging infections threaten the health of people, animals, and agriculture but our systems for surveillance and detection are limited. Emerging infections are defined as those that have recently appeared in a population or that previously existed but have recently increased in incidence or geographic scope, such as was seen with the recent Mpox outbreak. Africa, and in particular West Africa, has a disproportionate vulnerability to outbreaks due to the large number of zoonotic reservoirs, poor healthcare infrastructure, and the high number of endemic infectious diseases found there. In Sierra Leone alone, EVD, Lassa Fever, Crimean Congo Hemorrhagic Fever, Yellow Fever, Dengue, Chikungunya, Mpox, Influenza, and SARS-CoV-2 have all been identified there. In addition, bat populations common to Sierra Leone have been found to have Marburg virus. Finally, like much of Africa, Sierra Leone also has high rates of antimicrobial resistance. With the foundations established in Phase I of PREVSL now in place, we will shift the bulk of our focus in the renewal proposal towards COMAHS, ensuring it has the capacity to train the next generation of high quality biomedical and public health scientists AND that it maximizes its potential to be a major player in driving Sierra Leone´s infectious disease research agenda. We will do this while continuing to strengthen the KGH clinical research program as a training site for future COMAHS masters and doctoral student researchers and through the promotion of ongoing implementation science and clinical trial research in emerging infections from which trainees can attain practical and applied research skills and experiences. Our Specific Aims are to 1) Train four PhD level investigators from Sierra Leone in disciplines relevant to emerging infectious diseases and pandemic preparedness; 2) Reinforce institutional capacity and competitiveness of COMAHS as Sierra Leone´s premier academic health sciences research institution; and 3) Promote and expand the conduct of high-quality implementation science and clinical trial research in emerging infectious diseases and pandemic preparedness by continuing to capacitate the Kenema Government Hospital - clinical research program field site.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $297,169 )
2026	2026	THE ADMINISTRATORS OF TULANE EDUCATIONAL FUND	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	International Research and Research Training	001	9	2/25/2026	SUPPLEMENT FOR EXPANSION	$42,880
2026	2026	THE ADMINISTRATORS OF TULANE EDUCATIONAL FUND	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	International Research and Research Training	000	9	2/16/2026	NON-COMPETING CONTINUATION	$172,565
2026	2026	THE ADMINISTRATORS OF TULANE EDUCATIONAL FUND	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	International Research and Research Training	002	9	2/26/2026	SUPPLEMENT FOR EXPANSION	$81,724
														Subtotal = $297,169

Issue Date FY: 2025 ( Subtotal = $296,608 )
2025	2025	THE ADMINISTRATORS OF TULANE EDUCATIONAL FUND	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	International Research and Research Training	000	8	12/30/2024	NON-COMPETING CONTINUATION	$296,608
														Subtotal = $296,608

Issue Date FY: 2024 ( Subtotal = $373,807 )
2024	2024	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	International Research and Research Training	003	7	9/24/2024	COMPETING CONTINUATION	$72,208
2024	2024	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	International Research and Research Training	000	7	3/19/2024	COMPETING CONTINUATION	$301,599
2024	2024	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	International Research and Research Training	001	7	5/15/2024	COMPETING CONTINUATION	$0
2024	2024	ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND, THE	6823 SAINT CHARLES AVE	NEW ORLEANS	LA	70118	ORLEANS	USA	International Research and Research Training	002	7	6/13/2024	COMPETING CONTINUATION	$0
														Subtotal = $373,807

Grand Total All Awards = $967,584

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Partnership for Research in Emerging Viral Infections-Sierra Leone (PREVSL)

Award Number: D43TW011248

ORGANIZATION: FOGARTY INTERNATIONAL CENTER

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 07/22/2019

PERIOD OF PERFORMANCE END DATE: 12/31/2028

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