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 | Issue Date FY: 2024 ( Subtotal = $6,852,023 ) |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01NS112363 | Structural and functional studies of CALHM channels | 000 | 5 | NIH | 2/15/2024 | $425,985 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | K99CA286742 | The role of AHR in modulatingimmunotherapy response and adverse events in bladder cancer | 000 | 1 | NIH | 1/23/2024 | $153,160 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R56ES034765 | Molecular mechanisms underlying metabolic reprogramming by paternal benzene exposure | 000 | 1 | NIH | 4/19/2024 | $586,660 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | U01CA286580 | Diet-mediated regulation of fatty acid saturation impacts cancer progression and therapy responses. | 000 | 1 | NIH | 3/25/2024 | $796,798 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | K22CA272912 | Oncoprotein-regulated lineage plasticity in acute leukemia | 000 | 1 | NIH | 4/18/2024 | $192,240 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F30GM154476 | Upstream Requirements for the Regulation of Mitochondrial Bioenergetics by the Mitochondrial Acyl Carrier Protein | 000 | 1 | NIH | 4/19/2024 | $46,694 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R35GM151245 | Regulation of mitochondrial fatty acid synthesis in the control of mitochondrial metabolism. | 000 | 2 | NIH | 3/22/2024 | $427,500 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AG083568 | Endogenous retrovirus in joint aging and osteoarthritis development | 000 | 2 | NIH | 4/19/2024 | $610,479 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R21AI173758 | Mechanisms of histone crosstalk with bacterial pathogens | 000 | 2 | NIH | 10/30/2023 | $213,750 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA276031 | Mechanisms of cancer mutations | 001 | 2 | NIH | 4/17/2024 | $24,127 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA276031 | Mechanisms of cancer mutations | 000 | 2 | NIH | 11/3/2023 | $434,294 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01ES034253 | Molecular mechanisms of iAs-mediated carcinogenesis through the lens of histone H2B variants | 000 | 3 | NIH | 2/21/2024 | $678,587 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA268440 | High Throughput Screen for Inhibitors of the YEATS2 Histone Acylation Reader | 001 | 3 | NIH | 4/17/2024 | $21,732 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA268440 | High Throughput Screen for Inhibitors of the YEATS2 Histone Acylation Reader | 000 | 3 | NIH | 12/26/2023 | $391,163 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AR079174 | 5-methylcytosine oxidation in development and disease | 000 | 4 | NIH | 3/27/2024 | $376,200 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01NS121371 | Motor cortical circuitry adaptations in experimental Parkinson's disease | 000 | 4 | NIH | 1/10/2024 | $427,500 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA255506 | Discovery of small molecules targeting the histone acetylation reader ENL | 001 | 4 | NIH | 4/16/2024 | $21,520 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA255506 | Discovery of small molecules targeting the histone acetylation reader ENL | 000 | 4 | NIH | 11/13/2023 | $387,352 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R25HG011020 | Epigenomics Workshop for Graduate Students | 000 | 3 | NIH | 12/4/2023 | $51,777 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AG066764 | Progressive DNA Hypomethylation as a Measure of Mitotic History and Potential Contributor to Replicative Senescence. | 000 | 5 | NIH | 4/17/2024 | $597,032 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01NS120489 | LRRK2 Enzymatic Mechanisms of Neurodegeneration in Parkinson's Disease | 000 | 4 | NIH | 11/14/2023 | $427,500 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01ES031846 | Molecular Underpinnings in the Establishment of an Oncogenic 3D Genome inResponse to Environmental Arsenic Exposure | 000 | 5 | NIH | 3/1/2024 | $565,039 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01ES036051 | circSATB2, a novel regulator of arsenic-induced carcinogenesis | 000 | 1 | NIH | 1/5/2024 | $604,923 |
| | 2024 | 2024 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01NS113894 | Epigenetic contributions to symptom asymmetry in Parkinson's disease | 000 | 5 | NIH | 4/5/2024 | $433,105 |
| | 2024 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F31CA257440 | Mechanisms of DNMT3B-mediated DNA Methylation Maintenance | 000 | 3 | NIH | 12/12/2023 | -$25,595 |
