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 | Issue Date FY: 2025 ( Subtotal = $46,546,229 ) |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | AY2AX000072 | Personalized Analytics for Transforming Healthcare (PATH) | 000 | 1 | NIH | 10/23/2024 | $9,600,740 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DK135807 | Novel components of mitochondrial regulation of insulin secretion in type 2 diabetes | 000 | 2 | NIH | 12/9/2024 | $603,283 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DK128435 | The B Cell Insulin Receptor in Health and in Insulin Resistance | 000 | 4 | NIH | 11/25/2024 | $509,712 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG072791 | Role of Selective Autophagy in Organismal Health | 000 | 4 | NIH | 5/8/2025 | $439,484 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R13AG059431 | Summer Training Course in Experimental Aging | 002 | 7 | NIH | 5/12/2025 | $54,068 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R13AG059431 | Summer Training Course in Experimental Aging | 000 | 7 | NIH | 4/29/2025 | $101,085 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01NS100529 | Identifying Factors Regulating Medium Spiny Neuron Differentiation or Maintenance as Therapeutic Targets for Huntington's Disease using Induced Pluripotent Stem Cells | 000 | 7 | NIH | 5/14/2025 | $785,686 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG038664 | Regulation of the Autophagy Pathway with Age and in Long-lived Animals | 000 | 13 | NIH | 12/10/2024 | $575,400 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | S10OD038264 | timsTOF fleX MALDI-2 for Spatial Molecular Imaging | 000 | 1 | NIH | 3/25/2025 | $1,759,412 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG076933 | Investigation of impaired neural stem cell activation in Alzheimer's Disease | 000 | 4 | NIH | 3/14/2025 | $433,733 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | AY2AX000072 | Personalized Analytics for Transforming Healthcare (PATH) | 002 | 1 | NIH | 1/8/2025 | $29,741,025 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | AY2AX000072 | Personalized Analytics for Transforming Healthcare (PATH) | 001 | 1 | NIH | 10/30/2024 | $9,600,740 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | AY2AX000072 | Personalized Analytics for Transforming Healthcare (PATH) | 001 | 1 | NIH | 10/30/2024 | -$9,600,740 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U01AI180158 | Cellular senescence and Associated Lysosomal Dysfunction in Immune Aging | 000 | 2 | NIH | 2/13/2025 | $671,861 |
| | 2025 | 2025 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U01AG086214 | Identifying Organ-Specific Blood Biomarkers of Aging and Assessing their Effects on Cardiovascular Health | 000 | 2 | NIH | 3/18/2025 | $645,948 |
| | 2025 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P30AG068345 | The University of Southern California and Buck Institute Nathan Shock Center | 000 | 5 | NIH | 3/25/2025 | $0 |
| | 2025 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | T32AG000266 | Training in Basic Research on Aging and Age-Related Disease | 000 | 26 | NIH | 4/22/2025 | $0 |
| | 2025 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R35GM145305 | Cellular and Circuit Mechanisms of Neuropeptide Signaling | 000 | 3 | NIH | 12/6/2024 | $0 |
| | 2025 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068296 | Cellular senescence and Alzheimer's disease | 000 | 2 | NIH | 3/12/2025 | $31,860 |
| | 2025 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U54AG075932 | Senescent cell mapping, identification and validation for human somatic and reproductive tissues | 000 | 4 | NIH | 2/14/2025 | $0 |
| | 2025 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | RF1AG053268 | Molecular mechanisms underlying the preservation of neural stem cell quiescence during aging | 001 | 7 | NIH | 2/19/2025 | $142,419 |
| | 2025 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | RF1AG053268 | Molecular mechanisms underlying the preservation of neural stem cell quiescence during aging | 001 | 7 | NIH | 2/19/2025 | $169,852 |
| | 2025 | 2022 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | RF1AG053268 | Molecular mechanisms underlying the preservation of neural stem cell quiescence during aging | 001 | 7 | NIH | 2/19/2025 | $350,591 |
| | 2025 | 2021 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DA041742 | Molecular Mechanisms of HIV Latency | 001 | 6 | NIH | 11/12/2024 | -$5,363 |
