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Training and Research on Severe Malarial Anemia

Award Number: D43TW005884
ORGANIZATION: FOGARTY INTERNATIONAL CENTER
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP
PERIOD OF PERFORMANCE START DATE: 04/22/2002
PERIOD OF PERFORMANCE END DATE: 02/28/2027

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Training and Research on Severe Malarial Anemia - PROJECT SUMMARY This proposal is the fourth renewal of our continuously funded Global Infectious Disease training grant that established the International Malaria Training and Research Program (IMTRP) in 2002 (PD/PI, D. Perkins). While a central theme of our research training platform has focused on severe childhood malaria, the IMTRP has progressively expanded to include additional leading infectious diseases in Kenya. Our training approach utilizes advanced scientific instruction in thematic core areas with general principles that can be applied to combat a multitude of infectious diseases. This strategy offers advantages for creating long-term capacity building to address the challenges presented by both ongoing and newly emerging high-burden infectious diseases. Based on current and future needs identified by our Kenyan partners, we propose advanced research training in: (1) Host-Pathogen Dynamics, (2) Therapeutic Discovery, and (3) Disease Modeling. Training will be provided to address the ongoing challenges of malaria and the emergent crisis due to COVID-19. The next phase of our activities will continue long-standing international partnerships between the University of New Mexico (UNM), Los Alamos National Laboratory (LANL), Masinde Muliro University of Science and Technology (MMUST), Kenya Medical Research Institute (KEMRI), and West African Centre for Cell Biology of Infectious Pathogens (WACCBIP, Ghana), along with a new partner, Kirinyaga University (KyU). During the current funding cycle, trainees were highly prolific in generating peer-reviewed manuscripts (32) and presenting at international meetings (61). Moving forward, we propose long-term training (12 months) in Kenya for junior faculty at our partner institutions, along with postdoctoral fellows, and doctoral students (4 per year in each category). The IMTRP has created a highly successful pipeline of diverse trainees to continue in these career development tracks towards independent investigator status. A competitively awarded re-entry grant will be provided each year to support junior faculty in this important transition. We also propose medium-term training for specialized mentoring in advanced methodologies (technical and data analytic) for 3-4 trainees per year (6 months) in the US (UNM and/or LANL) and for 2 trainees per year (2-3 months) at WACCBIP. Short-term, in-depth training (2- 3 days) will also be offered annually on specialized research methodologies in the thematic three training areas and requisite research competencies. The overall training paradigm will foster sustained establishment of independent researchers in Kenya. Expansion of our highly successful training program in the next phase is based on over $50M in annual funding for the multidisciplinary team assembled. The training platform will provide transfer of technology and expertise to address the challenges of malaria, COVID-19, and other high- burden infectious diseases in Kenya. Collectively, the overall approach will promote long-term capacity-building and sustainability by establishing a critical mass of Kenyan scientists with the knowledge and skill sets necessary to address the public health challenges facing their society.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2025 ( Subtotal = $280,435 )
2025	2025	UNIVERSITY OF NEW MEXICO	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	23	2/19/2025	NON-COMPETING CONTINUATION	$280,435
														Subtotal = $280,435

Issue Date FY: 2024 ( Subtotal = $280,420 )
2024	2024	UNIVERSITY OF NEW MEXICO	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	22	3/5/2024	NON-COMPETING CONTINUATION	$280,420
2024	2024	UNIVERSITY OF NEW MEXICO	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	001	22	7/11/2024	NON-COMPETING CONTINUATION	$0
														Subtotal = $280,420

Issue Date FY: 2023 ( Subtotal = $280,377 )
2023	2023	UNIVERSITY OF NEW MEXICO	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	002	21	4/6/2023	NON-COMPETING CONTINUATION	$280,377
2023	2022	UNIVERSITY OF NEW MEXICO	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	001	20	12/13/2022	COMPETING CONTINUATION	$34,415
2023	2021	UNIVERSITY OF NEW MEXICO	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	19	12/13/2022	NON-COMPETING CONTINUATION	-$34,415
														Subtotal = $280,377

Issue Date FY: 2022 ( Subtotal = $282,334 )
2022	2022	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	002	20	4/25/2022	COMPETING CONTINUATION	$0
2022	2022	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	001	20	4/14/2022	COMPETING CONTINUATION	$282,334
2022	2021	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	19	4/8/2022	NON-COMPETING CONTINUATION	$0
														Subtotal = $282,334

Issue Date FY: 2021 ( Subtotal = $268,184 )
2021	2021	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	19	3/10/2021	NON-COMPETING CONTINUATION	$268,184
														Subtotal = $268,184