| | 2024 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AG067426 | Alzheimer's disease genetic architecture in the Portuguese population | 001 | 4 | NIH | 12/29/2023 | -$908,823 |
| | 2024 | 2022 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R33NS106078 | Combining synucleinopathy and mitochondrial deficits in a novel mouse model of Parkinsons disease | 000 | 3 | NIH | 2/21/2024 | -$39,099 |
| | 2024 | 2022 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AG067426 | Alzheimer's disease genetic architecture in the Portuguese population | 000 | 3 | NIH | 12/29/2023 | -$273,670 |
| | 2024 | 2022 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AI070285 | Structural biology of proteostasis in M. tuberculosis | 000 | 16 | NIH | 2/27/2024 | $0 |
| | 2024 | 2021 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R21HG011964 | Epigenetic control and probabilistic disease programming | 000 | 1 | NIH | 2/28/2024 | $0 |
| | 2024 | 2021 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R56AG070857 | Role of the endolysosomal pathway in Lewy body dementia - from population genomics to single cells | 000 | 1 | NIH | 2/8/2024 | -$665,133 |
| | 2024 | 2021 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R21NS122376 | Role of T cells in alpha-synuclein pathology | 000 | 1 | NIH | 2/12/2024 | -$32,608 |
| | 2024 | 2021 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R00HL133458 | The Role of Wnt Signaling in Normal and Abnormal Hematopoiesis | 000 | 5 | NIH | 2/15/2024 | -$96,992 |
| | 2024 | 2021 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01NS105432 | Mechanisms of VPS35-Dependent Neurodegeneration in Parkinson's Disease | 000 | 5 | NIH | 3/6/2024 | $0 |
| | 2024 | 2021 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | U01CA152653 | Detection and prognosis of early-stage pancreatic cancer by interdependent plasma markers | 000 | 10 | NIH | 1/8/2024 | -$1,174 |
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| Issue Date FY: 2023 ( Subtotal = $29,288,802 ) (Continued on the next page) |
| | 2023 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R50CA243878 | Research Specialist Support-Targeting DNA Methylation and the Cancer Epigenome | 001 | 5 | NIH | 8/23/2023 | $87,121 |
| | 2023 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01NS121371 | Motor cortical circuitry adaptations in experimental Parkinson's disease | 001 | 3 | NIH | 2/6/2023 | $466,201 |
| | 2023 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R21AI173758 | Mechanisms of histone crosstalk with bacterial pathogens | 000 | 1 | NIH | 11/18/2022 | $285,000 |
| | 2023 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01CA231466 | Molecular mechanisms of protein glycosylation and trafficking | 001 | 6 | NIH | 3/1/2023 | $475,000 |
| | 2023 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F32CA260116 | Defining the regulation of UHRF1 and DNMT1 for maintenance of the epigenome | 000 | 3 | NIH | 2/23/2023 | $71,792 |
| | 2023 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AG066764 | Progressive DNA Hypomethylation as a Measure of Mitotic History and Potential Contributor to Replicative Senescence. | 001 | 4 | NIH | 4/19/2023 | $597,032 |
| | 2023 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AG083568 | Endogenous retrovirus in joint aging and osteoarthritis development | 000 | 1 | NIH | 8/4/2023 | $607,781 |
| | 2023 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01AG084743 | Accelerated DNA Methylation Alterations in Hutchinson-Gilford Progeria Syndrome | 000 | 1 | NIH | 9/21/2023 | $786,197 |
| | 2023 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | DP2DK139569 | IDENTIFYING MICROBIAL MECHANISMS THAT REGULATE ANIMAL INSULIN SIGNALING | 000 | 1 | NIH | 9/15/2023 | $1,710,000 |
| | 2023 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R21NS135545 | Targeted Cortical Circuit Manipulation in Parkinson's Disease | 000 | 1 | NIH | 9/15/2023 | $485,188 |
| | 2023 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R25HG011020 | Epigenomics Workshop for Graduate Students | 000 | 2 | NIH | 12/2/2022 | $51,777 |
| | 2023 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | R01DK132216 | A Trim28-ERV axis drives phenotypic variation in obesity | 000 | 1 | NIH | 8/17/2023 | $600,000 |
| | 2023 | 2023 | VAN ANDEL RESEARCH INSTITUTE | 333 BOSTWICK AVE NE | GRAND RAPIDS | MI | 49503-2518 | KENT | USA | F99CA284282 | Impact of neurofibromin on ER-alpha and nuclear speck post-transcriptional gene regulation | 000 | 1 | NIH | 8/15/2023 | $48,194 |
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