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 | Issue Date FY: 2025 ( Subtotal = $3,034,426 ) |
| | 2025 | 2025 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K99HD118574 | Spatially-resolved, integrated cell state and lineage tracing to define progenitor cell dynamics in early mouse development | 000 | 1 | NIH | 2/20/2025 | $125,000 |
| | 2025 | 2025 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01HD110546 | Protecting and Sustaining Germ Cell Identity | 000 | 3 | NIH | 4/15/2025 | $419,250 |
| | 2025 | 2025 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM126930 | Molecular Analysis of Kinetochore Function | 001 | 8 | NIH | 4/4/2025 | $793,650 |
| | 2025 | 2025 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM118135 | Post-transcriptional gene regulation | 001 | 10 | NIH | 4/8/2025 | $734,329 |
| | 2025 | 2025 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32HD111257 | Maternal organelle contribution to offspring germline health | 000 | 3 | NIH | 1/13/2025 | $74,284 |
| | 2025 | 2025 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K99GM154143 | Combinatorial signal integration in the maintenance and renewal of adult germline stem cell fate | 000 | 1 | NIH | 12/16/2024 | $125,000 |
| | 2025 | 2025 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32AI181510 | Investigating differentiation, maintenance, and reactivation of the Toxoplasma chronic stage | 000 | 2 | NIH | 4/18/2025 | $78,892 |
| | 2025 | 2025 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32MH134541 | Mechanisms governing post-transcriptional regulation of neuronal microRNAs | 000 | 2 | NIH | 4/16/2025 | $78,892 |
| | 2025 | 2025 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01AI158501 | Development and maintenance of chronic toxoplasmosis | 000 | 5 | NIH | 2/18/2025 | $607,619 |
| | 2025 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM144283 | Transcriptional regulation in mammalian cells | 000 | 3 | NIH | 12/6/2024 | $0 |
| | 2025 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM145345 | Stem cell and regeneration regulatory mechanisms in planarians | 000 | 3 | NIH | 12/6/2024 | $0 |
| | 2025 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM126930 | Molecular Analysis of Kinetochore Function | 000 | 7 | NIH | 11/6/2024 | $0 |
| | 2025 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM118135 | Post-transcriptional gene regulation | 000 | 9 | NIH | 11/6/2024 | $0 |
| | 2025 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM145321 | Function and Mechanisms of Epigenetic Stability and Dynamics in Arabidopsis | 000 | 3 | NIH | 11/13/2024 | $0 |
| | 2025 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | DP2HD108777 | Systematic Reconstruction of Epithelial-Mesenchymal Communication in Organ Development | 001 | 2 | NIH | 10/10/2024 | $591,113 |
| | 2025 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K99HD113821 | Uncovering the Mechanisms that Promote and Maintain Germ Cell Identity | 000 | 1 | NIH | 2/17/2025 | $0 |
| | 2025 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K00CA234921 | The role of lysosomal deregulation in cancer progression | 000 | 6 | NIH | 12/4/2024 | -$2,490 |
| | 2025 | 2023 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35CA220487 | Epi-genetic Programs in Cancer Progression | 000 | 7 | NIH | 3/12/2025 | $0 |
| | 2025 | 2021 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | DP2HD108777 | Systematic Reconstruction of Epithelial-Mesenchymal Communication in Organ Development | 000 | 1 | NIH | 10/10/2024 | -$591,113 |
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| Issue Date FY: 2024 ( Subtotal = $10,810,103 ) (Continued on the next page) |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01AI158501 | Development and maintenance of chronic toxoplasmosis | 001 | 4 | NIH | 5/24/2024 | $64,289 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K99HD115278 | The world’s smallest vertebrate brain: A new model for nervous system function and regeneration research | 000 | 1 | NIH | 6/28/2024 | $135,864 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K99GM151487 | Genetic and biophysical analysis of morphogen gradient formation | 000 | 2 | NIH | 8/19/2024 | $125,000 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01CA279259 | KRAS inhibitors prime cancer cells for macrophage-mediated destruction | 000 | 2 | NIH | 5/14/2024 | $423,760 