Monday, June 30, 2025 6/30/2025

Training in HIV Genomics, Treatment, and Cure Research in Botswana

Award Number: D43TW009610
ORGANIZATION: FOGARTY INTERNATIONAL CENTER
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 08/01/2013
PERIOD OF PERFORMANCE END DATE: 04/30/2028

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Training in HIV Genomics, Treatment, and Cure Research in Botswana - PROJECT ABSTRACT The goal of this proposal is to provide research training in HIV genomic, treatment, and cure research at the Botswana-Harvard AIDS Institute Partnership (BHP), building on advances in laboratory research and clinical trial infrastructure at BHP that support training opportunities in the most advanced HIV laboratory techniques and study designs in the region. The environment at BHP offers a host of research opportunities for trained researchers in Botswana, matching current research activities of the faculty mentors and key partners working at the Botswana site. BHP is a partnership is between the Harvard TH Chan School of Public Health and the Ministry of Health (MOH) in Botswana (and the University of Botswana), and the largest HIV/AIDS research organization in Botswana (and one of the largest in Africa). The long-term goals and objectives of this Fogarty training program are to continue training research leaders who can take responsibility for BHP within the next 5–10 years, and researchers who can become academic faculty at the University of Botswana (UB) and HIV experts at MOH. Botswana currently has the third-highest prevalence of HIV in the world for adults (21%), but has also had the highest rate of antiretroviral drug treatment (ART) for patients with HIV (over 90%), and BHP has led efforts to support the treatment program with cutting-edge research in resistance and other genomic work, supported by Fogarty trainees. This work is now extending into the realm of HIV cure research, and into the intersection between HIV and SARS-CoV-2; BHP is now an internationally recognized center for research to understand the relationship between new SARS-CoV-2 variant emergence and the HIV epidemic. The training faculty at Harvard and at BHP will focus their ongoing efforts on keeping Fogarty trainees at the forefront of genomics, treatment, and cure research and strengthening training opportunities that are not available elsewhere in the region. We have requested funds for 2 predoctoral and 3 postdoctoral positions each year. We estimate that we will train about 18 trainees over 5 years, allowing for multiple years for each PhD candidate and some postdoctoral fellows, and assuming several short-term trainees could fill a single annual training slot. Stipends will be based on current degrees and research experience. All trainees would have at least a BSc degree. We estimate that about half will be physicians with clinical experience. Some will be postdoctoral fellows who have PhD’s in a related area but no experience in HIV research. Each trainee will have a primary mentor. Selection of trainees is based on previous academic performance, references, experience, and assurance that the candidates will return to participate in HIV research in Botswana. The quality of the program will be monitored by a Training Advisory Committee composed of experts from the US and the southern African region. The success of the training program will be judged by the implementation of successful treatment research programs that involve trainees, numbers of trainee publications in high-impact journals, and relative increase in senior research positions at BHP, UB, and MOH held by former trainees.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $402,400 )
2025	2025	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	1033 MASSACHUSETTS AVE STE 3	CAMBRIDGE	MA	02138	MIDDLESEX	USA	International Research and Research Training	002	12	6/9/2025	SUPPLEMENT FOR EXPANSION	$0
2025	2025	THE BOTSWANA HARVARD HEALTH PARTNERSHIP	PRINCESS MARINA HOSPITAL PLOT 1836 NORTH RING R	BOTSWANA				BWA	International Research and Research Training	003	13	6/16/2025	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$302,400
2025	2025	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	000	12	10/15/2024	SUPPLEMENT FOR EXPANSION	$100,000
2025	2024	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	1033 MASSACHUSETTS AVE STE 3	CAMBRIDGE	MA	02138	MIDDLESEX	USA	International Research and Research Training	001	12	6/9/2025	NON-COMPETING CONTINUATION	$0
														Subtotal = $402,400

Issue Date FY: 2024 ( Subtotal = $302,400 )
2024	2024	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	005	12	9/23/2024	NON-COMPETING CONTINUATION	-$100,000
2024	2024	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	003	12	8/27/2024	NON-COMPETING CONTINUATION	$0
2024	2024	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	004	12	9/20/2024	SUPPLEMENT FOR EXPANSION	$100,000
2024	2024	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	002	12	4/24/2024	NON-COMPETING CONTINUATION	$302,400
2024	2023	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	001	11	3/14/2024	COMPETING CONTINUATION	$233,967
2024	2022	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	000	10	3/14/2024	NON-COMPETING CONTINUATION	-$233,967
														Subtotal = $302,400

