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 | Issue Date FY: 2025 ( Subtotal = $2,642,618 ) |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS121287 | Role of Myeloid And CD4+ T Immune Cells in Post-Traumatic Plasticity | 000 | 4 | NIH | 11/21/2024 | $371,162 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01CA276368 | Decoding and reprogramming T cells through synthetic biology for cancer immunotherapy | 000 | 3 | NIH | 1/13/2025 | $674,268 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG087323 | Exploring NOX2-Mediated Network Impairment and Neurodegeneration in Alzheimer's Disease | 000 | 1 | NIH | 12/5/2024 | $842,175 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG085961 | Investigation into transcriptomic control of dentate granule cell maturation and hyperexcitability in the apoE4 Alzheimer's Disease model | 000 | 2 | NIH | 11/19/2024 | $76,756 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01LM013617 | Image Tools for Computational Cellular Barcoding and Automated Annotation | 000 | 4 | NIH | 12/20/2024 | $358,515 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG085468 | Study Alzheimer's Disease Protective APOE Variants | 000 | 2 | NIH | 11/21/2024 | $847,228 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32HD114427 | Transcriptional variation in human milk | 000 | 2 | NIH | 12/19/2024 | $77,284 |
| | 2025 | 2025 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01ES036325 | Investigating Novel Genetic Variants that Confer Susceptibility to Pesticide-induced Parkinson's Disease | 000 | 1 | NIH | 1/17/2025 | $728,408 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AI180651 | Targeting Feedback Circuitry for Antiviral Therapy | 000 | 1 | NIH | 12/4/2024 | $0 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI109593 | Modulating Stochastic Gene Expression for Cell-fate Control and Therapeutics | 000 | 9 | NIH | 12/4/2024 | -$447,173 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP1DA051144 | A Gene Drive Therapy for HIV: Single-Administration Intervention for High-RiskGroups | 000 | 5 | NIH | 12/18/2024 | -$716,839 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD033362 | Self-Assembling Spike-EBR Nanoparticles as a Vaccine Platform Technology Against SARS-CoV-2 and Future Pandemic Coronaviruses | 002 | 3 | NIH | 10/25/2024 | $1 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD033362 | Self-Assembling Spike-EBR Nanoparticles as a Vaccine Platform Technology Against SARS-CoV-2 and Future Pandemic Coronaviruses | 002 | 3 | NIH | 10/25/2024 | $466,930 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | RF1NS139975 | Vascular-immune mechanisms of cerebral amyloid angiopathy and Alzheimer's pathology | 000 | 1 | NIH | 10/24/2024 | $0 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K00CA245718 | Expanding the scope of protein degradation and stability using chemoproteomic platforms | 000 | 6 | NIH | 10/10/2024 | -$92,430 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP1DA051144 | A Gene Drive Therapy for HIV: Single-Administration Intervention for High-RiskGroups | 004 | 5 | NIH | 3/25/2025 | -$228,161 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AI180651 | Targeting Feedback Circuitry for Antiviral Therapy | 002 | 1 | NIH | 3/25/2025 | -$794,033 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP2HG012442 | SINGLE-CELL CHEMICAL TRANSCRIPTOMIC DISSECTION OF AN ESSENTIAL TRANSCRIPTION FACTOR NETWORK | 001 | 3 | NIH | 2/24/2025 | $1 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI083139 | Role of Factor Acetylation in the Regulation of HIV Transcription | 001 | 15 | NIH | 2/25/2025 | $170,458 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI109593 | Modulating Stochastic Gene Expression for Cell-fate Control and Therapeutics | 003 | 9 | NIH | 3/26/2025 | -$11,230 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI109593 | Modulating Stochastic Gene Expression for Cell-fate Control and Therapeutics | 002 | 9 | NIH | 3/26/2025 | -$55,343 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R25HL121037 | Promoting Underrepresented and Marginalized Populations' Advancement in the Sciences (PUMAS) | 001 | 11 | NIH | 3/27/2025 | $62,600 |
| | 2025 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS128909 | Elucidating microvascular contributions to cognitive impairment at single-cell resolution | 004 | 3 | NIH | 1/6/2025 | $104,557 |
| | 2025 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS128909 | Elucidating microvascular contributions to cognitive impairment at single-cell resolution | 003 | 3 | NIH | 12/18/2024 | -$21,152 |
