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 | Issue Date FY: 2025 ( Subtotal = $9,198,538 ) |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | U19AI166916 | Synthetic DNA-launched and adjuvanted Env immunogens for HIV | 000 | 3 | NIH | 12/19/2024 | $2,424,072 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P30CA010815 | Consolidated Basic Cancer Research Program | 003 | 56 | NIH | 2/28/2025 | $2,678,721 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS135217 | R-loop functions in neuronal gene expression and genome organization | 000 | 2 | NIH | 3/26/2025 | $464,093 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS131912 | Metabolic and molecular regulation of myeloid cell functions in brain cancer | 002 | 3 | NIH | 3/27/2025 | $426,379 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R37CA280869 | Characterizing the sources, mechanisms, and translational relevance of microbial TMAO in driving anti-tumor immunity in pancreatic cancer. | 000 | 2 | NIH | 2/17/2025 | $510,077 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01LM014503 | Computational methods for discovery of disease-modulating microbial genes | 000 | 2 | NIH | 3/18/2025 | $371,441 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA279585 | The genetics of tumor suppression by p53 | 000 | 3 | NIH | 3/17/2025 | $361,451 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DE017336 | Epigenetic Regulation of Epstein-Barr Virus | 000 | 17 | NIH | 3/4/2025 | $328,140 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA102184 | Functional Analysis of p53 Polymorphic Variants | 001 | 19 | NIH | 12/6/2024 | $86,392 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA140652 | Role of TERRA in Telomere Maintenance and Telomere Stress Response | 000 | 15 | NIH | 1/13/2025 | $391,227 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA102184 | Functional Analysis of p53 Polymorphic Variants | 000 | 19 | NIH | 11/21/2024 | $352,104 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA266342 | Therapeutic targeting MDSC-mediated immune suppression in cancer | 000 | 4 | NIH | 11/20/2024 | $626,865 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI172627 | Investigation into the activation of multiple bnAb precursors using structure-designed immunogens and Ig knock-in mice | 000 | 3 | NIH | 10/29/2024 | $881,947 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA262631 | New control of oncogene activation in T-cell leukemia | 000 | 4 | NIH | 3/7/2025 | $472,885 |
| | 2025 | 2025 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01DK124385 | Role of African-centric TP53 variant in higher H. pylori prevalence in African Americans | 000 | 5 | NIH | 12/13/2024 | $540,314 |
| | 2025 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P30CA010815 | Consolidated Basic Cancer Research Program | 002 | 55 | NIH | 2/21/2025 | $433,606 |
| | 2025 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS131912 | Metabolic and molecular regulation of myeloid cell functions in brain cancer | 001 | 2 | NIH | 2/20/2025 | $38,505 |
| | 2025 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI165079 | Targeting Siglec-9/Sialoglycan Interactions to Enhance NK Functions During HIV Infection | 000 | 4 | NIH | 12/4/2024 | -$408,072 |
| | 2025 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R35GM153277 | Regulation of gene expression by alternative polyadenylation | 000 | 1 | NIH | 11/21/2024 | $0 |
| | 2025 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R21AI172616 | Engineering HIV-resistant CAR T cells for a functional HIV cure | 000 | 2 | NIH | 2/14/2025 | $0 |
| | 2025 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P30CA010815 | Consolidated Basic Cancer Research Program | 001 | 54 | NIH | 2/21/2025 | -$36,546 |
| | 2025 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01GM084089 | Regulation of alternative cleavage and polyadenylation | 000 | 17 | NIH | 4/1/2025 | -$113,037 |
| | 2025 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01GM084089 | Regulation of alternative cleavage and polyadenylation | 001 | 17 | NIH | 4/1/2025 | -$22,650 |
| | 2025 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R35CA220446 | Tumor Plasticity | 000 | 7 | NIH | 3/18/2025 | -$1 |
