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 | Issue Date FY: 2025 ( Subtotal = $4,467,213 ) |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA268440 | High Throughput Screen for Inhibitors of the YEATS2 Histone Acylation Reader | 000 | 4 | NIH | 12/13/2024 | $391,163 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01MH139201 | The immunobiological mechanisms of depression in perimenopause | 000 | 1 | NIH | 12/20/2024 | $919,453 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AI165580 | Elucidating the Structural Mechanisms of NAIP Receptors in Bacterial Detection and Inflammasome Activation | 001 | 4 | NIH | 11/5/2024 | $465,600 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F99CA294248 | Determinants of susceptibility to pediatric acute myeloid leukemia | 000 | 1 | NIH | 12/6/2024 | $3,000 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | K99CA286742 | The role of AHR in modulatingimmunotherapy response and adverse events in bladder cancer | 000 | 2 | NIH | 1/6/2025 | $153,160 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01ES036051 | circSATB2, a novel regulator of arsenic-induced carcinogenesis | 000 | 2 | NIH | 11/5/2024 | $628,913 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | U01CA297713 | Dietary regulation of anti-tumor immunity through caloric restriction | 000 | 1 | NIH | 3/17/2025 | $767,324 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA276031 | Mechanisms of cancer mutations | 000 | 3 | NIH | 11/13/2024 | $434,294 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R25HG011020 | Epigenomics Workshop for Graduate Students | 000 | 4 | NIH | 11/6/2024 | $51,777 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35GM152081 | Mechanisms and Applications of RNA-mediated Enzymes in Translation and Immunity | 000 | 3 | NIH | 1/17/2025 | $563,163 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01ES034253 | Molecular mechanisms of iAs-mediated carcinogenesis through the lens of histone H2B variants | 000 | 4 | NIH | 3/4/2025 | $655,853 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F99CA284282 | Impact of neurofibromin on ER-alpha and nuclear speck post-transcriptional gene regulation | 000 | 2 | NIH | 12/9/2024 | $3,000 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01NS120489 | LRRK2 Enzymatic Mechanisms of Neurodegeneration in Parkinson's Disease | 000 | 5 | NIH | 11/13/2024 | $427,500 |
| | 2025 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35GM152184 | Molecular mechanisms of chromatin signaling and epigenetic regulation | 000 | 1 | NIH | 11/8/2024 | $0 |
| | 2025 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01NS121371 | Motor cortical circuitry adaptations in experimental Parkinson's disease | 001 | 4 | NIH | 2/25/2025 | -$1 |
| | 2025 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA269394 | Harnessing the therapeutic potential of histotripsy focused ultrasound-induced immunogenic cancer cell death | 004 | 3 | NIH | 3/18/2025 | $216,056 |
| | 2025 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA269394 | Harnessing the therapeutic potential of histotripsy focused ultrasound-induced immunogenic cancer cell death | 001 | 3 | NIH | 2/13/2025 | $320,452 |
| | 2025 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AI171984 | The roles of genetics, hormones, and gender in sexually dimorphic immune response | 000 | 3 | NIH | 3/6/2025 | -$438,099 |
| | 2025 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01HG012444 | Master regulators of unexplained variation in disease risk | 000 | 4 | NIH | 12/17/2024 | $0 |
| | 2025 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35GM131754 | Structural mechanism of DNA replication | 000 | 6 | NIH | 11/8/2024 | $0 |
| | 2025 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01NS112363 | Structural and functional studies of CALHM channels | 000 | 5 | NIH | 1/14/2025 | -$237,500 |
| | 2025 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35GM138321 | Elucidating structures and molecular mechanisms of Pannexin channels | 000 | 5 | NIH | 12/11/2024 | -$431,999 |
| | 2025 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R50CA243878 | Research Specialist Support-Targeting DNA Methylation and the Cancer Epigenome | 000 | 5 | NIH | 3/18/2025 | $0 |
| | 2025 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01NS121371 | Motor cortical circuitry adaptations in experimental Parkinson's disease | 000 | 3 | NIH | 2/25/2025 | -$41,001 |
