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 | Issue Date FY: 2025 ( Subtotal = $160,263,865 ) (Continued on the next page) |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA276058 | Development of a RUVBL1/2 Inhibitor as a Radiosensitizer and Immune Stimulator for NSCLC | 000 | 3 | NIH | 4/28/2025 | $496,260 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA276058 | Development of a RUVBL1/2 Inhibitor as a Radiosensitizer and Immune Stimulator for NSCLC | 001 | 3 | NIH | 5/23/2025 | $55,139 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA276690 | Using artificial intelligence to discover spatial, genomic, and pathologic biomarkers to guide and augment immune checkpoint inhibitor therapy for gastric cancer | 001 | 2 | NIH | 5/22/2025 | $66,562 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA276690 | Using artificial intelligence to discover spatial, genomic, and pathologic biomarkers to guide and augment immune checkpoint inhibitor therapy for gastric cancer | 000 | 2 | NIH | 3/3/2025 | $599,055 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AG079094 | Role of KDM6B in Alzheimer’s disease related dementia | 001 | 3 | NIH | 6/10/2025 | $59,960 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AG079094 | Role of KDM6B in Alzheimer’s disease related dementia | 000 | 3 | NIH | 3/18/2025 | $674,557 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R21AI186020 | Alveolus on a chip model of non-tuberculous mycobacteria infection | 000 | 1 | NIH | 6/27/2025 | $451,000 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK099110 | White Adipose Tissue Physiology, Mitochondrial Function and Adiponectin | 001 | 12 | NIH | 6/12/2025 | $62,426 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK099110 | White Adipose Tissue Physiology, Mitochondrial Function and Adiponectin | 000 | 12 | NIH | 2/14/2025 | $561,840 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS137584 | Chromatin regulation of neuronal activity-induced enhancer priming and epigenetic memory | 000 | 1 | NIH | 2/28/2025 | $578,632 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AR078324 | Impacts of mechanosensation and matrix architecture on cell fate specification in traumatic heterotopic ossification | 001 | 5 | NIH | 4/17/2025 | $398,253 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K24HL146838 | Mentoring Patient-Oriented Research in Deep Lipid Phenotyping for Cardiovascular Disease | 002 | 7 | NIH | 5/7/2025 | $122,720 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AI190103 | Machine learning for identifying antigen-antibody interactions from massive sequencing data | 000 | 1 | NIH | 2/28/2025 | $667,013 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA258987 | Artificial Intelligence-Based Quality Assurance for Online Adaptive Radiotherapy | 001 | 4 | NIH | 5/22/2025 | $58,883 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA258987 | Artificial Intelligence-Based Quality Assurance for Online Adaptive Radiotherapy | 000 | 4 | NIH | 2/14/2025 | $529,956 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K08CA286756 | Uncovering therapeutic vulnerabilities in AML through mechanistic interrogation of MECOM activity | 003 | 3 | NIH | 5/21/2025 | $228,979 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R03MH134200 | Regulation of Topoisomerase 2 Beta by phosphorylation at the C-Terminal domain | 000 | 2 | NIH | 2/14/2025 | $69,700 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS121038 | Defining the impact of Frataxin point mutations on Friedreich's ataxia pathogenesis | 000 | 5 | NIH | 2/14/2025 | $369,000 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K08CA290062 | Defining mechanisms of immunotherapy resistance and targeting TIGIT in hepatobiliary cancers | 000 | 1 | NIH | 1/29/2025 | $270,981 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K02NS140483 | Role of HP1β-mediated heterochromatin organization in neurodevelopmental disorders: CBX1-related syndrome as a model | 000 | 1 | NIH | 1/31/2025 | $264,600 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AR085116 | Molecular Mechanisms of Myoblast Fusion | 000 | 1 | NIH | 2/27/2025 | $439,791 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01EY034531 | The role of novel lincRNAs in regulating RGC survival after injury | 000 | 2 | NIH | 2/18/2025 | $410,000 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01GM083122 | Structure and Function of Complexes that Regulate Ciliary Motility | 002 | 15 | NIH | 2/24/2025 | $460,506 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS139492 | Dissection of NTSR2/calcium channel signaling as a non-opioid spinal