| | 2025 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01HL147472 | Regulation of neonatal inflammation by myeloid-derived suppressor cells | 000 | 4 | NIH | 3/19/2025 | $0 |
| | 2025 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AG062383 | Sialic Acid Modulation of HIV-associated Chronic Inflammaging | 000 | 5 | NIH | 1/6/2025 | -$219,257 |
| | 2025 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R00CA252025 | Modeling cancer evolution for prediction with neural networks: methods and applications | 000 | 4 | NIH | 12/3/2024 | -$30,553 |
| | 2025 | 2023 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P30CA010815 | Consolidated Basic Cancer Research Program | 000 | 54 | NIH | 2/21/2025 | -$397,060 |
| | 2025 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA165065 | Lipids and Myeloid Cell Function in Cancer | 000 | 10 | NIH | 11/5/2024 | $0 |
| | 2025 | 2022 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI130209 | Regulation of Viral Chromatin Architecture During EBV Latency | 000 | 6 | NIH | 2/10/2025 | $0 |
| | 2025 | 2020 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI126620 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 10/31/2024 | -$231,069 |
| | 2025 | 2020 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI126620 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 10/31/2024 | -$115,529 |
| | 2025 | 2020 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | UM1AI126620 | BEAT-HIV: Delaney Collaboratory to Cure HIV-1 Infection by Combination Immunotherapy | 000 | 5 | NIH | 10/31/2024 | -$615,908 |
|
| Issue Date FY: 2024 ( Subtotal = $37,447,352 ) (Continued on the next page) |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI182056 | Remodeling of the host epigenome during EBV infection | 000 | 1 | NIH | 6/7/2024 | $497,968 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI186810 | Developing potent HIV-specific CAR T cells through optimizing antigen sensitivity | 001 | 1 | NIH | 9/3/2024 | $55,858 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI186810 | Developing potent HIV-specific CAR T cells through optimizing antigen sensitivity | 000 | 1 | NIH | 6/7/2024 | $502,737 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01LM014503 | Computational methods for discovery of disease-modulating microbial genes | 000 | 1 | NIH | 4/19/2024 | $425,531 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA286080 | Parkin tumor suppression | 000 | 1 | NIH | 8/5/2024 | $499,626 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R00AI159049 | dsRNA production and sensing during DNA virus infection | 001 | 4 | NIH | 7/31/2024 | $249,000 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS135217 | R-loop functions in neuronal gene expression and genome organization | 000 | 1 | NIH | 2/19/2024 | $506,972 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | P01CA269043 | Targeting the Epigenetic and Metabolic Control of EBV-Epithelial Cancers | 000 | 2 | NIH | 5/7/2024 | $2,286,821 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R00CA267677 | Integrated analyses of the epigenome to understand the molecular basis of hematopoietic malignancies | 002 | 4 | NIH | 8/19/2024 | $232,949 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01GM143229 | ADNP mechanisms in R-loop regulation during differentiation | 000 | 3 | NIH | 7/26/2024 | $425,640 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA282411 | EBNA1 Inhibitor for Treatment of EBV-positive DLBCL | 001 | 2 | NIH | 6/26/2024 | $505,631 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01AI153508 | Regulation of EBV Latency by Purine Metabolism and Signaling | 001 | 4 | NIH | 4/25/2024 | $457,575 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA268510 | Targeting S6K2 to Overcome Drug Resistance in NRAS-mutant Melanoma | 000 | 3 | NIH | 7/31/2024 | $464,112 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01NS127828 | CTCF-dependent mechanisms of ATRX in neuronal differentiation | 000 | 3 | NIH | 7/1/2024 | $514,726 |
| | 2024 | 2024 | THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY | 3601 SPRUCE ST | PHILADELPHIA | PA | 19104-4205 | PHILADELPHIA | USA | R01CA238457 | A cancer-derived truncating mutation in disease penetrance and progression of MSI CRC | 001 | 6 | NIH | 4/18/2024 | $28,869 |
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