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 | Issue Date FY: 2026 ( Subtotal = $44,752,099 ) (Continued on the next page) |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K01HL173644 | Addressing Disparities in Polygenic Risk Score for Coronary Heart Diseases in Diverse Populations | 001 | 3 | NIH | 8/26/2026 | $179,280 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01DK131526 | Multiomics characterization, induction, and elimination of the HIV gut reservoir | 000 | 5 | NIH | 5/5/2026 | $758,183 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD036170 | Transfer learning leveraging large-scale transcriptomics to map disrupted gene networks in cardiovascular disease | 001 | 4 | NIH | 8/28/2026 | $944,999 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD036170 | Transfer learning leveraging large-scale transcriptomics to map disrupted gene networks in cardiovascular disease | 001 | 4 | NIH | 8/28/2026 | $1 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01CA276368 | Decoding and reprogramming T cells through synthetic biology for cancer immunotherapy | 001 | 4 | NIH | 4/16/2026 | $74,919 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01CA276368 | Decoding and reprogramming T cells through synthetic biology for cancer immunotherapy | 000 | 4 | NIH | 12/22/2025 | $674,268 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG088324 | Proteostasis, Neuroinflammation and Neurodegeneration in Frontotemporal Dementia | 000 | 2 | NIH | 3/25/2026 | $607,816 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01DA063159 | Targeted small molecule recruitment to suppress the HIV transcriptionally active reservoir | 000 | 2 | NIH | 3/27/2026 | $655,855 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG092390 | Targeting Nell2 and GABAergic Dysfunction to Mitigate APOE4-Driven Pathogenesis in Alzheimer's Disease | 000 | 2 | NIH | 3/25/2026 | $778,757 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG078164 | Develop AD Connectivity Maps with Human iPSC-Derived Brain Cells and their Use | 000 | 5 | NIH | 6/1/2026 | $943,826 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R25HL121037 | PUMAS - A Pipeline program for comMUnity college students Advancing in the Sciences | 000 | 13 | NIH | 4/8/2026 | $166,320 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL114948 | Early cardiac progenitors | 001 | 14 | NIH | 7/7/2026 | $718,069 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01ES036325 | Investigating Novel Genetic Variants that Confer Susceptibility to Pesticide-induced Parkinson's Disease | 000 | 2 | NIH | 1/1/2026 | $706,158 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG087323 | Exploring NOX2-Mediated Network Impairment and Neurodegeneration in Alzheimer's Disease | 001 | 2 | NIH | 2/25/2026 | $84,217 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG087323 | Exploring NOX2-Mediated Network Impairment and Neurodegeneration in Alzheimer's Disease | 000 | 2 | NIH | 12/16/2025 | $757,958 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL163268 | Small molecule therapeutic for calcific aortic valve disease | 000 | 4 | NIH | 5/13/2026 | $782,141 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG085468 | Study Alzheimer's Disease Protective APOE Variants | 001 | 3 | NIH | 2/23/2026 | $94,136 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG085468 | Study Alzheimer's Disease Protective APOE Variants | 000 | 3 | NIH | 1/8/2026 | $847,228 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AI183286 | Targeting the transcriptionally-active reservoir to reduce chronic inflammation in aged people with HIV | 000 | 3 | NIH | 2/18/2026 | $890,051 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | P01AI195327 | PhAIge Therapy Center: AI-Guided Tailspike Engineering and Molecular Typing for Rapid Phage Design and Testing Against ESKAPE Pathogens | 000 | 1 | NIH | 5/12/2026 | $2,047,959 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL181372 | Chromatin Regulation of Immune Cells in Myocardial Inflammation | 000 | 2 | NIH | 7/31/2026 | $765,888 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R03DE036186 | Defining Molecular Interactions Between Commensal Respiratory Viruses and the Human Host | 000 | 1 | NIH | 9/1/2026 | $1 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R03DE036186 | Defining Molecular Interactions Between Commensal Respiratory Viruses and the Human Host | 000 | 1 | NIH | 9/1/2026 | $377,999 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG094162 | Cell type-specific peripheral immune response as a biomarker and therapeutic target