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 | Issue Date FY: 2025 ( Subtotal = $3,475,345 ) |
| | 2025 | 2025 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH132019 | Small-molecule probes for augmenting D5 receptor signaling | 000 | 3 | NIH | 11/20/2024 | $707,455 |
| | 2025 | 2025 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01DA055823 | Regulation of Gene Expression in the Human Habenula in Comorbid Opioid Addiction and Depression | 000 | 4 | NIH | 4/16/2025 | $680,018 |
| | 2025 | 2025 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01AG085933 | Impact of neuromelanin and Tau accumulation during aging and disease on local gene expression in the human locus coeruleus using spatially-resolved transcriptomics with protein detection | 000 | 2 | NIH | 3/27/2025 | $762,984 |
| | 2025 | 2025 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH126393 | Laminar dissection of cortical human brain gene expression in neuropsychiatric disorders | 000 | 5 | NIH | 4/15/2025 | $677,158 |
| | 2025 | 2025 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH137057 | Validation of electrophysiological biomarkers associated with performance in a preclinical assay of sustained attention | 000 | 2 | NIH | 4/10/2025 | $647,730 |
| | 2025 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH131817 | 1/2 Large-scale, single-cell characterization of molecular and cellular networks of mood regulation circuitry in major depressive disorder | 000 | 1 | NIH | 12/24/2024 | $0 |
| | 2025 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH131817 | 1/2 Large-scale, single-cell characterization of molecular and cellular networks of mood regulation circuitry in major depressive disorder | 001 | 1 | NIH | 3/13/2025 | $112,814 |
| | 2025 | 2023 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | K99MD016964 | Comprehensive computational analysis of genetic and regulatory differences between individuals with African and European ancestries across four brain regions | 000 | 2 | NIH | 3/11/2025 | $0 |
| | 2025 | 2023 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH123183 | Integrative cellular deconvolution of human brain RNA sequencing data | 000 | 4 | NIH | 5/13/2025 | $0 |
| | 2025 | 2023 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R56MH131817 | 1/2 Large-scale, single-cell characterization of molecular and cellular networks of mood regulation circuitry in major depressive disorder | 000 | 1 | NIH | 3/13/2025 | -$112,814 |
|
| Issue Date FY: 2024 ( Subtotal = $9,542,370 ) |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | F32MH139150 | Identifying a functional role for transcriptionally distinct, BLA-activated LS ensembles in social behaviors | 000 | 1 | NIH | 9/10/2024 | $78,828 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01DA053581 | Registration of spatial gene expression in key nodes of reward-related circuitry in the human brain | 000 | 4 | NIH | 7/24/2024 | $681,004 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH132019 | Small-molecule probes for augmenting D5 receptor signaling | 001 | 2 | NIH | 8/19/2024 | $83,771 |
| | 2024 | 2024 | LIEBER INSTITUTE, INC. | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH132019 | Small-molecule probes for augmenting D5 receptor signaling | 000 | 2 | NIH | 11/29/2023 | $753,942 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01AG085933 | Impact of neuromelanin and Tau accumulation during aging and disease on local gene expression in the human locus coeruleus using spatially-resolved transcriptomics with protein detection | 000 | 1 | NIH | 5/1/2024 | $867,306 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01HD107140 | Maternal SARS-CoV-2 infection, placenta biology, and neurodevelopmental outcomes in the offspring | 000 | 3 | NIH | 8/29/2024 | $715,918 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01HD107140 | Maternal SARS-CoV-2 infection, placenta biology, and neurodevelopmental outcomes in the offspring | 000 | 3 | NIH | 8/29/2024 | $715,837 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | F32MH135665 | Investigating the effects of TCF4 mutations during oligodendrocyte development and maturation in a human-derived model of autism spectrum disorder | 000 | 1 | NIH | 6/12/2024 | $74,284 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH134828 | Understanding Schizophrenia Risk Mechanisms Via Multimodal Analysis of Patient-derived Neurons and 3D Cortical Organoids and Correlation with Clinical and Cognitive Phenotypes | 000 | 1 | NIH | 8/6/2024 | $908,174 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH105592 | Molecular and Cellular Correlates of Plasticity in Hippocampal-Prefrontal Circuitry | 001 | 10 | NIH | 8/16/2024 | $57,282 |
