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 | Issue Date FY: 2025 ( Subtotal = $160,954,647 ) (Continued on the next page) |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | U01NS132788 | Modeling and Mapping Human Action Regulation Networks | 000 | 3 | NIH | 6/27/2025 | $890,318 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | F30HL167629 | Unexpected mechanism underlying mislocalization of thrombocytopenia-associated ETV6 point mutation | 000 | 3 | NIH | 12/20/2024 | $46,839 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01HL168276 | A Novel role of Endothelial Breakpoint Cluster Region Protein in Vascular Health and Disease | 000 | 2 | NIH | 12/20/2024 | $478,071 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R00AR081897 | Comprehensive investigation of SP7 during the osteoblast-to-osteocyte transition | 002 | 4 | NIH | 5/15/2025 | $17,177 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R00AR081897 | Comprehensive investigation of SP7 during the osteoblast-to-osteocyte transition | 001 | 4 | NIH | 3/25/2025 | $220,847 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AI130020 | Defining Mechanisms for Parasite-Driven Effects on Gamma-Herpesvirus Latency | 000 | 7 | NIH | 1/17/2025 | $470,420 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AI153724 | Development of a vaccination platform for emerging flavivirus infections | 001 | 4 | NIH | 11/13/2024 | $459,768 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK128089 | Role of primary cilium-generated signaling in polycystic kidney disease | 000 | 4 | NIH | 11/22/2024 | $549,605 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AI167967 | Drug Target Discovery, Validation, and Prioritization for Schistosomiasis | 000 | 3 | NIH | 12/2/2024 | $819,288 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | F31NS132443 | The role of SMAD3 in gene networks underlying human brain activity | 000 | 2 | NIH | 1/1/2025 | $40,485 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA289435 | Mechanisms of Chromosome Shattering from Defective DNA Replication | 001 | 2 | NIH | 5/30/2025 | $44,146 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA289435 | Mechanisms of Chromosome Shattering from Defective DNA Replication | 000 | 2 | NIH | 3/3/2025 | $397,312 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA290297 | Molecular mechanisms and therapeutic principles of VISTA+ triple-negative breast cancers | 001 | 2 | NIH | 5/26/2025 | $46,089 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA290297 | Molecular mechanisms and therapeutic principles of VISTA+ triple-negative breast cancers | 000 | 2 | NIH | 3/6/2025 | $414,810 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK135556 | Mechanistic Connection between Interorganellar Communication and Obesity-associated Diseases | 000 | 3 | NIH | 2/27/2025 | $380,586 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | P30AG092752 | North Texas ADRC | 000 | 1 | NIH | 6/2/2025 | $4,663,946 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | UG1CA233302 | UT Southwestern NCI National Clinical Trials Network (NCTN) LAPS - Funded Extension Supplement YR6 | 000 | 6 | NIH | 3/3/2025 | $440,784 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K08DC019416 | Role of Fragile X Mental Retardation Protein on Gene Expression in Auditory Brainstem Development | 000 | 6 | NIH | 3/19/2025 | $182,253 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK128166 | LIFR-alpha/JAK/STAT3-dependent Adipose Inflammation Contributes to Obesity-Associated NAFLD - Resubmissi | 001 | 4 | NIH | 5/14/2025 | $51,706 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK128166 | LIFR-alpha/JAK/STAT3-dependent Adipose Inflammation Contributes to Obesity-Associated NAFLD - Resubmissi | 000 | 4 | NIH | 2/20/2025 | $465,360 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R21MH139200 | Phosphorylation-mediated regulation of Arc interactions with the AMPA receptor endocytic machinery | 000 | 1 | NIH | 3/19/2025 | $328,000 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AR078324 | Impacts of mechanosensation and matrix architecture on cell fate specification in traumatic heterotopic ossification | 001 | 5 | NIH | 4/17/2025 | $398,253 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R21AI186020 | Alveolus on a chip model of non-tuberculous mycobacteria infection | 000 | 1 | NIH | 6/27/2025 | $451,000 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AG079094 | Role of KDM6B in Alzheimer’s disease related dementia | 001 | 3 | NIH | 6/10/2025 | $59,960 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AG079094 | Role of KDM6B in Alzheimer’s disease related dementia | 000 | 3 | NIH | 3/18/2025 | $674,557 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA276690 | Using artificial intelligence to discover spatial, genomic, and pathologic biomarkers to guide and augment immune checkpoint inhibitor therapy for gastric cancer | 001 | 2 | NIH | 5/22/2025 | $66,562 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA276690 | Using artificial intelligence to discover spatial, genomic, and pathologic biomarkers to guide and augment immune checkpoint inhibitor therapy for gastric cancer | 000 | 2 | NIH | 3/3/2025 | $599,055 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AR078311 | Immunomodulation of juvenile femoral head osteonecrosis | 001 | 5 | NIH | 5/14/2025 | $39,815 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AR078311 | Immunomodulation of juvenile femoral head osteonecrosis | 000 | 5 | NIH | 3/10/2025 | $511,924 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK099110 | White Adipose Tissue Physiology, Mitochondrial Function and Adiponectin | 001 | 12 | NIH | 6/12/2025 | $62,426 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK099110 | White Adipose Tissue Physiology, Mitochondrial Function and Adiponectin | 000 | 12 | NIH | 2/14/2025 | $561,840 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS137584 | Chromatin regulation of neuronal activity-induced enhancer priming and epigenetic memory | 000 | 1 | NIH | 2/28/2025 | $578,632 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K24HL146838 | Mentoring Patient-Oriented Research in Deep Lipid Phenotyping for Cardiovascular Disease | 002 | 7 | NIH | 5/7/2025 | $122,720 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AI190103 | Machine learning for identifying antigen-antibody interactions from massive sequencing data | 000 | 1 | NIH | 2/28/2025 | $667,013 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS121038 | Defining the impact of Frataxin point mutations on Friedreich's ataxia pathogenesis | 000 | 5 | NIH | 2/14/2025 | $369,000 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K08CA286756 | Uncovering therapeutic vulnerabilities in AML through mechanistic interrogation of MECOM activity | 003 | 3 | NIH | 5/21/2025 | $228,979 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R03MH134200 | Regulation of Topoisomerase 2 Beta by phosphorylation at the C-Terminal domain | 000 | 2 | NIH | 2/14/2025 | $69,700 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA258987 | Artificial Intelligence-Based Quality Assurance for Online Adaptive Radiotherapy | 001 | 4 | NIH | 5/22/2025 | $58,883 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA258987 | Artificial Intelligence-Based Quality Assurance for Online Adaptive Radiotherapy | 000 | 4 | NIH | 2/14/2025 | $529,956 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K02NS140483 | Role of HP1β-mediated heterochromatin organization in neurodevelopmental disorders: CBX1-related syndrome as a model | 000 | 1 | NIH | 1/31/2025 | $264,600 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K08CA290062 | Defining mechanisms of immunotherapy resistance and targeting TIGIT in hepatobiliary cancers | 000 | 1 | NIH | 1/29/2025 | $270,981 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS107357 | Using deep brain stimulation of the parietal cortex to investigate the electrophysiology of human episodic memory | 003 | 8 | NIH | 6/27/2025 | $408,208 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK125713 | The role of ascorbate in myelopoiesis and infection | 000 | 5 | NIH | 3/4/2025 | $324,720 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS139492 | Dissection of NTSR2/calcium channel signaling as a non-opioid spinal analgesic mechanism for the treatment of high impact chronic pain | 000 | 1 | NIH | 2/1/2025 | $664,772 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01GM083122 | Structure and Function of Complexes that Regulate Ciliary Motility | 002 | 15 | NIH | 2/24/2025 | $460,506 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AR085116 | Molecular Mechanisms of Myoblast Fusion | 000 | 1 | NIH | 2/27/2025 | $439,791 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01EY034531 | The role of novel lincRNAs in regulating RGC survival after injury | 000 | 2 | NIH | 2/18/2025 | $410,000 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AR083904 | Metabolic regulation of osteoclast differentiation and bone resorption | 000 | 1 | NIH | 1/30/2025 | $588,302 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01HL176998 | Interpreting coding/non-coding variants for congenital heart disease through gene regulatory networks | 000 | 1 | NIH | 1/27/2025 | $802,762 |
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