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 | Issue Date FY: 2025 ( Subtotal = $7,184,362 ) |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG061558 | Improving cancer-related fatigue, sexual dysfunction and quality of life in older men with cancer and androgen deficiency | 002 | 5 | NIH | 6/13/2025 | $54,036 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG084552 | Investigating how SUT-6/NIPP1 regulates pathological tau | 000 | 2 | NIH | 3/31/2025 | $462,220 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R00AG073455 | Mutant Tubulins Confer Resistance to Pathological Tau | 000 | 5 | NIH | 7/11/2025 | $244,021 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01DK134502 | Effects of Cholesterol in Pancreatic Islets | 000 | 3 | NIH | 4/10/2025 | $387,718 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01NS129573 | Role of Sleep Disruption after mTBI as a Driver of Chronic Post-traumatic Headache | 000 | 3 | NIH | 6/13/2025 | $600,438 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01DK132355 | Circulating miRNAs and prediction of beta-cell treatment response: The Restoring Insulin Secretion Study | 000 | 4 | NIH | 2/26/2025 | $461,835 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01DA052618 | Microglia and Opioid Withdrawal: Mechanisms of Negative Reinforcement | 000 | 5 | NIH | 6/17/2025 | $397,287 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG066729 | TDP-43 in Alzheimer's disease | 000 | 5 | NIH | 4/28/2025 | $460,291 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG066729 | TDP-43 in Alzheimer's disease | 001 | 5 | NIH | 6/13/2025 | $40,915 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01CA243907 | Improving the Reach and Effectiveness of Smoking Cessation Services Targeted to Veterans Living with HIV | 001 | 6 | NIH | 5/21/2025 | $0 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01CA243907 | Improving the Reach and Effectiveness of Smoking Cessation Services Targeted to Veterans Living with HIV | 000 | 6 | NIH | 2/28/2025 | $305,838 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01CA239208 | Improving Patient-Important Outcomes with Testosterone Replacement in Hypogonadal Men with a Prior History of Cancer | 001 | 6 | NIH | 5/22/2025 | $51,711 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01CA239208 | Improving Patient-Important Outcomes with Testosterone Replacement in Hypogonadal Men with a Prior History of Cancer | 000 | 6 | NIH | 4/30/2025 | $465,404 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG084680 | Formation of Tau RNA Complexes disrupts tau function and drives tau neuropathology | 000 | 3 | NIH | 7/10/2025 | $661,062 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01CA279220 | SArcopenia in Men with Prostate Cancer undergoing ADT (SAP-ADT) | 000 | 2 | NIH | 1/13/2025 | $583,926 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01CA279220 | SArcopenia in Men with Prostate Cancer undergoing ADT (SAP-ADT) | 001 | 2 | NIH | 7/16/2025 | $64,880 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG075338 | Role of Astrocyte EAAT2/GLT1 Failure in Alzheimer's Disease Pathogenesis | 000 | 4 | NIH | 1/15/2025 | $643,846 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01NS119897 | Investigating the role of lipid metabolism in protein aggregation and neurodegenerative disease progression | 000 | 5 | NIH | 11/26/2024 | $318,592 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01DK133317 | Role of the Renin-Angiotensin System in Glucose Homeostasis | 000 | 4 | NIH | 6/30/2025 | $392,118 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG061558 | Improving cancer-related fatigue, sexual dysfunction and quality of life in older men with cancer and androgen deficiency | 001 | 5 | NIH | 4/15/2025 | $0 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG084552 | Investigating how SUT-6/NIPP1 regulates pathological tau | 001 | 2 | NIH | 6/10/2025 | $41,086 |
| | 2025 | 2025 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG061558 | Improving cancer-related fatigue, sexual dysfunction and quality of life in older men with cancer and androgen deficiency | 000 | 5 | NIH | 3/27/2025 | $607,889 |
| | 2025 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R33AG064271 | Use of wearable sensors to improve the early diagnosis of DLB | 000 | 5 | NIH | 6/9/2025 | $0 |
| | 2025 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AR076475 | Characterizing and Restoring Joint Motion in Patients with Hallux Rigidus | 000 | 5 | NIH | 7/24/2025 | $0 |
