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 | Issue Date FY: 2024 ( Subtotal = $510,542 ) |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32AI181510 | Investigating differentiation, maintenance, and reactivation of the Toxoplasma chronic stage | 000 | 1 | NIH | 11/28/2023 | $71,792 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01AI144369 | Control of parasite invasion by a microneme protein complex conserved in Apicomplexans | 000 | 5 | NIH | 11/22/2023 | $438,750 |
| | 2024 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | RM1HG009490 | Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease | 000 | 7 | NIH | 11/13/2023 | $0 |
|
| Issue Date FY: 2023 ( Subtotal = $10,849,878 ) |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35CA220487 | Epi-genetic Programs in Cancer Progression | 000 | 7 | NIH | 8/7/2023 | $1,146,600 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM145321 | Function and Mechanisms of Epigenetic Stability and Dynamics in Arabidopsis | 000 | 2 | NIH | 7/18/2023 | $487,500 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM144283 | Transcriptional regulation in mammalian cells | 000 | 2 | NIH | 5/23/2023 | $798,507 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | RM1HG009490 | Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease | 006 | 7 | NIH | 6/2/2023 | $2,500,000 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K00CA253729 | Tumor and Immune Cell Dynamics during Immunotherapy and Cancer Progression | 000 | 4 | NIH | 8/24/2023 | $100,486 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32GM143850 | Reprogramming towards a germline stem cell fate | 000 | 3 | NIH | 8/23/2023 | $71,792 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01AI158501 | Development and maintenance of chronic toxoplasmosis | 000 | 3 | NIH | 2/9/2023 | $659,753 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32GM140745 | Mechanisms of mitochondrial inheritance - Pamula Admin Childcare Supplement | 000 | 2 | NIH | 12/26/2022 | $2,500 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM118135 | Post-transcriptional gene regulation | 000 | 8 | NIH | 4/13/2023 | $734,329 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K00CA234921 | The role of lysosomal deregulation in cancer progression | 000 | 6 | NIH | 7/13/2023 | $105,985 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01MH104610 | Transcriptional condensates, epigenetic editing and Rett Syndrome | 000 | 24 | NIH | 7/21/2023 | $881,324 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01AI144369 | Control of parasite invasion by a microneme protein complex conserved in Apicomplexans | 000 | 4 | NIH | 11/8/2022 | $487,500 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01HD110546 | Protecting and Sustaining Germ Cell Identity | 000 | 1 | NIH | 8/11/2023 | $419,250 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K99GM151487 | Genetic and biophysical analysis of morphogen gradient formation | 000 | 1 | NIH | 8/11/2023 | $125,000 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01CA279259 | KRAS inhibitors prime cancer cells for macrophage-mediated destruction | 000 | 1 | NIH | 5/19/2023 | $446,063 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM151111 | Elucidating the molecular and cellular functions of polyamines | 000 | 1 | NIH | 8/22/2023 | $487,500 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM126930 | Molecular Analysis of Kinetochore Function | 000 | 6 | NIH | 4/27/2023 | $793,650 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K99HG012887 | Predictive modeling of mammalian cell fate transitions over time and space with single-cell genomics | 000 | 1 | NIH | 1/27/2023 | $122,138 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32GM150241 | Deciphering Translational Control in Stem Cells | 001 | 1 | NIH | 3/17/2023 | $0 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32GM150241 | Deciphering Translational Control in Stem Cells | 000 | 1 | NIH | 3/17/2023 | $69,500 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32HD111257 | Maternal organelle contribution to offspring germline health | 000 | 1 | NIH | 1/2/2023 | $66,790 |
| | 2023 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM145345 | Stem cell and regeneration regulatory mechanisms in planarians | 000 | 2 | NIH | 6/30/2023 | $487,500 |
