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 | Issue Date FY: 2025 ( Subtotal = $2,924,069 ) |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R21AG091047 | Mechanistic tRNA modification affects to aging | 000 | 1 | NIH | 11/14/2024 | $430,603 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R00HL153896 | YAP1, neointima formation, and blood pressure regulation | 000 | 5 | NIH | 11/27/2024 | $249,000 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01CA272760 | Enhancing chemotherapeutic efficacy in triple-negative breast cancer via DSTYK silence | 002 | 3 | NIH | 4/24/2025 | $118,756 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01CA272760 | Enhancing chemotherapeutic efficacy in triple-negative breast cancer via DSTYK silence | 001 | 3 | NIH | 3/25/2025 | $217,702 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01NS122534 | Pre and post-synaptic pathways underlying the stress response in the adrenal medulla | 000 | 10 | NIH | 4/10/2025 | $370,154 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01ES036248 | Developmental pyrethroid exposure in the prairie vole as a model of environmental risk for autism | 000 | 1 | NIH | 5/1/2025 | $605,550 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R00DA055064 | Investigating the long-term effects of prenatal circadian rhythm disruption on substance use-related disorders | 000 | 3 | NIH | 3/4/2025 | $248,996 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R03CA286634 | TAZ-driven Regulation of Tumor Microenvironment in Triple-Negative Breast Cancer | 002 | 3 | NIH | 12/23/2024 | $78,125 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01CA286189 | Dormancy mimicking to inhibit prostate cancer metastasis progression and recurrence | 001 | 1 | NIH | 4/10/2025 | -$636,185 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01CA286189 | Dormancy mimicking to inhibit prostate cancer metastasis progression and recurrence | 000 | 1 | NIH | 1/24/2025 | $636,185 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01DK134053 | Role of neutrophil extracellular traps (NETs) in Inflammatory bowel disease | 000 | 3 | NIH | 2/20/2025 | $387,115 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R03ES036303 | SWI/SNF in ultraviolet radiation-induced chromatin alterations | 000 | 1 | NIH | 12/19/2024 | $156,250 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01CA288278 | Molecular basis and targeting of FASN in expanding PARPi utility for TNBC | 000 | 1 | NIH | 12/19/2024 | $524,419 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 Arlington Ave | Toledo | OH | 43614-2598 | LUCAS | USA | H7600732 | Ryan White Part C Outpatient EIS Program | 00 | 24 | HRSA | 3/6/2025 | $129,999 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01HD104418 | Astrocyte insulin resistance-induced neuroendocrine defects in pubertal delay and hypogonadotropic hypogonadism | 000 | 4 | NIH | 1/21/2025 | $482,604 |
| | 2025 | 2025 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01HD104418 | Astrocyte insulin resistance-induced neuroendocrine defects in pubertal delay and hypogonadotropic hypogonadism | 001 | 4 | NIH | 4/24/2025 | $53,623 |
| | 2025 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01HL152162 | Neural mechanisms of host-microbiota interaction in hypertension: a potential for bio-electronic medicine | 000 | 4 | NIH | 4/24/2025 | $0 |
| | 2025 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01HL152162 | Neural mechanisms of host-microbiota interaction in hypertension: a potential for bio-electronic medicine | 002 | 4 | NIH | 5/7/2025 | -$393,908 |
| | 2025 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R03CA286634 | TAZ-driven Regulation of Tumor Microenvironment in Triple-Negative Breast Cancer | 001 | 2 | NIH | 12/20/2024 | $14,777 |
| | 2025 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01CA230744 | Influence of bone microenvironment on drug resistance in prostate cancer bone metastasis | 000 | 6 | NIH | 1/9/2025 | $0 |
| | 2025 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | U7723072 | Area Health Education Centers Point of Service Maintenance and Enhancement | 02 | 14 | HRSA | 5/7/2025 | $0 |
| | 2025 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | U7723072 | Area Health Education Centers Point of Service Maintenance and Enhancement | 01 | 14 | HRSA | 3/31/2025 | $0 |
| | 2025 | 2023 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R21MH125277 | A large sample machine learning network analysis of vertex cortical thickness measures for high resolution definition of PTSD related cortical structure abnormalities | 000 | 2 | NIH | 1/13/2025 | $0 |
