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 | Issue Date FY: 2025 ( Subtotal = $59,706,733 ) (Continued on the next page) |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | T32DK131943 | DIABETES PREVENTION / RISK / OMICS / METABOLISM / THERAPY (PROMT) INTERDISCIPLINARY TRAINING | 000 | 3 | NIH | 7/3/2025 | $152,204 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA298313 | Targeting Tumor-Associated Macrophages to Treat Lymphoma | 000 | 1 | NIH | 7/25/2025 | $702,495 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01ES034793 | Early Life Exposure to Endocrine Disrupting Chemicals: Epigenomic and Transcriptomic Networks and RAGE in Liver Disease | 000 | 2 | NIH | 3/27/2025 | $767,661 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA282450 | Define the oncogenic role of METTL3 in the pathogenesis of chronic lymphocytic leukemia | 000 | 3 | NIH | 6/30/2025 | $648,241 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA266783 | Transfer of vaccine-induced immunity from immunocompetent stem cell donor as antiviral immunotherapy to protect high-risk transplant recipients from cytomegalovirus reactivation | 001 | 3 | NIH | 5/23/2025 | $64,891 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01HL164895 | A Novel Bone Marrow Transplantation Approach for Sickle Cell Disease Using Targeted Marrow Irradiation | 001 | 3 | NIH | 7/25/2025 | $343,450 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA266783 | Transfer of vaccine-induced immunity from immunocompetent stem cell donor as antiviral immunotherapy to protect high-risk transplant recipients from cytomegalovirus reactivation | 000 | 3 | NIH | 3/31/2025 | $584,019 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA271443 | Exosomal biomarkers for the early detection of hepatocellular carcinoma | 000 | 3 | NIH | 8/6/2025 | $727,919 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01DK133885 | Extracellular Vesicle-mediated islet immune cross talk in Type 1 Diabetes pathogenesis | 000 | 4 | NIH | 5/30/2025 | $747,900 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01ES033514 | Environmental Chemical Body Burden and Prospective Breast Cancer Risk in the Cancer Prevention Study-3 Cohort | 000 | 4 | NIH | 4/10/2025 | $615,930 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA271497 | The role and therapeutic potential of IGF2BP2 in MLL-rearranged leukemia | 001 | 4 | NIH | 5/29/2025 | $57,380 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA271497 | The role and therapeutic potential of IGF2BP2 in MLL-rearranged leukemia | 000 | 4 | NIH | 1/24/2025 | $516,429 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA255250 | Identifying and engaging a universal adjuvant for breaking macrophage immune tolerance in cancer | 000 | 5 | NIH | 6/10/2025 | $431,501 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01HL173308 | Novel mechanisms and therapeutics for Tyrosine Kinase Inhibitor-induced Cardiotoxicity | 000 | 1 | NIH | 5/9/2025 | $697,952 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01AG072291 | Develop age-relevant glial cellular models using human directly reprogrammed cells | 001 | 5 | NIH | 6/11/2025 | $35,200 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01AG072291 | Develop age-relevant glial cellular models using human directly reprogrammed cells | 000 | 5 | NIH | 5/12/2025 | $396,000 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01NS132083 | Biological function and regulation of PRMT9 in synapse development | 000 | 2 | NIH | 3/4/2025 | $535,402 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA246553 | Developing BRAF mutant and BRAF wild-type selective strategies for radiosensitization in Anaplastic Thyroid Cancer | 001 | 6 | NIH | 5/28/2025 | $46,297 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA246553 | Developing BRAF mutant and BRAF wild-type selective strategies for radiosensitization in Anaplastic Thyroid Cancer | 000 | 6 | NIH | 3/28/2025 | $416,701 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA262754 | The role of CEACAM1 in oncogenic B-cell receptor signaling and immunotherapy in mantle cell lymphoma | 000 | 5 | NIH | 7/1/2025 | $401,561 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA253545 | Repurposing Leflunomide to Delay Progression of Smoldering Multiple Myeloma in African Americans | 000 | 4 | NIH | 7/24/2025 | $677,645 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01LM013876 | An integrated toolkit combining computational systems biology techniques with molecular dynamics simulations to delineate functionality of GPCRs | 001 | 4 | NIH | 6/26/2025 | $37,400 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01LM013876 | An integrated toolkit combining computational systems biology techniques with molecular dynamics simulations to