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Clinical Research Center for REstoration of NEural-based Function in the Real World (RENEW)

Award Number: C06OD036020
ORGANIZATION: OFFICE OF THE DIRECTOR, NIH
OPDIV: NIH
AWARD CLASS: DISCRETIONARY
AWARD ACTIVITY TYPE: CONSTRUCTION
PERIOD OF PERFORMANCE START DATE: 09/14/2023
PERIOD OF PERFORMANCE END DATE: 06/30/2027

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Clinical Research Center for REstoration of NEural-based Function in the Real World (RENEW) - PROJECT SUMMARY / ABSTRACT The RENEW Center at the Medical University of South Carolina (MUSC) will be a unique clinical research facility dedicated to the restoration of neural-based function in the real world – the only such facility of its kind in South Carolina. The center goals are to: 1) Build out two floors of a soon-to-be constructed College of Health Professions (CHP) building in the heart of the MUSC campus. The RENEW Center upfit will be completed concurrently with the new CHP building construction and will meet Green Globes 2 certification. 2) Establish this specialized facility for advancing deep understanding of the neural circuits supporting physical and psychosocial function and their recovery after injury, disease, development, or aging to provide a mechanistic basis for interventions designed to impact functioning in the real world. This aligns directly with the MUSC Research Strategic Plan in three areas: Neural Circuits & Neuromodulation; Aging; Telehealth. 3) Develop an interdisciplinary research program that focuses on developing interventions that change function in the real world (vs. ideal lab settings) by gathering together neurosurgeons, neurologists, psychiatrists, neuropsychologists, PTs, speech therapists, OTs, exercise scientists, engineers, and others with a shared goal of decreasing disability statewide. As an Institution of Emerging Excellence, MUSC has dedicated considerable research and training resources over the past decade to meet the urgent needs of those living with stroke and other conditions, and to reducing health disparities in minority and rural populations. RENEW will build on these foundational investments to conduct neural circuit function research in ecologically valid environments that never before has been possible at MUSC. RENEW is organized into four research clusters: a Neural Function Cluster to understand, record from, and modulate neural circuits; a Physical Function Cluster to develop and study rehabilitation interventions; a Psychosocial Function Cluster to develop and study behavioral health interventions; and an Innovation & Technology Cluster to enable remote intervention, assessments, and monitoring in participants’ lived environments. A novel belief that guided RENEW Center development is that many current interventions lack durability and affect less change in functional status in the home than in the clinic because of a lack of integrated physical and behavioral interventions that account for how people change their behavior in their lived environment. The C06 will enable MUSC stakeholders across the university from three colleges and 16 departments to establish the RENEW Center with the infrastructure, labs, and human capital uniquely positioned to impact the physical and psychosocial functioning and independence of SC residents. RENEW will coalesce a critical mass of multidisciplinary physical rehabilitation and behavioral health investigators within a central, specialized facility and enhance their expertise in real world translational research. Without these unique resources, the positive and lasting functional impacts on SC residents in their lived environments would be dramatically reduced – especially for our sizeable rural and underserved populations.


Issue Date FY	Funding FY	Legal Entity Name	Legal Entity Address	Legal Entity City	Legal Entity State	Legal Entity Zip Code	Legal Entity COUNTY	Legal Entity COUNTRY	Assistance Listing	Award Code	Budget Year	Action Date	Action Type	Action Amount

Issue Date FY: 2026 ( Subtotal = $0 )
2026	2023	THE MEDICAL UNIVERSITY OF SOUTH CAROLINA	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Construction Support	000	1	5/27/2026	NEW	$0
														Subtotal = $0

Issue Date FY: 2025 ( Subtotal = $0 )
2025	2023	THE MEDICAL UNIVERSITY OF SOUTH CAROLINA	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Construction Support	002	1	7/11/2025	NEW	$0
2025	2023	THE MEDICAL UNIVERSITY OF SOUTH CAROLINA	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Construction Support	001	1	4/16/2025	NEW	$0
2025	2023	THE MEDICAL UNIVERSITY OF SOUTH CAROLINA	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Construction Support	000	1	11/15/2024	NEW	$0
														Subtotal = $0

Issue Date FY: 2024 ( Subtotal = $0 )
2024	2023	THE MEDICAL UNIVERSITY OF SOUTH CAROLINA	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Construction Support	000	1	11/15/2023	NEW	$0
														Subtotal = $0

Issue Date FY: 2023 ( Subtotal = $7,862,996 )
2023	2023	MEDICAL UNIVERSITY OF SOUTH CAROLINA THE	179 ASHLEY AVE	CHARLESTON	SC	29425	CHARLESTON	USA	Construction Support	000	1	9/14/2023	NEW	$7,862,996
														Subtotal = $7,862,996

Grand Total All Awards = $7,862,996

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Clinical Research Center for REstoration of NEural-based Function in the Real World (RENEW)

Award Number: C06OD036020

ORGANIZATION: OFFICE OF THE DIRECTOR, NIH

OPDIV: NIH

AWARD CLASS: DISCRETIONARY

AWARD ACTIVITY TYPE: CONSTRUCTION

PERIOD OF PERFORMANCE START DATE: 09/14/2023

PERIOD OF PERFORMANCE END DATE: 06/30/2027

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