| | 2025 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R21NS135545 | Targeted Cortical Circuit Manipulation in Parkinson's Disease | 000 | 1 | NIH | 12/11/2024 | -$240,266 |
| | 2025 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | K99NS128258 | Structural and Functional Studies on Proton-activated Chloride (PAC) Channel | 000 | 2 | NIH | 11/15/2024 | -$80,952 |
| | 2025 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F32CA260116 | Defining the regulation of UHRF1 and DNMT1 for maintenance of the epigenome | 000 | 3 | NIH | 1/23/2025 | $0 |
| | 2025 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35GM131754 | Structural mechanism of DNA replication | 001 | 5 | NIH | 2/11/2025 | $0 |
| | 2025 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01HL153219 | Structural and functional studies of the human TRPM4 and TRPM5 channels | 001 | 4 | NIH | 2/6/2025 | -$63,678 |
| | 2025 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01HL153219 | Structural and functional studies of the human TRPM4 and TRPM5 channels | 000 | 4 | NIH | 12/11/2024 | $0 |
| | 2025 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35CA209859 | Establishing and Interpreting Abnormal DNA Methylation in Cancer | 000 | 7 | NIH | 2/18/2025 | -$97,178 |
| | 2025 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35CA209859 | Establishing and Interpreting Abnormal DNA Methylation in Cancer | 001 | 8 | NIH | 2/18/2025 | $97,178 |
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| Issue Date FY: 2024 ( Subtotal = $22,595,695 ) (Continued on the next page) |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | U01CA286580 | Diet-mediated regulation of fatty acid saturation impacts cancer progression and therapy responses. | 000 | 1 | NIH | 3/25/2024 | $796,798 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | U24CA264023 | Integrative Cancer Epigenomic Data Analysis Center (ICE-DAC) | 000 | 4 | NIH | 8/7/2024 | $433,201 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R56ES034765 | Molecular mechanisms underlying metabolic reprogramming by paternal benzene exposure | 000 | 1 | NIH | 4/19/2024 | $586,660 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R50CA243878 | Research Specialist Support-Targeting DNA Methylation and the Cancer Epigenome | 000 | 6 | NIH | 7/22/2024 | $166,080 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F30GM154476 | Upstream Requirements for the Regulation of Mitochondrial Bioenergetics by the Mitochondrial Acyl Carrier Protein | 000 | 1 | NIH | 4/19/2024 | $46,694 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F30GM154476 | Upstream Requirements for the Regulation of Mitochondrial Bioenergetics by the Mitochondrial Acyl Carrier Protein | 001 | 1 | NIH | 4/19/2024 | $0 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F30GM154476 | Upstream Requirements for the Regulation of Mitochondrial Bioenergetics by the Mitochondrial Acyl Carrier Protein | 002 | 1 | NIH | 6/11/2024 | $1,280 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F99CA294248 | Determinants of susceptibility to pediatric acute myeloid leukemia | 000 | 1 | NIH | 8/29/2024 | $49,474 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | K99CA286742 | The role of AHR in modulatingimmunotherapy response and adverse events in bladder cancer | 000 | 1 | NIH | 1/23/2024 | $153,160 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01ES036051 | circSATB2, a novel regulator of arsenic-induced carcinogenesis | 000 | 1 | NIH | 1/5/2024 | $604,923 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R21AI173758 | Mechanisms of histone crosstalk with bacterial pathogens | 001 | 2 | NIH | 5/10/2024 | $23,750 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R21AI173758 | Mechanisms of histone crosstalk with bacterial pathogens | 000 | 2 | NIH | 10/30/2023 | $213,750 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA255506 | Discovery of small molecules targeting the histone acetylation reader ENL | 001 | 4 | NIH | 4/16/2024 | $21,520 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA255506 | Discovery of small molecules targeting the histone acetylation reader ENL | 000 | 4 | NIH | 11/13/2023 | $387,352 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AR084693 | Sexually dimorphic regulation of bone mass by the X-linked histone modifier KDM5C | 001 | 1 | NIH | 8/28/2024 | $6,799 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AR084693 | Sexually dimorphic regulation of bone mass by the X-linked histone modifier KDM5C | 000 | 1 | NIH | 8/15/2024 | $645,930 |
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