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 | Issue Date FY: 2025 ( Subtotal = $14,344,115 ) (Continued on the next page) |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32HD114427 | Transcriptional variation in human milk | 001 | 2 | NIH | 6/6/2025 | $1,236 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS121287 | Role of Myeloid And CD4+ T Immune Cells in Post-Traumatic Plasticity | 000 | 4 | NIH | 11/21/2024 | $371,162 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R21HL173710 | Targeted Delivery of Cas9 to Lung Epithelial Cells using Enveloped Delivery Vehicles | 000 | 2 | NIH | 3/31/2025 | $283,500 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG072052 | C9orf72 frontotemporal dementia (FTD) and amyotrophic lateral sclerosis(ALS): using patient cells and CRISPR to reveal therapeutic approaches | 001 | 3 | NIH | 6/10/2025 | $56,699 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG072052 | C9orf72 frontotemporal dementia (FTD) and amyotrophic lateral sclerosis(ALS): using patient cells and CRISPR to reveal therapeutic approaches | 000 | 3 | NIH | 4/1/2025 | $637,876 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG085961 | Investigation into transcriptomic control of dentate granule cell maturation and hyperexcitability in the apoE4 Alzheimer's Disease model | 001 | 2 | NIH | 5/29/2025 | $0 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG085961 | Investigation into transcriptomic control of dentate granule cell maturation and hyperexcitability in the apoE4 Alzheimer's Disease model | 000 | 2 | NIH | 11/19/2024 | $76,756 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG092683 | Harnessing novel machine learning approaches for behavioral segmentation and brain signal integration in humanized models of Alzheimer's disease | 000 | 1 | NIH | 6/11/2025 | $817,357 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K01AG083732 | Machine Learning Approaches for Behavioral Phenotyping of Humanized Knock-in Models of Alzheimer's Disease | 000 | 3 | NIH | 5/16/2025 | $150,630 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01DK131526 | Multiomics characterization, induction, and elimination of the HIV gut reservoir | 000 | 4 | NIH | 4/29/2025 | $724,238 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG082460 | Understanding how neuronal glucose metabolism changes in AD due to ApoE4 | 001 | 3 | NIH | 6/23/2025 | $1,428 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG082460 | Understanding how neuronal glucose metabolism changes in AD due to ApoE4 | 000 | 3 | NIH | 4/18/2025 | $83,932 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG088324 | Proteostasis, Neuroinflammation and Neurodegeneration in Frontotemporal Dementia | 000 | 1 | NIH | 5/16/2025 | $630,496 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01CA276368 | Decoding and reprogramming T cells through synthetic biology for cancer immunotherapy | 001 | 3 | NIH | 6/6/2025 | $74,919 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01CA276368 | Decoding and reprogramming T cells through synthetic biology for cancer immunotherapy | 000 | 3 | NIH | 1/13/2025 | $674,268 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG092390 | Targeting Nell2 and GABAergic Dysfunction to Mitigate APOE4-Driven Pathogenesis in Alzheimer's Disease | 000 | 1 | NIH | 5/16/2025 | $804,450 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01DA063159 | Targeted small molecule recruitment to suppress the HIV transcriptionally active reservoir | 000 | 1 | NIH | 5/7/2025 | $687,416 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG078164 | Develop AD Connectivity Maps with Human iPSC-Derived Brain Cells and their Use | 000 | 4 | NIH | 5/22/2025 | $922,930 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R13NS143282 | American Society for Neural Therapy and Repair Annual Conference April 2025 | 000 | 1 | NIH | 4/25/2025 | $10,000 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R13NS143282 | American Society for Neural Therapy and Repair Annual Conference April 2025 | 001 | 1 | NIH | 5/30/2025 | $10,000 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R13NS143282 | American Society for Neural Therapy and Repair Annual Conference April 2025 | 001 | 1 | NIH | 5/30/2025 | -$10,000 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01ES036325 | Investigating Novel Genetic Variants that Confer Susceptibility to Pesticide-induced Parkinson's Disease | 000 | 1 | NIH | 1/17/2025 | $728,408 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01LM013617 | Image Tools for Computational Cellular Barcoding and Automated Annotation | 001 | 4 | NIH | 6/6/2025 | $39,834 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01LM013617 | Image Tools for Computational Cellular