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 | Issue Date FY: 2025 ( Subtotal = $29,985,816 ) (Continued on the next page) |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01DK134652 | Role of trefoil factor family proteins in beta cell function. | 000 | 3 | NIH | 11/13/2024 | $511,289 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R21CA280317 | Non-receptor protein tyrosine phosphatases in macrophage-mediated cancer cell phagocytosis. | 000 | 2 | NIH | 2/28/2025 | $224,681 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA073764 | FEN1-mediated Okazaki fragment maturation and its deficiency in cancer | 001 | 27 | NIH | 4/16/2025 | $400,500 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | T32CA221709 | Cancer Metabolism Training Program | 002 | 7 | NIH | 4/7/2025 | $275,859 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA279840 | Okazaki fragment maturation: mutagenesis and cell survival | 000 | 3 | NIH | 3/3/2025 | $493,021 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01LM013876 | An integrated toolkit combining computational systems biology techniques with molecular dynamics simulations to delineate functionality of GPCRs | 000 | 4 | NIH | 3/11/2025 | $336,600 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA292893 | Targeting AMP Synthesis to Overcome Resistance to BH3 Mimetics in Acute Myeloid Leukemia | 000 | 1 | NIH | 3/10/2025 | $734,435 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01HL170099 | Role of autoreactivity in pathogenesis of chronic graft versus host disease | 000 | 2 | NIH | 2/28/2025 | $791,336 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA297752 | Tumor-Selective Radiosensitization by Targeting Hypoxia in Rectal Cancer | 001 | 1 | NIH | 2/12/2025 | $0 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA297752 | Tumor-Selective Radiosensitization by Targeting Hypoxia in Rectal Cancer | 000 | 1 | NIH | 1/30/2025 | $662,096 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA244576 | Overcoming ibrutinib resistance in mantle cell lymphoma | 000 | 5 | NIH | 1/27/2025 | $405,279 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R35GM156498 | Emergent role of allostery on function of GPCRs and Trimeric G proteins | 000 | 1 | NIH | 1/28/2025 | $445,000 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA278050 | Mechanism and therapeutic opportunities of targeting the Tudor domain | 000 | 3 | NIH | 11/20/2024 | $460,155 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA286160 | Targeting Immune Escape in CML/MPN Transformation | 001 | 2 | NIH | 11/20/2024 | $514,454 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA258981 | The Role of miR-142 in the Transformation of Clonal Hematopoietic Disorders into AML | 001 | 4 | NIH | 12/19/2024 | $488,601 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R21CA282528 | Developing a novel therapeutic strategy for overcoming resistance to PD-1 blockade in Triple-negative breast cancer | 000 | 2 | NIH | 1/24/2025 | $224,681 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA279595 | Targeting Protein Arginine Methyltransferases to Eradicate Acute Myeloid Leukemia | 000 | 2 | NIH | 11/19/2024 | $637,252 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01AI152068 | BCL11B activation as an approach for enhancing the efficacy of immunotherapy | 003 | 6 | NIH | 2/13/2025 | $490,646 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA241845 | Validation of epigenomic biomarkers for thyroid cancer diagnostics | 000 | 4 | NIH | 11/13/2024 | $737,207 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01DK138665 | Targeting bile acid composition to treat metabolic diseases | 000 | 2 | NIH | 12/31/2024 | $599,308 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R37CA292678 | The role, mechanism, and therapeutic potential of METTL1 in acute myeloid leukemia | 000 | 2 | NIH | 5/12/2025 | $434,632 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | UM1CA186717 | Phase 1 and 2 Molecular and Clinical Pharmacodynamic Trials ETCTN | 001 | 9 | NIH | 4/21/2025 | $1,713,060 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | K01DK128387 | The role of Nrf2 in beta cell expansion during pregnancy | 001 | 4 | NIH | 12/6/2024 | $153,554 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA266665 | Engineered anti-PSCA antibodies for immunoPET and targeted therapy of pancreatic cancer | 000 | 4 | NIH | 12/19/2024 | $540,806 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01HL162847 | Pathogenesis, prevention and treatment of corticosteroid-resistant