Issue Date FY: 2020 ( Subtotal = $267,824 )
2020	2020	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	18	3/19/2020	NON-COMPETING CONTINUATION	$267,824
														Subtotal = $267,824

Issue Date FY: 2019 ( Subtotal = $267,968 )
2019	2019	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	17	3/1/2019	NON-COMPETING CONTINUATION	$267,968
														Subtotal = $267,968

Issue Date FY: 2018 ( Subtotal = $268,226 )
2018	2018	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	002	16	3/19/2018	NON-COMPETING CONTINUATION	$268,226
2018	2017	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	14	1/16/2018	NON-COMPETING CONTINUATION	-$2,453
2018	2017	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	001	15	1/16/2018	COMPETING CONTINUATION	$2,453
														Subtotal = $268,226

Issue Date FY: 2017 ( Subtotal = $513,152 )
2017	2017	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	14	1/28/2017	NON-COMPETING CONTINUATION	$242,882
2017	2017	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	001	14	8/22/2017	NON-COMPETING CONTINUATION	$0
2017	2017	UNIVERSITY OF NEW MEXICO	2500 MARBLE DR NE	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	002	15	8/23/2017	COMPETING CONTINUATION	$270,270
														Subtotal = $513,152

Issue Date FY: 2016 ( Subtotal = $242,882 )
2016	2016	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	13	2/18/2016	EXTENSION WITH OR WITHOUT FUNDS	$242,882
														Subtotal = $242,882

Issue Date FY: 2015 ( Subtotal = $242,882 )
2015	2015	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	12	2/26/2015	NON-COMPETING CONTINUATION	$242,882
														Subtotal = $242,882

Issue Date FY: 2014 ( Subtotal = $242,882 )
2014	2014	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	11	3/1/2014	NON-COMPETING CONTINUATION	$242,882
														Subtotal = $242,882

Issue Date FY: 2013 ( Subtotal = $216,242 )
2013	2013	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	002	10	7/4/2013	COMPETING CONTINUATION	$216,242
2013	2011	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	9	3/14/2013	NON-COMPETING CONTINUATION	$0
2013	2011	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	001	9	7/1/2013	NON-COMPETING CONTINUATION	$0
														Subtotal = $216,242

Issue Date FY: 2011 ( Subtotal = $258,684 )
2011	2011	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	001	9	9/12/2011	SUPPLEMENT FOR EXPANSION	$129,342
2011	2011	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	9	3/25/2011	NON-COMPETING CONTINUATION	$129,342
														Subtotal = $258,684

Issue Date FY: 2010 ( Subtotal = $129,342 )
2010	2010	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	8	3/30/2010	NON-COMPETING CONTINUATION	$129,342
														Subtotal = $129,342

Issue Date FY: 2009 ( Subtotal = $129,342 )
2009	2009	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	7	3/13/2009	NON-COMPETING CONTINUATION	$129,342
														Subtotal = $129,342

Issue Date FY: 2008 ( Subtotal = $141,717 )
2008	2008	UNIVERSITY OF NEW MEXICO (THE)	1 UNIVERSITY OF NEW MEXICO	ALBUQUERQUE	NM	87131	BERNALILLO	USA	International Research and Research Training	000	6	9/11/2008	CHANGE OF GRANTEE / TRAINING INSTITUTION / AWARDING INSTITUTION	$141,717
														Subtotal = $141,717

Issue Date FY: 2007 ( Subtotal = $129,342 )
2007	2007	UNIVERSITY OF PITTSBURGH	FIFTH & BIGELOW BOULEVARD	PITTSBURGH	PA	15213	ALLEGHENY	USA	International Research and Research Training	000	5	8/7/2007	COMPETING CONTINUATION	$129,342
														Subtotal = $129,342

Issue Date FY: 2005 ( Subtotal = $98,291 )
2005	2005	UNIVERSITY OF PITTSBURGH	FIFTH & BIGELOW BOULEVARD	PITTSBURGH	PA	15213	ALLEGHENY	USA	International Research and Research Training	000	4	3/31/2005	NON-COMPETING CONTINUATION	$98,291
														Subtotal = $98,291

Grand Total All Awards = $4,951,181

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Training and Research on Severe Malarial Anemia

Award Number: D43TW005884

ORGANIZATION: FOGARTY INTERNATIONAL CENTER

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: TRAINING/TRAINEESHIP

PERIOD OF PERFORMANCE START DATE: 04/22/2002

PERIOD OF PERFORMANCE END DATE: 02/28/2027

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