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 | Issue Date FY: 2024 ( Subtotal = $14,828,593 ) (Continued on the next page) |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P30CA010815 | Consolidated Basic Cancer Research Program | 001 | 55 | NIH | 3/11/2024 | $8,371 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01LM014503 | Computational methods for discovery of disease-modulating microbial genes | 000 | 1 | NIH | 4/19/2024 | $425,531 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA279117 | Interrogating Type I Interferon signaling in breast cancer brain metastasis | 000 | 1 | NIH | 12/1/2023 | $529,002 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R37CA280869 | Characterizing the sources, mechanisms, and translational relevance of microbial TMAO in driving anti-tumor immunity in pancreatic cancer. | 000 | 1 | NIH | 3/6/2024 | $587,277 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R35GM153277 | Regulation of gene expression by alternative polyadenylation | 000 | 1 | NIH | 3/26/2024 | $587,032 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA279585 | The genetics of tumor suppression by p53 | 001 | 2 | NIH | 4/16/2024 | $20,080 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA279585 | The genetics of tumor suppression by p53 | 000 | 2 | NIH | 3/8/2024 | $361,451 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI172627 | Investigation into the activation of multiple bnAb precursors using structure-designed immunogens and Ig knock-in mice | 000 | 2 | NIH | 10/24/2023 | $819,869 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | U19AI166916 | Synthetic DNA-launched and adjuvanted Env immunogens for HIV | 000 | 2 | NIH | 1/12/2024 | $3,978,619 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA262631 | New control of oncogene activation in T-cell leukemia | 001 | 3 | NIH | 4/22/2024 | $25,936 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA262631 | New control of oncogene activation in T-cell leukemia | 000 | 3 | NIH | 3/27/2024 | $466,878 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA266342 | Therapeutic targeting MDSC-mediated immune suppression in cancer | 001 | 3 | NIH | 4/17/2024 | $34,825 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA266342 | Therapeutic targeting MDSC-mediated immune suppression in cancer | 000 | 3 | NIH | 11/20/2023 | $626,865 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DK124385 | Role of African-centric TP53 variant in higher H. pylori prevalence in African Americans | 000 | 4 | NIH | 12/15/2023 | $540,314 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DK123733 | Glycomic Modulation of Gut Microbiome During HIV Infection | 000 | 5 | NIH | 11/22/2023 | $752,645 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA238457 | A cancer-derived truncating mutation in disease penetrance and progression of MSI CRC | 000 | 6 | NIH | 11/15/2023 | $519,657 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA238611 | The impact of coding region variants on mutant p53 biology | 001 | 5 | NIH | 4/16/2024 | $22,243 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA238611 | The impact of coding region variants on mutant p53 biology | 000 | 5 | NIH | 11/14/2023 | $400,376 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA241490 | Understanding PPARgamma signaling in melanoma brain metastasis | 001 | 5 | NIH | 4/16/2024 | $20,372 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA241490 | Understanding PPARgamma signaling in melanoma brain metastasis | 000 | 5 | NIH | 11/13/2023 | $366,709 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA238457 | A cancer-derived truncating mutation in disease penetrance and progression of MSI CRC | 001 | 6 | NIH | 4/18/2024 | $28,869 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA140652 | Role of TERRA in Telomere Maintenance and Telomere Stress Response | 001 | 14 | NIH | 4/18/2024 | $21,734 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA140652 | Role of TERRA in Telomere Maintenance and Telomere Stress Response | 000 | 14 | NIH | 12/22/2023 | $391,227 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DE017336 | Epigenetic Regulation of Epstein-Barr Virus | 000 | 16 | NIH | 2/13/2024 | $328,140 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA102184 | Functional Analysis of p53 Polymorphic Variants | 003 | 18 | NIH | 4/16/2024 | $4,758 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA102184 | Functional Analysis of p53 Polymorphic Variants | 002 | 18 | NIH | 4/16/2024 | $19,562 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA102184 | Functional Analysis of p53 Polymorphic Variants | 000 | 18 | NIH | 11/13/2023 | $352,104 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA102184 | Functional Analysis of p53 Polymorphic Variants | 001 | 18 | NIH | 12/5/2023 | $85,655 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS135217 | R-loop functions in neuronal gene expression and genome organization | 000 | 1 | NIH | 2/19/2024 | $506,972 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P30CA010815 | Consolidated Basic Cancer Research Program | 000 | 55 | NIH | 2/29/2024 | $2,541,991 |
| | 2024 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA282411 | EBNA1 Inhibitor for Treatment of EBV-positive DLBCL | 000 | 1 | NIH | 2/22/2024 | $0 |
| | 2024 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R00AI159049 | dsRNA production and sensing during DNA virus infection | 000 | 3 | NIH | 3/21/2024 | $167 |
| | 2024 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R00CA267677 | Integrated analyses of the epigenome to understand the molecular basis of hematopoietic malignancies | 000 | 3 | NIH | 4/8/2024 | $16,051 |
| | 2024 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P50CA261608 | SPORE in Skin Cancer | 000 | 3 | NIH | 4/8/2024 | $0 |
| | 2024 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI153508 | Regulation of EBV Latency by Purine Metabolism and Signaling | 000 | 3 | NIH | 1/18/2024 | $0 |
| | 2024 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01GM084089 | Regulation of alternative cleavage and polyadenylation | 000 | 17 | NIH | 3/21/2024 | $0 |
| | 2024 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | T32CA009171 | Training Program in Basic Cancer Research | 000 | 47 | NIH | 12/11/2023 | $0 |
| | 2024 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | S10OD030244 | Purchase of a SARRP 200 Platform for Irradiation | 000 | 1 | NIH | 3/13/2024 | $0 |
| | 2024 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R24OD033719 | Purchase of MVE Fusion Self-Sustaining Cryogenic Freezers | 000 | 1 | NIH | 2/14/2024 | $0 |
| | 2024 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R21MH123753 | Molecular and neurodevelopmental consequences of ADNP mutation | 000 | 2 | NIH | 1/20/2024 | $0 |
| | 2024 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA225913 | A First-in-Human Phase I Clinical Trial of Mitochondrial-Targeted Hsp90 Inhibitor, Gamitrinib | 000 | 2 | NIH | 3/1/2024 | $0 |
| | 2024 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R21CA259240 | The role of gut microbe-derived choline metabolites in driving the pro-inflammatory macrophage phenotype and restricting pancreatic cancer | 000 | 2 | NIH | 1/12/2024 | $0 |
| | 2024 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R21AI158777 | Development of Broad Coronavirus Immunity Targeting the Fusion Peptide | 000 | 2 | NIH | 3/12/2024 | $0 |
| | 2024 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI135723 | Multivalent DNA vaccine-mediated protection against Tuberculosis | 000 | 5 | NIH | 10/18/2023 | $0 |
| | 2024 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA216936 | Negative regulation of myeloid-derived suppressive cells in cancer | 000 | 5 | NIH | 4/10/2024 | -$43,351 |
| | 2024 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA051497 | Defining the Role of the Cancer Circadian Clock in Tumor Immunity and Tumorigenesis | 000 | 30 | NIH | 11/14/2023 | -$213,236 |
| | 2024 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA093606 | Regulation of EBV Latency by EBNA1 | 000 | 20 | NIH | 1/17/2024 | $0 |
| | 2024 | 2021 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | F32GM143832 | Epigenetic Pathways in ATRX-Mediated CTCF Regulation | 000 | 1 | NIH | 12/28/2023 | -$1 |
| | 2024 | 2021 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01GM129069 | Regulation and Functions of 3'UTRs in Cellular Stress | 000 | 5 | NIH | 1/11/2024 | $0 |
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