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 | Issue Date FY: 2025 ( Subtotal = $22,370,444 ) (Continued on the next page) |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01GM145736 | Neuromuscular junction as a therapeutic target to improve post-traumatic outcomes | 000 | 4 | NIH | 3/25/2025 | $338,468 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01HL155439 | GATA Factor Mechanisms in Erythroid Regeneration | 000 | 5 | NIH | 12/21/2024 | $383,750 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01HL172846 | IL-1R1 in Endothelial-to-Mesenchymal Activation | 001 | 2 | NIH | 1/27/2025 | $410,370 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01HL156952 | Defective Zn Homeostasis impairs host defense against pneumococcal pneumonia | 000 | 4 | NIH | 12/5/2024 | $383,750 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01GM144414 | Insight into the mechanism of action of the SSB interactome | 000 | 4 | NIH | 1/27/2025 | $281,202 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01AI168315 | Proteostasis in Plasmodium falciparum artemisinin resistance | 000 | 2 | NIH | 11/18/2024 | $747,604 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | F30ES036063 | Targeting the ACOD1 immunometabolic pathway of lung myeloid cells to reduce environmental exposure-induced lung disease | 000 | 2 | NIH | 12/19/2024 | $37,727 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01HD116950 | RBC transfusion exacerbates brain inflammation in anemic murine neonates and causes long term neurodevelopment impairment | 000 | 1 | NIH | 12/17/2024 | $415,832 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01AI145542 | Prodrug Formulations Create Sustained-Release Antiretrovirals | 001 | 6 | NIH | 11/18/2024 | $744,473 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | P50AA030407 | Alcohol Center Of Research -- Nebraska (ACORN) | 000 | 3 | NIH | 1/17/2025 | $1,588,725 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01CA266759 | Nanomedicine of Hedgehog and AKT/ERK Dual Inhibitors for Pancreatic Cancer | 000 | 4 | NIH | 12/19/2024 | $397,903 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01CA259080 | Preclinical development of a novel antibody conjugate for intraoperative detection of pancreatic cancer | 000 | 4 | NIH | 2/13/2025 | $320,687 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01HL168500 | Potential mechanism underlying parasympathetic neuronal dysfunction in diabetes | 000 | 2 | NIH | 1/17/2025 | $542,994 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 Nebraska Medical Center | OMAHA | NE | 68198-7835 | DOUGLAS | USA | H7600529 | Ryan White Part C Outpatient EIS Program | 00 | 26 | HRSA | 12/3/2024 | $235,528 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R61AI188553 | Dose flexible ultra-long-acting prodrug formulations for pediatric populations | 000 | 1 | NIH | 1/17/2025 | $678,661 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R61AI188553 | Dose flexible ultra-long-acting prodrug formulations for pediatric populations | 000 | 1 | NIH | 1/17/2025 | $300,000 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01CA295693 | Porcine Platforms For Technology Development In Pancreatic Cancer | 000 | 1 | NIH | 12/19/2024 | $635,749 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R03CA297351 | Silencing B7-H3 mitigates tumor aggressiveness in group 3 medulloblastoma | 000 | 1 | NIH | 12/31/2024 | $76,750 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R21EY037036 | Using optical sensors to measure synaptic glutamate release from retinal rod photoreceptor cells | 000 | 1 | NIH | 12/30/2024 | $190,538 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | F99CA294241 | Tumor-cell intrinsic and extrinsic determinants of drug resistance and metastasis | 000 | 1 | NIH | 12/11/2024 | $3,000 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01HL171602 | Nrf2 and the exaggerated Exercise Pressor Reflex in Peripheral Arterial Disease | 000 | 2 | NIH | 11/22/2024 | $564,745 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R35GM152032 | DNA Replication Machines: Structure-Function Studies | 001 | 2 | NIH | 11/5/2024 | $455,895 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01AR082148 | Effective local delivery of bone anabolic agent to accelerate the healing of delayed fracture union | 000 | 3 | NIH | 12/17/2024 | $396,894 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01CA281044 | Fidelity Mechanisms of DNA Polymerase Beta | 000 | 2 | NIH | 3/3/2025 | $558,374 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01CA290859 | Lysosome Trapped FAP-Targeted Theranostics for Pancreatic Cancer | 000 | 2 | NIH | 2/17/2025 | $564,044 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01AI169788 | T cell-innate immune crosstalk regulates Staphylococcus aureus craniotomy infection | 000 | 4 | NIH | 3/6/2025 | $563,390 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | UH3HL165740 | Behavioral Economic and Staffing Strategies To Increase Adoption of the ABCDEF Bundle in the ICU (BEST-ICU) | 000 | 3 | NIH | 3/27/2025 | $1,106,984 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | UH3HL165740 | Behavioral Economic and Staffing Strategies To Increase Adoption of the ABCDEF Bundle in the ICU (BEST-ICU) | 000 | 3 | NIH | 3/27/2025 | $200,000 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01DK131990 | Gut bacterial metallophores in the development and severity of inflammatory bowel disease | 000 | 4 | NIH | 3/5/2025 | $587,908 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01CA258621 | Geranylgeranyl diphosphate synthase inhibitor therapy for multiple myeloma | 000 | 5 | NIH | 3/27/2025 | $452,780 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01DK135817 | Development and Preclinical Evaluation of Nanoformulations in Liver Fibrotic Mice | 000 | 3 | NIH | 2/26/2025 | $365,775 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R03DA060076 | Impact of cannabidiol on HIV infection and methamphetamine abuse associated neuroinflammation | 000 | 2 | NIH | 3/17/2025 | $153,500 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01CA259168 | Development of an NTSR1-Targeted Radiotherapeutic for Colorectal Cancer | 000 | 5 | NIH | 3/14/2025 | $295,296 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R21AI180574 | Characterizing the Function of Cyclic di-AMP on Chlamydial Growth and Differentiation | 000 | 2 | NIH | 3/17/2025 | $186,119 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01NS034239 | Neuroprotective Immunity and HIV Dementia | 002 | 30 | NIH | 3/20/2025 | $690,748 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01AI162964 | Mechanisms of staphylococcal skin colonization | 000 | 4 | NIH | 3/20/2025 | $524,998 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01HL160820 | Skeletal Muscle Nrf2: Exercise-Induced Cardiovascular Protection | 000 | 4 | NIH | 1/10/2025 | $466,635 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01CA260749 | UPR Activators for Cancer Therapy | 000 | 4 | NIH | 1/8/2025 | $316,018 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01DA060466 | Health Effects of E-cigarette Use on Brain Functions and Cognitive Development among Adolescents: A US Population-Based Study | 000 | 2 | NIH | 1/8/2025 | $330,956 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R21CA298918 | Flupirtine Analogue Synthesis and Screening for the Treatment of Chemotherapy-Induced Neuropathic Pain | 000 | 1 | NIH | 1/30/2025 | $179,403 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01MH132517 | PREVENTING ALZHEIMER’S DISEASE-LIKE BRAIN PATHOLOGY IN HIV INFECTION BY TARGETING CCR5 | 000 | 3 | NIH | 2/13/2025 | $587,137 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01NS116037 | Overcoming Resistance Mechanisms in Hedgehog and Myc-amplified Medulloblastoma | 000 | 5 | NIH | 11/29/2024 | $360,639 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R35GM147467 | Fine-Scale Genome Folding Relative to Transcription and Location | 000 | 3 | NIH | 12/6/2024 | $36,077 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | T32GM152775 | Critical Analysis of Data-Rich Networks for Biomedical Scientists in Training. | 000 | 2 | NIH | 1/15/2025 | $287,370 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01EB035543 | Theory Assisted Design, Synthesis and Biological Activity of Bacteria-Targeting Nanostructures | 000 | 1 | NIH | 1/15/2025 | $410,713 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01CA288372 | Targeting Disease Specific Tn Antigen in Pancreatic Cancer | 000 | 1 | NIH | 12/20/2024 | $578,998 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01CA241752 | Targeting MUC5AC mucin in breast cancer brain metastasis | 000 | 5 | NIH | 1/14/2025 | $415,170 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 987835 NEBRASKA MEDICAL CENTER | OMAHA | NE | 68198-7835 | DOUGLAS | USA | R01HL137832 | Mechanisms of cardiac sympathetic hyperactivity in chronic heart failure | 000 | 7 | NIH | 11/26/2024 | $580,561 |
| | 2025 | 2025 | BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 4215 EMILE ST | OMAHA | NE | 68105 | DOUGLAS | USA | R01HL157269 | Autophagy-mediated mucin degradation is necessary for resolution of mucous metaplasia | 000 | 5 | NIH | 3/25/2025 | $484,702 |
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