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 | Issue Date FY: 2025 ( Subtotal = $59,993,402 ) (Continued on the next page) |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01MH132797 | The function of GABA/glutamate co-release in the habenula | 000 | 2 | NIH | 12/6/2024 | $480,993 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AR080676 | The role of nuclear envelope protein NET39 in skeletal muscle function and diseases | 000 | 3 | NIH | 1/16/2025 | $422,136 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R35GM156385 | Structural and Biochemical Mechanisms of Microtubule Dynamics and Regulation | 000 | 1 | NIH | 12/24/2024 | $651,001 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA288743 | Small Compound Inhibitors Targeting HPV Genome Replication | 000 | 1 | NIH | 11/29/2024 | $660,205 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK133229 | TVP23B and Golgi Mediated Control of Intestinal Secretory Cells | 000 | 2 | NIH | 12/23/2024 | $567,626 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AI114362 | Transcriptional regulatory mechanisms shaping HIV proviral fate | 000 | 11 | NIH | 12/6/2024 | $501,102 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AI169451 | Cell intrinsic antiviral mechanisms targeting human enteroviruses | 000 | 3 | NIH | 2/13/2025 | $454,541 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | F31NS132443 | The role of SMAD3 in gene networks underlying human brain activity | 000 | 2 | NIH | 1/1/2025 | $40,485 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | F30HL167629 | Unexpected mechanism underlying mislocalization of thrombocytopenia-associated ETV6 point mutation | 000 | 3 | NIH | 12/20/2024 | $46,839 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01EB035538 | Omni Oblique Plane Microscope to spread light-sheet based imaging in biomedical research | 000 | 2 | NIH | 1/13/2025 | $316,755 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA299152 | The kinase inhibited RTK forms a scaffold to drive therapeutic resistance in cancer | 000 | 1 | NIH | 3/27/2025 | $449,196 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA256833 | BBOX1 is a Novel Oncogenic Driver in Triple Negative Breast Cancer | 000 | 5 | NIH | 3/26/2025 | $355,583 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R21AI185226 | The Role of Sting in Lysosomal Storage Disorder | 000 | 2 | NIH | 3/26/2025 | $197,468 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA290297 | Molecular mechanisms and therapeutic principles of VISTA+ triple-negative breast cancers | 000 | 2 | NIH | 3/6/2025 | $414,810 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K08HL165047 | Endothelial Metabolic Reprogramming by Interferon-gamma in Coronary Artery Disease | 004 | 4 | NIH | 2/19/2025 | $169,020 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K99CA283246 | Data-driven mechanistic models of morphology-controlled Ras oncogenic signaling | 000 | 1 | NIH | 2/20/2025 | $140,097 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AR085116 | Molecular Mechanisms of Myoblast Fusion | 000 | 1 | NIH | 2/27/2025 | $439,791 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AG078417 | Gene Therapy Delivery for Age-related Neurodegenerative Diseases | 000 | 3 | NIH | 3/5/2025 | $643,570 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK128168 | Regulation of lipogenesis by TCA cycle metabolism | 000 | 5 | NIH | 2/20/2025 | $373,961 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK128166 | LIFR-alpha/JAK/STAT3-dependent Adipose Inflammation Contributes to Obesity-Associated NAFLD - Resubmissi | 000 | 4 | NIH | 2/20/2025 | $465,360 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS137042 | Positron Emission Tomography (PET)-Derived Measurement of Brain Synaptic Vesicle Glycoprotein 2A (SV2A) – a Potential Biomarker in Patients with Essential Tremor | 000 | 1 | NIH | 3/14/2025 | $679,899 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK135556 | Mechanistic Connection between Interorganellar Communication and Obesity-associated Diseases | 000 | 3 | NIH | 2/27/2025 | $380,586 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AI155786 | Regulation of Zbtb44-Eomes complex in CD8+T cells and anti-tumor immunity | 000 | 5 | NIH | 3/14/2025 | $397,780 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01MH085923 | Molecular mechanisms of axon guidance and neural connectivity | 000 | 13 | NIH | 3/18/2025 | $515,708 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AG079094 | Role of KDM6B in Alzheimer’s disease related dementia | 000 | 3 | NIH | 3/18/2025 | $674,557 