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 | Issue Date FY: 2025 ( Subtotal = $17,018,414 ) (Continued on the next page) |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | U01AI155335 | Biologically informed design of CD8+ T cell-dependent pre-erythrocytic stage malaria vaccines | 000 | 5 | NIH | 12/20/2024 | $1,204,933 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 Sand Point Way NE | Seattle | WA | 98105-3916 | KING | USA | T2331575 | Children's Hospitals Graduate Medical Education Payment Program | 00 | 8 | HRSA | 12/9/2024 | $625,920 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 Sand Point Way NE | Seattle | WA | 98105-3916 | KING | USA | T2331575 | Children's Hospitals Graduate Medical Education Payment Program | 00 | 8 | HRSA | 12/9/2024 | $1,115,376 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R21CA280139 | Identifying non-cardiotoxic drug combinations for patients with relapsed sarcoma | 000 | 2 | NIH | 1/15/2025 | $207,115 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI172824 | Parasite and host cell factors involved in the formation and persistence of Plasmodium vivax hypnozoites | 000 | 3 | NIH | 1/16/2025 | $742,943 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01DE032663 | Influence of viral and immune interventions on early events following oral SIV infection | 000 | 3 | NIH | 1/15/2025 | $717,601 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AR075813 | Impact of Loss-of-function NADPH Oxidase Variants on B cell Activation in SLE | 000 | 5 | NIH | 1/9/2025 | $482,898 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | U01AI165455 | Collective Responses to Malaria Vaccination | 000 | 4 | NIH | 1/16/2025 | $679,001 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K01AI187782 | Mechanisms of Innate Immune Activation in Mitochondrial Disease Onset and Progression | 000 | 1 | NIH | 12/11/2024 | $122,562 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K08AI166072 | Dissecting the molecular regulation of T cell localization and function within the Mycobacterium tuberculosis granuloma | 000 | 4 | NIH | 12/12/2024 | $184,917 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K99AI182458 | Elucidating a novel respiratory-mammary axis of T cell immunity | 000 | 1 | NIH | 12/16/2024 | $114,976 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AR076978 | Three-model platform for understanding DMD epigenetic mechanisms and advancing small molecule therapies | 000 | 5 | NIH | 12/20/2024 | $490,752 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01MH135568 | Atypical Development in Infants and Toddlers: Computational Attentional Signatures through Mobile Eye Tracking | 000 | 2 | NIH | 11/22/2024 | $754,007 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI180452 | Transporter function of the Mycobacterium tuberculosis PE/PPE proteins | 000 | 2 | NIH | 12/3/2024 | $857,231 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL166317 | Unraveling a parabrachial circuit for the state-dependent control of rapid breathing | 000 | 3 | NIH | 11/26/2024 | $797,260 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R25NS141155 | Summer Undergraduate Program to Advance Research and Equity in Pain and Neurological Health | 000 | 1 | NIH | 12/3/2024 | $129,113 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI155536 | Structural Analysis and Inhibitor Optimization of Cryptosporidium n-myristoyltransferase for Drug Discovery | 000 | 5 | NIH | 11/6/2024 | $800,512 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL163103 | Hexosamine biosynthesis pathway metabolism during cardiac hypertrophy | 000 | 3 | NIH | 11/13/2024 | $735,425 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI188789 | Species-transcending prevention of mosquito vector infection | 000 | 1 | NIH | 11/14/2024 | $832,071 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01ES033785 | Assessing how Prenatal Phthalate Exposure Disrupts Placental Transcriptional Regulation and Contributes to Changes in Gestational Length | 001 | 3 | NIH | 10/30/2024 | $101,793 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01ES033785 | Assessing how Prenatal Phthalate Exposure Disrupts Placental Transcriptional Regulation and Contributes to Changes in Gestational Length | 000 | 3 | NIH | 10/29/2024 | $675,801 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI182006 | Targeting protein secretion in Mycobacterium tuberculosis | 000 | 2 | NIH | 12/27/2024 | $861,105 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI170914 | Functional exploration of a deep Mycobacterium tuberculosis phosphoproteome | 000 | 3 | NIH | 12/19/2024 | $575,240 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K24AR085177 | Mentoring the next generation of researchers in pediatric autoimmunity | 000 | 1 | NIH | 1/19/2025 | $212,574 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI183642 | Targeted vaccines against pulmonary NTM infections in vulnerable populations | 000 | 1 | NIH | 12/20/2024 | $950,092 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI158536 | Uncovering the parasite and host determinants of Plasmodium vivax hypnozoite formation and development using single cell sequencing and human liver-chimeric mice | 000 | 4 | NIH | 1/6/2025 | $761,655 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | P01HD104435 | Utilization of Advanced Technologies for the Understanding of Human Structural Birth Defects | 000 | 5 | NIH | 12/18/2024 | $1,443,565 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01MH113545 | Investigating the synaptic pathology of Autism | 000 | 8 | NIH | 1/3/2025 | $661,502 |
