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 | Issue Date FY: 2025 ( Subtotal = $23,826,700 ) (Continued on the next page) |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AR079174 | 5-methylcytosine oxidation in development and disease | 000 | 5 | NIH | 6/4/2025 | $405,460 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | K99CA293261 | Targeting PTGIR-Prostacyclin Signaling to Overcome T Cell Exhaustion and Enhance Anti-Tumor Immunity | 000 | 1 | NIH | 7/30/2025 | $112,234 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AI188367 | Metabolic targeting of CD4 T cells in CNS autoimmunity | 000 | 1 | NIH | 7/8/2025 | $790,222 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | U01CA297713 | Dietary regulation of anti-tumor immunity through caloric restriction | 000 | 1 | NIH | 3/17/2025 | $767,324 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R21HD114905 | Fatty acid metabolism in disease models of mitochondrial fatty acid synthesis deficiency. | 001 | 1 | NIH | 8/4/2025 | $0 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R21HD114905 | Fatty acid metabolism in disease models of mitochondrial fatty acid synthesis deficiency. | 000 | 1 | NIH | 8/4/2025 | $288,000 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35GM160317 | Revealing the Molecular Basis of Microtubule-Intermediate Filament Interactions. | 000 | 1 | NIH | 8/9/2025 | $528,000 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AR085095 | Mitochondrial Oxidative Metabolism is a critical determinant of Muscle Satellite Cell fate & function | 000 | 1 | NIH | 8/12/2025 | $1,622,775 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F99CA305570 | Targeting mechanisms of chromatin plasticity to improve the efficacy of epigenetic solid tumor therapy | 000 | 1 | NIH | 7/29/2025 | $50,038 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35CA209859 | Establishing and Interpreting Abnormal DNA Methylation in Cancer | 002 | 10 | NIH | 6/10/2025 | $1,022,083 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01ES034253 | Molecular mechanisms of iAs-mediated carcinogenesis through the lens of histone H2B variants | 000 | 4 | NIH | 3/4/2025 | $655,853 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F30GM154476 | Upstream Requirements for the Regulation of Mitochondrial Bioenergetics by the Mitochondrial Acyl Carrier Protein | 001 | 2 | NIH | 5/22/2025 | $564 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F30GM154476 | Upstream Requirements for the Regulation of Mitochondrial Bioenergetics by the Mitochondrial Acyl Carrier Protein | 000 | 2 | NIH | 5/14/2025 | $47,974 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F99CA294248 | Determinants of susceptibility to pediatric acute myeloid leukemia | 001 | 2 | NIH | 8/15/2025 | $51,538 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F99CA294248 | Determinants of susceptibility to pediatric acute myeloid leukemia | 000 | 1 | NIH | 12/6/2024 | $3,000 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | U01CA286580 | Diet-mediated regulation of fatty acid saturation impacts cancer progression and therapy responses. | 001 | 2 | NIH | 5/28/2025 | $79,679 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | U01CA286580 | Diet-mediated regulation of fatty acid saturation impacts cancer progression and therapy responses. | 000 | 2 | NIH | 3/26/2025 | $717,119 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35GM152184 | Molecular mechanisms of chromatin signaling and epigenetic regulation | 001 | 2 | NIH | 5/2/2025 | $518,400 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01ES036051 | circSATB2, a novel regulator of arsenic-induced carcinogenesis | 000 | 2 | NIH | 11/5/2024 | $628,913 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AI165580 | Elucidating the Structural Mechanisms of NAIP Receptors in Bacterial Detection and Inflammasome Activation | 003 | 4 | NIH | 3/26/2025 | $153,195 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AI165580 | Elucidating the Structural Mechanisms of NAIP Receptors in Bacterial Detection and Inflammasome Activation | 001 | 4 | NIH | 11/5/2024 | $465,600 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R25HG011020 | Epigenomics Workshop for Graduate Students | 000 | 4 | NIH | 11/6/2024 | $51,777 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F31AG084199 | Identifying Determinants of Tau Pathology Seeding | 000 | 2 | NIH | 6/25/2025 | $48,538 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35GM152081 | Mechanisms and Applications of RNA-mediated Enzymes in Translation and Immunity | 003 | 3 | NIH | 8/5/2025 | $62,573 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35GM152081 | Mechanisms and Applications of RNA-mediated Enzymes in Translation and Immunity | 000 | 3 | NIH | 1/17/2025 | $563,163 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AG084743 | Accelerated DNA Methylation Alterations in Hutchinson-Gilford Progeria Syndrome | 001 | 3 | NIH | 6/20/2025 | $62,896 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AG084743 | Accelerated DNA Methylation Alterations in Hutchinson-Gilford Progeria Syndrome | 000 | 3 | NIH | 4/30/2025 | $707,577 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA268440 | High Throughput Screen for Inhibitors of the YEATS2 Histone Acylation Reader | 001 | 4 | NIH | 6/3/2025 | $43,462 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA268440 | High Throughput Screen for Inhibitors of the YEATS2 Histone Acylation Reader | 000 | 4 | NIH | 12/13/2024 | $391,163 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01DK139630 | Understanding putative beta-cell subtypes | 000 | 2 | NIH | 8/18/2025 | $675,646 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AG083568 | Endogenous retrovirus in joint aging and osteoarthritis development | 001 | 3 | NIH | 6/20/2025 | $46,822 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AG083568 | Endogenous retrovirus in joint aging and osteoarthritis development | 000 | 3 | NIH | 4/18/2025 | $526,751 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35GM147261 | Epigenetic Mechanisms of Retrotransposon Silencing | 000 | 4 | NIH | 7/7/2025 | $475,000 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AG077573 | Network and cellular vulnerability to pathological protein progression | 001 | 4 | NIH | 6/10/2025 | $35,292 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AG077573 | Network and cellular vulnerability to pathological protein progression | 000 | 4 | NIH | 5/9/2025 | $397,041 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AI165722 | Ketone Body Metabolism in CD8+ T Cell Responses | 001 | 4 | NIH | 6/4/2025 | $1,301,502 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01DK132216 | A Trim28-ERV axis drives phenotypic variation in obesity | 000 | 3 | NIH | 8/19/2025 | $600,000 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35GM151245 | Regulation of mitochondrial fatty acid synthesis in the control of mitochondrial metabolism. | 000 | 3 | NIH | 3/26/2025 | $427,500 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F99CA284282 | Impact of neurofibromin on ER-alpha and nuclear speck post-transcriptional gene regulation | 002 | 2 | NIH | 6/27/2025 | $0 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F99CA284282 | Impact of neurofibromin on ER-alpha and nuclear speck post-transcriptional gene regulation | 000 | 2 | NIH | 12/9/2024 | $3,000 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F30CA268840 | A Molecular Case Series: Deep Cellular and Spatial Epigenetic Characterization of Human Colorectal Cancer | 000 | 3 | NIH | 7/10/2025 | $48,538 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | T32CA251066 | Cancer Epigenetics Training (CET) Program | 000 | 5 | NIH | 7/18/2025 | $494,901 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01HG012444 | Master regulators of unexplained variation in disease risk | 001 | 5 | NIH | 7/31/2025 | $1,928,796 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01GM143308 | A NOVEL PROCESS SAFEGUARDS GENOME INTEGRITY IN THE MAMMALIAN GERM LINE | 000 | 4 | NIH | 5/29/2025 | $519,036 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35GM142779 | Understanding WNT9A/FZD9 Trafficking and Signaling | 000 | 5 | NIH | 8/11/2025 | $475,000 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F31NS139616 | Cortical Neuronal Vulnerability in Parkinson's Disease | 000 | 1 | NIH | 5/15/2025 | $47,974 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F31NS139616 | Cortical Neuronal Vulnerability in Parkinson's Disease | 001 | 1 | NIH | 5/15/2025 | $0 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01NS120489 | LRRK2 Enzymatic Mechanisms of Neurodegeneration in Parkinson's Disease | 000 | 5 | NIH | 11/13/2024 | $427,500 |
| | 2025 | 2025 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R61NS138813 | A novel gene therapy approach to reduce neurotoxicity in Parkinson's disease | 000 | 1 | NIH | 7/7/2025 | $1,009,212 |
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