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AI158351 | Circadian control of enteric virus infection | 000 | 5 | NIH | 3/21/2025 | $583,262 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | UG1DA020024 | NIDA Clinical Trials Network: Big South/West Node | 003 | 21 | NIH | 3/20/2025 | $0 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R21MH139200 | Phosphorylation-mediated regulation of Arc interactions with the AMPA receptor endocytic machinery | 000 | 1 | NIH | 3/19/2025 | $328,000 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K08DC019416 | Role of Fragile X Mental Retardation Protein on Gene Expression in Auditory Brainstem Development | 000 | 6 | NIH | 3/19/2025 | $182,253 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | F30HL178281 | Understanding Transplant Relapse of the Myelodysplastic Syndromes through Early Detection of Residual Disease among Hematopoietic Stem Cells | 001 | 1 | NIH | 3/20/2025 | $0 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | UG1DA020024 | NIDA Clinical Trials Network: Big South/West Node | 002 | 21 | NIH | 2/28/2025 | $0 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA260705 | Virtual Biopsy with Tissue-level Accuracy in Glioma | 000 | 5 | NIH | 3/7/2025 | $567,878 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R03MH134200 | Regulation of Topoisomerase 2 Beta by phosphorylation at the C-Terminal domain | 000 | 2 | NIH | 2/14/2025 | $69,700 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R00AR081897 | Comprehensive investigation of SP7 during the osteoblast-to-osteocyte transition | 001 | 4 | NIH | 3/25/2025 | $220,847 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01MH129185 | Hybrid implementation-effectiveness study to optimize HIV testing and PrEP in a southern jail (HOTSPOT) | 000 | 4 | NIH | 2/14/2025 | $562,838 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K08HL157697 | Protein acetylation-dependent fatty acid metabolic dysfunction in HFpEF | 000 | 4 | NIH | 2/14/2025 | $147,673 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA258987 | Artificial Intelligence-Based Quality Assurance for Online Adaptive Radiotherapy | 000 | 4 | NIH | 2/14/2025 | $529,956 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01NS110853 | Cell Type Specific Genetic Manipulation to Dissect Cholinergic Interneuron Function and Plasticity in a Symptomatic Model of DYT1 Dystonia | 000 | 5 | NIH | 2/14/2025 | $454,382 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01AG079513 | Characterization of how mRNA translation influences reproductive aging | 000 | 4 | NIH | 3/7/2025 | $302,580 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA273595 | Novel regulatory mechanisms and agonists of STING | 000 | 3 | NIH | 2/14/2025 | $612,538 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01DK099110 | White Adipose Tissue Physiology, Mitochondrial Function and Adiponectin | 000 | 12 | NIH | 2/14/2025 | $561,840 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01GM145744 | Uncovering novel players in nucleolar organization and function | 000 | 4 | NIH | 3/25/2025 | $295,200 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA269787 | Multiplexed nanoparticle delivery to increase CRISPR/Cas gene editing for enhanced cancer therapy | 000 | 4 | NIH | 2/28/2025 | $352,549 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01HG013358 | Spatially Resolved Molecular Measurement of Biomolecular Condensates | 000 | 2 | NIH | 2/14/2025 | $405,331 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA289435 | Mechanisms of Chromosome Shattering from Defective DNA Replication | 000 | 2 | NIH | 3/3/2025 | $397,312 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R01CA280135 | High-Precision Proton Therapy for Liver Cancer: Developing an End-to-end Strategy with Real-time Liver Tumor Localization and On-the-fly Plan Delivery Adaptation | 000 | 2 | NIH | 3/3/2025 | $545,737 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | UG1CA233302 | UT Southwestern NCI National Clinical Trials Network (NCTN) LAPS - Funded Extension Supplement YR6 | 000 | 6 | NIH | 3/3/2025 | $440,784 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | R21AI183574 | Discovery of pertussis toxin receptors | 000 | 2 | NIH | 3/11/2025 | $198,850 |
| | 2025 | 2025 | THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER | 5323 HARRY HINES BLVD | DALLAS | TX | 75390-7208 | DALLAS | USA | K23DK141959 | Survivorship Trajectories After Liver Transplantation: Identifying At‐Risk Survivors Needing Intervention | 000 | 1 | NIH | 3/3/2025 | $182,689 |
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