| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2025 ( Subtotal = $122,454,241 ) (Continued on the next page) |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | U01AI165455 | Collective Responses to Malaria Vaccination | 000 | 4 | NIH | 1/16/2025 | $679,001 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD109089 | Bifidobacterium infantis supplementation in early life to improve immunity in infants exposed to HIV: a randomized, placebo-controlled, double-blind trial | 002 | 4 | NIH | 8/11/2025 | $82,137 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD109089 | Bifidobacterium infantis supplementation in early life to improve immunity in infants exposed to HIV: a randomized, placebo-controlled, double-blind trial | 001 | 4 | NIH | 8/4/2025 | $65,880 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD109089 | Bifidobacterium infantis supplementation in early life to improve immunity in infants exposed to HIV: a randomized, placebo-controlled, double-blind trial | 000 | 4 | NIH | 7/17/2025 | $695,796 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DA056370 | Regulation of Opioid Sensitivity and Tolerance by Ubiquitin Ligase Signaling | 000 | 4 | NIH | 5/16/2025 | $605,352 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | F32NS143860 | Brainstem control of apneic reflexes relating to respiratory deaths in neurological disorders | 001 | 1 | NIH | 7/30/2025 | $0 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | F32NS143860 | Brainstem control of apneic reflexes relating to respiratory deaths in neurological disorders | 000 | 1 | NIH | 7/30/2025 | $74,632 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K99HD120649 | The role of prenatal nutrition in placental gene regulation and spontaneous preterm birth | 000 | 1 | NIH | 9/23/2025 | $259,076 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD111410 | Development of a Multiplex Proteomics Assay for High-Throughput Newborn Screening of a New Set of Treatable Neonatal Diseases | 001 | 3 | NIH | 6/18/2025 | $48,572 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HD111410 | Development of a Multiplex Proteomics Assay for High-Throughput Newborn Screening of a New Set of Treatable Neonatal Diseases | 000 | 3 | NIH | 2/12/2025 | $437,165 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD106628 | Supraphysiologic Shear Stresses Associated with Cardiopulmonary Bypass are Sufficient to Activate RIKP3 Signaling | 001 | 4 | NIH | 4/16/2025 | $77,073 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD106628 | Supraphysiologic Shear Stresses Associated with Cardiopulmonary Bypass are Sufficient to Activate RIKP3 Signaling | 000 | 4 | NIH | 2/18/2025 | $693,654 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01MH108519 | Regulation of mTOR signaling in the developing cerebral cortex as a point of convergence for multiple autism risk factors | 002 | 11 | NIH | 3/5/2025 | $415,863 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD116748 | Understanding Longitudinal Relationships between Sleep and Menstrual Pain in Adolescents | 000 | 1 | NIH | 8/8/2025 | $762,550 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | U01DA060443 | Deep Analysis of Transcriptome to Understand the Genetics of Substance Use Disorders in Rats | 000 | 1 | NIH | 6/27/2025 | $944,888 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AI185053 | Elucidating and targeting Siglec-9 function on mast cells | 000 | 1 | NIH | 7/23/2025 | $612,917 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | T32GM156698 | Invent@SC Clinical Pharmacology of Biotherapeutics | 000 | 1 | NIH | 7/17/2025 | $166,192 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K23HD100566 | Clinical factors associated with long-term recovery following pediatric critical illness and injury | 002 | 5 | NIH | 4/10/2025 | $155,736 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01NS143924 | Modeling mTOR network dynamics to achieve optimal drug rescue of congenital mTORopathies | 000 | 1 | NIH | 6/26/2025 | $754,066 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | UH3OD035508 | Mediators and Modifiers of Prenatal Environmental Exposures and Child Neurodevelopment: DNA methylation, Prenatal Diet, and Cognitive Stimulation (MEND) | 001 | 3 | NIH | 8/26/2025 | $984,226 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | UH3OD035508 | Mediators and Modifiers of Prenatal Environmental Exposures and Child Neurodevelopment: DNA methylation, Prenatal Diet, and Cognitive Stimulation (MEND) | 000 | 3 | NIH | 8/8/2025 | $328,076 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K08HL179396 | Circadian Regulation of Epithelial Immune Reponses in Asthma | 000 | 1 | NIH | 8/23/2025 | $154,980 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R21CA296748 | Developing Multispecific T