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Building Implementation Science Capacity at Makerere University to Strengthen the Response to the HIV/AIDS Epidemic in Uganda

Award Number: D43TW010037
ORGANIZATION: FOGARTY INTERNATIONAL CENTER
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 05/11/2015
PERIOD OF PERFORMANCE END DATE: 03/31/2026

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Building Implementation Science Capacity at Makerere University to Strengthen the Response to the HIV/AIDS Epidemic in Uganda - Project Summary While Uganda is close to achieving the 90-90-90 targets, more than 27% of Ugandans with HIV remain with a detectable viral load and the potential to substantially contribute to new infections. Uganda faces challenges with HIV care and prevention, in particular for men, youth and geographically mobile subpopulations that continue to fall short of viral suppression targets, putting them at risk for HIV complications, mortality, and onward HIV transmission. With the aging HIV population there is increasing burden of comorbidities such as non- communicable diseases (NCDs), and integration of NCD-HIV care is paramount to improve HIV outcomes. Implementation science (ImS) research capacity is needed to optimize the public health impact of efficacious interventions such as test-and-treat and pre-exposure prophylaxis (PrEP) for eligible populations. Building on existing partnerships between Makerere University (MU) and its affiliated HIV programs and the University of California, San Francisco (UCSF), we have established a pioneer ImS Research Training Program at MU focused on enhancing the cascade of HIV care. We have built a strong foundation for ImS in Uganda through training, integrating ImS as a field of study at MU and influencing HIV practices. We propose to continue the Program and focus the next period on creation of sustained growth of ImS research environment at MU and the application of ImS to bear on HIV research and service delivery on a larger scale in Uganda. The specific objectives of our research training program renewal application are to: 1) strengthen the scientific leadership and expertise needed for implementation science research by having increased focus on PHD training at MU; 2) expand the breadth of training in ImS implementation science research at MU; 3) optimize utilization of resources for training by leveraging the additional available resources in Uganda (including projects funded by the NIH, European and Developing Country Clinical Trials Partnership (EDCTP), President’s Emergency Plan for AIDS Relief (PEPFAR), and others; 4) strengthen trainee contributions to evidence-based decision-making related to HIV prevention, care and treatment services through regular interactions with policy makers and HIV program implementers; and 5) support the integration of ImS trainees into Ugandan academic, research, policy and HIV implementing institutions to: a) pursue independent scientific careers in ImS and b) strengthen use of ImS in HIV service delivery. The proposed ImS training program will build on our relationships with UCSF faculty to provide a longitudinal mentorship program based on monthly works-in-progress meetings (held virtually via online platforms). During our five-year program, we anticipate training Ugandan trainees as follows: 4 candidates in PhD and 10 candidates in master’s degree programs at MU, 40 candidates in a Post Graduate Diploma in Implementation science research and quality Improvement and 6 candidates in the UCSF Online Certificate in ImS program. 1|Page


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $398,554 )
2025	2025	MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES	CLINICAL RESEARCH BUILDING NEW MULAGO HILL ROAD	KAMPALA				UGA	International Research and Research Training	000	9	10/15/2024	SUPPLEMENT FOR EXPANSION	$100,000
2025	2025	MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES	CLINICAL RESEARCH BUILDING NEW MULAGO HILL ROAD	KAMPALA				UGA	International Research and Research Training	001	10	3/10/2025	NON-COMPETING CONTINUATION	$298,554
														Subtotal = $398,554

Issue Date FY: 2024 ( Subtotal = $299,721 )
2024	2024	MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES	CLINICAL RESEARCH BUILDING NEW MULAGO HILL ROAD	KAMPALA				UGA	International Research and Research Training	003	9	9/20/2024	SUPPLEMENT FOR EXPANSION	$100,000
2024	2024	MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES	CLINICAL RESEARCH BUILDING NEW MULAGO HILL ROAD	KAMPALA				UGA	International Research and Research Training	004	9	9/23/2024	NON-COMPETING CONTINUATION	-$100,000
2024	2024	MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES	CLINICAL RESEARCH BUILDING NEW MULAGO HILL ROAD	KAMPALA				UGA	International Research and Research Training	002	9	8/27/2024	NON-COMPETING CONTINUATION	$0
2024	2024	MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES	CLINICAL RESEARCH BUILDING NEW MULAGO HILL ROAD	KAMPALA				UGA	International Research and Research Training	001	9	3/27/2024	NON-COMPETING CONTINUATION	$299,721
2024	2023	MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES	CLINICAL RESEARCH BUILDING NEW MULAGO HILL ROAD	KAMPALA				UGA	International Research and Research Training	000	8	1/25/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $299,721

Issue Date FY: 2023 ( Subtotal = $298,028 )
2023	2023	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	CLINICAL RESEARCH BUILDING NEW MULAGO HILL ROAD	KAMPALA				UGA	International Research and Research Training	000	8	3/23/2023	NON-COMPETING CONTINUATION	$298,028
														Subtotal = $298,028

