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 | Issue Date FY: 2025 ( Subtotal = $28,898,864 ) (Continued on the next page) |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA266216 | Induction of interferon response by chromatin damaging anti-cancer therapy | 001 | 2 | NIH | 6/17/2025 | $39,688 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA266216 | Induction of interferon response by chromatin damaging anti-cancer therapy | 000 | 2 | NIH | 11/25/2024 | $357,193 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA275081 | Impact of RB activation on the pancreatic cancer epigenome and tumor microenvironment | 000 | 3 | NIH | 6/23/2025 | $505,216 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01MH126282 | Investigating how stress induced changes in maternal serotonin affect offspring development and stress resilience | 000 | 5 | NIH | 4/28/2025 | $364,862 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA267647 | Delineating the dystopian nature of the cell cycle in cancer | 001 | 4 | NIH | 5/22/2025 | $53,496 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA267647 | Delineating the dystopian nature of the cell cycle in cancer | 000 | 4 | NIH | 4/29/2025 | $481,463 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01HL167232 | Targeting CD83 to reduce leukemia relapse and GVHD after allogeneichematopoietic cell transplantation | 003 | 3 | NIH | 7/9/2025 | $71,188 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01HL167232 | Targeting CD83 to reduce leukemia relapse and GVHD after allogeneichematopoietic cell transplantation | 002 | 3 | NIH | 4/2/2025 | $640,704 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA255515 | Metformin for chemoprevention of lung cancer in obese subjects at high risk | 000 | 5 | NIH | 8/1/2025 | $583,338 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | UG1CA233191 | Network Lead Academic Participating Site Grant from the Roswell Park Cancer Institute | 000 | 6 | NIH | 3/18/2025 | $276,387 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R50CA211108 | Associate-Director Flow and Image Cytometry Roswell Park ComprehensiveCancer Center | 000 | 9 | NIH | 7/23/2025 | $342,107 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | UH3CA260602 | Disparities in REsults of Immune Checkpoint Inhibitor Treatment (DiRECT): A Prospective Cohort Study of Cancer Survivors Treated with anti-PD-1/anti-PD-L1 in a Community Oncology Setting | 001 | 5 | NIH | 6/25/2025 | $2,425,687 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA283547 | Interstitial Photodynamic Therapy Following Palliative Radiotherapy for Patients with Inoperable Malignant Central Airway Obstruction | 002 | 2 | NIH | 8/5/2025 | $76,836 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA283547 | Interstitial Photodynamic Therapy Following Palliative Radiotherapy for Patients with Inoperable Malignant Central Airway Obstruction | 001 | 2 | NIH | 6/18/2025 | $67,546 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA283547 | Interstitial Photodynamic Therapy Following Palliative Radiotherapy for Patients with Inoperable Malignant Central Airway Obstruction | 000 | 2 | NIH | 2/14/2025 | $607,916 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01ES034250 | STAG2 modulates environmental toxicant exposures and epigenomic heterogeneity | 000 | 4 | NIH | 12/11/2024 | $597,213 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA283501 | MedSupport: A Novel Multilevel Intervention to Identify and Address Barriers to Pediatric Medication | 000 | 2 | NIH | 3/28/2025 | $612,506 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | K08CA286765 | Leveraging small molecule inhibitors to improve CD19 CAR T cell immunotherapy for KMT2A-rearranged ALL | 005 | 3 | NIH | 6/24/2025 | $196,110 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | U24CA274159 | Coordinating and Data Management Center for Acquired Resistance to Therapy Network | 000 | 3 | NIH | 4/3/2025 | $74,605 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA248018 | Leveraging the GTP Biosynthetic Pathway for Anti-Tumor Therapies | 001 | 5 | NIH | 6/11/2025 | $38,354 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA248018 | Leveraging the GTP Biosynthetic Pathway for Anti-Tumor Therapies | 000 | 5 | NIH | 11/25/2024 | $345,191 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA243456 | Radiogenomic Credentialing of Head and Neck Cancer Models | 001 | 5 | NIH | 6/4/2025 | $57,477 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA243456 | Radiogenomic Credentialing of Head and Neck Cancer Models | 000 | 5 | NIH | 11/25/2024 | $517,298 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R35GM148071 | The Genetic Basis of Human DNA Replication Timing | 003 | 3 | NIH | 8/12/2025 | $45,804 