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Emory-Georgia TB Research Training Program

Award Number: D43TW007124
ORGANIZATION: FOGARTY INTERNATIONAL CENTER
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 09/27/2004
PERIOD OF PERFORMANCE END DATE: 02/28/2027

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Emory-Georgia TB Research Training Program - Tuberculosis (TB) is the most lethal infectious disease in human history, and prior to the COVID-19 pandemic was the leading cause of death from a single infectious agent globally, exceeding HIV. The COVID-19 pandemic has disrupted global TB control and is predicted to result in further increases in TB morbidity and mortality. Globally, the highest rates of drug-resistant TB have been reported from Eastern Europe, including the country of Georgia and other former Soviet republics. To meet the ambitious WHO End TB Strategy goals for 2035, new tools are urgently needed, including new and better drugs, improved diagnostics and an effective vaccine, as well as better implementation of existing tools. A shortage of well-trained TB investigators in Georgia and globally remains a key barrier to achieving the End TB Strategy goals. This renewal D43 application for the Emory-Georgia TB Research Training Program (EGTB-RTP) represents a collaboration between Emory University in Atlanta, GA, USA, and the 2 public health institutions in Tbilisi, Georgia, responsible for TB diagnostics, treatment, research and control: the National Center for Tuberculosis and Lung Disease (NCTLD) [lead Georgian institution] and the National Center for Disease Control and Public Health (NCDC) as well as collaboration with the Georgian AIDS Center and Ivane Javakhishvili Tbilisi State University (TSU). Much progress has been achieved since the initial funding of the EGTB-RTP in developing TB research infrastructure in Georgia, which was non-existent 16 years ago. Our program has provided long-term research training to 31 Georgians over 16 years helping to establish an emerging critical mass of MD and PhD-level investigators. Trainees in the EGTB-RTP have been highly productive with 92 TB-related publications during the current 5-year cycle of funding. NCTLD TB-related research funding has increased from <$5,000 per year when the EGTB-RTP was initiated to currently >$3 million per year. A major focus of an additional 5-year cycle of funding is the full transition of the leadership, management, and coordination of the research training program to Georgian investigators to ensure sustainability. To facilitate this transition, we propose an MPI format: Henry M. Blumberg, MD at Emory (PI of the EGTB-RTP since its inception) and Nestani Tukvadze, MD, a former Fogarty trainee who is now Director of the Clinical TB Research Unit at NCTLD and a leader of TB research in Georgia. Specific Aims of this renewal application include: 1) Transition program leadership, management, and training to Georgian investigators; 2) Continue to build human capacity to conduct high quality internationally recognized TB-related research in Georgia, focusing on long-term didactic and mentored research training to 12 new Fogarty trainees with outstanding potential; 3) Enhance research capacity and sustainability by providing leadership, mentor, and team science training; and 4) Focus on TB translational research and training in particular areas of strength along the T1-T4 translational research spectrum as well as implementation science and the requisite training to translate research findings into public policy.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $202,158 )
2026	2026	EMORY UNIVERSITY	201 DOWMAN DR NE	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	20	3/1/2026	NON-COMPETING CONTINUATION	$202,158
														Subtotal = $202,158

Issue Date FY: 2025 ( Subtotal = $296,480 )
2025	2025	EMORY UNIVERSITY	201 DOWMAN DR NE	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	19	1/22/2025	NON-COMPETING CONTINUATION	$296,480
														Subtotal = $296,480

Issue Date FY: 2024 ( Subtotal = $296,480 )
2024	2024	EMORY UNIVERSITY	201 DOWMAN DR	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	18	2/19/2024	NON-COMPETING CONTINUATION	$296,480
2024	2024	EMORY UNIVERSITY	201 DOWMAN DR NE	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	001	18	7/11/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $296,480

Issue Date FY: 2023 ( Subtotal = $296,407 )
2023	2023	EMORY UNIVERSITY	201 DOWMAN DR	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	002	17	2/20/2023	NON-COMPETING CONTINUATION	$296,407
2023	2022	EMORY UNIVERSITY	201 DOWMAN DR	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	001	16	12/20/2022	COMPETING CONTINUATION	$46,286
2023	2020	EMORY UNIVERSITY	201 DOWMAN DR	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	15	12/20/2022	NON-COMPETING CONTINUATION	-$46,286
														Subtotal = $296,407