for Alzheimer's disease | 000 | 1 | NIH | 9/4/2026 | $79,348 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K99HL188571 | Linking microbes to cardiovascular-associated metabolites using knowledge-based machine learning | 000 | 1 | NIH | 9/4/2026 | $134,439 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG093119 | Functionalization of rare noncoding variants as drivers of Alzheimer's disease risk | 000 | 1 | NIH | 9/9/2026 | $845,617 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL175312 | Epigenomic mechanisms of cardiac fibrosis and heart failure | 000 | 2 | NIH | 7/31/2026 | $773,842 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R21AG101017 | Mechanistic Exploration of TREM2 Antibodies that Can Suppress Alzheimer's Disease Related Network Hyperexcitability and Cognitive Deficits | 000 | 1 | NIH | 9/1/2026 | $519,750 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | S15OD042572 | Roche Discovery Ultra | 000 | 1 | NIH | 8/18/2026 | $175,000 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL187295 | Machine learning discovery of variants that alter gene regulation in cardiovascular development and disease | 000 | 1 | NIH | 8/5/2026 | $925,796 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG097607 | Genetic dissection of the 17q21.31 MAPT locus in neurodegenerative disease | 001 | 1 | NIH | 8/18/2026 | $150,529 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG097607 | Genetic dissection of the 17q21.31 MAPT locus in neurodegenerative disease | 000 | 1 | NIH | 2/6/2026 | $790,288 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG093939 | Understanding ApoE4-induced metabolic shifts in Alzheimer's disease | 001 | 1 | NIH | 5/25/2026 | $0 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG093939 | Understanding ApoE4-induced metabolic shifts in Alzheimer's disease | 000 | 1 | NIH | 2/6/2026 | $801,193 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R21CA318067 | Engineering Targeted Delivery Vehicles for Genome Editing in Hematopoietic Stem Cells | 000 | 1 | NIH | 7/10/2026 | $485,966 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AI189605 | Transcriptional and post-transcriptional regulation of human Treg identity and function | 000 | 1 | NIH | 2/6/2026 | $3,601,712 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG083079 | Roles of TREM2 and TYROBP in AD-related Network Hyperexcitability | 000 | 2 | NIH | 6/25/2026 | $944,363 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K99HL188356 | Dissecting the Chromatin and Spatial Mechanisms of HMGN1-MediatedCongenital heart defects in Down syndrome | 000 | 1 | NIH | 7/22/2026 | $131,307 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K99NS146256 | Microglial control of thalamocortical circuits in Alzheimer's disease | 000 | 1 | NIH | 2/5/2026 | $122,850 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AI203534 | UNDO-HIV: UNDerstanding and Obliterating the active HIV reservoir | 000 | 1 | NIH | 7/14/2026 | $896,029 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS124848 | Dissecting the Etiology of The Lewy Body Dementias | 000 | 3 | NIH | 6/5/2026 | $822,417 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL179702 | Mechanisms of Oxygen Toxicity | 000 | 2 | NIH | 6/23/2026 | $717,190 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R33NS133257 | OPC-X screen: Discovery of small molecule inhibitors to overcome extrinsic inhibition of remyelination. | 001 | 3 | NIH | 7/23/2026 | $472,500 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R61DA065570 | Studying NeuroHIV and addictive substances in a human microglia-neuron chimera mouse model | 000 | 2 | NIH | 8/31/2026 | $1,140,888 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS142087 | Understanding and Treating NAXD Deficiency Using Vitamin B3-Based Approaches | 000 | 2 | NIH | 5/20/2026 | $574,921 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37CA295736 | A spatial profiling-based immune hub perturbation platform to improve immunotherapy in colon cancer | 000 | 2 | NIH | 6/3/2026 | $661,005 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG092732 | Mitochondrial DNA Compaction and the Accumulation of Mutations with Age and Stress | 000 | 2 | NIH | 4/9/2026 | $793,777 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL057181 | Cardiogenesis: Molecular Mechanisms | 000 | 31 | NIH | 7/24/2026 | $787,185 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI083139 | Role of Factor Acetylation in the Regulation of HIV Transcription | 000 | 17 | NIH | 6/22/2026 | $737,100 |
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