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 | Issue Date FY: 2023 ( Subtotal = $40,364,957 ) (Continued on the next page) |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R25HL121037 | Promoting Underrepresented Minority Advancement in the Sciences (PUMAS) | 000 | 10 | NIH | 5/24/2023 | $66,240 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K99HD110319 | Effects of PrEP Drugs on Female Genital HIV Infection and Women's Reproductive Health | 001 | 2 | NIH | 9/13/2023 | $126,630 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG065540 | Study the Protective Roles of ApoE2 in Alzheimer's Disease Using Reprogrammed Isogenic Cells | 000 | 4 | NIH | 4/26/2023 | $724,286 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K02NS110973 | Fibrinogen-mediated mechanisms of preterm infant brain injury | 000 | 4 | NIH | 1/5/2023 | $150,059 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01CA276368 | Decoding and reprogramming T cells through synthetic biology for cancer immunotherapy | 000 | 1 | NIH | 12/16/2022 | $771,499 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG064579 | Cell and Network Disruptions and Associated Pathogenenesis in Tauopathy and Down Syndrome | 000 | 4 | NIH | 3/24/2023 | $641,436 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R35NS097976 | Neurovascular Interactions: Mechanisms, imaging, therapeutic potential | 000 | 8 | NIH | 7/26/2023 | $1,415,966 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG081085 | Cellular perturbations to enhance precise therapeutic genome editing to treat FTD/ALS | 001 | 1 | NIH | 3/29/2023 | $0 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | UM1AI164559 | HOPE - HIV Obstruction by Programmed Epigenetics | 001 | 3 | NIH | 7/5/2023 | $998,243 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01MH123178 | Resolving single-cell brain regulatory elements with bulk data supervised models | 000 | 4 | NIH | 3/17/2023 | $606,575 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG061150 | Apolipoprotein E4-related Electrophysiological and Metabolic Impairments in Aging and Alzheimer's Disease | 000 | 5 | NIH | 1/4/2023 | $655,674 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG081085 | Cellular perturbations to enhance precise therapeutic genome editing to treat FTD/ALS | 000 | 1 | NIH | 3/29/2023 | $69,080 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | UM1AI164559 | HOPE - HIV Obstruction by Programmed Epigenetics | 000 | 3 | NIH | 4/20/2023 | $5,336,026 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP1DA051144 | A Gene Drive Therapy for HIV: single-administration intervention for high-risk groups | 001 | 4 | NIH | 8/30/2023 | $187,110 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01DK131526 | Multiomics characterization, induction, and elimination of the HIV gut reservoir | 000 | 2 | NIH | 5/25/2023 | $725,170 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG071697 | Neuronal ApoE Drives Selective Neurodegeneration in Alzheimer's Disease | 000 | 3 | NIH | 5/25/2023 | $817,317 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP1DA051144 | A Gene Drive Therapy for HIV: single-administration intervention for high-risk groups | 000 | 4 | NIH | 3/17/2023 | $945,000 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG078164 | Develop AD Connectivity Maps with Human iPSC-Derived Brain Cells and their Use | 000 | 2 | NIH | 6/1/2023 | $941,764 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | P01AG073082 | Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease | 001 | 3 | NIH | 8/3/2023 | $65,507 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01DK123746 | Modeling intestinal dysfunction in HIV infection with organoid technology | 000 | 4 | NIH | 1/9/2023 | $789,764 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL057181 | Cardiogenesis: Molecular Mechanisms | 000 | 28 | NIH | 8/25/2023 | $803,250 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD036170 | Transfer learning leveraging large-scale transcriptomics to map disrupted gene networks in cardiovascular disease | 000 | 1 | NIH | 9/22/2023 | $472,499 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R21AI172060 | Characterizing ART-free NK cell-mediated control of HIV infection in people living with HIV | 000 | 2 | NIH | 7/18/2023 | $236,250 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL160862 | Linking microbiome genetic variants with cardiovascular phenotypes in 50,000 individuals | 000 | 2 | NIH | 6/16/2023 | $685,007 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | P01AG073082 | Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease | 000 | 3 | NIH | 8/2/2023 | $4,657,222 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL150100 | Aortic Valve Disease: Mechanisms and Therapeutic Approaches | 001 | 4 | NIH | 3/10/2023 | $67,911 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL150100 | Aortic Valve Disease: Mechanisms and Therapeutic Approaches | 000 | 4 | NIH | 1/6/2023 | $611,213 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD036170 | Transfer learning leveraging large-scale transcriptomics to map disrupted gene networks in cardiovascular disease | 000 | 1 | NIH | 9/22/2023 | $1 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K01AG078485 | Metabolic Vulnerability and Effects of APOE in Human Neurons with Impaired Endocytic Recycling | 000 | 2 | NIH | 4/13/2023 | $130,950 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | P01HL146366 | Combinatorial Regulation of Gene Networks During Cardiac Development and Disease | 000 | 5 | NIH | 8/25/2023 | $2,723,920 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R21AG085079 | Transcriptomic and Proteomic Analysis of Tau-dependent E/I Imbalance | 000 | 1 | NIH | 9/15/2023 | $519,750 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R21AG085079 | Transcriptomic and Proteomic Analysis of Tau-dependent E/I Imbalance | 001 | 1 | NIH | 9/19/2023 | $0 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01LM013617 | Image Tools for Computational Cellular Barcoding and Automated Annotation | 000 | 2 | NIH | 12/9/2022 | $405,469 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R21EB031393 | RetroDecoys: Temporally-regulated and cell type selective technology for transcriptional control | 001 | 2 | NIH | 1/31/2023 | $28,350 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI109593 | Modulating Stochastic Gene Expression for Cell-fate Control and Therapeutics | 000 | 8 | NIH | 2/17/2023 | $918,446 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01DA049525 | Exploring HIV-associated Neurocognitive Disorder (HAND) and HIV Latency at the Single Cell Level in Cerebral Organoids | 001 | 5 | NIH | 8/17/2023 | $708,000 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01DA059551 | Sorting and Sequencing Latent Reservoirs in HIV+ Opioid Users | 000 | 1 | NIH | 9/15/2023 | $1,630,854 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R21EB031393 | RetroDecoys: Temporally-regulated and cell type selective technology for transcriptional control | 000 | 2 | NIH | 12/22/2022 | $255,150 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R33DA048444 | Single-Cell Transcriptomics of Non-Activated Latently Infected T cells Isolated from HIV+ Drug Users | 000 | 5 | NIH | 6/21/2023 | $941,806 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K00CA245718 | Expanding the scope of protein degradation and stability using chemoproteomic platforms | 000 | 5 | NIH | 3/28/2023 | $94,589 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | RF1AG083079 | Roles of TREM2 and TYROBP in AD-related Network Hyperexcitability | 000 | 1 | NIH | 8/18/2023 | $2,833,089 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS121287 | Role of Myeloid And CD4+ T Immune Cells in Post-Traumatic Plasticity | 001 | 2 | NIH | 1/31/2023 | $41,240 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS121287 | Role of Myeloid And CD4+ T Immune Cells in Post-Traumatic Plasticity | 000 | 2 | NIH | 12/1/2022 | $371,162 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL155906 | Gene regulatory networks for heart development | 001 | 3 | NIH | 3/3/2023 | $60,010 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K01AG083732 | Machine Learning Approaches for Behavioral Phenotyping of Humanized Knock-in Models of Alzheimer's Disease | 000 | 1 | NIH | 8/2/2023 | $150,630 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K99NS126707 | Epigenomic regulation of oxidative stress-producing innate immunity in neuroinflammation | 000 | 2 | NIH | 4/3/2023 | $120,864 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL155906 | Gene regulatory networks for heart development | 000 | 3 | NIH | 1/13/2023 | $540,091 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI083139 | Role of Factor Acetylation in the Regulation of HIV Transcription | 000 | 14 | NIH | 6/22/2023 | $621,854 |
| | 2023 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL163268 | Small molecule therapeutic for calcific aortic valve disease | 000 | 1 | NIH | 8/1/2023 | $798,104 |
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