| | 2025 | 2023 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R21NS118476 | Investigating a neuroprotective role of GBA in astrocytes | 000 | 2 | NIH | 6/26/2025 | -$980 |
| | 2025 | 2022 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R21MH123840 | User-centered Design and Evaluation of a Virtual Human Patient to Improve Safety Planning Skills | 000 | 2 | NIH | 3/25/2025 | -$3,744 |
| | 2025 | 2022 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01MH116883 | Genetic Dissection of Catecholaminergic Innervation of the Cognitive Cerebellum | 000 | 5 | NIH | 10/21/2024 | -$56,026 |
| | 2025 | 2022 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01NS064131 | Developing Neuroprotective Strategies for Tau and TDP-43 Proteinopathy in FTLD | 000 | 14 | NIH | 5/15/2025 | $0 |
| | 2025 | 2022 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01NS064131 | Developing Neuroprotective Strategies for Tau and TDP-43 Proteinopathy in FTLD | 000 | 14 | NIH | 5/15/2025 | $0 |
| | 2025 | 2022 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R21AA029601 | The Unfolding Role of Microglia in Alcohol Withdrawal | 000 | 2 | NIH | 1/3/2025 | $0 |
|
| Issue Date FY: 2024 ( Subtotal = $8,615,268 ) (Continued on the next page) |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R61AG080614 | Tai Chi Practice and Sleep-Active Glymphatic Function | 000 | 2 | NIH | 12/12/2023 | $423,374 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01DK134502 | Effects of Cholesterol in Pancreatic Islets | 001 | 2 | NIH | 5/8/2024 | $25,846 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01DK134502 | Effects of Cholesterol in Pancreatic Islets | 000 | 2 | NIH | 4/2/2024 | $387,718 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R00AG073455 | Mutant Tubulins Confer Resistance to Pathological Tau | 004 | 4 | NIH | 8/8/2024 | $52,759 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R00AG073455 | Mutant Tubulins Confer Resistance to Pathological Tau | 003 | 4 | NIH | 7/26/2024 | $0 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R00AG073455 | Mutant Tubulins Confer Resistance to Pathological Tau | 002 | 4 | NIH | 6/25/2024 | $249,000 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01NS129573 | Role of Sleep Disruption after mTBI as a Driver of Chronic Post-traumatic Headache | 000 | 2 | NIH | 6/27/2024 | $586,440 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG084552 | Investigating how SUT-6/NIPP1 regulates pathological tau | 000 | 1 | NIH | 7/26/2024 | $623,631 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG066211 | Protection from pathological tau by activation of the ER unfolded protein response | 001 | 5 | NIH | 6/10/2024 | $56,777 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG066211 | Protection from pathological tau by activation of the ER unfolded protein response | 000 | 5 | NIH | 1/8/2024 | $510,988 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01DK132355 | Circulating miRNAs and prediction of beta-cell treatment response: The Restoring Insulin Secretion Study | 001 | 3 | NIH | 5/15/2024 | $28,863 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01DK132355 | Circulating miRNAs and prediction of beta-cell treatment response: The Restoring Insulin Secretion Study | 000 | 3 | NIH | 2/12/2024 | $432,974 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01DA052618 | Microglia and Opioid Withdrawal: Mechanisms of Negative Reinforcement | 001 | 4 | NIH | 6/28/2024 | $383,712 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG066729 | TDP-43 in Alzheimer's disease | 000 | 4 | NIH | 5/17/2024 | $530,161 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AR076475 | Characterizing and Restoring Joint Motion in Patients with Hallux Rigidus | 000 | 5 | NIH | 8/7/2024 | $263,768 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01CA239208 | Improving Patient-Important Outcomes with Testosterone Replacement in Hypogonadal Men with a Prior History of Cancer | 000 | 5 | NIH | 7/24/2024 | $631,770 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01AG084680 | Formation of Tau RNA Complexes disrupts tau function and drives tau neuropathology | 001 | 2 | NIH | 6/21/2024 | $647,228 |
| | 2024 | 2024 | SEATTLE INSTITUTE FOR BIOMEDICAL AND CLINICAL RESEARCH | 1660 S COLUMBIAN WAY | SEATTLE | WA | 98108-1532 | KING | USA | R01CA279220 | SArcopenia in Men with Prostate Cancer undergoing ADT (SAP-ADT) | 000 | 1 | NIH | 1/12/2024 | $651,680 |
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