| | 2025 | 2021 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DA041742 | Molecular Mechanisms of HIV Latency | 000 | 6 | NIH | 11/12/2024 | -$32,707 |
| | 2025 | 2020 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | RF1AG068296 | Cellular senescence and Alzheimer's disease | 000 | 1 | NIH | 3/12/2025 | -$31,860 |
|
| Issue Date FY: 2024 ( Subtotal = $26,618,426 ) (Continued on the next page) |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068025 | Geroscience metabolites beta-hydroxybutyrate and NAD+ linking inflammation and neuroenergetic failure in delirium | 000 | 4 | NIH | 10/26/2023 | $67,316 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U01AI180158 | Cellular senescence and Associated Lysosomal Dysfunction in Immune Aging | 001 | 1 | NIH | 9/19/2024 | $0 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U01AI180158 | Cellular senescence and Associated Lysosomal Dysfunction in Immune Aging | 000 | 1 | NIH | 2/26/2024 | $692,640 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG068296 | Cellular senescence and Alzheimer's disease | 000 | 2 | NIH | 7/26/2024 | $467,034 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U01AG086214 | Identifying Organ-Specific Blood Biomarkers of Aging and Assessing their Effects on Cardiovascular Health | 000 | 1 | NIH | 6/13/2024 | $700,310 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DK135807 | Novel components of mitochondrial regulation of insulin secretion in type 2 diabetes | 000 | 1 | NIH | 12/8/2023 | $670,313 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R21AR084303 | Spatial Proteomics of osteoarthritis in bones to uncover disease progression | 000 | 1 | NIH | 9/18/2024 | $456,808 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R25AG086096 | Support and Preparation for an Alzheimer's Research Career | 000 | 1 | NIH | 5/20/2024 | $432,000 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG082824 | Novel mitochondria-to-lysosome crosstalk contributes to lysosomal dysfunction during aging | 000 | 2 | NIH | 7/26/2024 | $485,000 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DK128435 | The B Cell Insulin Receptor in Health and in Insulin Resistance | 001 | 3 | NIH | 5/6/2024 | $33,966 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01DK128435 | The B Cell Insulin Receptor in Health and in Insulin Resistance | 000 | 3 | NIH | 12/5/2023 | $509,506 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | UH3CA268105 | Evaluating diverse technologies for detecting and validating senescent cells in vivo | 002 | 4 | NIH | 8/28/2024 | $909,684 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | K01AG078125 | Exogenous ketones target geroscience pathways and ameliorate geriatric syndromes | 000 | 3 | NIH | 5/28/2024 | $175,144 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG081226 | TAKEOFF: Targeting Aging with Ketone Ester in Older adults for Function in Frailty | 002 | 2 | NIH | 9/24/2024 | $0 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG081226 | TAKEOFF: Targeting Aging with Ketone Ester in Older adults for Function in Frailty | 001 | 2 | NIH | 8/19/2024 | $702,825 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R13AG082490 | The Reproductive Aging Conference | 000 | 2 | NIH | 3/20/2024 | $49,000 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | U54AG075932 | Senescent cell mapping, identification and validation for human somatic and reproductive tissues | 002 | 4 | NIH | 8/23/2024 | $2,390,550 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG067326 | Targeting Aging to prevent Alzheimer's Disease: the Geroscience Approach | 001 | 5 | NIH | 6/25/2024 | $58,187 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG067326 | Targeting Aging to prevent Alzheimer's Disease: the Geroscience Approach | 000 | 5 | NIH | 3/1/2024 | $523,687 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | R01AG072791 | Role of Selective Autophagy in Organismal Health | 000 | 3 | NIH | 4/24/2024 | $526,081 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P01AG066591 | Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementias | 008 | 4 | NIH | 6/13/2024 | $65,114 |
| | 2024 | 2024 | BUCK INSTITUTE FOR RESEARCH ON AGING | 8001 REDWOOD BLVD | NOVATO | CA | 94945-1400 | MARIN | USA | P01AG066591 | Cellular senescence and cell fate/interactions as drivers of Alzheimer's and age-related dementias | 007 | 4 | NIH | 6/12/2024 | $27,841 |
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