| | 2024 | 2024 | LIEBER INSTITUTE, INC. | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH105592 | Molecular and Cellular Correlates of Plasticity in Hippocampal-Prefrontal Circuitry | 000 | 10 | NIH | 1/11/2024 | $515,552 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R21DA060407 | Integrated single cell and spatial mapping of habenula circuitry to identify projection-specific molecular pathways associated with opioid exposure. | 000 | 1 | NIH | 8/29/2024 | $284,040 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R00MD016964 | Comprehensive computational analysis of genetic and regulatory differences between individuals with African and European ancestries across four brain regions | 000 | 3 | NIH | 8/23/2024 | $249,000 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01DA055823 | Regulation of Gene Expression in the Human Habenula in Comorbid Opioid Addiction and Depression | 000 | 3 | NIH | 6/5/2024 | $671,089 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH126393 | Laminar dissection of cortical human brain gene expression in neuropsychiatric disorders | 001 | 4 | NIH | 8/16/2024 | $82,114 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH126393 | Laminar dissection of cortical human brain gene expression in neuropsychiatric disorders | 000 | 4 | NIH | 4/4/2024 | $739,028 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | F31MH138091 | Investigating TCF4 and Synaptic Dysfunction in Pitt-Hopkins Syndrome | 001 | 1 | NIH | 6/25/2024 | $0 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | F31MH138091 | Investigating TCF4 and Synaptic Dysfunction in Pitt-Hopkins Syndrome | 000 | 1 | NIH | 6/25/2024 | $42,574 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH110487 | Cellular and Molecular Analysis of the Psychiatric Risk Gene Transcription Factor 4 (TCF4) | 000 | 9 | NIH | 5/22/2024 | $636,290 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH131817 | 1/2 Large-scale, single-cell characterization of molecular and cellular networks of mood regulation circuitry in major depressive disorder | 000 | 1 | NIH | 9/5/2024 | $702,401 |
| | 2024 | 2024 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH137057 | Validation of electrophysiological biomarkers associated with performance in a preclinical assay of sustained attention | 000 | 1 | NIH | 7/10/2024 | $753,016 |
| | 2024 | 2023 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R56MH131817 | 1/2 Large-scale, single-cell characterization of molecular and cellular networks of mood regulation circuitry in major depressive disorder | 000 | 1 | NIH | 8/20/2024 | $0 |
| | 2024 | 2023 | LIEBER INSTITUTE, INC. | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | K99MD016964 | Comprehensive computational analysis of genetic and regulatory differences between individuals with African and European ancestries across four brain regions | 000 | 2 | NIH | 11/29/2023 | $0 |
| | 2024 | 2023 | LIEBER INSTITUTE, INC. | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | F32MH135620 | Neural substrates of extinction deficits in pathological fear | 002 | 1 | NIH | 12/19/2023 | -$69,080 |
| | 2024 | 2022 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R21MH125108 | Placental Transcriptomics and Risk for Schizophrenia | 000 | 2 | NIH | 4/15/2024 | $0 |
| | 2024 | 2022 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH117291 | 2/3 Understanding PTSD through Postmortem Targeted Brain Multi-omics | 000 | 5 | NIH | 7/26/2024 | $0 |
| | 2024 | 2021 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | U01MH122849 | Spatial registration of gene expression in the human brain | 000 | 2 | NIH | 9/13/2024 | $0 |
| | 2024 | 2021 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | U01MH122849 | Spatial registration of gene expression in the human brain | 001 | 2 | NIH | 9/13/2024 | $0 |
| | 2024 | 2021 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH112751 | Functional methylomics approaches for schizophrenia in the frontal cortex and hippocampus | 000 | 5 | NIH | 12/22/2023 | $0 |
| | 2024 | 2021 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R56MH126233 | NEUROPHYSIOLOGICAL BIOMARKERS IN PRECLINICAL ASSAYS OF SUSTAINED ATTENTION | 000 | 1 | NIH | 1/19/2024 | $0 |
| | 2024 | 2019 | THE LIEBER INSTITUTE | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | U01MH106893 | 1/3-Schizophrenia Genetics and Brain Somatic Mosaicism | 000 | 5 | NIH | 2/23/2024 | $0 |
|
| Issue Date FY: 2023 ( Subtotal = $8,850,607 ) (Continued on the next page) |
| | 2023 | 2023 | LIEBER INSTITUTE, INC. | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01MH123183 | Integrative cellular deconvolution of human brain RNA sequencing data | 000 | 4 | NIH | 2/24/2023 | $618,221 |
| | 2023 | 2023 | LIEBER INSTITUTE, INC. | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | K99MD016964 | Comprehensive computational analysis of genetic and regulatory differences between individuals with African and European ancestries across four brain regions | 002 | 2 | NIH | 1/11/2023 | $87,422 |
| | 2023 | 2023 | LIEBER INSTITUTE, INC. | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | K99MD016964 | Comprehensive computational analysis of genetic and regulatory differences between individuals with African and European ancestries across four brain regions | 002 | 2 | NIH | 1/11/2023 | -$87,422 |
| | 2023 | 2023 | LIEBER INSTITUTE, INC. | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R01DA053581 | Registration of spatial gene expression in key nodes of reward-related circuitry in the human brain | 000 | 3 | NIH | 7/21/2023 | $704,352 |
| | 2023 | 2023 | LIEBER INSTITUTE, INC. | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | R00GM137072 | Dissecting modular interaction of RNA with protein in chromatin | 000 | 4 | NIH | 9/13/2023 | $248,930 |
| | 2023 | 2023 | LIEBER INSTITUTE, INC. | 855 N WOLFE ST STE 300 | BALTIMORE | MD | 21205-1514 | BALTIMORE CITY | USA | K99MD016964 | Comprehensive computational analysis of genetic and regulatory differences between individuals with African and European ancestries across four brain regions | 000 | 2 | NIH | 11/8/2022 | $87,422 |
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