| | 2025 | 2023 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R35GM150588 | Control of Klebsiella capsule biosynthesis and attachment | 000 | 1 | NIH | 2/28/2025 | -$180,607 |
| | 2025 | 2023 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R21MH127500 | The effect of SHANK3 mutation in transgenic prairie voles on natural social behaviors and genetic mechanisms | 000 | 2 | NIH | 4/8/2025 | -$6,970 |
| | 2025 | 2023 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01DE027343 | The role of platelets in protection against oral candidiasis | 000 | 5 | NIH | 5/5/2025 | -$64 |
| | 2025 | 2023 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | K01AA029763 | Targeting PI3K/BRD4 and Hedgehog Pathway in Alcohol Associated Liver Disease | 002 | 4 | NIH | 2/19/2025 | $7,506 |
| | 2025 | 2022 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01AI155545 | Anti-inflammatory functions for non-transcriptional IRF3 | 001 | 2 | NIH | 2/12/2025 | -$428,039 |
| | 2025 | 2022 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01CA219342 | ATR Isomerization in Cellular Responses to UV Damage of DNA | 000 | 6 | NIH | 1/2/2025 | -$46,868 |
| | 2025 | 2022 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01CA211904 | Molecular targeting the translational control axis in Wnt/beta-catenin signaling pathway | 000 | 6 | NIH | 3/14/2025 | -$191 |
| | 2025 | 2022 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01AI165521 | Novel antiviral mechanisms of the interferon system | 000 | 1 | NIH | 10/21/2024 | -$94,462 |
| | 2025 | 2021 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01DK114006 | The Melanocortinergic pathway inglomerular disease | 000 | 6 | NIH | 11/7/2024 | -$1 |
|
| Issue Date FY: 2024 ( Subtotal = $14,448,701 ) (Continued on the next page) |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | F30AG079633 | AMPK localization, expression, and activity in Alzheimer's Disease | 000 | 3 | NIH | 8/9/2024 | $42,791 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | T32GM144873 | Training in Molecular and translational Cell Dynamics | 000 | 3 | NIH | 4/17/2024 | $653,082 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01AG071332 | PPARG regulates osteocyte bioenergetics and function during aging | 000 | 4 | NIH | 6/4/2024 | $682,204 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01CA258682 | Targeting eIF4A1 in drug-resistant breast cancer stem-like cells | 002 | 3 | NIH | 9/9/2024 | $0 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01CA258682 | Targeting eIF4A1 in drug-resistant breast cancer stem-like cells | 001 | 3 | NIH | 8/9/2024 | $249,381 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01CA258682 | Targeting eIF4A1 in drug-resistant breast cancer stem-like cells | 000 | 3 | NIH | 7/22/2024 | $388,292 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | U01DA054330 | Cross platform analysis of drug targets and toxicity of bath salts | 002 | 3 | NIH | 6/28/2024 | $389,265 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | U01DA054330 | Cross platform analysis of drug targets and toxicity of bath salts | 001 | 3 | NIH | 6/7/2024 | $556,470 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01DK133203 | Role of GSK3beta in diabetic kidney disease | 000 | 3 | NIH | 7/1/2024 | $326,304 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01DK124098 | Gut-brain axis in Parkinson's disease | 000 | 4 | NIH | 8/26/2024 | $1 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01NS122534 | Pre and post-synaptic pathways underlying the stress response in the adrenal medulla | 001 | 9 | NIH | 4/25/2024 | $25,911 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01NS122534 | Pre and post-synaptic pathways underlying the stress response in the adrenal medulla | 000 | 9 | NIH | 2/19/2024 | $333,140 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01AI153496 | Understanding the proviral role for TRAF6 interaction with the viral protease in flavivirus replication and pathogenesis | 000 | 5 | NIH | 4/18/2024 | $386,250 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01HL152162 | Neural mechanisms of host-microbiota interaction in hypertension: a potential for bio-electronic medicine | 000 | 4 | NIH | 5/31/2024 | $439,948 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01NS112642 | Cofilin Signaling in Hemorrhagic Stroke | 001 | 5 | NIH | 8/2/2024 | -$11,620 |
| | 2024 | 2024 | UNIVERSITY OF TOLEDO | 3000 ARLINGTON AVE | TOLEDO | OH | 43614-2598 | LUCAS | USA | R01NS112642 | Cofilin Signaling in Hemorrhagic Stroke | 001 | 5 | NIH | 8/2/2024 | $11,620 |
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