analgesic mechanism for the treatment of high impact chronic pain | 000 | 1 | NIH | 2/1/2025 | $664,772 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK125713 | The role of ascorbate in myelopoiesis and infection | 000 | 5 | NIH | 3/4/2025 | $324,720 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | F32HL178175 | Structure, Function and Drug Treatment of the Native Cardiac Sarcomere in Hypertrophic Cardiomyopathy | 000 | 1 | NIH | 1/27/2025 | $74,284 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS136363 | Analysis of ascending spinal pain circuits | 000 | 1 | NIH | 1/30/2025 | $453,104 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS107357 | Using deep brain stimulation of the parietal cortex to investigate the electrophysiology of human episodic memory | 003 | 8 | NIH | 6/27/2025 | $408,208 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS110853 | Cell Type Specific Genetic Manipulation to Dissect Cholinergic Interneuron Function and Plasticity in a Symptomatic Model of DYT1 Dystonia | 000 | 5 | NIH | 2/14/2025 | $454,382 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01MH134809 | Cellular resolution multi-omics of white matter tracts in developing human and non-human primate brain for cell atlases | 001 | 2 | NIH | 4/29/2025 | $1,331,545 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01MH134809 | Cellular resolution multi-omics of white matter tracts in developing human and non-human primate brain for cell atlases | 000 | 1 | NIH | 1/27/2025 | $30,447 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01HL176998 | Interpreting coding/non-coding variants for congenital heart disease through gene regulatory networks | 000 | 1 | NIH | 1/27/2025 | $802,762 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AR083904 | Metabolic regulation of osteoclast differentiation and bone resorption | 000 | 1 | NIH | 1/30/2025 | $588,302 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK078184 | Factors Controlling Metabolic Flux in the Liver | 004 | 16 | NIH | 5/15/2025 | $50,873 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK078184 | Factors Controlling Metabolic Flux in the Liver | 003 | 16 | NIH | 2/17/2025 | $457,855 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R35GM130358 | A solid state conceptualization of information transfer from gene to message to protein | 002 | 7 | NIH | 1/27/2025 | $479,700 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA260705 | Virtual Biopsy with Tissue-level Accuracy in Glioma | 001 | 5 | NIH | 5/23/2025 | $63,095 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA260705 | Virtual Biopsy with Tissue-level Accuracy in Glioma | 000 | 5 | NIH | 3/7/2025 | $567,878 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA289500 | Overcoming Therapy Resistance in SCLC | 001 | 2 | NIH | 5/22/2025 | $53,974 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA289500 | Overcoming Therapy Resistance in SCLC | 000 | 2 | NIH | 2/17/2025 | $485,789 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AG079513 | Characterization of how mRNA translation influences reproductive aging | 001 | 4 | NIH | 6/9/2025 | $26,896 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AG079513 | Characterization of how mRNA translation influences reproductive aging | 000 | 4 | NIH | 3/7/2025 | $302,580 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS123431 | Determining the mechanism of alpha-synuclein dependent innate immune responses in the brain | 002 | 4 | NIH | 4/29/2025 | $300,395 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01HD104970 | Optimization of Saturation Targets And Resuscitation Trial (OptiSTART) | 001 | 4 | NIH | 6/10/2025 | $512,109 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS137042 | Positron Emission Tomography (PET)-Derived Measurement of Brain Synaptic Vesicle Glycoprotein 2A (SV2A) – a Potential Biomarker in Patients with Essential Tremor | 000 | 1 | NIH | 3/14/2025 | $679,899 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01MH085923 | Molecular mechanisms of axon guidance and neural connectivity | 000 | 13 | NIH | 3/18/2025 | $515,708 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R21HD118402 | CRISPR interference to identify HSA21 genes reducing neurogenesis | 000 | 1 | NIH | 6/17/2025 | $451,000 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA273595 | Novel regulatory mechanisms and agonists of STING | 001 | 3 | NIH | 5/23/2025 | $68,060 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA273595 | Novel regulatory mechanisms and agonists of STING | 000 | 3 | NIH | 2/14/2025 | $612,538 |
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