| | 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | U54AI170855 | Behavior of HIV in Viral Environments (B-HIVE) | 000 | 3 | NIH | 1/15/2025 | $0 |
| | 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | UM1DA058220 | 'Mosaicism in Human Tissues, from Telomere to Telomere to RFA-22-013: "Somatic Mosaicism across Human Tissues Program: Genome Characterization Centers." | 000 | 2 | NIH | 1/9/2025 | $0 |
| | 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R21HL172011 | Computer-Vision and Computational Fluid Dynamics Analysis Pipeline to Improve Diagnosis in Pediatric Subglottic Stenosis | 001 | 2 | NIH | 12/4/2024 | $233,250 |
| | 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | U01DK084575 | Continuation of the Childhood Liver Disease Research Network - Seattle Clinical Center | 001 | 16 | NIH | 12/4/2024 | $263,075 |
| | 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01DA048036 | Molecular genetic mechanisms of opioid receptor signaling | 002 | 7 | NIH | 12/6/2024 | $81,287 |
| | 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01DA048036 | Molecular genetic mechanisms of opioid receptor signaling | 002 | 7 | NIH | 12/6/2024 | $18,081 |
| | 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI132819 | Mechanisms of T Cell Memory Quiescence | 001 | 5 | NIH | 11/20/2024 | $244,198 |
| | 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R35GM139566 | Volatile Anesthetics and Metabolism | 000 | 4 | NIH | 11/15/2024 | $0 |
| | 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01DK129211 | Puberty, diabetes, and the kidneys, when eustress becomes distress | 001 | 4 | NIH | 11/18/2024 | $357,680 |
| | 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K01MD019730 | Youth climate activism on social media: Building psychosocial resilienceamong minority youth | 003 | 2 | NIH | 1/16/2025 | $1 |
| | 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K01MD019730 | Youth climate activism on social media: Building psychosocial resilienceamong minority youth | 001 | 2 | NIH | 11/1/2024 | $127,370 |
| | 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R61DA061846 | Multilevel SUD and Overdose Prevention for Rural Youth Involved in County Legal Systems | 001 | 1 | NIH | 12/3/2024 | $0 |
| | 2025 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R61DA061846 | Multilevel SUD and Overdose Prevention for Rural Youth Involved in County Legal Systems | 000 | 1 | NIH | 10/9/2024 | $0 |
| | 2025 | 2024 | Seattle Children's Hospital | 4800 Sand Point Way NE | Seattle | WA | 98105-3916 | KING | USA | R01CE003623 | RFA-CE-23-006, Preventing firearm-related harm through Domestic Violence Protection Order firearm prohibitions and relinquishment | 02 | 2 | CDC | 11/12/2024 | $0 |
| | 2025 | 2024 | Seattle Children's Hospital | 4800 Sand Point Way NE | Seattle | WA | 98105-3916 | KING | USA | R01CE003623 | RFA-CE-23-006, Preventing firearm-related harm through Domestic Violence Protection Order firearm prohibitions and relinquishment | 01 | 2 | CDC | 10/31/2024 | $0 |
| | 2025 | 2023 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | U01DK084575 | Continuation of the Childhood Liver Disease Research Network - Seattle Clinical Center | 000 | 15 | NIH | 12/4/2024 | -$263,075 |
| | 2025 | 2023 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01DA048036 | Molecular genetic mechanisms of opioid receptor signaling | 001 | 6 | NIH | 12/6/2024 | -$18,081 |
| | 2025 | 2023 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01DA048036 | Molecular genetic mechanisms of opioid receptor signaling | 000 | 6 | NIH | 12/6/2024 | -$81,287 |
| | 2025 | 2023 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K23HL133437 | Risk Factors For Worse Lung Function iIn Latinos With Cystic Fibrosis | 001 | 6 | NIH | 11/29/2024 | $93,871 |
| | 2025 | 2023 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | F31AI167494 | Characterization of P. falciparum gametocyte-essential genes using a novel genetic screen | 000 | 2 | NIH | 11/27/2024 | -$2,309 |
| | 2025 | 2023 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL151389 | Neuroglial interactions underlying the generation of the sigh | 001 | 4 | NIH | 12/24/2024 | $0 |
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