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 | Issue Date FY: 2024 ( Subtotal = $40,218,745 ) (Continued on the next page) |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01GM140287 | Haplotype-aware models of gene and isoform expression with application to genetic studies of disease in diverse populations | 002 | 4 | NIH | 11/17/2023 | $650,806 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K23HD103872 | Improving Diversity in Neonatal Clinical Trial Enrollment | 000 | 4 | NIH | 4/11/2024 | $160,283 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | P01HD104435 | Utilization of Advanced Technologies for the Understanding of Human Structural Birth Defects | 000 | 4 | NIH | 12/21/2023 | $1,443,563 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R35GM139566 | Volatile Anesthetics and Metabolism | 000 | 4 | NIH | 2/6/2024 | $737,978 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AR076978 | Three-model platform for understanding DMD epigenetic mechanisms and advancing small molecule therapies | 000 | 4 | NIH | 12/4/2023 | $490,752 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | U01AI155335 | Biologically informed design of CD8+ T cell-dependent pre-erythrocytic stage malaria vaccines | 000 | 4 | NIH | 1/12/2024 | $1,117,978 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI155536 | Structural Analysis and Inhibitor Optimization of Cryptosporidium n-myristoyltransferase for Drug Discovery | 000 | 4 | NIH | 11/16/2023 | $767,617 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AG062738 | Pericyte structural plasticity and cerebrovascular health | 001 | 5 | NIH | 3/22/2024 | $50,029 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AG062738 | Pericyte structural plasticity and cerebrovascular health | 000 | 5 | NIH | 3/19/2024 | $505,860 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HD101471 | Enhancing Efficacy of Migraine Self-Management in Children with Comorbid Insomnia | 000 | 5 | NIH | 4/1/2024 | $532,642 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01CA240985 | Quantitative protein network profiling to improve CAR design and efficacy | 001 | 5 | NIH | 4/19/2024 | $24,507 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01CA240985 | Quantitative protein network profiling to improve CAR design and efficacy | 000 | 5 | NIH | 3/28/2024 | $441,113 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01DE029510 | Craniofacial microsomia: Accelerating Research and Education (CARE) | 002 | 5 | NIH | 4/5/2024 | $484,554 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI152268 | FXIIIA production by mast cells for innate immunity | 000 | 5 | NIH | 3/14/2024 | $747,959 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K24AI150991 | Clinical Impacts of Heterogeneous Interferon Responses to Viral Infection by Asthmatic Airway Epithelium | 000 | 5 | NIH | 1/19/2024 | $184,530 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI132819 | Mechanisms of T Cell Quiescence and Exhaustion | 003 | 5 | NIH | 12/7/2023 | $0 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI132819 | Mechanisms of T Cell Quiescence and Exhaustion | 001 | 5 | NIH | 12/6/2023 | $581,363 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 Sand Point Way NE | Seattle | WA | 98105-3916 | KING | USA | T2331575 | Children's Hospitals Graduate Medical Education Payment Program | 02 | 7 | HRSA | 3/7/2024 | $157,004 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 Sand Point Way NE | Seattle | WA | 98105-3916 | KING | USA | T2331575 | Children's Hospitals Graduate Medical Education Payment Program | 02 | 7 | HRSA | 3/7/2024 | $273,960 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 Sand Point Way NE | Seattle | WA | 98105-3916 | KING | USA | T2331575 | Children's Hospitals Graduate Medical Education Payment Program | 01 | 7 | HRSA | 1/29/2024 | $714,368 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 Sand Point Way NE | Seattle | WA | 98105-3916 | KING | USA | T2331575 | Children's Hospitals Graduate Medical Education Payment Program | 01 | 7 | HRSA | 1/29/2024 | $1,246,515 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R00NS112575 | Dissecting the Action Learning Process with Dopaminergic Reinforcement | 000 | 3 | NIH | 2/29/2024 | $224,097 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R03NS135446 | Brain Tumor CAR T Mouse Model | 000 | 1 | NIH | 1/18/2024 | $98,450 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI182006 | Targeting protein secretion in Mycobacterium tuberculosis | 000 | 1 | NIH | 2/29/2024 | $812,430 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI180452 | Transporter function of the Mycobacterium tuberculosis PE/PPE proteins | 000 | 1 | NIH | 2/6/2024 | $821,841 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R21HS029399 | Inform