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM145345 | Stem cell and regeneration regulatory mechanisms in planarians | 000 | 3 | NIH | 6/24/2024 | $487,500 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01HD110546 | Protecting and Sustaining Germ Cell Identity | 000 | 2 | NIH | 5/6/2024 | $415,058 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM144283 | Transcriptional regulation in mammalian cells | 000 | 3 | NIH | 5/23/2024 | $798,507 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32HD111257 | Maternal organelle contribution to offspring germline health | 001 | 2 | NIH | 5/6/2024 | $6,654 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32HD111257 | Maternal organelle contribution to offspring germline health | 000 | 2 | NIH | 12/21/2023 | $67,174 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K00CA284259 | Mechanisms of gene expression regulation in pancreatic cancer | 000 | 3 | NIH | 8/26/2024 | $103,639 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | DP5OD037342 | Leveraging cell-derived bioparticles for macromolecular delivery | 000 | 1 | NIH | 9/18/2024 | $1 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | DP5OD037342 | Leveraging cell-derived bioparticles for macromolecular delivery | 000 | 1 | NIH | 9/18/2024 | $487,499 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K00CA284289 | Chromatin and immune regulation of tumor growth and progression | 001 | 2 | NIH | 9/4/2024 | $103,497 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K00CA284289 | Chromatin and immune regulation of tumor growth and progression | 001 | 2 | NIH | 9/4/2024 | -$103,497 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K00CA284289 | Chromatin and immune regulation of tumor growth and progression | 000 | 2 | NIH | 8/21/2024 | $103,497 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K00CA253729 | Tumor and Immune Cell Dynamics during Immunotherapy and Cancer Progression | 000 | 5 | NIH | 8/20/2024 | $112,022 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | K99HD113821 | Uncovering the Mechanisms that Promote and Maintain Germ Cell Identity | 000 | 1 | NIH | 9/13/2024 | $135,864 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01AI144369 | Control of parasite invasion by a microneme protein complex conserved in Apicomplexans | 001 | 5 | NIH | 5/16/2024 | $48,750 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R01AI144369 | Control of parasite invasion by a microneme protein complex conserved in Apicomplexans | 000 | 5 | NIH | 11/22/2023 | $438,750 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM126930 | Molecular Analysis of Kinetochore Function | 003 | 7 | NIH | 6/26/2024 | $79,365 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM126930 | Molecular Analysis of Kinetochore Function | 002 | 7 | NIH | 4/16/2024 | $714,285 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM118135 | Post-transcriptional gene regulation | 001 | 9 | NIH | 7/17/2024 | $73,433 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM118135 | Post-transcriptional gene regulation | 000 | 9 | NIH | 4/1/2024 | $660,896 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | RM1HG009490 | Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease | 001 | 8 | NIH | 6/21/2024 | $2,449,998 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | RM1HG009490 | Center for Genomic Editing and Recording: Development and Application of Next-Generation Genome and Epigenome Editing Methods to Advance the Study and Treatment of Human Disease | 002 | 8 | NIH | 8/28/2024 | $0 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32AI181510 | Investigating differentiation, maintenance, and reactivation of the Toxoplasma chronic stage | 002 | 1 | NIH | 5/8/2024 | $4,964 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32AI181510 | Investigating differentiation, maintenance, and reactivation of the Toxoplasma chronic stage | 001 | 1 | NIH | 11/28/2023 | $0 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | F32AI181510 | Investigating differentiation, maintenance, and reactivation of the Toxoplasma chronic stage | 000 | 1 | NIH | 11/28/2023 | $71,792 |
| | 2024 | 2024 | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH | 455 MAIN ST | CAMBRIDGE | MA | 02142-1025 | MIDDLESEX | USA | R35GM145321 | Function and Mechanisms of Epigenetic Stability and Dynamics in Arabidopsis | 000 | 3 | NIH | 7/16/2024 | $487,500 |
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