Barcoding and Automated Annotation | 000 | 4 | NIH | 12/20/2024 | $358,515 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG087323 | Exploring NOX2-Mediated Network Impairment and Neurodegeneration in Alzheimer's Disease | 000 | 1 | NIH | 12/5/2024 | $842,175 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG071697 | Neuronal ApoE Drives Selective Neurodegeneration in Alzheimer's Disease | 000 | 5 | NIH | 5/12/2025 | $735,586 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL163268 | Small molecule therapeutic for calcific aortic valve disease | 000 | 3 | NIH | 4/25/2025 | $718,293 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AI183286 | Targeting the transcriptionally-active reservoir to reduce chronic inflammation in aged people with HIV | 000 | 2 | NIH | 4/10/2025 | $891,217 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG085468 | Study Alzheimer's Disease Protective APOE Variants | 000 | 2 | NIH | 11/21/2024 | $847,228 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG092732 | Mitochondrial DNA Compaction and the Accumulation of Mutations with Age and Stress | 000 | 1 | NIH | 6/17/2025 | $793,777 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI083139 | Role of Factor Acetylation in the Regulation of HIV Transcription | 002 | 16 | NIH | 6/23/2025 | $737,100 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL057181 | Cardiogenesis: Molecular Mechanisms | 002 | 30 | NIH | 5/27/2025 | $803,250 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS128909 | Elucidating microvascular contributions to cognitive impairment at single-cell resolution | 005 | 4 | NIH | 6/27/2025 | $1,165,270 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32HD114427 | Transcriptional variation in human milk | 000 | 2 | NIH | 12/19/2024 | $77,284 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI109593 | Modulating Stochastic Gene Expression for Cell-fate Control and Therapeutics | 003 | 9 | NIH | 3/26/2025 | -$11,230 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI109593 | Modulating Stochastic Gene Expression for Cell-fate Control and Therapeutics | 002 | 9 | NIH | 3/26/2025 | -$55,343 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI109593 | Modulating Stochastic Gene Expression for Cell-fate Control and Therapeutics | 000 | 9 | NIH | 12/4/2024 | -$447,173 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP2HG012442 | SINGLE-CELL CHEMICAL TRANSCRIPTOMIC DISSECTION OF AN ESSENTIAL TRANSCRIPTION FACTOR NETWORK | 001 | 3 | NIH | 2/24/2025 | $1 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K00CA245718 | Expanding the scope of protein degradation and stability using chemoproteomic platforms | 000 | 6 | NIH | 10/10/2024 | -$92,430 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | U01HL157989 | Genetic determinants of 4D genome folding in human cardiac development | 000 | 5 | NIH | 6/24/2025 | $0 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R25HL121037 | Promoting Underrepresented and Marginalized Populations' Advancement in the Sciences (PUMAS) | 001 | 11 | NIH | 3/27/2025 | $62,600 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP1DA051144 | A Gene Drive Therapy for HIV: Single-Administration Intervention for High-RiskGroups | 000 | 5 | NIH | 12/18/2024 | -$716,839 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP1DA051144 | A Gene Drive Therapy for HIV: Single-Administration Intervention for High-RiskGroups | 004 | 5 | NIH | 3/25/2025 | -$228,161 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32NS127998 | Deconstructing epileptic circuits in a mouse model of SLC6A1 syndrome | 000 | 2 | NIH | 4/24/2025 | -$6,096 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD033362 | Self-Assembling Spike-EBR Nanoparticles as a Vaccine Platform Technology Against SARS-CoV-2 and Future Pandemic Coronaviruses | 002 | 3 | NIH | 10/25/2024 | $1 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD033362 | Self-Assembling Spike-EBR Nanoparticles as a Vaccine Platform Technology Against SARS-CoV-2 and Future Pandemic Coronaviruses | 002 | 3 | NIH | 10/25/2024 | $466,930 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD033362 | Self-Assembling Spike-EBR Nanoparticles as a Vaccine Platform Technology Against SARS-CoV-2 and Future Pandemic Coronaviruses | 003 | 3 | NIH | 4/16/2025 | $0 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD033362 | Self-Assembling Spike-EBR Nanoparticles as a Vaccine Platform Technology Against SARS-CoV-2 and Future Pandemic Coronaviruses | 003 | 3 | NIH | 4/16/2025 | $0 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI083139 | Role of Factor Acetylation in the Regulation of HIV Transcription | 001 | 15 | NIH | 2/25/2025 | $170,458 |
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