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 | Issue Date FY: 2026 ( Subtotal = $38,239,084 ) (Continued on the next page) |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R21AI200716 | Cross-sectional study to identify host plasma biomarkers and Somalogic disease prognosis scores associated with cellular HIV-1 RNA expression in ART suppressed persons | 000 | 1 | NIH | 6/1/2026 | $506,550 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R21AI200714 | Neutralizing persistent IFN-I to improve HIV-specific CAR T cell therapy | 000 | 1 | NIH | 6/12/2026 | $506,550 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI203565 | Investigating N332-glycan independent V3-glycan antibodies as novel targets for HIV-1 vaccine design | 000 | 1 | NIH | 6/30/2026 | $888,042 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R21CA297425 | Myeloid cell-derived interleukin 1b promotes chemoresistance in metastatic ovarian cancer | 000 | 1 | NIH | 4/3/2026 | $473,624 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R21AI199951 | Nanobodies against Lymphocyte Activation Gene 3 for Inflammation Regulation and Cancer Immunotherapy | 000 | 1 | NIH | 7/21/2026 | $281,620 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | K22AI191864 | Defining the single-cell epigenetic landscape of the HIV-1 reservoir for effective latency reversal | 001 | 1 | NIH | 2/13/2026 | $0 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | K22AI191864 | Defining the single-cell epigenetic landscape of the HIV-1 reservoir for effective latency reversal | 000 | 1 | NIH | 2/5/2026 | $162,000 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI197956 | Epitope-engineered HSCs to permit CAR-T cell-mediated CD4-depletion for HIV cure | 000 | 1 | NIH | 7/13/2026 | $707,928 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI200748 | Redirecting Antibody Epitope Specificity with HIV-1 Env-Based Immunization | 000 | 1 | NIH | 5/4/2026 | $887,239 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R35GM162712 | Compartmentalization and discrimination of dsRNA in the nucleus | 000 | 1 | NIH | 2/26/2026 | $506,550 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R35GM162440 | Investigating Mechanisms Controlling the Development of Tim4+ Macrophages | 000 | 1 | NIH | 3/25/2026 | $506,550 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R00CA282989 | Reprogramming T cell function with multiplexed genome engineering to develop next-generation immunotherapy | 000 | 4 | NIH | 5/20/2026 | $249,000 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI130209 | Regulation of Viral Chromatin Architecture During EBV Latency | 000 | 9 | NIH | 5/26/2026 | $548,396 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS131912 | Metabolic and molecular regulation of myeloid cell functions in brain cancer | 000 | 4 | NIH | 4/7/2026 | $471,604 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA279585 | The genetics of tumor suppression by p53 | 000 | 4 | NIH | 3/9/2026 | $401,611 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA262631 | New control of oncogene activation in T-cell leukemia | 000 | 5 | NIH | 4/2/2026 | $529,915 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R37CA280869 | Characterizing the sources, mechanisms, and translational relevance of microbial TMAO in driving anti-tumor immunity in pancreatic cancer. | 000 | 3 | NIH | 3/6/2026 | $566,752 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA102184 | Functional Analysis of p53 Polymorphic Variants | 002 | 20 | NIH | 6/1/2026 | $433,100 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI181671 | MEPCS (Multi-epitope protease cleavage sites) vaccine for protecting against SIV rectal transmission | 001 | 3 | NIH | 6/9/2026 | $616,494 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI191272 | Individualized HIV Curative Combination Strategy against Persistent HIV on ART | 000 | 2 | NIH | 7/6/2026 | $3,369,553 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI182056 | Remodeling of the host epigenome during EBV infection | 000 | 3 | NIH | 5/4/2026 | $570,228 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI186810 | Developing potent HIV-specific CAR T cells through optimizing antigen sensitivity | 000 | 3 | NIH | 5/19/2026 | $558,595 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS135217 | R-loop functions in neuronal gene expression and genome organization | 000 | 3 | NIH | 3/5/2026 | $515,658 