Shared Decision-making with Advanced Bayesian Causal Inference to Improve Quality of Pediatric Rheumatology Care | 000 | 2 | AHRQ | 4/10/2024 | $123,050 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R21CA280139 | Identifying non-cardiotoxic drug combinations for patients with relapsed sarcoma | 000 | 1 | NIH | 2/16/2024 | $276,152 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R21CA280726 | Designing inducible chemotactic beacons for enhanced trafficking of CAR T cells to solid tumors | 000 | 1 | NIH | 4/1/2024 | $230,127 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | F32HL172607 | Spatial Heterogeneity in PIK3CA-Mutated Lymphatic Malformations | 000 | 1 | NIH | 11/20/2023 | $61,860 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01MH135568 | Atypical Development in Infants and Toddlers: Computational Attentional Signatures through Mobile Eye Tracking | 000 | 1 | NIH | 12/7/2023 | $798,405 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R00CA263161 | Characterizing the role of MARCH5 in apoptosis regulation in acute myeloid leukemia | 000 | 3 | NIH | 4/10/2024 | $248,983 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K99HL168211 | Unraveling the Mechanisms of Opioid-Induced Airway Constriction: A Path towards Novel Therapeutics for Opioid Overdose | 000 | 1 | NIH | 3/25/2024 | $123,212 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL170607 | Mechanisms by which red blood cells contribute cardiopulmonary bypass associated inflammation | 000 | 1 | NIH | 4/16/2024 | $895,205 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01DK136980 | Interrogating The Biology Of Human Lupus Nephritis Using Single Cell Resolution Spatial Transcriptomics | 000 | 1 | NIH | 3/22/2024 | $851,374 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R21AI178335 | Calcium signaling in Mycobacterium tuberculosis | 000 | 2 | NIH | 4/10/2024 | $235,775 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HD111410 | Development of a Multiplex Proteomics Assay for High-Throughput Newborn Screening of a New Set of Treatable Neonatal Diseases | 000 | 2 | NIH | 2/7/2024 | $503,458 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI177257 | Perturbations of host cell signaling by a complex hepatotropic pathogen | 000 | 12 | NIH | 1/16/2024 | $580,903 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R37CA266777 | The IL-18-IFN? axis predicts response to immunotherapy | 000 | 2 | NIH | 3/22/2024 | $716,362 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R21DE031942 | In vivo two-photon imaging of?vascular invasion and stem cell translocation in calvarial bone | 000 | 2 | NIH | 4/17/2024 | $221,513 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI172824 | Parasite and host cell factors involved in the formation and persistence of?Plasmodium vivax?hypnozoites | 000 | 2 | NIH | 1/12/2024 | $713,088 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AG081840 | Pericyte control of capillary perfusion in the Alzheimer's disease brain | 000 | 2 | NIH | 1/29/2024 | $756,120 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R50CA275857 | Pediatric brain tumors: Improving survival through integration of clinical molecular diagnostics and biologically targeted therapies into clinical trials | 000 | 2 | NIH | 2/29/2024 | $175,338 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K01DA058543 | Dissociating respiratory depression and analgesia via a data-driven model of interacting respiratory and pain networks | 000 | 2 | NIH | 3/13/2024 | $94,062 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01DE032663 | Influence of viral and immune interventions on early events following oral SIV infection | 000 | 2 | NIH | 12/6/2023 | $726,505 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01ES033785 | Assessing how Prenatal Phthalate Exposure Disrupts Placental Transcriptional Regulation and Contributes to Changes in Gestational Length | 001 | 2 | NIH | 10/31/2023 | $70,544 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01ES033785 | Assessing how Prenatal Phthalate Exposure Disrupts Placental Transcriptional Regulation and Contributes to Changes in Gestational Length | 000 | 2 | NIH | 10/26/2023 | $723,130 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL166317 | Unraveling a parabrachial circuit for the state-dependent control of rapid breathing | 000 | 2 | NIH | 12/15/2023 | $760,829 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R03DK134746 | The role of SH2B3 in regulating CD8 T cells in Type 1 Diabetes | 000 | 2 | NIH | 1/29/2024 | $132,908 |
| | 2024 | 2024 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL163103 | Hexosamine biosynthesis pathway metabolism during cardiac hypertrophy | 000 | 2 | NIH | 11/6/2023 | $764,056 |
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