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 | Issue Date FY: 2025 ( Subtotal = $94,062,932 ) (Continued on the next page) |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01ES033785 | Assessing how Prenatal Phthalate Exposure Disrupts Placental Transcriptional Regulation and Contributes to Changes in Gestational Length | 000 | 3 | NIH | 10/29/2024 | $675,801 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R50CA275857 | Pediatric brain tumors: Improving survival through integration of clinical molecular diagnostics and biologically targeted therapies into clinical trials | 000 | 3 | NIH | 3/13/2025 | $175,338 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K08CA256167 | Characterization of short H2A Oncohistones in Cancer | 000 | 4 | NIH | 7/31/2025 | $211,694 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AI170777 | Impairment of anti-Plasmodium T cell memory by type I Interferon Signaling | 001 | 3 | NIH | 5/15/2025 | $767,280 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | U01AI165455 | Collective Responses to Malaria Vaccination | 000 | 4 | NIH | 1/16/2025 | $679,001 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD109089 | Bifidobacterium infantis supplementation in early life to improve immunity in infants exposed to HIV: a randomized, placebo-controlled, double-blind trial | 001 | 4 | NIH | 8/4/2025 | $65,880 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD109089 | Bifidobacterium infantis supplementation in early life to improve immunity in infants exposed to HIV: a randomized, placebo-controlled, double-blind trial | 000 | 4 | NIH | 7/17/2025 | $695,796 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DA056370 | Regulation of Opioid Sensitivity and Tolerance by Ubiquitin Ligase Signaling | 000 | 4 | NIH | 5/16/2025 | $605,352 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DK131134 | Kids CoLab - Supporting collaborative decision making with youth impacted by chronic kidney disease | 000 | 4 | NIH | 8/9/2025 | $609,395 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K08CA263474 | Pilot trial testing mobile health psychosocial intervention for Adolescentsand Young Adults with cancer | 000 | 4 | NIH | 7/31/2025 | $204,152 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01NS122902 | A Bioengineering Approach to Develop a Laminar 3D Cerebellar Neuronal Circuit for Modeling Human Cerebellum | 000 | 4 | NIH | 4/9/2025 | $688,366 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD107794 | Randomized controlled trial of an internet-based prevention intervention for young children at-risk for functional abdominal pain | 000 | 4 | NIH | 4/7/2025 | $640,526 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01NR020441 | Adapted Comprehensive School Physical Activity Program | 000 | 5 | NIH | 7/31/2025 | $674,752 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R37CA289981 | B7-H3 CAR T cells following initial radiation for children and young adults with diffuse intrinsic pontine glioma | 000 | 1 | NIH | 5/26/2025 | $456,414 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AG077731 | Brain Drain: In Vivo Optical Interrogation of Venular Function in Gray and White Matter | 001 | 2 | NIH | 6/10/2025 | $62,217 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AG077731 | Brain Drain: In Vivo Optical Interrogation of Venular Function in Gray and White Matter | 000 | 2 | NIH | 5/2/2025 | $699,961 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01CA293587 | Identifying Relapse Predictors and Therapeutic Vulnerabilities in Ph+ and Ph-like Acute Lymphoblastic Leukemia | 000 | 1 | NIH | 7/29/2025 | $3,480,276 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01EY033364 | Optimizing Models of Non-Coding Genetic Risk in Age-Related Macular Degeneration | 000 | 4 | NIH | 2/14/2025 | $492,250 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD103700 | Brain Injury Outpatient Education and Care Navigation | 000 | 5 | NIH | 4/21/2025 | $589,533 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R21HD118297 | Use of Oscillometry for the Evaluation of Pulmonary Function Following Pediatric Acute Respiratory Failure. | 000 | 1 | NIH | 4/24/2025 | $224,083 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI177257 | Perturbations of host cell signaling by a complex hepatotropic pathogen | 000 | 13 | NIH | 2/13/2025 | $663,183 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | T32GM156698 | Invent@SC Clinical Pharmacology of Biotherapeutics | 000 | 1 | NIH | 7/17/2025 | $166,192 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R37CA266777 | The IL-18-IFNγ axis predicts response to immunotherapy | 001 | 3 | NIH | 6/16/2025 | $79,712 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R37CA266777 | The IL-18-IFNγ axis predicts response to immunotherapy | 000 | 3 | NIH | 2/14/2025 | $717,404 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AI014102 | Mitochondrial DNA of