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R35GM148071 | The Genetic Basis of Human DNA Replication Timing | 002 | 3 | NIH | 2/26/2025 | $412,236 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA262822 | Role of type 2 immune response in pancreatic cancer tumorigenesis | 000 | 5 | NIH | 7/17/2025 | $404,550 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA262822 | Role of type 2 immune response in pancreatic cancer tumorigenesis | 001 | 5 | NIH | 8/5/2025 | $71,398 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | F30CA284763 | Understanding the role of β2AR-signaling on ILC2 differentiation/plasticity and its implications in cancer progression | 000 | 3 | NIH | 7/31/2025 | $54,538 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA282430 | Novel synthetic lethality strategy for TP53 mutant colorectal cancer | 000 | 3 | NIH | 8/5/2025 | $542,949 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01DA057228 | Assessing pharmacokinetic and pharmacodynamic variability of Δ9-tetrahydrocannabinol delivered from vaping products with and without concurrent use of nicotine | 000 | 4 | NIH | 7/2/2025 | $651,235 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA278802 | TLR5 enhancement of liver-directed radiotherapy plus immune checkpoint blockade against irradiated liver metastasis and abscopal tumors | 000 | 3 | NIH | 4/24/2025 | $635,299 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA278802 | TLR5 enhancement of liver-directed radiotherapy plus immune checkpoint blockade against irradiated liver metastasis and abscopal tumors | 001 | 3 | NIH | 5/29/2025 | $70,589 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | F31CA306124 | Modulating costimulation in CAR T cells to enhance antitumor efficacy | 000 | 1 | NIH | 7/3/2025 | $35,090 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | F31CA306124 | Modulating costimulation in CAR T cells to enhance antitumor efficacy | 001 | 1 | NIH | 7/3/2025 | $0 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA275961 | Targeting HNF1A-mediated therapeutic resistance in pancreatic ductal adenocarcinoma | 001 | 3 | NIH | 6/11/2025 | $51,887 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA275961 | Targeting HNF1A-mediated therapeutic resistance in pancreatic ductal adenocarcinoma | 000 | 3 | NIH | 11/27/2024 | $466,991 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA279440 | The Immunomodulatory Function of Cyclin E1 in Ovarian Cancer and Therapeutic Targeting | 001 | 2 | NIH | 5/22/2025 | $50,584 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA279440 | The Immunomodulatory Function of Cyclin E1 in Ovarian Cancer and Therapeutic Targeting | 000 | 2 | NIH | 3/10/2025 | $455,267 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA273231 | Dissecting the Mechanism of SETDB1 and its K867 Monoubiquitination in Lung Cancer Progression | 000 | 4 | NIH | 7/22/2025 | $402,086 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R50CA283805 | Director Genomics Shared Resource | 000 | 2 | NIH | 7/23/2025 | $236,003 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA267690 | Targeting complement to enhance antitumor immunity and control malignant effusions in patients with recurrent epithelial ovarian cancer | 000 | 4 | NIH | 7/1/2025 | $642,760 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | K08CA252161 | Therapeutic implication of RB1 loss in bladder cancer | 000 | 5 | NIH | 1/15/2025 | $285,729 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA252092 | Mechanisms of metabolic stress-induced transcriptional regulation in prostate cancer | 001 | 5 | NIH | 5/22/2025 | $37,906 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA252092 | Mechanisms of metabolic stress-induced transcriptional regulation in prostate cancer | 000 | 5 | NIH | 4/28/2025 | $341,164 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA262899 | Multi-ethnic high-throughput study to identify novel non-HLA genetic contributors to mortality after blood and marrow transplantation | 000 | 5 | NIH | 8/4/2025 | $605,569 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA272771 | The role of USP27X-Cyclin D1 axis in HER2 Therapy Resistant Breast Cancer | 001 | 3 | NIH | 5/22/2025 | $43,778 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA272771 | The role of USP27X-Cyclin D1 axis in HER2 Therapy Resistant Breast Cancer | 000 | 3 | NIH | 3/3/2025 | $394,006 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA250412 | Impact of Circulating Myeloid Cell Clusters on Anti-Tumor Immunity | 001 | 5 | NIH | 6/4/2025 | $69,715 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA250412 | Impact of Circulating Myeloid Cell Clusters on Anti-Tumor Immunity | 000 | 5 | NIH | 12/18/2024 | $627,451 |
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