cell Engaging Therapy for Mixed Phenotype Acute Leukemia | 000 | 1 | NIH | 8/26/2025 | $434,361 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01NS117434 | Endotelin-1 role in development and regeneration | 003 | 6 | NIH | 6/19/2025 | $615,241 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01MD015723 | The Family Bridge Program to Improve Communication and Navigation-Related Outcomes for Minority Children and Families: A Randomized Controlled Trial | 001 | 4 | NIH | 4/17/2025 | $779,022 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DE033703 | Leveraging Data for Infants with Cleft to Grow and Flourish: The BLOOM Study | 004 | 2 | NIH | 8/14/2025 | $0 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DE033703 | Leveraging Data for Infants with Cleft to Grow and Flourish: The BLOOM Study | 003 | 2 | NIH | 8/12/2025 | $0 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DE033703 | Leveraging Data for Infants with Cleft to Grow and Flourish: The BLOOM Study | 002 | 2 | NIH | 5/9/2025 | $85,895 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DE033703 | Leveraging Data for Infants with Cleft to Grow and Flourish: The BLOOM Study | 001 | 2 | NIH | 4/18/2025 | $773,066 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI163160 | Dysregulated asthmatic epithelial interferon responses to viruses drive exacerbation, T2 inflammation, and airway remodeling | 000 | 4 | NIH | 1/23/2025 | $838,670 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI155536 | Structural Analysis and Inhibitor Optimization of Cryptosporidium n-myristoyltransferase for Drug Discovery | 000 | 5 | NIH | 11/6/2024 | $800,512 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AG081840 | Pericyte control of capillary perfusion in the Alzheimer's disease brain | 000 | 3 | NIH | 2/14/2025 | $759,334 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R37NS109478 | Mechanisms of Oligodendrocyte and Axonal Abnormalities After Perinatal Brain Injury | 003 | 8 | NIH | 8/6/2025 | $455,000 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AG081840 | Pericyte control of capillary perfusion in the Alzheimer's disease brain | 001 | 3 | NIH | 8/11/2025 | $67,496 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R35GM139566 | Volatile Anesthetics and Metabolism | 002 | 5 | NIH | 9/1/2025 | $81,997 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R35GM139566 | Volatile Anesthetics and Metabolism | 001 | 5 | NIH | 2/20/2025 | $737,978 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K08CA277014 | Investigating SLC46A3 as a negative regulator of nanoparticle drug delivery | 004 | 3 | NIH | 8/22/2025 | $230,947 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R37NS095733 | Pathological Mechanisms of Human Cerebellar Malformations | 000 | 10 | NIH | 8/6/2025 | $967,274 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R61NS137365 | Chemogenetic Mouse Models for Cerebral Hypoperfusion and VCID | 000 | 2 | NIH | 7/10/2025 | $651,614 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K08DK138302 | Epigenetic regulation of kidney regeneration | 000 | 2 | NIH | 5/29/2025 | $154,980 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI182006 | Targeting protein secretion in Mycobacterium tuberculosis | 000 | 2 | NIH | 12/27/2024 | $861,105 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | F31EY035932 | Control of retinal cell fate specification by the miR9-2 disease gene locus | 000 | 2 | NIH | 7/31/2025 | $44,732 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | P01HD104435 | Utilization of Advanced Technologies for the Understanding of Human Structural Birth Defects | 001 | 5 | NIH | 4/15/2025 | $160,393 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | P01HD104435 | Utilization of Advanced Technologies for the Understanding of Human Structural Birth Defects | 000 | 5 | NIH | 12/18/2024 | $1,443,565 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL163103 | Hexosamine biosynthesis pathway metabolism during cardiac hypertrophy | 000 | 3 | NIH | 11/13/2024 | $735,425 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HL163103 | Hexosamine biosynthesis pathway metabolism during cardiac hypertrophy | 001 | 3 | NIH | 9/23/2025 | $81,713 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HS029142 | Development and Evaluation of an Instrument to Measure Shared Decision-Making in Pediatrics | 000 | 3 | AHRQ | 6/6/2025 | $386,987 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD116794 | Randomized trial of a shared decision-making intervention for families about firearm storage | 000 | 1 | NIH | 8/27/2025 | $754,584 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K23AI193246 | Respiratory Syncytial virus specific immunity in hematopoietic cell transplant recipients | 000 | 1 | NIH | 8/29/2025 | $182,726 |
|
