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BRF: Biomedical Research Facilities Construction to Extend the Capabilities of the Kentucky Center of Precision Medicine

Award Number: C06OD042701
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: CONSTRUCTION
PERIOD OF PERFORMANCE START DATE: 09/18/2026
PERIOD OF PERFORMANCE END DATE: 12/31/2029

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BRF: Biomedical Research Facilities Construction to Extend the Capabilities of the Kentucky Center of Precision Medicine - PROJECT SUMMARY/ABSTRACT: The University of Louisville (UofL) is an Institution of Emerging Excellence (IEE) and one of 23 states designated by the National Institutes of Health (NIH) as an Institutional Development Award (IDeA) state, serving the research and healthcare needs of rural, medically underserved communities. As part of the IDeA state program, UofL is the recipient of three concurrent (and multiple past) NIH NIGMS funded Centers of Biomedical Research Excellence (CoBRE) projects to target local and regional health crises in Kentucky and Appalachia, is the lead institution for an IDeA Network of Biomedical Research Excellence (INBRE), and is the recipient of an IDeA Center of Translational Research program (CTR-D). The overarching goal of these grants is to improve infrastructure serving the needs of the Commonwealth of Kentucky investigators, with the goal of accelerating critical biomedical research discoveries and improving overall health outcomes. In 2025 UofL had a federal grant portfolio exceeding $95,000,000, but there remain workflow barriers that limit the translational potential of the work being performed by these exceptional programs that slows the direct impact they have on clinical care. UofL is requesting $8,000,000 to renovate the tenth floor of the A-Tower Research Building to expand the construction and capabilities of the newly founded Kentucky Center of Precision Medicine, a shared- use facility designed to support collaborative, investigator-driven technology development integrated with a deliberate implementation science pipeline connecting molecular discovery to clinical evaluation. The KCPM will focus on projects within four scientific pillars that are both UofL areas of strength and where there is need for improvement in prevention, innovative diagnostics, and novel treatment paradigms, including: (i) chronic disease and inflammation; (ii) environmental health; (iii) rare childhood disease, and (iv) cancer. The KCPM will also prioritize the development of new approach methodologies (NAMs) to enable and support ongoing human-centric projects across campus. The KCPM will support long-term institutional strategic plans and provide long-term modern improvements to our research infrastructure, serving as a base for the development and application of cutting-edge multiomics and computational biology supporting a broad range of investigators and their research efforts locally, regionally, and nationally. The discoveries that will be made at the KCPM have tremendous potential to improve health outcomes across the Commonwealth of Kentucky and beyond.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $8,000,000 )
2026	2026	UNIVERSITY OF LOUISVILLE	2301 S 3RD ST	LOUISVILLE	KY	40208	JEFFERSON	USA	Construction Support	000	1	9/17/2026	NEW	$8,000,000
														Subtotal = $8,000,000

Grand Total All Awards = $8,000,000

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BRF: Biomedical Research Facilities Construction to Extend the Capabilities of the Kentucky Center of Precision Medicine

Award Number: C06OD042701

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: CONSTRUCTION

PERIOD OF PERFORMANCE START DATE: 09/18/2026

PERIOD OF PERFORMANCE END DATE: 12/31/2029

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