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| Issue Date FY: 2025 ( Subtotal = $2,569,302 ) |
| 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI155536 | Structural Analysis and Inhibitor Optimization of Cryptosporidium n-myristoyltransferase for Drug Discovery | 000 | 5 | NIH | 11/6/2024 | $800,512 |
| 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL163103 | Hexosamine biosynthesis pathway metabolism during cardiac hypertrophy | 000 | 3 | NIH | 11/13/2024 | $735,425 |
| 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI188789 | Species-transcending prevention of mosquito vector infection | 000 | 1 | NIH | 11/14/2024 | $832,071 |
| 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01ES033785 | Assessing how Prenatal Phthalate Exposure Disrupts Placental Transcriptional Regulation and Contributes to Changes in Gestational Length | 001 | 3 | NIH | 10/30/2024 | $101,793 |
| 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01ES033785 | Assessing how Prenatal Phthalate Exposure Disrupts Placental Transcriptional Regulation and Contributes to Changes in Gestational Length | 000 | 3 | NIH | 10/29/2024 | $675,801 |
| 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K01MD019730 | Youth climate activism on social media: Building psychosocial resilienceamong minority youth | 001 | 2 | NIH | 11/1/2024 | $127,370 |
| 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R61DA061846 | Multilevel SUD and Overdose Prevention for Rural Youth Involved in County Legal Systems | 000 | 1 | NIH | 10/9/2024 | $0 |
| 2025 | 2024 | Seattle Children's Hospital | 4800 Sand Point Way NE | Seattle | WA | 98105-3916 | KING | USA | R01CE003623 | RFA-CE-23-006, Preventing firearm-related harm through Domestic Violence Protection Order firearm prohibitions and relinquishment | 02 | 2 | CDC | 11/12/2024 | $0 |
| 2025 | 2024 | Seattle Children's Hospital | 4800 Sand Point Way NE | Seattle | WA | 98105-3916 | KING | USA | R01CE003623 | RFA-CE-23-006, Preventing firearm-related harm through Domestic Violence Protection Order firearm prohibitions and relinquishment | 01 | 2 | CDC | 10/31/2024 | $0 |
| 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01DK129211 | Puberty, diabetes, and the kidneys, when eustress becomes distress | 001 | 4 | NIH | 11/18/2024 | $357,680 |
| 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI132819 | Mechanisms of T Cell Quiescence and Exhaustion | 001 | 5 | NIH | 11/20/2024 | $244,198 |
| 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R35GM139566 | Volatile Anesthetics and Metabolism | 000 | 4 | NIH | 11/15/2024 | $0 |
| 2025 | 2023 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AR073938 | B cell costimulatory signals in the pathogenesis of SLE | 000 | 5 | NIH | 10/29/2024 | -$68,460 |
| 2025 | 2023 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R03TR004179 | Defining the MAST4 interactome in brain development and epilepsy | 000 | 1 | NIH | 10/16/2024 | $0 |
| 2025 | 2023 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | F32HL154558 | Rhythmogenic states of the respiratory network reveal differential opioid sensitivity | 000 | 3 | NIH | 10/23/2024 | -$13,413 |
| 2025 | 2023 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R34MH123598 | Exploring Mechanisms of Change in a Pilot Trial of the RUBI Program in Educational Settings | 000 | 3 | NIH | 10/11/2024 | $0 |
| 2025 | 2023 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01MH118313 | 1/2 Treating Mothers with ADHD and their Young Children Via Telehealth: A Hybrid Type I Effectiveness-Implementation Trial | 002 | 5 | NIH | 10/24/2024 | -$661,289 |
| 2025 | 2023 | Seattle Children's Hospital | 4800 Sand Point Way NE | Seattle | WA | 98105-3916 | KING | USA | R01CE003623 | RFA-CE-23-006, Preventing firearm-related harm through Domestic Violence Protection Order firearm prohibitions and relinquishment | 02 | 2 | CDC | 11/12/2024 | $0 |
| 2025 | 2023 | Seattle Children's Hospital | 4800 Sand Point Way NE | Seattle | WA | 98105-3916 | KING | USA | R01CE003623 | RFA-CE-23-006, Preventing firearm-related harm through Domestic Violence Protection Order firearm prohibitions and relinquishment | 01 | 2 | CDC | 10/31/2024 | $0 |
| 2025 | 2022 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R33CA218592 | Preschoolers Learning & Active in Play (PLAY) | 000 | 5 | NIH | 10/30/2024 | $0 |
| 2025 | 2022 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AR073780 | Mechanisms of transition from acute to chronic pain in youth undergoing musculoskeletal surgery | 000 | 5 | NIH | 10/29/2024 | -$5,456 |
| 2025 | 2022 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01MH118313 | 1/2 Treating Mothers with ADHD and their Young Children Via Telehealth: A Hybrid Type I Effectiveness-Implementation Trial | 001 | 4 | NIH | 10/24/2024 | -$22,386 |
| 2025 | 2022 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01MH118313 | 1/2 Treating Mothers with ADHD and their Young Children Via Telehealth: A Hybrid Type I Effectiveness-Implementation Trial | 000 | 4 | NIH | 10/24/2024 | -$155,751 |
