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 | Issue Date FY: 2023 ( Subtotal = $17,576,477 ) (Continued on the next page) |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG061165 | Advanced glycation endproducts (AGEs) as metabolic by-products that mediate neurodegeneration. | 000 | 5 | NIH | 5/10/2023 | $646,911 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG082824 | Novel mitochondria-to-lysosome crosstalk contributes to lysosomal dysfunction during aging | 000 | 1 | NIH | 7/25/2023 | $485,000 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | UH3CA268105 | Evaluating diverse technologies for detecting and validating senescent cells in vivo | 000 | 3 | NIH | 8/28/2023 | $909,684 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG081989 | A smart cell drug (SmaCD) delivery platform for mobile, targetable, and self-regulated combination therapy: a model project to rescue antibodies from Alzheimer's disease (AD) clinical trial failures | 000 | 2 | NIH | 6/22/2023 | $486,610 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R13AG082490 | The Reproductive Aging Conference | 000 | 1 | NIH | 4/11/2023 | $49,000 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DK128435 | The B Cell Insulin Receptor in Health and in Insulin Resistance | 003 | 2 | NIH | 3/2/2023 | $0 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U54AG075932 | Senescent cell mapping, identification and validation for human somatic and reproductive tissues | 001 | 3 | NIH | 7/28/2023 | $2,237,050 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P01AG066591 | Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementias | 003 | 3 | NIH | 7/11/2023 | $112,210 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P01AG066591 | Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementias | 002 | 3 | NIH | 6/9/2023 | $111,434 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P01AG066591 | Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementias | 001 | 3 | NIH | 6/8/2023 | $2,878,430 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U01AG045844 | Caenorhabditis Intervention Testing Program - Buck Institute | 002 | 10 | NIH | 8/1/2023 | $719,371 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG038664 | Regulation of the Autophagy Pathway with Age and in Long-lived Animals | 000 | 12 | NIH | 1/5/2023 | $618,179 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P01AG066591 | Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementias | 000 | 2 | NIH | 12/26/2022 | $46,513 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG070193 | Impaired activity-dependent protein synthesis in dendrites and pathophysiology in tauopathy | 000 | 3 | NIH | 7/25/2023 | $784,070 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P30AG068345 | The University of Southern California and Buck Institute Nathan Shock Center | 001 | 4 | NIH | 6/7/2023 | $923,307 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | T32AG000266 | Training in Basic Research on Aging and Age-Related Disease | 001 | 25 | NIH | 5/1/2023 | $785,981 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068025 | Geroscience metabolites beta-hydroxybutyrate and NAD+ linking inflammation and neuroenergetic failure in delirium | 002 | 4 | NIH | 4/27/2023 | $769,087 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068288 | Methylglyoxal drives astrocyte senescence to mediate neurodegeneration in Alzheimer's disease | 003 | 4 | NIH | 8/31/2023 | -$115,399 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | K01AG078125 | Exogenous ketones target geroscience pathways and ameliorate geriatric syndromes | 001 | 2 | NIH | 7/7/2023 | $175,451 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068288 | Methylglyoxal drives astrocyte senescence to mediate neurodegeneration in Alzheimer's disease | 000 | 4 | NIH | 7/25/2023 | $485,000 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG067333 | Mechanisms of the signaling metabolite ?-hydroxybutyrate in Alzheimer's disease and the aging brain | 001 | 4 | NIH | 7/11/2023 | $45,072 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068288 | Methylglyoxal drives astrocyte senescence to mediate neurodegeneration in Alzheimer's disease | 001 | 4 | NIH | 7/28/2023 | $115,399 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG067333 | Mechanisms of the signaling metabolite ?