Issue Date FY: 2022 ( Subtotal = $298,082 )
2022	2022	EMORY UNIVERSITY	201 DOWMAN DR	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	003	16	4/25/2022	COMPETING CONTINUATION	$0
2022	2022	EMORY UNIVERSITY	201 DOWMAN DR	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	002	16	3/8/2022	COMPETING CONTINUATION	$298,082
2022	2020	EMORY UNIVERSITY	201 DOWMAN DR	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	15	12/21/2021	NON-COMPETING CONTINUATION	$0
2022	2020	EMORY UNIVERSITY	201 DOWMAN DR	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	001	15	3/2/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $298,082

Issue Date FY: 2020 ( Subtotal = $268,272 )
2020	2020	EMORY UNIVERSITY	1599 CLIFTON RD.	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	001	15	3/5/2020	NON-COMPETING CONTINUATION	$0
2020	2020	EMORY UNIVERSITY	1599 CLIFTON RD.	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	15	1/23/2020	NON-COMPETING CONTINUATION	$268,272
														Subtotal = $268,272

Issue Date FY: 2019 ( Subtotal = $0 )
2019	2018	EMORY UNIVERSITY	1599 CLIFTON RD.	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	14	2/13/2019	NON-COMPETING CONTINUATION	$0
														Subtotal = $0

Issue Date FY: 2018 ( Subtotal = $267,312 )
2018	2018	EMORY UNIVERSITY	1599 CLIFTON RD.	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	14	2/3/2018	NON-COMPETING CONTINUATION	$267,312
														Subtotal = $267,312

Issue Date FY: 2017 ( Subtotal = $267,672 )
2017	2017	EMORY UNIVERSITY	1599 CLIFTON RD.	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	13	1/18/2017	NON-COMPETING CONTINUATION	$267,672
														Subtotal = $267,672

Issue Date FY: 2016 ( Subtotal = $267,592 )
2016	2016	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	12	2/25/2016	NON-COMPETING CONTINUATION	$267,592
														Subtotal = $267,592

Issue Date FY: 2015 ( Subtotal = $266,184 )
2015	2015	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	001	11	5/1/2015	COMPETING CONTINUATION	$266,184
2015	2013	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	10	4/30/2015	NON-COMPETING CONTINUATION	$0
														Subtotal = $266,184

Issue Date FY: 2013 ( Subtotal = $185,687 )
2013	2013	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	10	7/4/2013	NON-COMPETING CONTINUATION	$185,687
														Subtotal = $185,687

Issue Date FY: 2012 ( Subtotal = $195,460 )
2012	2012	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	9	6/21/2012	NON-COMPETING CONTINUATION	$195,460
														Subtotal = $195,460

Issue Date FY: 2011 ( Subtotal = $195,461 )
2011	2011	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	8	6/16/2011	NON-COMPETING CONTINUATION	$195,461
														Subtotal = $195,461

Issue Date FY: 2010 ( Subtotal = $195,460 )
2010	2010	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	001	7	8/5/2010	NON-COMPETING CONTINUATION	$195,460
2010	2009	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	Trans-NIH Recovery Act Research Support	000	6	12/8/2009	SUPPLEMENT FOR EXPANSION	$0
														Subtotal = $195,460

Issue Date FY: 2009 ( Subtotal = $367,646 )
2009	2009	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	Trans-NIH Recovery Act Research Support	002	6	9/1/2009	SUPPLEMENT FOR EXPANSION	$172,186
2009	2009	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	6	7/15/2009	COMPETING CONTINUATION	$195,460
2009	2009	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	001	6	7/20/2009	COMPETING CONTINUATION	$0
														Subtotal = $367,646

Issue Date FY: 2008 ( Subtotal = $111,625 )
2008	2008	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	5	4/24/2008	NON-COMPETING CONTINUATION	$111,625
														Subtotal = $111,625

Issue Date FY: 2007 ( Subtotal = $111,625 )
2007	2007	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	4	3/29/2007	NON-COMPETING CONTINUATION	$111,625
														Subtotal = $111,625

Issue Date FY: 2006 ( Subtotal = $118,750 )
2006	2006	EMORY UNIVERSITY	1784 N DECATUR RD,S 530 NDBLDG	ATLANTA	GA	30322	DEKALB	USA	International Research and Research Training	000	3	3/31/2006	NON-COMPETING CONTINUATION	$118,750
														Subtotal = $118,750

Issue Date FY: 2005 ( Subtotal = $129,968 ) (Continued on the next page)
Grand Total All Awards = $4,463,321

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Emory-Georgia TB Research Training Program

Award Number: D43TW007124

ORGANIZATION: FOGARTY INTERNATIONAL CENTER

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 09/27/2004

PERIOD OF PERFORMANCE END DATE: 02/28/2027

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