Issue Date FY: 2022 ( Subtotal = $398,087 )
2022	2022	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	CLINICAL RESEARCH BUILDING NEW MULAGO HILL ROAD	KAMPALA				UGA	International Research and Research Training	004	7	9/16/2022	SUPPLEMENT FOR EXPANSION	$100,000
2022	2022	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	CLINICAL RESEARCH BUILDING NEW MULAGO HILL ROAD	KAMPALA				UGA	International Research and Research Training	003	7	3/15/2022	NON-COMPETING CONTINUATION	$298,087
2022	2022	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	CLINICAL RESEARCH BUILDING NEW MULAGO HILL ROAD	KAMPALA				UGA	International Research and Research Training	005	7	9/27/2022	SUPPLEMENT FOR EXPANSION	$0
2022	2021	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	CLINICAL RESEARCH BUILDING NEW MULAGO HILL ROAD	KAMPALA				UGA	International Research and Research Training	002	6	10/30/2021	COMPETING CONTINUATION	$1
2022	2021	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	NEW MULAGO HOSPITAL COMPLEX	KAMPALA				UGA	International Research and Research Training	000	6	10/28/2021	SUPPLEMENT FOR EXPANSION	$0
2022	2019	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	CLINICAL RESEARCH BUILDING NEW MULAGO HILL ROAD	KAMPALA				UGA	International Research and Research Training	001	5	10/30/2021	NON-COMPETING CONTINUATION	-$1
														Subtotal = $398,087

Issue Date FY: 2021 ( Subtotal = $377,645 )
2021	2021	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	NEW MULAGO HOSPITAL COMPLEX	KAMPALA				UGA	International Research and Research Training	000	6	3/18/2021	COMPETING CONTINUATION	$299,573
2021	2021	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	NEW MULAGO HOSPITAL COMPLEX	KAMPALA				UGA	International Research and Research Training	002	6	8/18/2021	SUPPLEMENT FOR EXPANSION	$78,072
2021	2021	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	NEW MULAGO HOSPITAL COMPLEX	KAMPALA				UGA	International Research and Research Training	001	6	4/19/2021	COMPETING CONTINUATION	$0
														Subtotal = $377,645

Issue Date FY: 2019 ( Subtotal = $304,560 )
2019	2019	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	NEW MULAGO HOSPITAL COMPLEX	KAMPALA				UGA	International Research and Research Training	000	5	4/29/2019	NON-COMPETING CONTINUATION	$304,560
														Subtotal = $304,560

Issue Date FY: 2018 ( Subtotal = $304,560 )
2018	2018	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	NEW MULAGO HOSPITAL COMPLEX	KAMPALA				UGA	International Research and Research Training	000	4	4/30/2018	NON-COMPETING CONTINUATION	$304,560
														Subtotal = $304,560

Issue Date FY: 2017 ( Subtotal = $334,560 )
2017	2017	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	NEW MULAGO HOSPITAL COMPLEX	KAMPALA				UGA	International Research and Research Training	002	3	9/9/2017	SUPPLEMENT FOR EXPANSION	$30,000
2017	2017	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	NEW MULAGO HOSPITAL COMPLEX	KAMPALA				UGA	International Research and Research Training	001	3	5/26/2017	NON-COMPETING CONTINUATION	$152,278
2017	2017	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	NEW MULAGO HOSPITAL COMPLEX	KAMPALA				UGA	International Research and Research Training	003	3	9/13/2017	SUPPLEMENT FOR EXPANSION	$0
2017	2017	MAKERERE UNIVERSITY COLLEGE O F HEALTH SCIENCES	NEW MULAGO HOSPITAL COMPLEX	KAMPALA				UGA	International Research and Research Training	000	3	5/20/2017	NON-COMPETING CONTINUATION	$152,282
														Subtotal = $334,560

Issue Date FY: 2016 ( Subtotal = $304,560 )
2016	2016	MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES	1ST FL CLINICAL RESEARCH BLDG	KAMPALA				UGA	International Research and Research Training	000	2	5/23/2016	NON-COMPETING CONTINUATION	$304,560
														Subtotal = $304,560

Issue Date FY: 2015 ( Subtotal = $304,160 )
2015	2015	MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES	1ST FL CLINICAL RESEARCH BLDG	KAMPALA				UGA	International Research and Research Training	000	1	5/15/2015	NEW	$304,160
														Subtotal = $304,160

Grand Total All Awards = $3,324,435

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Building Implementation Science Capacity at Makerere University to Strengthen the Response to the HIV/AIDS Epidemic in Uganda

Award Number: D43TW010037

ORGANIZATION: FOGARTY INTERNATIONAL CENTER

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 05/11/2015

PERIOD OF PERFORMANCE END DATE: 03/31/2026

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