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 | Issue Date FY: 2025 ( Subtotal = $42,641,920 ) (Continued on the next page) |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R50CA283761 | Development of New Technologies at Roswell Park to Further Cancer-Based Research and Treatment Through Genome Modification | 000 | 3 | NIH | 8/18/2025 | $324,868 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA282430 | Novel synthetic lethality strategy for TP53 mutant colorectal cancer | 000 | 3 | NIH | 8/5/2025 | $542,949 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01DA057228 | Assessing pharmacokinetic and pharmacodynamic variability of Δ9-tetrahydrocannabinol delivered from vaping products with and without concurrent use of nicotine | 000 | 4 | NIH | 7/2/2025 | $651,235 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01MD016850 | Implementation of evidence-based strategies to optimize HPV vaccination in rural primary care settings | 003 | 4 | NIH | 9/8/2025 | $661,573 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA281862 | A Multi-Institute Survivorship Study of Patients Living with Advanced Cancer Who Have Had Durable Response to Immune Checkpoint Inhibitors | 001 | 3 | NIH | 8/21/2025 | $766,294 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA278802 | TLR5 enhancement of liver-directed radiotherapy plus immune checkpoint blockade against irradiated liver metastasis and abscopal tumors | 001 | 3 | NIH | 5/29/2025 | $70,589 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA278802 | TLR5 enhancement of liver-directed radiotherapy plus immune checkpoint blockade against irradiated liver metastasis and abscopal tumors | 000 | 3 | NIH | 4/24/2025 | $635,299 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA275961 | Targeting HNF1A-mediated therapeutic resistance in pancreatic ductal adenocarcinoma | 001 | 3 | NIH | 6/11/2025 | $51,887 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R37CA275961 | Targeting HNF1A-mediated therapeutic resistance in pancreatic ductal adenocarcinoma | 000 | 3 | NIH | 11/27/2024 | $466,991 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA273231 | Dissecting the Mechanism of SETDB1 and its K867 Monoubiquitination in Lung Cancer Progression | 000 | 4 | NIH | 7/22/2025 | $402,086 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R50CA283805 | Director Genomics Shared Resource | 000 | 2 | NIH | 7/23/2025 | $236,003 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA267690 | Targeting complement to enhance antitumor immunity and control malignant effusions in patients with recurrent epithelial ovarian cancer | 000 | 4 | NIH | 7/1/2025 | $642,760 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | K08CA252161 | Therapeutic implication of RB1 loss in bladder cancer | 000 | 5 | NIH | 1/15/2025 | $285,729 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA252092 | Mechanisms of metabolic stress-induced transcriptional regulation in prostate cancer | 001 | 5 | NIH | 5/22/2025 | $37,906 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA252092 | Mechanisms of metabolic stress-induced transcriptional regulation in prostate cancer | 000 | 5 | NIH | 4/28/2025 | $341,164 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA257480 | Transcriptomic classification of non-muscle invasive bladder cancer and its clinical and prognostic implication | 001 | 4 | NIH | 9/2/2025 | $2,683,351 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01HL150266 | Inhibition of Radiation-Induced Coronary Microvascular Disease | 000 | 5 | NIH | 12/10/2024 | $411,136 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA250412 | Impact of Circulating Myeloid Cell Clusters on Anti-Tumor Immunity | 001 | 5 | NIH | 6/4/2025 | $69,715 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA250412 | Impact of Circulating Myeloid Cell Clusters on Anti-Tumor Immunity | 000 | 5 | NIH | 12/18/2024 | $627,451 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | F99CA294065 | Metabolic Reprogramming of Myeloid Cells to Enhance Cancer Immunotherapy | 000 | 2 | NIH | 7/31/2025 | $34,356 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R35CA197616 | Advancing Cancer Therapy through Groundbreaking Research in Radiation Biology | 000 | 11 | NIH | 8/29/2025 | $829,136 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | P50CA159981 | Roswell Park Ovarian Cancer SPORE | 001 | 11 | NIH | 9/10/2025 | $1,787,915 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R25CA181003 | Summer Research Experiences in Quantitative Cancer Sciences and Emerging Technologies | 003 | 11 | NIH | 8/4/2025 | $0 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA298812 | Assessing the impact of the substantial equivalence mechanism on the cigarette and cigar markets | 001 | 1 | NIH | 9/25/2025 | -$816,307 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R50LM015262 | Investing in Research Software Engineering for Expert Development and Dissemination