| | 2025 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS128909 | Elucidating microvascular contributions to cognitive impairment at single-cell resolution | 001 | 3 | NIH | 12/3/2024 | $1,013,873 |
| | 2025 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | P01HL146366 | Combinatorial Regulation of Gene Networks During Cardiac Development and Disease | 000 | 5 | NIH | 10/30/2024 | $0 |
| | 2025 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32HL162450 | Defining the Cellular Morphogenic Behaviors that Shape the Developing Heart | 000 | 2 | NIH | 10/23/2024 | $0 |
| | 2025 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP1DA051144 | A Gene Drive Therapy for HIV: Single-Administration Intervention for High-RiskGroups | 003 | 4 | NIH | 3/25/2025 | -$36,157 |
| | 2025 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP1DA051144 | A Gene Drive Therapy for HIV: Single-Administration Intervention for High-RiskGroups | 002 | 4 | NIH | 3/25/2025 | -$182,612 |
| | 2025 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI083139 | Role of Factor Acetylation in the Regulation of HIV Transcription | 000 | 14 | NIH | 2/25/2025 | -$170,458 |
| | 2025 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R25HL121037 | Promoting Underrepresented and Marginalized Populations' Advancement in the Sciences (PUMAS) | 000 | 10 | NIH | 3/27/2025 | -$62,600 |
| | 2025 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K02NS110973 | Fibrinogen-mediated mechanisms of preterm infant brain injury | 000 | 4 | NIH | 2/20/2025 | $0 |
| | 2025 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL057181 | Cardiogenesis: Molecular Mechanisms | 001 | 28 | NIH | 2/19/2025 | $11,271 |
| | 2025 | 2022 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R33AI140465 | Harnessing the RNA-Binding Properties of Cas13a for HIV-1 Self-Testing | 000 | 5 | NIH | 2/11/2025 | $0 |
| | 2025 | 2022 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD026398 | Redesigning a Neuron's Breath: A Modern Twist to Classical Oxygen Biology | 000 | 6 | NIH | 2/11/2025 | $0 |
| | 2025 | 2022 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R21AI156915 | Targeting Tat/TAR interactions with the superelongation complex to develop novel treatments for HIV/AIDS | 000 | 2 | NIH | 11/22/2024 | -$52 |
| | 2025 | 2022 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL057181 | Cardiogenesis: Molecular Mechanisms | 000 | 27 | NIH | 2/19/2025 | -$11,271 |
| | 2025 | 2021 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R21AI159666 | Identifying and inhibiting the SARS-CoV-2 packaging mechanism | 000 | 1 | NIH | 11/7/2024 | $0 |
| | 2025 | 2021 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP2HG012442 | SINGLE-CELL CHEMICAL TRANSCRIPTOMIC DISSECTION OF AN ESSENTIAL TRANSCRIPTION FACTOR NETWORK | 000 | 2 | NIH | 2/24/2025 | -$1 |
| | 2025 | 2019 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | RF1AG059751 | Proteomic and Genetic Approaches Defining Apolipoprotein E4 Neuropathologic Mechanisms | 000 | 1 | NIH | 10/1/2024 | -$333,355 |
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| Issue Date FY: 2024 ( Subtotal = $39,403,251 ) (Continued on the next page) |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP1DA051144 | A Gene Drive Therapy for HIV: Single-Administration Intervention for High-RiskGroups | 001 | 5 | NIH | 5/1/2024 | $94,500 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP1DA051144 | A Gene Drive Therapy for HIV: Single-Administration Intervention for High-RiskGroups | 000 | 5 | NIH | 3/5/2024 | $850,500 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG065428 | Defining Strategies to Target Energy Failure in Metabolically Vulnerable Human Cells | 000 | 5 | NIH | 4/22/2024 | $620,722 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG071697 | Neuronal ApoE Drives Selective Neurodegeneration in Alzheimer's Disease | 000 | 4 | NIH | 6/13/2024 | $817,317 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32NS127998 | Deconstructing epileptic circuits in a mouse model of SLC6A1 syndrome | 002 | 2 | NIH | 7/9/2024 | -$40,109 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32NS127998 | Deconstructing epileptic circuits in a mouse model of SLC6A1 syndrome | 001 | 2 | NIH | 5/8/2024 | $6,704 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32NS127998 | Deconstructing epileptic circuits in a mouse model of SLC6A1 syndrome | 000 | 2 | NIH | 2/12/2024 | $70,052 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K01AG078485 | Metabolic Vulnerability and Effects of APOE in Human Neurons with Impaired Endocytic Recycling | 000 | 3 | NIH | 5/9/2024 | $130,950 |
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