| 2025 | 2022 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R21MH126244 | Investigating the cellular and molecular neuropathology of the cerebellum in autism | 000 | 2 | NIH | 10/15/2024 | -$892 |
| 2025 | 2022 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R21NS117848 | High resolution analysis of human cerebellar neurogenesis | 000 | 2 | NIH | 11/19/2024 | $0 |
| 2025 | 2022 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI132819 | Mechanisms of T Cell Quiescence and Exhaustion | 000 | 4 | NIH | 11/20/2024 | -$244,198 |
| 2025 | 2020 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | UH3HD102038 | Prevalence and predictors of opioid misuse after adolescent spinal fusion surgery | 000 | 2 | NIH | 10/1/2024 | -$29,053 |
| 2025 | 2019 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | UG3HD102038 | Effectiveness of an mHealth psychosocial intervention to prevent transition from acute to chronic postsurgical pain in adolescents | 000 | 1 | NIH | 10/1/2024 | -$104,648 |
| 2025 | 2018 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | U01CA232490 | Combinations of Synergistic Bispecific Human Antibodies: A Novel Strategy for the Treatment of Neuroblastoma | 000 | 2 | NIH | 10/30/2024 | -$1 |
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| Issue Date FY: 2024 ( Subtotal = $102,829,558 ) (Continued on the next page) |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI182006 | Targeting protein secretion in Mycobacterium tuberculosis | 001 | 1 | NIH | 9/3/2024 | $90,271 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL126523 | Unraveling respiratory rhythm generation in medullary and supramedullary networks | 005 | 9 | NIH | 9/6/2024 | $3,677 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL126523 | Unraveling respiratory rhythm generation in medullary and supramedullary networks | 003 | 9 | NIH | 7/12/2024 | $0 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL126523 | Unraveling respiratory rhythm generation in medullary and supramedullary networks | 001 | 9 | NIH | 4/8/2024 | $858,263 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | P01HD104435 | Utilization of Advanced Technologies for the Understanding of Human Structural Birth Defects | 001 | 4 | NIH | 5/1/2024 | $144,355 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01MH135568 | Atypical Development in Infants and Toddlers: Computational Attentional Signatures through Mobile Eye Tracking | 001 | 1 | NIH | 4/30/2024 | $88,712 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL126523 | Unraveling respiratory rhythm generation in medullary and supramedullary networks | 002 | 9 | NIH | 6/7/2024 | $95,365 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI182006 | Targeting protein secretion in Mycobacterium tuberculosis | 000 | 1 | NIH | 2/29/2024 | $812,430 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | P01HD104435 | Utilization of Advanced Technologies for the Understanding of Human Structural Birth Defects | 000 | 4 | NIH | 12/21/2023 | $1,443,563 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01MH135568 | Atypical Development in Infants and Toddlers: Computational Attentional Signatures through Mobile Eye Tracking | 000 | 1 | NIH | 12/7/2023 | $798,405 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI132819 | Mechanisms of T Cell Quiescence and Exhaustion | 004 | 5 | NIH | 9/4/2024 | $64,595 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | F32HL159904 | Dynamic switching in the brainstem: a spatiotemporal mechanism for the neural control of breathing | 001 | 3 | NIH | 8/29/2024 | $4,964 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R03DK134746 | The role of SH2B3 in regulating CD8 T cells in Type 1 Diabetes | 001 | 2 | NIH | 5/2/2024 | $8,860 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R03DK134746 | The role of SH2B3 in regulating CD8 T cells in Type 1 Diabetes | 000 | 2 | NIH | 1/29/2024 | $132,908 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K08HS029028 | Using telehealth to improve access to gender-affirming care for BIPOC and rural gender diverse youth | 001 | 2 | AHRQ | 3/20/2024 | $142,182 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI132819 | Mechanisms of T Cell Quiescence and Exhaustion | 003 | 5 | NIH | 12/7/2023 | $0 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI132819 | Mechanisms of T Cell Quiescence and Exhaustion | 001 | 5 | NIH | 12/6/2023 | $581,363 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R50CA275857 | Pediatric brain tumors: Improving survival through integration of clinical molecular diagnostics and biologically targeted therapies into clinical trials | 000 | 2 | NIH | 2/29/2024 | $175,338 |
| 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K99AG080034 | Exploring brain perivascular fibroblasts in health and cerebral amyloid angiopathy | 000 | 2 | NIH | 7/31/2024 | $131,733 |
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