| | | | | | | | | | | | | | | | |
| | |
 | Issue Date FY: 2025 ( Subtotal = $58,891,497 ) (Continued on the next page) |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HL170607 | Mechanisms by which red blood cells contribute cardiopulmonary bypass associated inflammation | 000 | 2 | NIH | 4/3/2025 | $753,324 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K01AI187782 | Mechanisms of Innate Immune Activation in Mitochondrial Disease Onset and Progression | 000 | 1 | NIH | 12/11/2024 | $122,562 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DA048036 | Molecular genetic mechanisms of opioid receptor signaling | 003 | 8 | NIH | 4/18/2025 | $776,335 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R25NS141155 | Summer Undergraduate Program to Advance Research and Equity in Pain and Neurological Health | 000 | 1 | NIH | 12/3/2024 | $129,113 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL166317 | Unraveling a parabrachial circuit for the state-dependent control of rapid breathing | 000 | 3 | NIH | 11/26/2024 | $797,260 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI180452 | Transporter function of the Mycobacterium tuberculosis PE/PPE proteins | 000 | 2 | NIH | 12/3/2024 | $857,231 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01MH135568 | Atypical Development in Infants and Toddlers: Computational Attentional Signatures through Mobile Eye Tracking | 000 | 2 | NIH | 11/22/2024 | $754,007 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI188789 | Species-transcending prevention of mosquito vector infection | 000 | 1 | NIH | 11/14/2024 | $832,071 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K23HD103872 | Improving Diversity in Neonatal Clinical Trial Enrollment | 000 | 5 | NIH | 4/7/2025 | $159,764 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HL169793 | Gene Editing for Hemophilia A Treatment Using Lipid Nanoparticles | 000 | 2 | NIH | 5/20/2025 | $734,329 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R00NS112575 | Dissecting the Action Learning Process with Dopaminergic Reinforcement | 000 | 4 | NIH | 2/20/2025 | $224,094 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R35GM139566 | Volatile Anesthetics and Metabolism | 001 | 5 | NIH | 2/20/2025 | $737,978 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI158536 | Uncovering the parasite and host determinants of Plasmodium vivax hypnozoite formation and development using single cell sequencing and human liver-chimeric mice | 000 | 4 | NIH | 1/6/2025 | $761,655 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | K08AI166072 | Dissecting the molecular regulation of T cell localization and function within the Mycobacterium tuberculosis granuloma | 000 | 4 | NIH | 12/12/2024 | $184,917 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01HL163103 | Hexosamine biosynthesis pathway metabolism during cardiac hypertrophy | 000 | 3 | NIH | 11/13/2024 | $735,425 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HS029142 | Development and Evaluation of an Instrument to Measure Shared Decision-Making in Pediatrics | 000 | 3 | AHRQ | 6/6/2025 | $386,987 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | P01HD104435 | Utilization of Advanced Technologies for the Understanding of Human Structural Birth Defects | 001 | 5 | NIH | 4/15/2025 | $160,393 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | P01HD104435 | Utilization of Advanced Technologies for the Understanding of Human Structural Birth Defects | 000 | 5 | NIH | 12/18/2024 | $1,443,565 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI182006 | Targeting protein secretion in Mycobacterium tuberculosis | 000 | 2 | NIH | 12/27/2024 | $861,105 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R21CA280139 | Identifying non-cardiotoxic drug combinations for patients with relapsed sarcoma | 001 | 2 | NIH | 6/3/2025 | $23,012 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R21CA280139 | Identifying non-cardiotoxic drug combinations for patients with relapsed sarcoma | 000 | 2 | NIH | 1/15/2025 | $207,115 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AI181218 | Immunotherapeutic approach for the prevention of secondary infection with drug-resistant TB | 000 | 2 | NIH | 4/28/2025 | $978,349 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K99HL168211 | Unraveling the Mechanisms of Opioid-Induced Airway Constriction: A Path towards Novel Therapeutics for Opioid Overdose | 001 | 2 | NIH | 5/15/2025 | $0 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K99HL168211 | Unraveling the Mechanisms of Opioid-Induced Airway Constriction: A Path towards Novel Therapeutics for Opioid Overdose | 000 | 2 | NIH | 3/31/2025 | $120,269 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01ES033785 | Assessing how Prenatal Phthalate Exposure Disrupts Placental Transcriptional Regulation and Contributes to Changes in Gestational