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 | Issue Date FY: 2025 ( Subtotal = $41,146 ) |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | RF1NS139975 | Vascular-immune mechanisms of cerebral amyloid angiopathy and Alzheimer's pathology | 000 | 1 | NIH | 10/24/2024 | $0 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD033362 | Self-Assembling Spike-EBR Nanoparticles as a Vaccine Platform Technology Against SARS-CoV-2 and Future Pandemic Coronaviruses | 002 | 3 | NIH | 10/25/2024 | $1 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD033362 | Self-Assembling Spike-EBR Nanoparticles as a Vaccine Platform Technology Against SARS-CoV-2 and Future Pandemic Coronaviruses | 002 | 3 | NIH | 10/25/2024 | $466,930 |
| | 2025 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K00CA245718 | Expanding the scope of protein degradation and stability using chemoproteomic platforms | 000 | 6 | NIH | 10/10/2024 | -$92,430 |
| | 2025 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | P01HL146366 | Combinatorial Regulation of Gene Networks During Cardiac Development and Disease | 000 | 5 | NIH | 10/30/2024 | $0 |
| | 2025 | 2023 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32HL162450 | Defining the Cellular Morphogenic Behaviors that Shape the Developing Heart | 000 | 2 | NIH | 10/23/2024 | $0 |
| | 2025 | 2021 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R21AI159666 | Identifying and inhibiting the SARS-CoV-2 packaging mechanism | 000 | 1 | NIH | 11/7/2024 | $0 |
| | 2025 | 2019 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | RF1AG059751 | Proteomic and Genetic Approaches Defining Apolipoprotein E4 Neuropathologic Mechanisms | 000 | 1 | NIH | 10/1/2024 | -$333,355 |
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| Issue Date FY: 2024 ( Subtotal = $39,403,251 ) (Continued on the next page) |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI109593 | Modulating Stochastic Gene Expression for Cell-fate Control and Therapeutics | 000 | 9 | NIH | 3/5/2024 | $826,602 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS121287 | Role of Myeloid And CD4+ T Immune Cells in Post-Traumatic Plasticity | 002 | 3 | NIH | 1/29/2024 | $71,820 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R37AI109593 | Modulating Stochastic Gene Expression for Cell-fate Control and Therapeutics | 001 | 9 | NIH | 3/7/2024 | $95,634 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS121287 | Role of Myeloid And CD4+ T Immune Cells in Post-Traumatic Plasticity | 001 | 3 | NIH | 1/26/2024 | $71,820 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01LM013617 | Image Tools for Computational Cellular Barcoding and Automated Annotation | 000 | 3 | NIH | 12/21/2023 | $358,515 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32HD114427 | Transcriptional variation in human milk | 000 | 1 | NIH | 12/15/2023 | $69,080 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01DK123746 | Modeling intestinal dysfunction in HIV infection with organoid technology | 000 | 5 | NIH | 12/20/2023 | $710,788 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01NS121287 | Role of Myeloid And CD4+ T Immune Cells in Post-Traumatic Plasticity | 000 | 3 | NIH | 11/28/2023 | $371,162 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32NS127998 | Deconstructing epileptic circuits in a mouse model of SLC6A1 syndrome | 000 | 2 | NIH | 2/12/2024 | $70,052 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | P01AG073082 | Decoding the Multifactorial Etiology of Neural Network Dysfunction in Alzheimer's Disease | 000 | 4 | NIH | 8/9/2024 | $4,657,774 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32NS127998 | Deconstructing epileptic circuits in a mouse model of SLC6A1 syndrome | 001 | 2 | NIH | 5/8/2024 | $6,704 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32NS127998 | Deconstructing epileptic circuits in a mouse model of SLC6A1 syndrome | 002 | 2 | NIH | 7/9/2024 | -$40,109 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG071697 | Neuronal ApoE Drives Selective Neurodegeneration in Alzheimer's Disease | 000 | 4 | NIH | 6/13/2024 | $817,317 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AI183286 | Targeting the transcriptionally-active reservoir to reduce chronic inflammation in aged people with HIV | 000 | 1 | NIH | 2/26/2024 | $915,998 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K00CA245718 | Expanding the scope of protein degradation and stability using chemoproteomic platforms | 000 | 6 | NIH | 7/29/2024 | $0 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG085468 | Study Alzheimer's Disease Protective APOE Variants | 000 | 1 | NIH | 12/14/2023 | $941,364 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG085961 | Investigation