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 | Issue Date FY: 2025 ( Subtotal = $31,673,396 ) (Continued on the next page) |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01HL172846 | IL-1R1 in Endothelial-to-Mesenchymal Activation | 001 | 2 | NIH | 1/27/2025 | $410,370 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01HL156952 | Defective Zn Homeostasis impairs host defense against pneumococcal pneumonia | 000 | 4 | NIH | 12/5/2024 | $383,750 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01GM144414 | Insight into the mechanism of action of the SSB interactome | 000 | 4 | NIH | 1/27/2025 | $281,202 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01AR082148 | Effective local delivery of bone anabolic agent to accelerate the healing of delayed fracture union | 000 | 3 | NIH | 12/17/2024 | $396,894 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R00AG059947 | Behavioral and physiological linkage in people with frontotemporal dementia and spousal caregivers | 000 | 6 | NIH | 12/16/2024 | $212,304 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01HD116950 | RBC transfusion exacerbates brain inflammation in anemic murine neonates and causes long term neurodevelopment impairment | 000 | 1 | NIH | 12/17/2024 | $415,832 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | F30ES036063 | Targeting the ACOD1 immunometabolic pathway of lung myeloid cells to reduce environmental exposure-induced lung disease | 000 | 2 | NIH | 12/19/2024 | $37,727 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01AI168315 | Proteostasis in Plasmodium falciparum artemisinin resistance | 000 | 2 | NIH | 11/18/2024 | $747,604 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01AI145542 | Prodrug Formulations Create Sustained-Release Antiretrovirals | 001 | 6 | NIH | 11/18/2024 | $744,473 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01CA266759 | Nanomedicine of Hedgehog and AKT/ERK Dual Inhibitors for Pancreatic Cancer | 000 | 4 | NIH | 12/19/2024 | $397,903 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | P50AA030407 | Alcohol Center Of Research -- Nebraska (ACORN) | 000 | 3 | NIH | 1/17/2025 | $1,588,725 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01CA259080 | Preclinical development of a novel antibody conjugate for intraoperative detection of pancreatic cancer | 000 | 4 | NIH | 2/13/2025 | $320,687 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01HL168500 | Potential mechanism underlying parasympathetic neuronal dysfunction in diabetes | 000 | 2 | NIH | 1/17/2025 | $542,994 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 Nebraska Medical Center | OMAHA | NE | 68198-7835 | DOUGLAS | USA | H7600529 | Ryan White Part C Outpatient EIS Program | 00 | 26 | HRSA | 12/3/2024 | $235,528 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R61AI188553 | Dose flexible ultra-long-acting prodrug formulations for pediatric populations | 000 | 1 | NIH | 1/17/2025 | $300,000 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R61AI188553 | Dose flexible ultra-long-acting prodrug formulations for pediatric populations | 000 | 1 | NIH | 1/17/2025 | $678,661 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01CA295693 | Porcine Platforms For Technology Development In Pancreatic Cancer | 000 | 1 | NIH | 12/19/2024 | $635,749 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01DA060753 | Epigenetic regulation of astrocyte-specific NLRP6 inflammasome and PANoptosis in HIV Tat and methamphetamine-mediated neuroinflammation | 000 | 2 | NIH | 4/11/2025 | $509,793 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01CA290859 | Lysosome Trapped FAP-Targeted Theranostics for Pancreatic Cancer | 000 | 2 | NIH | 2/17/2025 | $564,044 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01HD115482 | Integrase Inhibitors during pregnancy and Neurodevelopmental Outcomes: Underlying Mechanism and Therapeutic Intervention | 000 | 2 | NIH | 4/11/2025 | $573,445 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01CA277495 | Regulation of RBP Function during EMT | 000 | 2 | NIH | 4/11/2025 | $378,188 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01AI169788 | T cell-innate immune crosstalk regulates Staphylococcus aureus craniotomy infection | 000 | 4 | NIH | 3/6/2025 | $563,390 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | UH3HL165740 | Behavioral Economic and Staffing Strategies To Increase Adoption of the ABCDEF Bundle in the ICU (BEST-ICU) | 000 | 3 | NIH | 3/27/2025 | $1,106,984 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | UH3HL165740 | Behavioral Economic and Staffing Strategies To Increase Adoption of the ABCDEF Bundle in the ICU (BEST-ICU) | 000 | 3 | NIH | 3/27/2025 | $200,000 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | K23MH125734 | Investigations of antiretroviral therapy penetration in cerebrospinal fluid | 000 | 5 | NIH | 4/4/2025 | $173,151 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01MH121402 | Targeted lipid nanoparticles for gene therapeutics delivery approach to eradicating HIV reservoirs | 001 | 6 | NIH | 4/16/2025 | $736,036 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01DK131990 | Gut bacterial metallophores in the development and severity of inflammatory bowel disease | 000 | 4 | NIH | 3/5/2025 | $587,908 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01CA258621 | Geranylgeranyl diphosphate synthase inhibitor therapy for multiple myeloma | 000 | 5 | NIH | 3/27/2025 | $452,780 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01DK135817 | Development and Preclinical Evaluation of Nanoformulations in Liver Fibrotic Mice | 000 | 3 | NIH | 2/26/2025 | $365,775 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01DA060755 | HIV Tat and Opiate-mediated aberrations in glial-neuronal crosstalk: Implications for the role of extracellular RNA in HAND | 000 | 2 | NIH | 4/10/2025 | $472,930 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01AG069609 | The Impact of Environmental Stressors on Chronic Disease Disparities in Women | 000 | 6 | NIH | 4/15/2025 | $545,460 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R35HL155460 | Harnessing Glycoproteomics and Glycomics to Understand Cardiac Biology and Disease | 000 | 5 | NIH | 4/22/2025 | $690,750 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01DA062274 | Molecular interplay of HIV Tat, cocaine, and cART in microglial pyroptosis: Role of NLRP3 inflammasome | 000 | 1 | NIH | 4/15/2025 | $441,154 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | F30AG084348 | Measuring neurodevelopmental effects of genetic risk for Alzheimer's disease via cross-sectional study of brain, cognitive, and physical fitness variables in periadolescent children | 000 | 2 | NIH | 4/18/2025 | $37,727 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01DA059874 | Cannabinoid inhibition of CNS inflammasome activation via modulation of the gut-brain axis | 000 | 1 | NIH | 4/14/2025 | $844,946 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01CA259168 | Development of an NTSR1-Targeted Radiotherapeutic for Colorectal Cancer | 000 | 5 | NIH | 3/14/2025 | $295,296 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R03DA060076 | Impact of cannabidiol on HIV infection and methamphetamine abuse associated neuroinflammation | 000 | 2 | NIH | 3/17/2025 | $153,500 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01AI158160 | LASER ART for PreP | 000 | 5 | NIH | 4/17/2025 | $698,744 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R00GM138920 | Genome-wide mechanisms and dynamics of ATP-dependent chromatin remodeling complexes | 000 | 5 | NIH | 3/31/2025 | $249,000 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R35ES031708 | Aberrant DNA Repair and Lupus | 002 | 6 | NIH | 4/14/2025 | $789,292 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R21AI180574 | Characterizing the Function of Cyclic di-AMP on Chlamydial Growth and Differentiation | 000 | 2 | NIH | 3/17/2025 | $186,119 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01NS034239 | Neuroprotective Immunity and HIV Dementia | 002 | 30 | NIH | 3/20/2025 | $690,748 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01NS137084 | Contribution of Glia to Sleep/Wake Disturbances in FXS | 000 | 1 | NIH | 3/28/2025 | $515,898 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01AI162964 | Mechanisms of staphylococcal skin colonization | 000 | 4 | NIH | 3/20/2025 | $524,998 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01DA059874 | Cannabinoid inhibition of CNS inflammasome activation via modulation of the gut-brain axis | 001 | 1 | NIH | 4/16/2025 | $0 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R61AI188553 | Dose flexible ultra-long-acting prodrug formulations for pediatric populations | 001 | 1 | NIH | 4/17/2025 | $250,000 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01CA260749 | UPR Activators for Cancer Therapy | 000 | 4 | NIH | 1/8/2025 | $316,018 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01HL160820 | Skeletal Muscle Nrf2: Exercise-Induced Cardiovascular Protection | 000 | 4 | NIH | 1/10/2025 | $466,635 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R21CA298918 | Flupirtine Analogue Synthesis and Screening for the Treatment of Chemotherapy-Induced Neuropathic Pain | 000 | 1 | NIH | 1/30/2025 | $179,403 |
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