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 | Issue Date FY: 2025 ( Subtotal = $9,562,670 ) |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | AY2AX000072 | Personalized Analytics for Transforming Healthcare (PATH) | 001 | 1 | NIH | 10/30/2024 | -$9,600,740 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | AY2AX000072 | Personalized Analytics for Transforming Healthcare (PATH) | 001 | 1 | NIH | 10/30/2024 | $9,600,740 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | AY2AX000072 | Personalized Analytics for Transforming Healthcare (PATH) | 000 | 1 | NIH | 10/23/2024 | $9,600,740 |
| | 2025 | 2021 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DA041742 | Molecular Mechanisms of HIV Latency | 001 | 6 | NIH | 11/12/2024 | -$5,363 |
| | 2025 | 2021 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DA041742 | Molecular Mechanisms of HIV Latency | 000 | 6 | NIH | 11/12/2024 | -$32,707 |
|
| Issue Date FY: 2024 ( Subtotal = $26,618,426 ) (Continued on the next page) |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG075201 | Multidimensional mapping of proteome changes and mechanisms underlying yeast replicative aging | 000 | 3 | NIH | 4/22/2024 | $558,796 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG072791 | Role of Selective Autophagy in Organismal Health | 000 | 3 | NIH | 4/24/2024 | $526,081 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R25AG086096 | Support and Preparation for an Alzheimer's Research Career | 000 | 1 | NIH | 5/20/2024 | $432,000 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068288 | Methylglyoxal drives astrocyte senescence to mediate neurodegeneration in Alzheimer's disease | 002 | 5 | NIH | 7/23/2024 | $485,000 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U54AG075932 | Senescent cell mapping, identification and validation for human somatic and reproductive tissues | 002 | 4 | NIH | 8/23/2024 | $2,390,550 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P30AG068345 | The University of Southern California and Buck Institute Nathan Shock Center | 002 | 5 | NIH | 6/5/2024 | $923,306 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P30AG068345 | The University of Southern California and Buck Institute Nathan Shock Center | 001 | 4 | NIH | 3/26/2024 | $128,201 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | UH3CA268105 | Evaluating diverse technologies for detecting and validating senescent cells in vivo | 002 | 4 | NIH | 8/28/2024 | $909,684 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U01AI180158 | Cellular senescence and Associated Lysosomal Dysfunction in Immune Aging | 001 | 1 | NIH | 9/19/2024 | $0 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | T32AG000266 | Training in Basic Research on Aging and Age-Related Disease | 004 | 26 | NIH | 5/31/2024 | $842,182 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U01AI180158 | Cellular senescence and Associated Lysosomal Dysfunction in Immune Aging | 000 | 1 | NIH | 2/26/2024 | $692,640 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG067333 | Mechanisms of the signaling metabolite β-hydroxybutyrate in Alzheimer's disease and the aging brain | 000 | 5 | NIH | 6/11/2024 | $758,000 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068025 | Geroscience metabolites beta-hydroxybutyrate and NAD+ linking inflammation and neuroenergetic failure in delirium | 002 | 5 | NIH | 6/7/2024 | $115,399 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068025 | Geroscience metabolites beta-hydroxybutyrate and NAD+ linking inflammation and neuroenergetic failure in delirium | 001 | 5 | NIH | 6/4/2024 | $766,837 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068025 | Geroscience metabolites beta-hydroxybutyrate and NAD+ linking inflammation and neuroenergetic failure in delirium | 000 | 4 | NIH | 10/26/2023 | $67,316 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R56NS135053 | Regulation of synaptic activity by mRNA methylation | 000 | 1 | NIH | 8/29/2024 | $522,134 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R56NS135053 | Regulation of synaptic activity by mRNA methylation | 001 | 1 | NIH | 9/23/2024 | $154,655 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U01AG045844 | Caenorhabditis Intervention Testing Program - Buck Institute | 001 | 11 | NIH | 6/28/2024 | $641,771 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DK135807 | Novel components of mitochondrial regulation of insulin secretion in type 2 diabetes | 000 | 1 | NIH | 12/8/2023 | $670,313 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R13AG082490 | The Reproductive Aging Conference | 000 | 2 | NIH | 3/20/2024 | $49,000 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG071995 | The role of diet and aging in photoreceptor homeostasis and visual function decline | 000 | 1 | NIH | 6/26/2024 | $745,418 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DK128435 | The B Cell Insulin Receptor in Health and in Insulin Resistance | 000 | 3 | NIH | 12/5/2023 | $509,506 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DK128435 | The B Cell Insulin Receptor in Health and in Insulin Resistance | 001 | 3 | NIH | 5/6/2024 | $33,966 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R21AR084303 | Spatial Proteomics of osteoarthritis in bones to uncover disease progression | 000 | 1 | NIH | 9/18/2024 | $456,808 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG081226 | TAKEOFF: Targeting Aging with Ketone Ester in Older adults for Function in Frailty | 002 | 2 | NIH | 9/24/2024 | $0 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG076933 | Investigation of impaired neural stem cell activation in Alzheimer's Disease | 004 | 3 | NIH | 6/26/2024 | $523,818 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG081989 | A smart cell drug (SmaCD) delivery platform for mobile, targetable, and self-regulated combination therapy: a model project to rescue antibodies from Alzheimer's disease (AD) clinical trial failures | 001 | 3 | NIH | 6/27/2024 | $476,782 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U01AG086214 | Identifying Organ-Specific Blood Biomarkers of Aging and Assessing their Effects on Cardiovascular Health | 000 | 1 | NIH | 6/13/2024 | $700,310 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P01AG066591 | Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementias | 008 | 4 | NIH | 6/13/2024 | $65,114 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P01AG066591 | Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementias | 007 | 4 | NIH | 6/12/2024 | $27,841 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068296 | Cellular senescence and Alzheimer's disease | 000 | 2 | NIH | 7/26/2024 | $467,034 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG082824 | Novel mitochondria-to-lysosome crosstalk contributes to lysosomal dysfunction during aging | 000 | 2 | NIH | 7/26/2024 | $485,000 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG067326 | Targeting Aging to prevent Alzheimer's Disease: the Geroscience Approach | 001 | 5 | NIH | 6/25/2024 | $58,187 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG070193 | Impaired activity-dependent protein synthesis in dendrites and pathophysiology in tauopathy | 001 | 4 | NIH | 7/23/2024 | $0 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P01AG066591 | Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementias | 009 | 4 | NIH | 6/17/2024 | $502,928 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG070193 | Impaired activity-dependent protein synthesis in dendrites and pathophysiology in tauopathy | 000 | 4 | NIH | 7/16/2024 | $785,399 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG081226 | TAKEOFF: Targeting Aging with Ketone Ester in Older adults for Function in Frailty | 001 | 2 | NIH | 8/19/2024 | $702,825 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG067325 | Neuronal FXR as a potential therapeutic target for Alzheimer's disease | 000 | 5 | NIH | 4/17/2024 | $625,485 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01NS100529 | Identifying Factors Regulating Medium Spiny Neuron Differentiation or Maintenance as Therapeutic Targets for Huntington's Disease using Induced Pluripotent Stem Cells | 001 | 6 | NIH | 5/3/2024 | $809,186 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG076933 | Investigation of impaired neural stem cell activation in Alzheimer's Disease | 001 | 3 | NIH | 6/5/2024 | $462,646 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG073411 | Pioneer transcription factors in aging and neurodegeneration | 005 | 5 | NIH | 5/13/2024 | $568,692 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P01AG066591 | Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementias | 006 | 4 | NIH | 6/4/2024 | $115,399 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P01AG066591 | Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementias | 005 | 4 | NIH | 6/4/2024 | -$92,955 |
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