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 | Issue Date FY: 2025 ( Subtotal = $12,620,048 ) |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01DK134652 | Role of trefoil factor family proteins in beta cell function. | 000 | 3 | NIH | 11/13/2024 | $511,289 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA286160 | Targeting Immune Escape in CML/MPN Transformation | 001 | 2 | NIH | 11/20/2024 | $514,454 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA258778 | Targeting tumor-associated macrophages for triple-negative breast cancer treatment | 000 | 4 | NIH | 11/12/2024 | $467,633 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA241845 | Validation of epigenomic biomarkers for thyroid cancer diagnostics | 000 | 4 | NIH | 11/13/2024 | $737,207 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA258981 | The Role of miR-142 in the Transformation of Clonal Hematopoietic Disorders into AML | 001 | 4 | NIH | 12/19/2024 | $488,601 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA279595 | Targeting Protein Arginine Methyltransferases to Eradicate Acute Myeloid Leukemia | 000 | 2 | NIH | 11/19/2024 | $637,252 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA296280 | CMV-specific CD19 CAR T cells amplified in vivo using CMV Triplex vaccine for B-NHL | 001 | 1 | NIH | 12/4/2024 | $0 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA296280 | CMV-specific CD19 CAR T cells amplified in vivo using CMV Triplex vaccine for B-NHL | 000 | 1 | NIH | 11/27/2024 | $738,698 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | K01DK128387 | The role of Nrf2 in beta cell expansion during pregnancy | 001 | 4 | NIH | 12/6/2024 | $153,554 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA296394 | Targeting mitochondrial RNA methylation in high-risk acute myeloid leukemia | 000 | 1 | NIH | 12/10/2024 | $487,542 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA283171 | Attacking the Tumor Cell-Immune Milieu Interface to Overcome Richter's Transformation | 000 | 1 | NIH | 12/16/2024 | $721,723 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA266665 | Engineered anti-PSCA antibodies for immunoPET and targeted therapy of pancreatic cancer | 000 | 4 | NIH | 12/19/2024 | $540,806 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01HL162847 | Pathogenesis, prevention and treatment of corticosteroid-resistant gut GVHD | 000 | 3 | NIH | 12/20/2024 | $771,055 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | P30CA033572 | Cancer Center Support Grant | 001 | 42 | NIH | 12/23/2024 | $199,548 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | P30CA033572 | Cancer Center Support Grant | 002 | 42 | NIH | 12/26/2024 | $249,999 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | P30CA033572 | Cancer Center Support Grant | 000 | 42 | NIH | 12/20/2024 | $3,536,183 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01DK138665 | Targeting bile acid composition to treat metabolic diseases | 000 | 2 | NIH | 12/31/2024 | $599,308 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA278050 | Mechanism and therapeutic opportunities of targeting the Tudor domain | 000 | 3 | NIH | 11/20/2024 | $460,155 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R25CA217270 | Preparing Oncology Advanced Practice Nurses as Generalists in Palliative Care | 000 | 8 | NIH | 1/10/2025 | $291,600 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R37CA233691 | Combinational Targeting the Feed-forward Epigenetic Circuitry in Mixed Lineage Leukemia | 000 | 7 | NIH | 12/12/2024 | $362,340 |
| | 2025 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | UM1CA186717 | Phase 1 and 2 Molecular and Clinical Pharmacodynamic Trials ETCTN | 000 | 8 | NIH | 12/31/2024 | $0 |
| | 2025 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01NS134116 | Improving Glioma Immunotherapy Efficacy by Regulating Tumor Inflammation | 002 | 2 | NIH | 11/26/2024 | $2,634 |
| | 2025 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01NS134116 | Improving Glioma Immunotherapy Efficacy by Regulating Tumor Inflammation | 001 | 2 | NIH | 11/21/2024 | $0 |
| | 2025 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01NS134116 | Improving Glioma Immunotherapy Efficacy by Regulating Tumor Inflammation | 000 | 2 | NIH | 10/24/2024 | $0 |
| | 2025 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA247550 | Characterizing and Targeting the Novel IL-15- AKT-XBP1s Pathway in NK Cells | 000 | 5 | NIH | 10/18/2024 | -$171,933 |
| | 2025 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA286160 | Targeting Immune Escape in CML/MPN Transformation | 000 | 1 | NIH | 10/30/2024 | $0 |