of Bioconductor | 000 | 1 | NIH | 9/11/2025 | $168,448 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA298812 | Assessing the impact of the substantial equivalence mechanism on the cigarette and cigar markets | 000 | 1 | NIH | 9/12/2025 | $816,307 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA298812 | Assessing the impact of the substantial equivalence mechanism on the cigarette and cigar markets | 001 | 1 | NIH | 9/25/2025 | $816,307 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | U01CA256801 | Optimizing Dual-Targeted and Dual-Armored CAR T Cells for Small Cell LungCancer | 000 | 5 | NIH | 3/5/2025 | $626,345 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | F30CA294838 | Genetic and Ancestral Determinants of Pathological and Molecular Tumor Immune Phenotypes in A Multi-Ethnic Population of Breast Cancer Patients: An Evolutionary Perspective | 001 | 1 | NIH | 8/25/2025 | $0 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | F30CA294838 | Genetic and Ancestral Determinants of Pathological and Molecular Tumor Immune Phenotypes in A Multi-Ethnic Population of Breast Cancer Patients: An Evolutionary Perspective | 000 | 1 | NIH | 8/25/2025 | $42,256 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | U01CA256801 | Optimizing Dual-Targeted and Dual-Armored CAR T Cells for Small Cell LungCancer | 001 | 5 | NIH | 5/22/2025 | $70,456 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01AI155499 | Understanding mechanisms and consequences of T cell co-receptor regulated RNA maturation | 000 | 5 | NIH | 3/14/2025 | $501,412 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | U24CA305623 | Cancer Immunoprevention Network (CIP-Net) Resource Coordinating Center | 001 | 1 | NIH | 9/16/2025 | $0 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | U24CA305623 | Cancer Immunoprevention Network (CIP-Net) Resource Coordinating Center | 000 | 1 | NIH | 8/22/2025 | $825,857 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R03CA289559 | Linking lifestyles with tumor immune profiles to identify strategies for improving breast cancer outcomes | 000 | 2 | NIH | 3/3/2025 | $86,750 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA240290 | Novel Therapeutic Strategies to Co-Target Undifferentiated Prostate Cancer (PCa) Stem Cells and Bulk PCa Cells | 000 | 6 | NIH | 3/20/2025 | $473,358 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R03CA299053 | Investigation of the effects of CXCR1/2 inhibition on the immune microenvironment of patients with multiple myeloma | 000 | 1 | NIH | 8/6/2025 | $173,500 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA251545 | Functional Significance of individual p53 mutations in determining the role of estrogen receptor beta in triple negative breast cancer | 001 | 5 | NIH | 5/22/2025 | $55,745 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA251545 | Functional Significance of individual p53 mutations in determining the role of estrogen receptor beta in triple negative breast cancer | 000 | 5 | NIH | 2/13/2025 | $501,703 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R21CA288931 | Combined inhibition of ATR and p110β as Therapy in PTEN-deficient Prostate Cancer | 001 | 2 | NIH | 5/22/2025 | $24,334 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R21CA288931 | Combined inhibition of ATR and p110β as Therapy in PTEN-deficient Prostate Cancer | 000 | 2 | NIH | 3/3/2025 | $219,000 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | P30CA016056 | Roswell Park CCSG Admin Supplement: Close out EDDOP Studies | 005 | 48 | NIH | 7/31/2025 | $4,468,904 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | P30CA016056 | Roswell Park CCSG Admin Supplement: Close out EDDOP Studies | 004 | 47 | NIH | 4/1/2025 | $45,412 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA255242 | Advancing skin cancer prevention by tackling UV-induced clonogenic mutations | 001 | 5 | NIH | 6/18/2025 | $64,033 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA255242 | Advancing skin cancer prevention by tackling UV-induced clonogenic mutations | 000 | 5 | NIH | 2/14/2025 | $576,303 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | P30CA016056 | Roswell Park CCSG Admin Supplement: Close out EDDOP Studies | 003 | 46 | NIH | 2/26/2025 | $99,601 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | F31CA306124 | Modulating costimulation in CAR T cells to enhance antitumor efficacy | 001 | 1 | NIH | 7/3/2025 | $0 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | F31CA306124 | Modulating costimulation in CAR T cells to enhance antitumor efficacy | 000 | 1 | NIH | 7/3/2025 | $35,090 |
| | 2025 | 2025 | HEALTH RESEARCH, INC. | 665 ELM ST | BUFFALO | NY | 14203-1104 | ERIE | USA | R01CA283547 | Interstitial Photodynamic Therapy Following Palliative Radiotherapy for Patients with Inoperable Malignant Central Airway Obstruction | 002 | 2 | NIH | 8/5/2025 | $76,836 |
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