| | 2023 | 2022 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | RM1HG009490 | Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease | 003 | 6 | NIH | 1/17/2023 | -$925 |
| | 2023 | 2022 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K99CA255926 | Mechanistic insights into lysosomal nutrient efflux in cancer | 000 | 2 | NIH | 6/15/2023 | -$78,080 |
| | 2023 | 2022 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K99HD097285 | Establishment of the meiotic cell cycle program through post-transcriptional regulation by MEIOC and YTHDC2 | 000 | 2 | NIH | 8/7/2023 | -$5,689 |
| | 2023 | 2022 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K00CA234839 | Metabolic Recycling and Compartmentalization in Tumor Progression | 000 | 5 | NIH | 11/9/2022 | -$59,261 |
| | 2023 | 2022 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | RM1HG009490 | Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease | 001 | 6 | NIH | 11/17/2022 | $925 |
| | 2023 | 2022 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | RM1HG009490 | Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease | 005 | 6 | NIH | 1/20/2023 | $925 |
| | 2023 | 2021 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01AI047389 | Novel Components of the mTORC1 and mTORC2 Pathways | 000 | 22 | NIH | 6/22/2023 | $0 |
| | 2023 | 2021 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R00HD087532 | Spatio-Temporal Signaling Dynamics in Neuronal Cell Fate Decision and Patterning | 000 | 5 | NIH | 7/7/2023 | $0 |
| | 2023 | 2021 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32AG060695 | Human induced pluripotent stem cell modeling of genetic risk factors for Alzheimer's disease | 002 | 3 | NIH | 1/19/2023 | $0 |
| | 2023 | 2021 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32AG059361 | Using Mitochondrial DNA Mutations to Understand Limitations of Mitochondrial Quality Control | 000 | 3 | NIH | 5/15/2023 | $0 |
| | 2023 | 2021 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01CA219859 | Exploiting mitochondrial heteroplasmy for cancer chemotherapy | 000 | 5 | NIH | 4/11/2023 | $0 |
| | 2023 | 2021 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | S10OD028520 | Zeiss LSM 980 with Airyscan 2 confocal microscope system | 000 | 1 | NIH | 1/31/2023 | $0 |
| | 2023 | 2020 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01GM080639 | Stem cell and regeneration regulatory genes in planarians | 000 | 13 | NIH | 10/30/2022 | -$1,684 |
| | 2023 | 2020 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K99HD099315 | Molecular control of oocyte arrest, meiosis, and the transition to development | 000 | 2 | NIH | 7/10/2023 | $0 |
| | 2023 | 2020 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R00AG053434 | RNA Gelation in Repeat Expansion Disorders | 000 | 5 | NIH | 11/23/2022 | $0 |
| | 2023 | 2020 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32AG060695 | Human induced pluripotent stem cell modeling of genetic risk factors for Alzheimer's disease | 001 | 2 | NIH | 1/19/2023 | $0 |
| | 2023 | 2020 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01GM123511 | Transcriptional regulatory networks in living cells | 000 | 17 | NIH | 1/10/2023 | $0 |
| | 2023 | 2018 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32AG060695 | Human induced pluripotent stem cell modeling of genetic risk factors for Alzheimer's disease | 000 | 1 | NIH | 1/19/2023 | $0 |
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| Issue Date FY: 2022 ( Subtotal = $11,230,338 ) (Continued on the next page) |
| | 2022 | 2022 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM118135 | Post-transcriptional gene regulation | 000 | 7 | NIH | 4/15/2022 | $660,896 |
| | 2022 | 2022 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32GM143850 | Reprogramming towards a germline stem cell fate | 000 | 2 | NIH | 8/12/2022 | $67,582 |
| | 2022 | 2022 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32GM140745 | Mechanisms of mitochondrial inheritance - Pamula Admin Childcare Supplement | 000 | 2 | NIH | 6/17/2022 | $69,802 |
| | 2022 | 2022 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM144283 | Transcriptional regulation in mammalian cells | 000 | 1 | NIH | 7/20/2022 | $798,507 |
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