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 | Issue Date FY: 2026 ( Subtotal = $13,508,203 ) |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | K22AI191864 | Defining the single-cell epigenetic landscape of the HIV-1 reservoir for effective latency reversal | 001 | 1 | NIH | 2/13/2026 | $0 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R35GM162712 | Compartmentalization and discrimination of dsRNA in the nucleus | 000 | 1 | NIH | 2/26/2026 | $506,550 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R37CA280869 | Characterizing the sources, mechanisms, and translational relevance of microbial TMAO in driving anti-tumor immunity in pancreatic cancer. | 000 | 3 | NIH | 3/6/2026 | $566,752 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R35GM161559 | The role of non-canonical nucleic acid structures in genome regulation | 000 | 1 | NIH | 3/16/2026 | $363,191 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R35GM162440 | Investigating Mechanisms Controlling the Development of Tim4+ Macrophages | 000 | 1 | NIH | 3/25/2026 | $506,550 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS135217 | R-loop functions in neuronal gene expression and genome organization | 000 | 3 | NIH | 3/5/2026 | $515,658 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01LM014503 | Computational methods for discovery of disease-modulating microbial genes | 000 | 3 | NIH | 2/10/2026 | $408,771 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA301573 | Cell intrinsic and extrinsic effects of zinc metabolism in therapy resistant melanoma | 003 | 3 | NIH | 3/19/2026 | $736,226 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA298386 | Acylcarnitine Metabolism in Ovarian Cancer Chemoresistance | 001 | 2 | NIH | 2/19/2026 | $671,518 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DE017336 | Epigenetic Regulation of Epstein-Barr Virus | 000 | 18 | NIH | 12/10/2025 | $328,140 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA279585 | The genetics of tumor suppression by p53 | 000 | 4 | NIH | 3/9/2026 | $401,611 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA266342 | Therapeutic targeting MDSC-mediated immune suppression in cancer | 000 | 5 | NIH | 12/11/2025 | $626,865 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI172627 | Investigation into the activation of multiple bnAb precursors using structure-designed immunogens and Ig knock-in mice | 000 | 4 | NIH | 12/3/2025 | $909,225 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | U19AI166916 | Synthetic DNA-launched and adjuvanted Env immunogens for HIV | 000 | 4 | NIH | 1/9/2026 | $6,319,573 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | K22AI191864 | Defining the single-cell epigenetic landscape of the HIV-1 reservoir for effective latency reversal | 000 | 1 | NIH | 2/5/2026 | $162,000 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA102184 | Functional Analysis of p53 Polymorphic Variants | 000 | 19 | NIH | 10/28/2025 | $0 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI153508 | Regulation of EBV Latency by Purine Metabolism and Signaling | 000 | 5 | NIH | 3/5/2026 | $0 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI164570 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 2/25/2026 | $0 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI164570 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 2/25/2026 | $0 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI164570 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 2/25/2026 | $0 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI164570 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 2/25/2026 | $0 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI164570 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 2/25/2026 | $0 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI164570 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 2/25/2026 | $0 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DK124385 | Role of the p53 P47S mutation in influencing prevalence and immune response to H. pylori | 000 | 5 | NIH | 10/9/2025 | $0 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA301573 | Cell intrinsic and extrinsic effects of zinc metabolism in therapy resistant melanoma | 001 | 2 | NIH | 1/8/2026 | $273,065 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA259111 | Metabolic and epigenetic reprogramming in cyclin E high ovarian cancer | 003 | 6 | NIH | 2/17/2026 | $0 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA259111 | Metabolic and epigenetic reprogramming in cyclin E high ovarian cancer | 001 | 6 | NIH | 12/12/2025 | $212,508 |
| | 2026 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DK123733 | Glycomic Modulation of Gut Microbiome During HIV Infection | 001 | 5 | NIH | 3/12/2026 | $0 |
| | 2026 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DK123733 | Glycomic Modulation of Gut Microbiome During HIV Infection | 000 | 5 | NIH | 1/7/2026 | $0 |
| | 2026 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA268510 | Targeting S6K2 to Overcome Drug Resistance in NRAS-mutant Melanoma | 000 | 3 | NIH | 1/16/2026 | $0 |
| | 2026 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA238457 | A cancer-derived truncating mutation in disease penetrance and progression of MSI CRC | 000 | 6 | NIH | 3/26/2026 | $0 |
| | 2026 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R00AI159049 | dsRNA production and sensing during DNA virus infection | 000 | 4 | NIH | 2/4/2026 | $0 |
| | 2026 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DA048728 | Effects of mu-opiate receptor engagement on microbial translocation and residual immune activation in HIV-infected, ART suppressed opioid use disorder patents initiating medication-assisted treatment | 000 | 5 | NIH | 12/9/2025 | $0 |
| | 2026 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P01CA114046 | Targeted Therapies in Melanoma | 000 | 15 | NIH | 1/13/2026 | $0 |
| | 2026 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI141236 | Novel DNA encoded monoclonal antibodies (DMAbs) for control of Antimicrobial Resistant (AMR) Pseudomonas aeruginosa infection | 000 | 4 | NIH | 1/22/2026 | $0 |
| | 2026 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P01AI165066 | Structural vaccinology guided development of a universal CoV vaccine utilizing nucleic acid delivered nanoparticles | 000 | 1 | NIH | 1/20/2026 | $0 |
| | 2026 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | DP2AI175470 | Manipulating Epitope Immunodominance and Tracking B-cell-Antigen Interactions for Vaccine Design. | 000 | 1 | NIH | 1/15/2026 | $0 |
|
| Issue Date FY: 2025 ( Subtotal = $38,620,335 ) (Continued on the next page) |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R00CA282989 | Reprogramming T cell function with multiplexed genome engineering to develop next-generation immunotherapy | 000 | 3 | NIH | 7/17/2025 | $249,000 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R37CA280869 | Characterizing the sources, mechanisms, and translational relevance of microbial TMAO in driving anti-tumor immunity in pancreatic cancer. | 000 | 2 | NIH | 2/17/2025 | $510,077 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA279585 | The genetics of tumor suppression by p53 | 001 | 3 | NIH | 5/27/2025 | $40,160 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA279585 | The genetics of tumor suppression by p53 | 000 | 3 | NIH | 3/17/2025 | $361,451 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS131912 | Metabolic and molecular regulation of myeloid cell functions in brain cancer | 002 | 3 | NIH | 8/5/2025 | $47,374 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS131912 | Metabolic and molecular regulation of myeloid cell functions in brain cancer | 001 | 3 | NIH | 3/27/2025 | $426,379 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA102184 | Functional Analysis of p53 Polymorphic Variants | 001 | 19 | NIH | 12/6/2024 | $86,392 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA102184 | Functional Analysis of p53 Polymorphic Variants | 000 | 19 | NIH | 11/21/2024 | $352,104 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R37CA240625 | Investigating p16 Loss in Pro-tumorigenic Metabolism | 001 | 6 | NIH | 9/10/2025 | $874,892 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS135217 | R-loop functions in neuronal gene expression and genome organization | 000 | 2 | NIH | 3/26/2025 | $464,093 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R00CA267677 | Integrated analyses of the epigenome to understand the molecular basis of hematopoietic malignancies | 000 | 5 | NIH | 8/5/2025 | $249,000 |
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