-hydroxybutyrate in Alzheimer's disease and the aging brain | 000 | 4 | NIH | 7/7/2023 | $758,000 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG075201 | Multidimensional mapping of proteome changes and mechanisms underlying yeast replicative aging | 000 | 2 | NIH | 3/28/2023 | $558,796 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068288 | Methylglyoxal drives astrocyte senescence to mediate neurodegeneration in Alzheimer's disease | 002 | 4 | NIH | 8/30/2023 | $9,287 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG067325 | Neuronal FXR as a potential therapeutic target for Alzheimer's disease | 000 | 4 | NIH | 3/24/2023 | $624,323 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG067326 | Targeting Aging to prevent Alzheimer's Disease: the Geroscience Approach | 001 | 4 | NIH | 4/18/2023 | $0 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R35GM145305 | Cellular and Circuit Mechanisms of Neuropeptide Signaling | 000 | 2 | NIH | 5/17/2023 | $485,000 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DK128435 | The B Cell Insulin Receptor in Health and in Insulin Resistance | 001 | 2 | NIH | 1/31/2023 | $56,584 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068288 | Methylglyoxal drives astrocyte senescence to mediate neurodegeneration in Alzheimer's disease | 003 | 4 | NIH | 8/31/2023 | $115,399 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG067326 | Targeting Aging to prevent Alzheimer's Disease: the Geroscience Approach | 000 | 4 | NIH | 4/4/2023 | $581,874 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG081226 | TAKEOFF: Targeting Aging with Ketone Ester in Older adults for Function in Frailty | 000 | 1 | NIH | 8/16/2023 | $755,249 |
| | 2023 | 2023 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DK128435 | The B Cell Insulin Receptor in Health and in Insulin Resistance | 000 | 2 | NIH | 12/7/2022 | $509,277 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U01AG060906 | Quantitative Proteomics to Develop Robust Senescence-Related Biomarkers for Aging | 000 | 5 | NIH | 11/25/2022 | $0 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DK128435 | The B Cell Insulin Receptor in Health and in Insulin Resistance | 002 | 1 | NIH | 3/2/2023 | $0 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | RF1AG062280 | New mechanistic insights into how the gut metabolite urolithin A extends lifespan and prevents AD | 001 | 1 | NIH | 10/25/2022 | $0 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | UG3CA268105 | Evaluating diverse technologies for detecting and validating senescent cells in vivo | 000 | 2 | NIH | 1/27/2023 | $0 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U54AG075932 | Senescent cell mapping, identification and validation for human somatic and reproductive tissues | 000 | 2 | NIH | 3/16/2023 | $0 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U01AG045844 | Caenorhabditis Intervention Testing Program - Buck Institute | 001 | 8 | NIH | 7/10/2023 | -$97,402 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U01AG045844 | Caenorhabditis Intervention Testing Program - Buck Institute | 000 | 9 | NIH | 7/10/2023 | $97,402 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG072791 | Role of Selective Autophagy in Organismal Health | 000 | 2 | NIH | 6/9/2023 | $0 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | T32AG000266 | Training in Basic Research on Aging and Age-Related Disease | 000 | 24 | NIH | 11/22/2022 | $0 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P30AG068345 | The University of Southern California and Buck Institute Nathan Shock Center | 000 | 3 | NIH | 11/14/2022 | $0 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068025 | Geroscience metabolites beta-hydroxybutyrate and NAD+ linking inflammation and neuroenergetic failure in delirium | 000 | 2 | NIH | 1/31/2023 | -$7,440 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068025 | Geroscience metabolites beta-hydroxybutyrate and NAD+ linking inflammation and neuroenergetic failure in delirium | 001 | 3 | NIH | 1/31/2023 | -$38,329 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | K01AG078125 | Exogenous ketones target geroscience pathways and ameliorate geriatric syndromes | 000 | 1 | NIH | 1/20/2023 | $0 |
| | 2023 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | F32AG063488 | Functional mapping of thirst circuits in the aging mouse brain | 000 | 3 | NIH | 5/15/2023 | -$7,950 |
| | 2023 | 2021 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R35GM119828 | Cellular and Circuit Mechanisms of Neuropeptide Signaling | 000 | 5 | NIH | 11/13/2022 | -$8,264 |
| | 2023 | 2021 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DA041742 | Molecular Mechanisms of HIV Latency | 000 | 6 | NIH | 6/12/2023 | $0 |
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