Length | 001 | 3 | NIH | 10/30/2024 | $101,793 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01ES033785 | Assessing how Prenatal Phthalate Exposure Disrupts Placental Transcriptional Regulation and Contributes to Changes in Gestational Length | 000 | 3 | NIH | 10/29/2024 | $675,801 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R50CA275857 | Pediatric brain tumors: Improving survival through integration of clinical molecular diagnostics and biologically targeted therapies into clinical trials | 000 | 3 | NIH | 3/13/2025 | $175,338 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | K23HD107232 | A Novel Photo-Narrative Communication Intervention Among Parents of Children with Severe Neurological Impairment in the ICU | 000 | 4 | NIH | 5/1/2025 | $159,005 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD114797 | Evaluating Huddles as a Novel Approach to Improving Concussion Safety | 000 | 1 | NIH | 5/7/2025 | $758,428 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AI170777 | Impairment of anti-Plasmodium T cell memory by type I Interferon Signaling | 001 | 3 | NIH | 5/15/2025 | $767,280 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | U01AI165455 | Collective Responses to Malaria Vaccination | 000 | 4 | NIH | 1/16/2025 | $679,001 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | U54AI170855 | Behavior of HIV in Viral Environments (B-HIVE) | 001 | 4 | NIH | 4/28/2025 | $5,862,824 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R03AI180586 | Cross development of surrogate efficacy mycobacterial growth inhibition assay endpoint for the translational guinea pig model | 000 | 2 | NIH | 4/25/2025 | $97,850 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AR076978 | Three-model platform for understanding DMD epigenetic mechanisms and advancing small molecule therapies | 001 | 5 | NIH | 4/30/2025 | $38,170 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AR076978 | Three-model platform for understanding DMD epigenetic mechanisms and advancing small molecule therapies | 000 | 5 | NIH | 12/20/2024 | $490,752 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DA056370 | Regulation of Opioid Sensitivity and Tolerance by Ubiquitin Ligase Signaling | 000 | 4 | NIH | 5/16/2025 | $605,352 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD107794 | Randomized controlled trial of an internet-based prevention intervention for young children at-risk for functional abdominal pain | 000 | 4 | NIH | 4/7/2025 | $640,526 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01NS122902 | A Bioengineering Approach to Develop a Laminar 3D Cerebellar Neuronal Circuit for Modeling Human Cerebellum | 000 | 4 | NIH | 4/9/2025 | $688,366 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R37CA289981 | B7-H3 CAR T cells following initial radiation for children and young adults with diffuse intrinsic pontine glioma | 000 | 1 | NIH | 5/26/2025 | $456,414 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AG077731 | Brain Drain: In Vivo Optical Interrogation of Venular Function in Gray and White Matter | 000 | 2 | NIH | 5/2/2025 | $699,961 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AG077731 | Brain Drain: In Vivo Optical Interrogation of Venular Function in Gray and White Matter | 001 | 2 | NIH | 6/10/2025 | $62,217 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01EY033364 | Optimizing Models of Non-Coding Genetic Risk in Age-Related Macular Degeneration | 000 | 4 | NIH | 2/14/2025 | $492,250 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01HD103700 | Brain Injury Outpatient Education and Care Navigation | 000 | 5 | NIH | 4/21/2025 | $589,533 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R21HD118297 | Use of Oscillometry for the Evaluation of Pulmonary Function Following Pediatric Acute Respiratory Failure. | 000 | 1 | NIH | 4/24/2025 | $224,083 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01AI165351 | Rapid disease progression and viral reservoir formation in SIV-infected infant macaques | 000 | 5 | NIH | 5/21/2025 | $871,114 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R01DE032663 | Influence of viral and immune interventions on early events following oral SIV infection | 001 | 3 | NIH | 5/5/2025 | $79,732 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R00CA263161 | Characterizing the role of MARCH5 in apoptosis regulation in acute myeloid leukemia | 001 | 4 | NIH | 5/22/2025 | $24,897 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3901 | KING | USA | R00CA263161 | Characterizing the role of MARCH5 in apoptosis regulation in acute myeloid leukemia | 000 | 4 | NIH | 3/14/2025 | $224,082 |
| | 2025 | 2025 | SEATTLE CHILDREN'S HOSPITAL | 4800 SAND POINT WAY NE | SEATTLE | WA | 98105-3916 | KING | USA | R01AI177257 | Perturbations of host cell signaling by a complex hepatotropic pathogen | 000 | 13 | NIH | 2/13/2025 | $663,183 |
|