Issue Date FY: 2023 ( Subtotal = $241,776 )
2023	2023	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	003	11	4/21/2023	COMPETING CONTINUATION	$0
2023	2023	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	002	11	3/29/2023	COMPETING CONTINUATION	$0
2023	2023	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	001	11	3/10/2023	COMPETING CONTINUATION	$304,400
2023	2016	HARVARD COLLEGE PRESIDENT & FELLOWS OF	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	000	4	10/1/2022	SUPPLEMENT FOR EXPANSION	-$62,624
														Subtotal = $241,776

Issue Date FY: 2022 ( Subtotal = $300,640 )
2022	2022	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	000	10	4/19/2022	NON-COMPETING CONTINUATION	$300,640
														Subtotal = $300,640

Issue Date FY: 2021 ( Subtotal = $378,712 )
2021	2021	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	001	9	8/17/2021	SUPPLEMENT FOR EXPANSION	$78,072
2021	2021	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	000	9	4/22/2021	NON-COMPETING CONTINUATION	$300,640
														Subtotal = $378,712

Issue Date FY: 2020 ( Subtotal = $300,640 )
2020	2020	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	000	8	5/8/2020	NON-COMPETING CONTINUATION	$300,640
														Subtotal = $300,640

Issue Date FY: 2019 ( Subtotal = $300,640 )
2019	2019	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	004	7	7/10/2019	NON-COMPETING CONTINUATION	$300,640
2019	2018	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	003	6	2/27/2019	COMPETING CONTINUATION	$19,328
2019	2018	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	001	6	2/24/2019	COMPETING CONTINUATION	$19,328
2019	2017	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	002	5	2/27/2019	NON-COMPETING CONTINUATION	-$19,328
2019	2017	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	000	5	2/24/2019	NON-COMPETING CONTINUATION	-$19,328
														Subtotal = $300,640

Issue Date FY: 2018 ( Subtotal = $300,640 )
2018	2018	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	001	6	6/4/2018	COMPETING CONTINUATION	$300,640
2018	2017	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	000	5	5/29/2018	NON-COMPETING CONTINUATION	$0
														Subtotal = $300,640

Issue Date FY: 2017 ( Subtotal = $272,376 )
2017	2017	PRESIDENT AND FELLOWS OF HARVARD COLLEGE	677 HUNTINGTON AVE	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	000	5	1/23/2017	NON-COMPETING CONTINUATION	$272,376
														Subtotal = $272,376

Issue Date FY: 2016 ( Subtotal = $379,865 )
2016	2016	HARVARD UNIVERSITY, SCHOOL OF PUBLIC HEALTH	55 SHATTUCK STREET	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	000	4	2/15/2016	EXTENSION WITH OR WITHOUT FUNDS	$272,376
2016	2016	HARVARD UNIVERSITY, SCHOOL OF PUBLIC HEALTH	55 SHATTUCK STREET	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	001	4	9/24/2016	SUPPLEMENT FOR EXPANSION	$107,489
														Subtotal = $379,865

Issue Date FY: 2015 ( Subtotal = $272,376 )
2015	2015	HARVARD UNIVERSITY, SCHOOL OF PUBLIC HEALTH	55 SHATTUCK STREET	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	000	3	2/26/2015	NON-COMPETING CONTINUATION	$272,376
														Subtotal = $272,376

Issue Date FY: 2014 ( Subtotal = $322,376 )
2014	2014	HARVARD UNIVERSITY, SCHOOL OF PUBLIC HEALTH	55 SHATTUCK STREET	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	001	2	9/8/2014	SUPPLEMENT FOR EXPANSION	$50,000
2014	2014	HARVARD UNIVERSITY, SCHOOL OF PUBLIC HEALTH	55 SHATTUCK STREET	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	000	2	2/23/2014	NON-COMPETING CONTINUATION	$272,376
														Subtotal = $322,376

Issue Date FY: 2013 ( Subtotal = $272,376 )
2013	2013	HARVARD UNIVERSITY, SCHOOL OF PUBLIC HEALTH	55 SHATTUCK STREET	BOSTON	MA	02115	SUFFOLK	USA	International Research and Research Training	000	1	7/26/2013	NEW	$272,376
														Subtotal = $272,376

Grand Total All Awards = $4,047,217

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Training in HIV Genomics, Treatment, and Cure Research in Botswana

Award Number: D43TW009610

ORGANIZATION: FOGARTY INTERNATIONAL CENTER

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 08/01/2013

PERIOD OF PERFORMANCE END DATE: 04/30/2028

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