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 | Issue Date FY: 2025 ( Subtotal = $15,660,387 ) (Continued on the next page) |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA283501 | MedSupport: A Novel Multilevel Intervention to Identify and Address Barriers to Pediatric Medication | 000 | 2 | NIH | 3/28/2025 | $612,506 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA248018 | Leveraging the GTP Biosynthetic Pathway for Anti-Tumor Therapies | 001 | 5 | NIH | 6/11/2025 | $38,354 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA248018 | Leveraging the GTP Biosynthetic Pathway for Anti-Tumor Therapies | 000 | 5 | NIH | 11/25/2024 | $345,191 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R35GM148071 | The Genetic Basis of Human DNA Replication Timing | 002 | 3 | NIH | 2/26/2025 | $412,236 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA243456 | Radiogenomic Credentialing of Head and Neck Cancer Models | 001 | 5 | NIH | 6/4/2025 | $57,477 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA243456 | Radiogenomic Credentialing of Head and Neck Cancer Models | 000 | 5 | NIH | 11/25/2024 | $517,298 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA278802 | TLR5 enhancement of liver-directed radiotherapy plus immune checkpoint blockade against irradiated liver metastasis and abscopal tumors | 000 | 3 | NIH | 4/24/2025 | $635,299 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA278802 | TLR5 enhancement of liver-directed radiotherapy plus immune checkpoint blockade against irradiated liver metastasis and abscopal tumors | 001 | 3 | NIH | 5/29/2025 | $70,589 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA275961 | Targeting HNF1A-mediated therapeutic resistance in pancreatic ductal adenocarcinoma | 001 | 3 | NIH | 6/11/2025 | $51,887 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA275961 | Targeting HNF1A-mediated therapeutic resistance in pancreatic ductal adenocarcinoma | 000 | 3 | NIH | 11/27/2024 | $466,991 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | K08CA252161 | Therapeutic implication of RB1 loss in bladder cancer | 000 | 5 | NIH | 1/15/2025 | $285,729 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA252092 | Mechanisms of metabolic stress-induced transcriptional regulation in prostate cancer | 001 | 5 | NIH | 5/22/2025 | $37,906 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA252092 | Mechanisms of metabolic stress-induced transcriptional regulation in prostate cancer | 000 | 5 | NIH | 4/28/2025 | $341,164 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA250412 | Impact of Circulating Myeloid Cell Clusters on Anti-Tumor Immunity | 001 | 5 | NIH | 6/4/2025 | $69,715 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA250412 | Impact of Circulating Myeloid Cell Clusters on Anti-Tumor Immunity | 000 | 5 | NIH | 12/18/2024 | $627,451 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01HL150266 | Inhibition of Radiation-Induced Coronary Microvascular Disease | 000 | 5 | NIH | 12/10/2024 | $411,136 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA296175 | A scalable cruciferous vegetable intervention to reduce bladder cancer recurrence and progression | 001 | 1 | NIH | 5/1/2025 | $0 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA296175 | A scalable cruciferous vegetable intervention to reduce bladder cancer recurrence and progression | 000 | 1 | NIH | 3/7/2025 | $717,150 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA258337 | Behavioral Parenting Skills as a Novel Target for Improving Pediatric Medication Adherence | 000 | 4 | NIH | 12/24/2024 | $572,254 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA285707 | Determining the Impact of Metabolic Adaptations on the Immune-Tumor Microenvironment in Metastatic Breast Cancer | 000 | 1 | NIH | 12/16/2024 | $719,799 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA266216 | Induction of interferon response by chromatin damaging anti-cancer therapy | 000 | 2 | NIH | 11/25/2024 | $357,193 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA267647 | Delineating the dystopian nature of the cell cycle in cancer | 001 | 4 | NIH | 5/22/2025 | $53,496 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA267647 | Delineating the dystopian nature of the cell cycle in cancer | 000 | 4 | NIH | 4/29/2025 | $481,463 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01MH126282 | Investigating how stress induced changes in maternal serotonin affect offspring development and stress resilience | 000 | 5 | NIH | 4/28/2025 | $364,862 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01HL167232 | Targeting CD83 to reduce leukemia relapse and GVHD after allogeneichematopoietic cell transplantation | 002 | 3 | NIH | 4/2/2025 | $640,704 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | UG1CA233191 | Network Lead Academic Participating Site Grant from the Roswell Park Cancer Institute | 000 | 6 | NIH | 3/18/2025 | $276,387 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA251545 | Functional Significance of individual p53 mutations in determining the role of estrogen receptor beta in triple negative breast cancer | 001 | 5 | NIH | 5/22/2025 | $55,745 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA251545 | Functional Significance of individual p53 mutations in determining the role of estrogen receptor beta in triple negative breast cancer | 000 | 5 | NIH | 2/13/2025 | $501,703 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01AI155499 | Understanding mechanisms and consequences of T cell co-receptor regulated RNA maturation | 000 | 5 | NIH | 3/14/2025 | $501,412 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R03CA289559 | Linking lifestyles with tumor immune profiles to identify strategies for improving breast cancer outcomes | 000 | 2 | NIH | 3/3/2025 | $86,750 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA240290 | Novel Therapeutic Strategies to Co-Target Undifferentiated Prostate Cancer (PCa) Stem Cells and Bulk PCa Cells | 000 | 6 | NIH | 3/20/2025 | $473,358 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | U01CA256801 | Optimizing Dual-Targeted and Dual-Armored CAR T Cells for Small Cell LungCancer | 001 | 5 | NIH | 5/22/2025 | $70,456 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | U01CA256801 | Optimizing Dual-Targeted and Dual-Armored CAR T Cells for Small Cell LungCancer | 000 | 5 | NIH | 3/5/2025 | $626,345 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA272771 | The role of USP27X-Cyclin D1 axis in HER2 Therapy Resistant Breast Cancer | 001 | 3 | NIH | 5/22/2025 | $43,778 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA272771 | The role of USP27X-Cyclin D1 axis in HER2 Therapy Resistant Breast Cancer | 000 | 3 | NIH | 3/3/2025 | $394,006 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA279440 | The Immunomodulatory Function of Cyclin E1 in Ovarian Cancer and Therapeutic Targeting | 001 | 2 | NIH | 5/22/2025 | $50,584 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA279440 | The Immunomodulatory Function of Cyclin E1 in Ovarian Cancer and Therapeutic Targeting | 000 | 2 | NIH | 3/10/2025 | $455,267 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA292730 | Decipher the Molecular Mechanisms of Breast Cancer Bone Metastasis | 000 | 1 | NIH | 3/11/2025 | $700,690 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA283547 | Interstitial Photodynamic Therapy Following Palliative Radiotherapy for Patients with Inoperable Malignant Central Airway Obstruction | 000 | 2 | NIH | 2/14/2025 | $607,916 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA255242 | Advancing skin cancer prevention by tackling UV-induced clonogenic mutations | 000 | 5 | NIH | 2/14/2025 | $576,303 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R21CA288931 | Combined inhibition of ATR and p110β as Therapy in PTEN-deficient Prostate Cancer | 001 | 2 | NIH | 5/22/2025 | $24,334 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R21CA288931 | Combined inhibition of ATR and p110β as Therapy in PTEN-deficient Prostate Cancer | 000 | 2 | NIH | 3/3/2025 | $219,000 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | U24CA274159 | Coordinating and Data Management Center for Acquired Resistance to Therapy Network | 000 | 3 | NIH | 4/3/2025 | $74,605 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01ES034250 | STAG2 modulates environmental toxicant exposures and epigenomic heterogeneity | 000 | 4 | NIH | 12/11/2024 | $597,213 |
| | 2025 | 2024 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | K08CA286765 | Leveraging small molecule inhibitors to improve CD19 CAR T cell immunotherapy for KMT2A-rearranged ALL | 003 | 2 | NIH | 12/23/2024 | -$6,856 |
| | 2025 | 2024 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | K08CA286765 | Leveraging small molecule inhibitors to improve CD19 CAR T cell immunotherapy for KMT2A-rearranged ALL | 001 | 2 | NIH | 12/20/2024 | $179,046 |
| | 2025 | 2024 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | K08CA279766 | Stress-induced immunosuppression via downregulation of interferon in triple negative breast cancer | 000 | 1 | NIH | 5/19/2025 | -$156,562 |
| | 2025 | 2024 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R35GM148071 | The Genetic Basis of Human DNA Replication Timing | 001 | 2 | NIH | 1/13/2025 | $76,340 |
| | 2025 | 2024 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01MD016850 | Implementation of evidence-based strategies to optimize HPV vaccination in rural primary care settings | 000 | 3 | NIH | 6/11/2025 | $0 |
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