Normal and Mutant Trypanosomes | 001 | 48 | NIH | 4/25/2025 | $1,158,683 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | F32NS143860 | Brainstem control of apneic reflexes relating to respiratory deaths in neurological disorders | 000 | 1 | NIH | 7/30/2025 | $74,632 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | F32NS143860 | Brainstem control of apneic reflexes relating to respiratory deaths in neurological disorders | 001 | 1 | NIH | 7/30/2025 | $0 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AI185053 | Elucidating and targeting Siglec-9 function on mast cells | 000 | 1 | NIH | 7/23/2025 | $612,917 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01MD015723 | The Family Bridge Program to Improve Communication and Navigation-Related Outcomes for Minority Children and Families: A Randomized Controlled Trial | 001 | 4 | NIH | 4/17/2025 | $779,022 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DE033703 | Leveraging Data for Infants with Cleft to Grow and Flourish: The BLOOM Study | 003 | 2 | NIH | 8/12/2025 | $0 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DE033703 | Leveraging Data for Infants with Cleft to Grow and Flourish: The BLOOM Study | 004 | 2 | NIH | 8/14/2025 | $0 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DE033703 | Leveraging Data for Infants with Cleft to Grow and Flourish: The BLOOM Study | 002 | 2 | NIH | 5/9/2025 | $85,895 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DE033703 | Leveraging Data for Infants with Cleft to Grow and Flourish: The BLOOM Study | 001 | 2 | NIH | 4/18/2025 | $773,066 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01NS117434 | Endotelin-1 role in development and regeneration | 003 | 6 | NIH | 6/19/2025 | $615,241 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD111410 | Development of a Multiplex Proteomics Assay for High-Throughput Newborn Screening of a New Set of Treatable Neonatal Diseases | 001 | 3 | NIH | 6/18/2025 | $48,572 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HD111410 | Development of a Multiplex Proteomics Assay for High-Throughput Newborn Screening of a New Set of Treatable Neonatal Diseases | 000 | 3 | NIH | 2/12/2025 | $437,165 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01MH108519 | Regulation of mTOR signaling in the developing cerebral cortex as a point of convergence for multiple autism risk factors | 002 | 11 | NIH | 3/5/2025 | $415,863 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | UH3OD035508 | Mediators and Modifiers of Prenatal Environmental Exposures and Child Neurodevelopment: DNA methylation, Prenatal Diet, and Cognitive Stimulation (MEND) | 000 | 3 | NIH | 8/8/2025 | $328,076 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R21NS142543 | Investigating Cerebellar Development in Ferrets: Implications for Modelling Human Cerebellar Development and Disease | 000 | 1 | NIH | 7/28/2025 | $516,175 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K01DA058543 | Dissociating respiratory depression and analgesia via a data-driven model of interacting respiratory and pain networks | 000 | 3 | NIH | 3/20/2025 | $101,477 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01NS143924 | Modeling mTOR network dynamics to achieve optimal drug rescue of congenital mTORopathies | 000 | 1 | NIH | 6/26/2025 | $754,066 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K23HD100566 | Clinical factors associated with long-term recovery following pediatric critical illness and injury | 002 | 5 | NIH | 4/10/2025 | $155,736 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD106628 | Supraphysiologic Shear Stresses Associated with Cardiopulmonary Bypass are Sufficient to Activate RIKP3 Signaling | 000 | 4 | NIH | 2/18/2025 | $693,654 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD106628 | Supraphysiologic Shear Stresses Associated with Cardiopulmonary Bypass are Sufficient to Activate RIKP3 Signaling | 001 | 4 | NIH | 4/16/2025 | $77,073 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | U01DA060443 | Deep Analysis of Transcriptome to Understand the Genetics of Substance Use Disorders in Rats | 000 | 1 | NIH | 6/27/2025 | $944,888 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD116748 | Understanding Longitudinal Relationships between Sleep and Menstrual Pain in Adolescents | 000 | 1 | NIH | 8/8/2025 | $762,550 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AG081840 | Pericyte control of capillary perfusion in the Alzheimer's disease brain | 001 | 3 | NIH | 8/11/2025 | $67,496 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AG081840 | Pericyte control of capillary perfusion in the Alzheimer's disease brain | 000 | 3 | NIH | 2/14/2025 | $759,334 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R37NS109478 | Mechanisms of Oligodendrocyte and Axonal Abnormalities After Perinatal Brain Injury | 003 | 8 | NIH | 8/6/2025 | $455,000 |
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