| | 2025 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA258981 | The Role of miR-142 in the Transformation of Clonal Hematopoietic Disorders into AML | 000 | 3 | NIH | 11/8/2024 | $0 |
| | 2025 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01AI152068 | BCL11B activation as an approach for enhancing the efficacy of immunotherapy | 001 | 5 | NIH | 11/25/2024 | $320,400 |
| | 2025 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01AI152068 | BCL11B activation as an approach for enhancing the efficacy of immunotherapy | 002 | 5 | NIH | 12/5/2024 | $0 |
| | 2025 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R25CA240111 | Interdisciplinary Communication Training in Oncology | 000 | 5 | NIH | 11/27/2024 | $0 |
| | 2025 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA264911 | Unmasking the roles of viral glycoproteins in oral transmission of KSHV | 000 | 4 | NIH | 12/20/2024 | $0 |
| | 2025 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | U24DK104162 | Renewal of the Human Islet Research Enhancement Center (HIREC) for the Type-1-Diabetes-Focused Human Islet Research Network (HIRN). | 000 | 11 | NIH | 10/23/2024 | $0 |
| | 2025 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | U24DK104162 | Renewal of the Human Islet Research Enhancement Center (HIREC) for the Type-1-Diabetes-Focused Human Islet Research Network (HIRN). | 000 | 11 | NIH | 10/23/2024 | $0 |
| | 2025 | 2023 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA242218 | Precision approaches to refining TP53-associated cancer risk | 000 | 5 | NIH | 12/23/2024 | $0 |
| | 2025 | 2023 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01NS106170 | Overcoming Barriers of Virotherapy by Next-Generation oHSV Expressing E-Cadherin | 000 | 5 | NIH | 10/28/2024 | $0 |
| | 2025 | 2023 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R35CA210087 | Human natural killer cells: Advancing biology and clinical applications | 000 | 7 | NIH | 12/9/2024 | $0 |
| | 2025 | 2023 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA225843 | RECQ5-dependent SUMO2 conjugation of PCNA in the resolution of transcription-replication conflicts | 000 | 5 | NIH | 12/16/2024 | $0 |
| | 2025 | 2023 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | K99AI159139 | Immune Evasion Mechanisms of KSHV Complement and Fc-Receptor Proteins | 000 | 2 | NIH | 10/24/2024 | $0 |
| | 2025 | 2022 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01HL137723 | Role of the Xbp1s/GFAT1 axis in pathological cardiac remodelling | 000 | 7 | NIH | 1/12/2025 | $122,301 |
| | 2025 | 2022 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R21CA261797 | Remote monitoring of cardiac function in childhood cancer survivors | 000 | 2 | NIH | 11/5/2024 | $0 |
| | 2025 | 2022 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R21CA260447 | A Pilot Study to Evaluate the Benefits of Phytocannabinoids for the Treatment of Chronic Chemotherapy-Induced Peripheral Neuropathy | 000 | 1 | NIH | 12/19/2024 | $0 |
| | 2025 | 2021 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01HL137723 | Role of the Xbp1s/GFAT1 axis in pathological cardiac remodelling | 001 | 6 | NIH | 1/12/2025 | -$122,301 |
| | 2025 | 2021 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R21AI161075 | Develop novel inhaled neutralizing RNA therapeutics against COVID-19 | 000 | 1 | NIH | 11/7/2024 | $0 |
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| Issue Date FY: 2024 ( Subtotal = $77,354,323 ) (Continued on the next page) |
| | 2024 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R33AG059206 | Geriatric Oncology Research Infrastructure to Improve Clinical Care | 002 | 7 | NIH | 6/27/2024 | $631,571 |
| | 2024 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01AI146313 | The role of miR-142 in regulatory T cell Development and function | 000 | 5 | NIH | 8/16/2024 | $440,000 |
| | 2024 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01AI151013 | KSHV Subunit Vaccine Candidates to Elicit Potent Humoral Immune Reponses against KSHV Infection | 001 | 4 | NIH | 5/23/2024 | $84,892 |
| | 2024 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01AI151013 | KSHV Subunit Vaccine Candidates to Elicit Potent Humoral Immune Reponses against KSHV Infection | 000 | 4 | NIH | 2/1/2024 | $764,036 |
| | 2024 | 2024 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA249501 | Self-Management to Optimize Survivorship Care and Outcomes in Lung and Colorectal Cancer | 000 | 5 | NIH | 3/25/2024 | $707,468 |
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