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 | Issue Date FY: 2026 ( Subtotal = $1,803,387 ) |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01CA276368 | Decoding and reprogramming T cells through synthetic biology for cancer immunotherapy | 000 | 4 | NIH | 12/22/2025 | $674,268 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS121287 | Role of Myeloid And CD4+ T Immune Cells in Post-Traumatic Plasticity | 000 | 5 | NIH | 12/12/2025 | $371,161 |
| | 2026 | 2026 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG087323 | Exploring NOX2-Mediated Network Impairment and Neurodegeneration in Alzheimer's Disease | 000 | 2 | NIH | 12/16/2025 | $757,958 |
| | 2026 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01LM013617 | Image Tools for Computational Cellular Barcoding and Automated Annotation | 000 | 4 | NIH | 11/25/2025 | $0 |
| | 2026 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HG013736 | Methods to build and annotate tissue atlases using spatial genomic data | 000 | 2 | NIH | 12/12/2025 | $0 |
|
| Issue Date FY: 2025 ( Subtotal = $49,322,369 ) (Continued on the next page) |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL175312 | Epigenomic mechanisms of cardiac fibrosis and heart failure | 000 | 1 | NIH | 9/12/2025 | $811,885 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01DK131526 | Multiomics characterization, induction, and elimination of the HIV gut reservoir | 000 | 4 | NIH | 4/29/2025 | $724,238 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD036170 | Transfer learning leveraging large-scale transcriptomics to map disrupted gene networks in cardiovascular disease | 000 | 3 | NIH | 8/4/2025 | $1 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R61AG094667 | Enhancer-AAVs to monitor and restore cell-type selective inhibitory deficits and circuit dysfunction in humanized Alzheimer's disease models | 000 | 1 | NIH | 7/29/2025 | $1,459,072 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01ES036325 | Investigating Novel Genetic Variants that Confer Susceptibility to Pesticide-induced Parkinson's Disease | 000 | 1 | NIH | 1/17/2025 | $728,408 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG071697 | Neuronal ApoE Drives Selective Neurodegeneration in Alzheimer's Disease | 001 | 5 | NIH | 9/4/2025 | $65,386 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL163268 | Small molecule therapeutic for calcific aortic valve disease | 000 | 3 | NIH | 4/25/2025 | $718,293 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD033362 | Self-Assembling Spike-EBR Nanoparticles as a Vaccine Platform Technology Against SARS-CoV-2 and Future Pandemic Coronaviruses | 005 | 4 | NIH | 8/8/2025 | $1 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD033362 | Self-Assembling Spike-EBR Nanoparticles as a Vaccine Platform Technology Against SARS-CoV-2 and Future Pandemic Coronaviruses | 005 | 4 | NIH | 8/8/2025 | $944,999 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI083139 | Role of Factor Acetylation in the Regulation of HIV Transcription | 002 | 16 | NIH | 6/23/2025 | $737,100 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K99HL177318 | Uncovering the Mechanisms that Enable Cardiac Progenitors to Build the Linear Heart Tube | 000 | 1 | NIH | 7/9/2025 | $134,998 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AT013724 | A Revitalized Framework for Vitamin Biology: New Sensors, Pathways and Precision Therapies | 001 | 1 | NIH | 8/14/2025 | $20,000 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AT013724 | A Revitalized Framework for Vitamin Biology: New Sensors, Pathways and Precision Therapies | 001 | 1 | NIH | 8/14/2025 | -$20,000 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG092732 | Mitochondrial DNA Compaction and the Accumulation of Mutations with Age and Stress | 000 | 1 | NIH | 6/17/2025 | $793,777 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37CA295736 | A spatial profiling-based immune hub perturbation platform to improve immunotherapy in colon cancer | 000 | 1 | NIH | 7/30/2025 | $710,361 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG076647 | Study Susceptibility and Resistance to ApoE4 in Alzheimer's Disease | 000 | 2 | NIH | 7/29/2025 | $861,422 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R00HD110319 | Effects of PrEP Drugs on Female Genital HIV Infection and Women's Reproductive Health | 001 | 3 | NIH | 8/21/2025 | $747,000 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R00HD110319 | Effects of PrEP Drugs on Female Genital HIV Infection and Women's Reproductive Health | 001 | 3 | NIH | 8/21/2025 | -$747,000 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R00HD110319 | Effects of PrEP Drugs on Female Genital HIV Infection and Women's Reproductive Health | 000 | 3 | NIH | 8/7/2025 | $747,000 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R33NS133257 | OPC-X screen: Discovery of small molecule inhibitors to overcome extrinsic inhibition of remyelination. | 000 | 2 | NIH | 8/18/2025 | $472,500 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R61DA065570 | Studying NeuroHIV and addictive substances in a human microglia-neuron chimera mouse model | 000 | 1 | NIH | 8/15/2025 | $1,088,600 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R61DA065570 | Studying NeuroHIV and addictive substances in a human microglia-neuron chimera mouse model | 001 | 1 | NIH | 9/19/2025 | -$1,088,599 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R61DA065570 | Studying NeuroHIV and addictive substances in a human microglia-neuron chimera mouse model | 001 | 1 | NIH | 9/19/2025 | $1,088,599 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL179702 | Mechanisms of Oxygen Toxicity | 000 | 1 | NIH | 8/19/2025 | $731,827 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R35NS143067 | Neurovascular Interactions: Mechanisms, Imaging, Therapeutics | 000 | 1 | NIH | 8/14/2025 | $1,375,478 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS124848 | Dissecting the Etiology of The Lewy Body Dementias | 000 | 2 | NIH | 8/15/2025 | $764,836 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG082460 | Understanding how neuronal glucose metabolism changes in AD due to ApoE4 | 001 | 3 | NIH | 6/23/2025 | $1,428 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG082460 | Understanding how neuronal glucose metabolism changes in AD due to ApoE4 | 000 | 3 | NIH | 4/18/2025 | $83,932 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01CA276368 | Decoding and reprogramming T cells through synthetic biology for cancer immunotherapy | 001 | 3 | NIH | 6/6/2025 | $74,919 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01CA276368 | Decoding and reprogramming T cells through synthetic biology for cancer immunotherapy | 000 | 3 | NIH | 1/13/2025 | $674,268 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD036170 | Transfer learning leveraging large-scale transcriptomics to map disrupted gene networks in cardiovascular disease | 000 | 3 | NIH | 8/4/2025 | $472,499 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG088324 | Proteostasis, Neuroinflammation and Neurodegeneration in Frontotemporal Dementia | 000 | 1 | NIH | 5/16/2025 | $630,496 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01DA063159 | Targeted small molecule recruitment to suppress the HIV transcriptionally active reservoir | 000 | 1 | NIH | 5/7/2025 | $687,416 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG092390 | Targeting Nell2 and GABAergic Dysfunction to Mitigate APOE4-Driven Pathogenesis in Alzheimer's Disease | 000 | 1 | NIH | 5/16/2025 | $804,450 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL160862 | Linking microbiome genetic variants with cardiovascular phenotypes in 50,000 individuals | 000 | 4 | NIH | 8/7/2025 | $685,007 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL181372 | Chromatin Regulation of Immune Cells in Myocardial Inflammation | 000 | 1 | NIH | 9/12/2025 | $803,768 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG078164 | Develop AD Connectivity Maps with Human iPSC-Derived Brain Cells and their Use | 000 | 4 | NIH | 5/22/2025 | $922,930 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R13NS143282 | American Society for Neural Therapy and Repair Annual Conference April 2025 | 000 | 1 | NIH | 4/25/2025 | $10,000 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R13NS143282 | American Society for Neural Therapy and Repair Annual Conference April 2025 | 001 | 1 | NIH | 5/30/2025 | $10,000 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R13NS143282 | American Society for Neural Therapy and Repair Annual Conference April 2025 | 001 | 1 | NIH | 5/30/2025 | -$10,000 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | P01AG073082 | Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease | 001 | 5 | NIH | 8/27/2025 | $0 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | P01AG073082 | Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease | 000 | 5 | NIH | 8/5/2025 | $4,564,091 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL114948 | Early cardiac progenitors | 001 | 13 | NIH | 7/30/2025 | $777,297 |
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