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 | Issue Date FY: 2025 ( Subtotal = $56,248,195 ) (Continued on the next page) |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01HL168276 | A Novel role of Endothelial Breakpoint Cluster Region Protein in Vascular Health and Disease | 000 | 2 | NIH | 12/20/2024 | $478,071 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK133229 | TVP23B and Golgi Mediated Control of Intestinal Secretory Cells | 000 | 2 | NIH | 12/23/2024 | $567,626 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01HD103627 | Dissect the mechanisms underlying interspecies pluripotent stem cell competition | 000 | 4 | NIH | 12/16/2024 | $317,340 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | P01HL160487 | New Approaches to Reduce Residual Cardiovascular Risk | 000 | 4 | NIH | 12/18/2024 | $2,236,141 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA258602 | Cancer Resistant Mice | 000 | 4 | NIH | 11/18/2024 | $612,519 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK130892 | A human genetic variant ties defective hypothalamic development to obesity and diabetes | 000 | 4 | NIH | 12/18/2024 | $368,999 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK130959 | The Role of Gm4951 in Nonalcoholic Fatty Liver Disease | 000 | 4 | NIH | 12/17/2024 | $324,720 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01HL157281 | Transcriptional Control of Neonatal Heart Regeneration | 000 | 4 | NIH | 11/13/2024 | $508,532 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01HL161387 | The role of glycolysis and glucose oxidation in hematopoiesis | 000 | 4 | NIH | 1/17/2025 | $402,608 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK128166 | LIFR-alpha/JAK/STAT3-dependent Adipose Inflammation Contributes to Obesity-Associated NAFLD - Resubmissi | 000 | 4 | NIH | 2/20/2025 | $465,360 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK125713 | The role of ascorbate in myelopoiesis and infection | 000 | 5 | NIH | 3/4/2025 | $324,720 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS125250 | Behavioral and pharmacological manipulation of time cell activity in the human mesial temporal lobe | 000 | 4 | NIH | 11/14/2024 | $331,593 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AI153724 | Development of a vaccination platform for emerging flavivirus infections | 001 | 4 | NIH | 11/13/2024 | $459,768 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AI167920 | The Role of Pacs1-Wdr37 inLymphocyte Quiescence and Survival | 000 | 4 | NIH | 1/15/2025 | $397,700 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK128089 | Role of primary cilium-generated signaling in polycystic kidney disease | 000 | 4 | NIH | 11/22/2024 | $549,605 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | UG1DA020024 | NIDA Clinical Trials Network: Big South/West Node | 002 | 21 | NIH | 2/28/2025 | $0 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | UG1DA020024 | NIDA Clinical Trials Network: Big South/West Node | 001 | 21 | NIH | 1/17/2025 | $872,759 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01MD017529 | Polypill strategy for the evidence-based management of heart failure with reduced ejection fraction in an underserved patient population | 000 | 4 | NIH | 1/9/2025 | $661,713 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA274924 | A New Histone H3 Modification Regulates Epigenetic Programming and Gene Expression in Breast Cancer | 000 | 3 | NIH | 11/1/2024 | $384,949 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AI130020 | Defining Mechanisms for Parasite-Driven Effects on Gamma-Herpesvirus Latency | 000 | 7 | NIH | 1/17/2025 | $470,420 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA290297 | Molecular mechanisms and therapeutic principles of VISTA+ triple-negative breast cancers | 000 | 2 | NIH | 3/6/2025 | $414,810 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01EY034531 | The role of novel lincRNAs in regulating RGC survival after injury | 000 | 2 | NIH | 2/18/2025 | $410,000 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R37HD091856 | Transcription Factor Control of Neuronal Diversity | 000 | 9 | NIH | 1/8/2025 | $440,955 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R00CA252009 | Function of mesothelial cells in the tumor microenvironment of pancreatic ductal adenocarcinoma | 000 | 5 | NIH | 11/12/2024 | $224,100 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AG076529 | Lipid sensing through G protein geranylgeranylation | 000 | 4 | NIH | 1/27/2025 | $308,361 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R21CA288895 | Jumonji enzyme action in hepatocellular carcinoma onset | 000 | 2 | NIH | 1/14/2025 | $207,009 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R21AI180551 | Characterization of a Novel FACT-ETS-1 Antiviral Response Pathway and Identification of RNA Virus-Encoded Antagonists of this Host Response | 000 | 2 | NIH | 11/6/2024 | $198,850 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R21NS136951 | Determining the influence of cellular environments on a-synuclein fibril conformations | 000 | 2 | NIH | 2/13/2025 | $203,203 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AR083904 | Metabolic regulation of osteoclast differentiation and bone resorption | 000 | 1 | NIH | 1/30/2025 | $588,302 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01HL176788 | “Two-hit” model for lymphatic malformations. | 000 | 1 | NIH | 12/13/2024 | $508,436 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | F32HL178175 | Structure, Function and Drug Treatment of the Native Cardiac Sarcomere in Hypertrophic Cardiomyopathy | 000 | 1 | NIH | 1/27/2025 | $74,284 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R35GM156807 | Evolutionary Diversification of Cytoskeletal Proteins for Tissue-Specialized Roles | 000 | 1 | NIH | 12/19/2024 | $410,000 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA294133 | Genome-wide CRISPR screening identifies critical regulators controlling ccRCC lung metastasis | 000 | 1 | NIH | 12/11/2024 | $521,579 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K99CA283246 | Data-driven mechanistic models of morphology-controlled Ras oncogenic signaling | 000 | 1 | NIH | 2/20/2025 | $140,097 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA289260 | Metabolic mechanisms of glioma progression | 000 | 1 | NIH | 11/21/2024 | $682,596 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | F31GM154433 | Investigating the role of the RNA helicase F57B9.3 in translational regulation under conditions of lipid depletion | 001 | 1 | NIH | 11/7/2024 | $0 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | F31GM154433 | Investigating the role of the RNA helicase F57B9.3 in translational regulation under conditions of lipid depletion | 000 | 1 | NIH | 11/7/2024 | $40,127 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS139492 | Dissection of NTSR2/calcium channel signaling as a non-opioid spinal analgesic mechanism for the treatment of high impact chronic pain | 000 | 1 | NIH | 2/1/2025 | $664,772 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA286912 | Acquired Cross-Resistance through MYC Amplification in Small Cell Lung Cancer | 000 | 1 | NIH | 12/31/2024 | $642,429 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | F30DK142444 | Metabolic consequences of zonal defects in gluconeogenesis | 001 | 1 | NIH | 12/13/2024 | $0 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | F30DK142444 | Metabolic consequences of zonal defects in gluconeogenesis | 000 | 1 | NIH | 12/13/2024 | $39,959 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS137584 | Chromatin regulation of neuronal activity-induced enhancer priming and epigenetic memory | 000 | 1 | NIH | 2/28/2025 | $578,632 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K08CA290062 | Defining mechanisms of immunotherapy resistance and targeting TIGIT in hepatobiliary cancers | 000 | 1 | NIH | 1/29/2025 | $270,981 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AI187273 | Androgens modulate Staphylococcus aureus signaling and pathogenesis | 000 | 1 | NIH | 12/5/2024 | $643,614 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA289534 | Mechanisms and Models of Testis Specific Serine Kinase 6: A Novel Therapeutic Target in Colorectal Cancer | 000 | 1 | NIH | 12/4/2024 | $491,826 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA295762 | Overcoming mechanisms of PTPN1 driving therapy- and castration- resistant prostate cancer with novel theranostics | 000 | 1 | NIH | 11/29/2024 | $472,458 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA304065 | Developing Consensus on a Practical Framework for Variant Reclassification and Recontact | 001 | 1 | NIH | 1/15/2025 | $270,987 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA304065 | Developing Consensus on a Practical Framework for Variant Reclassification and Recontact | 001 | 1 | NIH | 1/15/2025 | -$270,987 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA304065 | Developing Consensus on a Practical Framework for Variant Reclassification and Recontact | 000 | 1 | NIH | 12/25/2024 | $541,972 |
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