gut GVHD | 000 | 3 | NIH | 12/20/2024 | $771,055 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA258778 | Targeting tumor-associated macrophages for triple-negative breast cancer treatment | 000 | 4 | NIH | 11/12/2024 | $467,633 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | P30CA033572 | Cancer Center Support Grant | 001 | 42 | NIH | 12/23/2024 | $199,548 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | P30CA033572 | Cancer Center Support Grant | 002 | 42 | NIH | 12/26/2024 | $249,999 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | P30CA033572 | Cancer Center Support Grant | 000 | 42 | NIH | 12/20/2024 | $3,536,183 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA269740 | Targeting the Microenvironment/Oncogene Cooperation to treat poor prognosis T-ALL | 000 | 3 | NIH | 2/19/2025 | $467,705 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01ES034793 | Early Life Exposure to Endocrine Disrupting Chemicals: Epigenomic and Transcriptomic Networks and RAGE in Liver Disease | 000 | 2 | NIH | 3/27/2025 | $767,661 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA266783 | Transfer of vaccine-induced immunity from immunocompetent stem cell donor as antiviral immunotherapy to protect high-risk transplant recipients from cytomegalovirus reactivation | 000 | 3 | NIH | 3/31/2025 | $584,019 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01ES033514 | Environmental Chemical Body Burden and Prospective Breast Cancer Risk in the Cancer Prevention Study-3 Cohort | 000 | 4 | NIH | 4/10/2025 | $615,930 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA271497 | The role and therapeutic potential of IGF2BP2 in MLL-rearranged leukemia | 000 | 4 | NIH | 1/24/2025 | $516,429 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01NS132083 | Biological function and regulation of PRMT9 in synapse development | 000 | 2 | NIH | 3/4/2025 | $535,402 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA246553 | Developing BRAF mutant and BRAF wild-type selective strategies for radiosensitization in Anaplastic Thyroid Cancer | 000 | 6 | NIH | 3/28/2025 | $416,701 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA301510 | Discovery and validation of CYP8B1 Inhibitors as probes for targeting Hepatocellular Carcinomas (HCC) | 000 | 1 | NIH | 4/11/2025 | $793,324 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA299039 | The role of IL-6/STAT3 signaling in CIC-DUX4 fusion sarcoma metastasis and immunosuppression | 000 | 1 | NIH | 4/3/2025 | $593,028 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01NS138604 | High Fidelity Genome Editing for the Correction of MECP2 Mutations and Physiologic Regulation of Expression in Rett Syndrome | 000 | 1 | NIH | 4/1/2025 | $738,182 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA228308 | The role of bile acid metabolomics in graft-versus-host disease | 000 | 8 | NIH | 3/31/2025 | $527,259 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA292596 | Anti-CD38 Radioimmunotherapy and Total Marrow Irradiation for Treatment of Relapsed and Refractory Acute Myelogenous Leukemia | 000 | 1 | NIH | 3/7/2025 | $738,698 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R25CA217270 | Preparing Oncology Advanced Practice Nurses as Generalists in Palliative Care | 000 | 8 | NIH | 1/10/2025 | $291,600 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R25CA217270 | Preparing Oncology Advanced Practice Nurses as Generalists in Palliative Care | 001 | 8 | NIH | 2/12/2025 | $0 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R37CA233691 | Combinational targeting the feed forward epigenetic circuitry in mixed lineage leukemia | 000 | 7 | NIH | 12/12/2024 | $362,340 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | T32CA186895 | DNA Damage Response and Oncogenic Signaling | 000 | 9 | NIH | 3/28/2025 | $245,477 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA269569 | BAFF-R CAR T cell therapy for ALL | 000 | 4 | NIH | 3/21/2025 | $609,861 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01HL171309 | Integrative role of Rps6kb1 in pathological cardiac remodeling | 000 | 2 | NIH | 4/24/2025 | $761,883 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R35GM156316 | Protein arginine methylation in transcription and RNA metabolism | 000 | 1 | NIH | 1/23/2025 | $445,000 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R03DE034794 | Protein Phosphoribosylation: Characterization of a novel protein modification | 000 | 1 | NIH | 3/24/2025 | $178,000 |
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