delineate functionality of GPCRs | 000 | 4 | NIH | 3/11/2025 | $336,600 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA301510 | Discovery and validation of CYP8B1 Inhibitors as probes for targeting Hepatocellular Carcinomas (HCC) | 000 | 1 | NIH | 4/11/2025 | $793,324 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA299039 | The role of IL-6/STAT3 signaling in CIC-DUX4 fusion sarcoma metastasis and immunosuppression | 000 | 1 | NIH | 4/3/2025 | $593,028 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA256989 | Elucidating the role of DNAPKcs in chromosomal break end joining and clastogen resistance | 001 | 5 | NIH | 6/12/2025 | $402,600 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA269569 | BAFF-R CAR T cell therapy for ALL | 001 | 4 | NIH | 5/28/2025 | $67,762 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA269569 | BAFF-R CAR T cell therapy for ALL | 000 | 4 | NIH | 3/21/2025 | $609,861 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R35GM156316 | Protein arginine methylation in transcription and RNA metabolism | 000 | 1 | NIH | 1/23/2025 | $445,000 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01HL171309 | Integrative role of Rps6kb1 in pathological cardiac remodeling | 001 | 2 | NIH | 7/3/2025 | $84,653 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01HL171309 | Integrative role of Rps6kb1 in pathological cardiac remodeling | 000 | 2 | NIH | 4/24/2025 | $761,883 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA292596 | Anti-CD38 Radioimmunotherapy and Total Marrow Irradiation for Treatment of Relapsed and Refractory Acute Myelogenous Leukemia | 000 | 1 | NIH | 3/7/2025 | $738,698 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | T32CA186895 | DNA Damage Response and Oncogenic Signaling | 001 | 9 | NIH | 5/22/2025 | $4,056 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | T32CA186895 | DNA Damage Response and Oncogenic Signaling | 000 | 9 | NIH | 3/28/2025 | $245,477 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R35CA210087 | Human natural killer cells: Advancing biology and clinical applications | 001 | 8 | NIH | 7/21/2025 | $886,438 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R37CA233691 | Combinational Targeting the Feed-forward Epigenetic Circuitry in Mixed Lineage Leukemia | 002 | 7 | NIH | 6/30/2025 | $40,260 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R37CA233691 | Combinational Targeting the Feed-forward Epigenetic Circuitry in Mixed Lineage Leukemia | 000 | 7 | NIH | 12/12/2024 | $362,340 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R25CA217270 | Preparing Oncology Advanced Practice Nurses as Generalists in Palliative Care | 003 | 8 | NIH | 7/2/2025 | $32,399 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R25CA217270 | Preparing Oncology Advanced Practice Nurses as Generalists in Palliative Care | 000 | 8 | NIH | 1/10/2025 | $291,600 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R25CA217270 | Preparing Oncology Advanced Practice Nurses as Generalists in Palliative Care | 001 | 8 | NIH | 2/12/2025 | $0 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | UG1HL069278 | BMT CTN Core - City of Hope National Medical Center | 002 | 25 | NIH | 7/16/2025 | $264,000 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA283603 | Targeted radiation and immunocytokine therapy for CEA positive malignancies | 000 | 3 | NIH | 8/5/2025 | $676,263 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA205247 | Targeting MicroRNAs to Eradicate Leukemia Stem Cells | 001 | 9 | NIH | 8/11/2025 | $1,011,514 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01HL137723 | Role of the unfolded protein response in pathological cardiac remodeling | 002 | 10 | NIH | 7/25/2025 | $575,395 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA283171 | Attacking the Tumor Cell-Immune Milieu Interface to Overcome Richter's Transformation | 000 | 1 | NIH | 12/16/2024 | $721,723 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R03DE034794 | Protein Phosphoribosylation: Characterization of a novel protein modification | 000 | 1 | NIH | 3/24/2025 | $178,000 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA296394 | Targeting mitochondrial RNA methylation in high-risk acute myeloid leukemia | 000 | 1 | NIH | 12/10/2024 | $487,542 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA296280 | CMV-specific CD19 CAR T cells amplified in vivo using CMV Triplex vaccine for B-NHL | 001 | 1 | NIH | 12/4/2024 | $0 |
| | 2025 | 2025 | BECKMAN RESEARCH INSTITUTE OF THE CITY OF HOPE | 1500 DUARTE RD | DUARTE | CA | 91010-3012 | LOS ANGELES | USA | R01CA296280 | CMV-specific CD19 CAR T cells amplified in vivo using CMV Triplex vaccine for B-NHL | 000 | 1 | NIH | 11/27/2024 | $738,698 |
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