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA286080 | Parkin tumor suppression | 001 | 3 | NIH | 7/20/2026 | $1,498,878 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01LM014503 | Computational methods for discovery of disease-modulating microbial genes | 000 | 3 | NIH | 2/10/2026 | $408,771 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P01CA269043 | Targeting the Epigenetic and Metabolic Control of EBV-Epithelial Cancers | 000 | 4 | NIH | 4/27/2026 | $2,411,466 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS127828 | CTCF-dependent mechanisms of ATRX in neuronal differentiation | 000 | 5 | NIH | 7/7/2026 | $530,646 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI172627 | Investigation into the activation of multiple bnAb precursors using structure-designed immunogens and Ig knock-in mice | 000 | 4 | NIH | 12/3/2025 | $909,225 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R35GM161559 | The role of non-canonical nucleic acid structures in genome regulation | 000 | 1 | NIH | 3/16/2026 | $363,191 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA301573 | Cell intrinsic and extrinsic effects of zinc metabolism in therapy resistant melanoma | 003 | 3 | NIH | 3/19/2026 | $736,226 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DE017336 | Epigenetic Regulation of Epstein-Barr Virus | 001 | 18 | NIH | 4/15/2026 | $36,460 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DE017336 | Epigenetic Regulation of Epstein-Barr Virus | 000 | 18 | NIH | 12/10/2025 | $328,140 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P30CA010815 | Consolidated Basic Cancer Research Program | 000 | 57 | NIH | 4/6/2026 | $2,855,437 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA117830 | Epigenomic Control of KSHV Latency | 000 | 19 | NIH | 6/8/2026 | $410,175 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | U19AI166916 | Synthetic DNA-launched and adjuvanted Env immunogens for HIV | 001 | 4 | NIH | 4/10/2026 | $0 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | U19AI166916 | Synthetic DNA-launched and adjuvanted Env immunogens for HIV | 000 | 4 | NIH | 1/9/2026 | $6,319,573 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA298386 | Acylcarnitine Metabolism in Ovarian Cancer Chemoresistance | 001 | 2 | NIH | 2/19/2026 | $671,518 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA266342 | Therapeutic targeting MDSC-mediated immune suppression in cancer | 001 | 5 | NIH | 4/17/2026 | $69,650 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA266342 | Therapeutic targeting MDSC-mediated immune suppression in cancer | 000 | 5 | NIH | 12/11/2025 | $626,865 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI186812 | Development of Broadly Neutralizing Nanobodies for Advancing AIDS Therapy | 001 | 3 | NIH | 7/7/2026 | $745,781 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI186812 | Development of Broadly Neutralizing Nanobodies for Advancing AIDS Therapy | 001 | 3 | NIH | 7/7/2026 | $101,697 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA289624 | Transcriptional Reprogramming in Melanoma Plasticity | 001 | 3 | NIH | 6/30/2026 | $1,783,158 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R35GM153277 | Regulation of gene expression by alternative polyadenylation | 000 | 3 | NIH | 4/2/2026 | $664,842 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01GM152664 | Control of transcriptional integrity by Integrator and PP2A | 000 | 1 | NIH | 5/25/2026 | $591,549 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA293027 | Investigating BCAA oxidation and signaling in macrophages to drive anti-tumor immunity in PDAC | 000 | 1 | NIH | 4/9/2026 | $780,764 |
| | 2026 | 2026 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA303116 | Elucidation of targetable mechanisms sustaining immunosuppressive neutrophils in the brain tumor microenvironment | 000 | 1 | NIH | 5/20/2026 | $651,940 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA259111 | Metabolic and epigenetic reprogramming in cyclin E high ovarian cancer | 003 | 6 | NIH | 2/17/2026 | $0 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA259111 | Metabolic and epigenetic reprogramming in cyclin E high ovarian cancer | 001 | 6 | NIH | 12/12/2025 | $212,508 |
| | 2026 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA140652 | Role of TERRA in Telomere Maintenance and Telomere Stress Response | 000 | 15 | NIH | 5/28/2026 | $0 |
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