into transcriptomic control of dentate granule cell maturation and hyperexcitability in the apoE4 Alzheimer's Disease model | 002 | 1 | NIH | 1/30/2024 | $0 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG085961 | Investigation into transcriptomic control of dentate granule cell maturation and hyperexcitability in the apoE4 Alzheimer's Disease model | 003 | 1 | NIH | 4/30/2024 | $4,784 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01CA276368 | Decoding and reprogramming T cells through synthetic biology for cancer immunotherapy | 001 | 2 | NIH | 4/19/2024 | $37,462 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG085961 | Investigation into transcriptomic control of dentate granule cell maturation and hyperexcitability in the apoE4 Alzheimer's Disease model | 001 | 1 | NIH | 11/8/2023 | $0 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | F32AG085961 | Investigation into transcriptomic control of dentate granule cell maturation and hyperexcitability in the apoE4 Alzheimer's Disease model | 000 | 1 | NIH | 11/8/2023 | $69,500 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01CA276368 | Decoding and reprogramming T cells through synthetic biology for cancer immunotherapy | 000 | 2 | NIH | 12/6/2023 | $674,325 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AI180651 | Targeting Feedback Circuitry for Antiviral Therapy | 001 | 1 | NIH | 6/3/2024 | $94,500 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AI180651 | Targeting Feedback Circuitry for Antiviral Therapy | 000 | 1 | NIH | 12/11/2023 | $850,489 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD036170 | Transfer learning leveraging large-scale transcriptomics to map disrupted gene networks in cardiovascular disease | 000 | 2 | NIH | 8/12/2024 | $472,499 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD036170 | Transfer learning leveraging large-scale transcriptomics to map disrupted gene networks in cardiovascular disease | 000 | 2 | NIH | 8/12/2024 | $1 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD036170 | Transfer learning leveraging large-scale transcriptomics to map disrupted gene networks in cardiovascular disease | 001 | 2 | NIH | 8/29/2024 | $0 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD036170 | Transfer learning leveraging large-scale transcriptomics to map disrupted gene networks in cardiovascular disease | 001 | 2 | NIH | 8/29/2024 | $0 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R21AI184073 | Targeting CD127-expressing tissue reservoir cells as a strategy for HIV cure | 000 | 1 | NIH | 8/6/2024 | $250,791 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD033362 | Self-Assembling Spike-EBR Nanoparticles as a Vaccine Platform Technology Against SARS-CoV-2 and Future Pandemic Coronaviruses | 001 | 3 | NIH | 9/12/2024 | $1 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP5OD033362 | Self-Assembling Spike-EBR Nanoparticles as a Vaccine Platform Technology Against SARS-CoV-2 and Future Pandemic Coronaviruses | 001 | 3 | NIH | 9/12/2024 | $472,499 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG065540 | Study the Protective Roles of ApoE2 in Alzheimer's Disease Using Reprogrammed Isogenic Cells | 000 | 5 | NIH | 4/18/2024 | $724,286 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01DA059551 | Sorting and Sequencing Latent Reservoirs in HIV+ Opioid Users | 000 | 2 | NIH | 7/30/2024 | $1,560,507 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01DK131526 | Multiomics characterization, induction, and elimination of the HIV gut reservoir | 000 | 3 | NIH | 5/8/2024 | $695,727 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | K01HL173644 | Addressing Disparities in Polygenic Risk Score for Coronary Heart Diseases in Diverse Populations | 000 | 1 | NIH | 6/29/2024 | $179,280 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL155906 | Gene regulatory networks for heart development | 001 | 4 | NIH | 6/14/2024 | $48,008 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL155906 | Gene regulatory networks for heart development | 000 | 4 | NIH | 1/3/2024 | $540,091 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01HL163268 | Small molecule therapeutic for calcific aortic valve disease | 000 | 2 | NIH | 5/7/2024 | $782,141 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | DP1DA051144 | A Gene Drive Therapy for HIV: single-administration intervention for high-risk groups | 001 | 5 | NIH | 5/1/2024 | $94,500 |
| | 2024 | 2024 | J.DAVID GLADSTONE INSTITUTES | 1650 OWENS ST | SAN FRANCISCO | CA | 94158-2261 | SAN FRANCISCO | USA | R01AG078164 | Develop AD Connectivity Maps with Human iPSC-Derived Brain Cells and their Use | 000 | 3 | NIH | 5/15/2024 | $941,764 |
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