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 | Issue Date FY: 2025 ( Subtotal = $29,280,181 ) (Continued on the next page) |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA259171 | Drugging EBNA1 to Treat EBV-Associated Cancers | 000 | 5 | NIH | 7/11/2025 | $581,554 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS131912 | Metabolic and molecular regulation of myeloid cell functions in brain cancer | 002 | 3 | NIH | 3/27/2025 | $426,379 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI130209 | Regulation of Viral Chromatin Architecture During EBV Latency | 001 | 8 | NIH | 5/22/2025 | $541,989 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R00CA282989 | Reprogramming T cell function with multiplexed genome engineering to develop next-generation immunotherapy | 000 | 3 | NIH | 7/17/2025 | $249,000 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA279585 | The genetics of tumor suppression by p53 - Diversity Supplement | 001 | 3 | NIH | 5/27/2025 | $40,160 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA279585 | The genetics of tumor suppression by p53 - Diversity Supplement | 000 | 3 | NIH | 3/17/2025 | $361,451 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA262631 | New control of oncogene activation in T-cell leukemia | 001 | 4 | NIH | 5/22/2025 | $52,542 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA262631 | New control of oncogene activation in T-cell leukemia | 000 | 4 | NIH | 3/7/2025 | $472,885 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R37CA280869 | Characterizing the sources, mechanisms, and translational relevance of microbial TMAO in driving anti-tumor immunity in pancreatic cancer. | 001 | 2 | NIH | 5/22/2025 | $56,675 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R37CA280869 | Characterizing the sources, mechanisms, and translational relevance of microbial TMAO in driving anti-tumor immunity in pancreatic cancer. | 000 | 2 | NIH | 2/17/2025 | $510,077 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA140652 | Role of TERRA in Telomere Maintenance and Telomere Stress Response | 001 | 15 | NIH | 5/29/2025 | $43,469 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA140652 | Role of TERRA in Telomere Maintenance and Telomere Stress Response | 000 | 15 | NIH | 1/13/2025 | $391,227 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA102184 | Functional Analysis of p53 Polymorphic Variants | 000 | 19 | NIH | 11/21/2024 | $352,104 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA102184 | Functional Analysis of p53 Polymorphic Variants | 002 | 19 | NIH | 6/2/2025 | $39,123 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA102184 | Functional Analysis of p53 Polymorphic Variants | 001 | 19 | NIH | 12/6/2024 | $86,392 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI191272 | Individualized HIV Curative Combination Strategy against Persistent HIV on ART | 000 | 1 | NIH | 7/3/2025 | $3,568,644 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI186810 | Developing potent HIV-specific CAR T cells through optimizing antigen sensitivity | 000 | 2 | NIH | 5/2/2025 | $558,595 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI182056 | Remodeling of the host epigenome during EBV infection | 000 | 2 | NIH | 4/28/2025 | $543,298 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS135217 | R-loop functions in neuronal gene expression and genome organization | 000 | 2 | NIH | 3/26/2025 | $464,093 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA286080 | Parkin tumor suppression | 000 | 2 | NIH | 6/27/2025 | $499,626 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01LM014503 | Computational methods for discovery of disease-modulating microbial genes | 001 | 2 | NIH | 6/26/2025 | $41,271 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01LM014503 | Computational methods for discovery of disease-modulating microbial genes | 000 | 2 | NIH | 3/18/2025 | $371,441 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01GM143229 | ADNP mechanisms in R-loop regulation during differentiation | 000 | 4 | NIH | 7/16/2025 | $425,640 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R00CA267677 | Integrated analyses of the epigenome to understand the molecular basis of hematopoietic malignancies | 000 | 5 | NIH | 8/5/2025 | $249,000 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P01CA269043 | Targeting the Epigenetic and Metabolic Control of EBV-Epithelial Cancers | 000 | 3 | NIH | 5/23/2025 | $2,420,381 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA282411 | EBNA1 Inhibitor for Treatment of EBV-positive DLBCL | 001 | 3 | NIH | 7/3/2025 | $534,316 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS127828 | CTCF-dependent mechanisms of ATRX in neuronal differentiation | 000 | 4 | NIH | 7/7/2025 | $530,646 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI153508 | Regulation of EBV Latency by Purine Metabolism and Signaling | 000 | 5 | NIH | 5/2/2025 | $457,575 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI164570 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 7/14/2025 | $124,062 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI164570 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 7/14/2025 | $4,765,914 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI164570 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 7/14/2025 | $165,417 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI164570 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 7/14/2025 | $198,500 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI164570 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 7/14/2025 | $165,417 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI164570 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 7/14/2025 | $206,771 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA140964 | Autophagy-mediated defense against inflammation and cancer | 000 | 16 | NIH | 6/18/2025 | $434,696 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P30CA010815 | Consolidated Basic Cancer Research Program | 004 | 56 | NIH | 8/11/2025 | $155,014 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P30CA010815 | Consolidated Basic Cancer Research Program | 003 | 56 | NIH | 2/28/2025 | $2,678,721 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DE017336 | Epigenetic Regulation of Epstein-Barr Virus | 001 | 17 | NIH | 5/6/2025 | $36,460 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DE017336 | Epigenetic Regulation of Epstein-Barr Virus | 000 | 17 | NIH | 3/4/2025 | $328,140 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA117830 | Epigenomic Control of KSHV Latency | 000 | 18 | NIH | 6/27/2025 | $410,175 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | T32CA009171 | Training Program in Basic Cancer Research | 000 | 49 | NIH | 7/15/2025 | $489,395 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | U19AI166916 | Synthetic DNA-launched and adjuvanted Env immunogens for HIV | 000 | 3 | NIH | 12/19/2024 | $2,424,072 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DK124385 | Role of the p53 P47S mutation in influencing prevalence and immune response to H. pylori | 001 | 5 | NIH | 7/30/2025 | $60,035 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DK124385 | Role of the p53 P47S mutation in influencing prevalence and immune response to H. pylori | 000 | 5 | NIH | 12/13/2024 | $540,314 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA266342 | Therapeutic targeting MDSC-mediated immune suppression in cancer | 001 | 4 | NIH | 5/30/2025 | $69,650 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA266342 | Therapeutic targeting MDSC-mediated immune suppression in cancer | 000 | 4 | NIH | 11/20/2024 | $626,865 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA289624 | Transcriptional Reprogramming in Melanoma Plasticity | 000 | 2 | NIH | 6/10/2025 | $594,386 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R35GM153277 | Regulation of gene expression by alternative polyadenylation | 001 | 2 | NIH | 4/11/2025 | $664,842 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA272645 | Design of the First Mdm2 Targeting PROTACs for treatment of p53 Mutant or Deficient Cancers | 000 | 4 | NIH | 7/22/2025 | $544,697 |
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